ATE312615T1 - Zusammensetzung zur behandlung von schäden des gelenkknorpels - Google Patents

Zusammensetzung zur behandlung von schäden des gelenkknorpels

Info

Publication number
ATE312615T1
ATE312615T1 AT02751903T AT02751903T ATