ATE312615T1 - Zusammensetzung zur behandlung von schäden des gelenkknorpels - Google Patents
Zusammensetzung zur behandlung von schäden des gelenkknorpelsInfo
- Publication number
- ATE312615T1 ATE312615T1 AT02751903T AT02751903T ATE312615T1 AT E312615 T1 ATE312615 T1 AT E312615T1 AT 02751903 T AT02751903 T AT 02751903T AT 02751903 T AT02751903 T AT 02751903T AT E312615 T1 ATE312615 T1 AT E312615T1
- Authority
- AT
- Austria
- Prior art keywords
- composition
- treatment
- damage
- articular cartilage
- stem cells
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 210000001188 articular cartilage Anatomy 0.000 title 1
- 210000002901 mesenchymal stem cell Anatomy 0.000 abstract 3
- 210000001612 chondrocyte Anatomy 0.000 abstract 2
- 210000004700 fetal blood Anatomy 0.000 abstract 2
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 210000000845 cartilage Anatomy 0.000 abstract 1
- 230000007547 defect Effects 0.000 abstract 1
- 210000000963 osteoblast Anatomy 0.000 abstract 1
- 210000004409 osteocyte Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Treatment Of Sludge (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20010049147 | 2001-08-14 | ||
| KR20010049148 | 2001-08-14 | ||
| PCT/KR2002/001552 WO2003015802A1 (en) | 2001-08-14 | 2002-08-14 | Composition for treatment of articular cartilage damage |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE312615T1 true ATE312615T1 (de) | 2005-12-15 |
Family
ID=36746258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02751903T ATE312615T1 (de) | 2001-08-14 | 2002-08-14 | Zusammensetzung zur behandlung von schäden des gelenkknorpels |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US7459307B2 (de) |
| EP (1) | EP1416944B1 (de) |
| JP (2) | JP4959916B2 (de) |
| KR (1) | KR100494265B1 (de) |
| CN (1) | CN1272022C (de) |
| AT (1) | ATE312615T1 (de) |
| DE (1) | DE60208042T2 (de) |
| WO (1) | WO2003015802A1 (de) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1229940T3 (da) | 1999-11-15 | 2014-08-18 | Piramal Healthcare Canada Ltd | Temperaturstyret og ph-afhængig selvgelerende, vandig biopolymeropløsning |
| US20030158302A1 (en) | 1999-12-09 | 2003-08-21 | Cyric Chaput | Mineral-polymer hybrid composition |
| ATE243049T1 (de) * | 1999-12-09 | 2003-07-15 | Biosyntech Canada Inc | Mineral-polymer hybrid-zusammensetzung |
| IL153490A0 (en) * | 2000-06-29 | 2003-07-06 | Biosyntech Canada Inc | Composition and method for the repair and regeneration of cartilage and other tissues |
| KR100494265B1 (ko) * | 2001-08-14 | 2005-06-13 | 메디포스트(주) | 관절연골손상 치료용 조성물 |
| ES2287447T3 (es) * | 2002-02-19 | 2007-12-16 | Medipost, Co., Ltd. | Metodos de aislamiento y expansion del cultivo de celulas troncales/madre mesenquimatosas a partir de sangre del cordon umbilical, y metodo de diferenciacion de celulas troncales/madre mesenquimatosas derivadas de sangre del cordon umbilical en diversos tejidos mesenquimatosos. |
| AR047712A1 (es) * | 2002-09-07 | 2006-02-15 | Royal Veterinary College | Metodo de tratamiento de una lesion de tejido esqueletico blando natural administrando una composicion de celulas madre mesenquimatosas |
| JP5048323B2 (ja) * | 2004-03-31 | 2012-10-17 | 株式会社ツーセル | 損傷組織の治療剤と治療方法 |
| US7670596B2 (en) | 2004-04-23 | 2010-03-02 | Bioe, Inc. | Multi-lineage progenitor cells |
| GB0511723D0 (en) * | 2005-06-09 | 2005-07-13 | Smith & Nephew | Placental stem cells |
| CA2628313A1 (en) * | 2005-11-04 | 2007-05-31 | Bio Syntech Canada Inc. | Composition and method for efficient delivery of nucleic acids to cells using chitosan |
| US20070178073A1 (en) * | 2006-02-01 | 2007-08-02 | Samsung Life Public Welfare Foundation | Composition Comprising Separated or Proliferated Cells from Umbilical Cord Blood for Treating Developmental and/or Chronic Lung Disease |
| RU2319465C1 (ru) * | 2006-05-04 | 2008-03-20 | Государственное учреждение Научно-исследовательский институт клинической иммунологии СО РАМН | Способ лечения полнослойных дефектов суставной поверхности |
| KR100834718B1 (ko) * | 2006-09-20 | 2008-06-02 | 세원셀론텍(주) | 뼈 재생을 도모하는 뼈 형성 촉진 세포조성물 및 그 제조방법 |
| JP2010529888A (ja) * | 2007-06-15 | 2010-09-02 | エシコン・インコーポレイテッド | 失禁治療のための組織断片組成物 |
| MX2009013726A (es) * | 2007-06-15 | 2010-01-25 | Ethicon Inc | Composiciones de celulas derivadas de tejido umbilical humano para el tratamiento de la incontinencia. |
| KR100905900B1 (ko) | 2007-07-24 | 2009-07-02 | (주)씨네이처 | 콜라겐을 함유한 관절연골 치료용 이중 지지체 |
| CA2693827A1 (en) * | 2007-07-25 | 2009-01-29 | Bioe, Inc. | Differentiation of multi-lineage progenitor cells to chondrocytes |
| KR20240052847A (ko) | 2008-08-20 | 2024-04-23 | 셀룰래리티 인코포레이티드 | 개선된 세포 조성물 및 그의 제조 방법 |
| KR20100056718A (ko) * | 2008-11-20 | 2010-05-28 | 한국과학기술연구원 | 형상회복력을 갖는 고탄성 생분해성 고분자 지지체 및 이를이용한 관절 연골 손상의 치료 |
| KR20110132579A (ko) * | 2009-03-31 | 2011-12-08 | 코오롱생명과학 주식회사 | 골재생용 조성물 |
| MX357440B (es) * | 2009-05-13 | 2018-07-10 | Medipost Co Ltd | Trombospondina 1 (tsp-1), trombospondina 2 (tsp-2), receptor de interleucina 17b (il-17br) y factor de crecimiento tipo factor de crecimiento epidermico de union a heparina (hb-egf) asociados con actividades de celulas madre y aplicaciones de los mismos. |
| US9040298B2 (en) | 2009-05-29 | 2015-05-26 | Medipost Co., Ltd. | Method of selecting stem cells having high chondrogenic differentiation capability |
| FR2948286B1 (fr) * | 2009-07-27 | 2011-08-26 | Jean-Noel Thorel | Composition injectable associant un agent de comblement et un milieu de croissance des fibroblastes |
| US8574614B2 (en) * | 2010-02-04 | 2013-11-05 | Hwa-Chang Liu | Surgical grafts for repairing chondral defects |
| US10130736B1 (en) | 2010-05-14 | 2018-11-20 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US8883210B1 (en) | 2010-05-14 | 2014-11-11 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US9352003B1 (en) | 2010-05-14 | 2016-05-31 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US8716204B2 (en) | 2010-07-27 | 2014-05-06 | Zimmer, Inc. | Synthetic synovial fluid compositions and methods for making the same |
| CN101934095B (zh) * | 2010-08-31 | 2013-09-18 | 赵亮 | 一种可注射强化型磷石灰/水凝胶微囊组织工程骨及其制备方法和应用 |
| US9446075B2 (en) * | 2011-05-06 | 2016-09-20 | Bioregenerative Sciences | Compositions derived from stem cell released molecules and methods for formulation thereof |
| US8834928B1 (en) | 2011-05-16 | 2014-09-16 | Musculoskeletal Transplant Foundation | Tissue-derived tissugenic implants, and methods of fabricating and using same |
| KR101422689B1 (ko) * | 2011-07-13 | 2014-07-23 | (주)차바이오앤디오스텍 | 콜라겐, 히알루론산 유도체 및 포유류의 탯줄 유래 줄기세포를 포함하는 연골세포치료제 |
| US9545370B2 (en) | 2012-05-08 | 2017-01-17 | BioRegenerative Sciences, Inc. | Bioactive compositions and methods for their preparation and use |
| KR101532556B1 (ko) | 2012-09-03 | 2015-06-30 | 메디포스트(주) | 간엽줄기세포의 배양 방법 |
| CN102899287B (zh) * | 2012-10-24 | 2013-08-21 | 天津和泽干细胞科技有限公司 | 一种诱导间充质干细胞向软骨细胞分化的方法及其在骨关节炎中的应用 |
| WO2015105357A1 (ko) * | 2014-01-08 | 2015-07-16 | 사회복지법인 삼성생명공익재단 | 영양막 기저층으로부터 유래된 줄기세포 및 이를 포함하는 세포치료제 |
| WO2016006788A1 (ko) | 2014-07-07 | 2016-01-14 | 메디포스트(주) | 작은 크기 줄기세포의 발모 촉진능 및 이의 용도 |
| US10918669B2 (en) | 2014-07-25 | 2021-02-16 | Recellerate, Inc. | Methods of treating exercise-induced pulmonary hemorrhage |
| KR101593318B1 (ko) * | 2014-08-26 | 2016-02-17 | 동국대학교 산학협력단 | 서방출 및 생체 적합성이 개선된 카토제닌-키토산 복합체 입자 및 이의 이용 |
| US20220096563A1 (en) * | 2015-02-06 | 2022-03-31 | Kolon Life Science, Inc. | Composition for treating inflammatory disease induced by hyperimmune response |
| CA2986702C (en) | 2015-05-21 | 2023-04-04 | David Wang | Modified demineralized cortical bone fibers |
| WO2017062493A1 (en) * | 2015-10-05 | 2017-04-13 | Board Of Regents, The University Of Texas System | Micro-and nano-device for cartilage injury detection and treatment |
| CN105796600B (zh) * | 2016-04-28 | 2020-02-28 | 博雅干细胞科技有限公司 | 使用干细胞治疗骨关节炎的方法和组合物 |
| US20210228637A1 (en) * | 2018-06-05 | 2021-07-29 | Medipost Co., Ltd | Pharmaceutical composition comprising hyaluronic acid and stem cells for treating cartilage damage-associated disease |
| KR20200000823A (ko) | 2018-06-25 | 2020-01-03 | 주식회사 씨아이에스티이엠 | 인간 유도 만능 줄기세포로부터 연골세포의 펠렛을 제조하는 방법 및 이의 용도 |
| IT201800020722A1 (it) * | 2018-12-21 | 2020-06-21 | Assunta Borzacchiello | Biomateriale e suo utilizzo nel trattamento di patologie polmonari |
| IT201900002697A1 (it) * | 2019-02-25 | 2020-08-25 | Scuola Superiore Di Studi Univ E Di Perfezionamento Santanna | Materiale e sistema per il trattamento terapeutico di articolazioni |
| JP7506431B2 (ja) * | 2019-08-01 | 2024-06-26 | メディクリニア カンパニー リミテッド | ヒアルロン酸とプルロニックを含む関節及び軟骨損傷の予防又は治療用組成物 |
| KR102156602B1 (ko) * | 2019-10-17 | 2020-09-16 | 전북대학교산학협력단 | miRNA-140-5p가 함유된 젤란검 하이드로겔 조성물과 이를 이용한 연골손상 치료용 조성물 |
| CN111676190B (zh) * | 2020-06-09 | 2022-04-22 | 生物岛实验室 | 一种干细胞向成软骨分化的诱导剂及其应用 |
| EP4275692A4 (de) | 2021-01-08 | 2024-12-04 | Seoul National University R & DB Foundation | Auf getrockneten zellen basierendes therapeutikum zur behandlung von osteoarthritis |
| CN114569795B (zh) * | 2022-03-08 | 2023-03-24 | 香港理工大学深圳研究院 | 一种双层骨软骨支架材料及其制备方法与应用 |
| KR20250132868A (ko) | 2024-02-29 | 2025-09-05 | 가톨릭대학교 산학협력단 | 자성 나노 입자가 함입된 코중격 연골세포를 유효성분으로 포함하는 연골 질환 치료용 약학적 조성물 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5902741A (en) * | 1986-04-18 | 1999-05-11 | Advanced Tissue Sciences, Inc. | Three-dimensional cartilage cultures |
| US4816437A (en) * | 1987-06-01 | 1989-03-28 | Trustees Of Boston University | Methods for inducing general and localized bone apposition in-vivo |
| US5004681B1 (en) * | 1987-11-12 | 2000-04-11 | Biocyte Corp | Preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood |
| US5906934A (en) * | 1995-03-14 | 1999-05-25 | Morphogen Pharmaceuticals, Inc. | Mesenchymal stem cells for cartilage repair |
| US5842477A (en) * | 1996-02-21 | 1998-12-01 | Advanced Tissue Sciences, Inc. | Method for repairing cartilage |
| US5919702A (en) * | 1996-10-23 | 1999-07-06 | Advanced Tissue Science, Inc. | Production of cartilage tissue using cells isolated from Wharton's jelly |
| EP0989855A4 (de) | 1997-05-13 | 2002-06-12 | Osiris Therapeutics Inc | Regeneration von knorpel bei osteoarthritis mittels menschlicher mesenchymaler stammzellen |
| US5985208A (en) * | 1998-08-27 | 1999-11-16 | Alliedsignal Inc. | Process for debinding and sintering metal injection molded parts made with an aqueous binder |
| EP1099754A1 (de) * | 1999-11-10 | 2001-05-16 | Universiteit Leiden | Mesenchym-Stammzellen und/oder Vorlaüferzellen, ihre Isolierung und ihre Verwendung |
| KR100494265B1 (ko) * | 2001-08-14 | 2005-06-13 | 메디포스트(주) | 관절연골손상 치료용 조성물 |
-
2002
- 2002-08-14 KR KR10-2002-0048062A patent/KR100494265B1/ko not_active Expired - Lifetime
- 2002-08-14 CN CNB028158342A patent/CN1272022C/zh not_active Expired - Lifetime
- 2002-08-14 AT AT02751903T patent/ATE312615T1/de not_active IP Right Cessation
- 2002-08-14 WO PCT/KR2002/001552 patent/WO2003015802A1/en not_active Ceased
- 2002-08-14 EP EP02751903A patent/EP1416944B1/de not_active Expired - Lifetime
- 2002-08-14 US US10/485,816 patent/US7459307B2/en not_active Expired - Lifetime
- 2002-08-14 DE DE60208042T patent/DE60208042T2/de not_active Expired - Lifetime
- 2002-08-14 JP JP2003520761A patent/JP4959916B2/ja not_active Expired - Lifetime
-
2008
- 2008-09-24 US US12/237,207 patent/US20090022698A1/en not_active Abandoned
- 2008-09-24 US US12/237,225 patent/US20090047261A1/en not_active Abandoned
- 2008-09-24 US US12/237,182 patent/US20090060885A1/en not_active Abandoned
-
2012
- 2012-01-18 JP JP2012008349A patent/JP5597817B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012107026A (ja) | 2012-06-07 |
| US20090047261A1 (en) | 2009-02-19 |
| EP1416944A4 (de) | 2004-10-27 |
| EP1416944B1 (de) | 2005-12-14 |
| JP4959916B2 (ja) | 2012-06-27 |
| CN1543353A (zh) | 2004-11-03 |
| US7459307B2 (en) | 2008-12-02 |
| KR20030015160A (ko) | 2003-02-20 |
| JP5597817B2 (ja) | 2014-10-01 |
| KR100494265B1 (ko) | 2005-06-13 |
| DE60208042D1 (de) | 2006-01-19 |
| CN1272022C (zh) | 2006-08-30 |
| EP1416944A1 (de) | 2004-05-12 |
| WO2003015802A1 (en) | 2003-02-27 |
| US20090022698A1 (en) | 2009-01-22 |
| JP2005501101A (ja) | 2005-01-13 |
| US20040151703A1 (en) | 2004-08-05 |
| US20090060885A1 (en) | 2009-03-05 |
| DE60208042T2 (de) | 2006-08-17 |
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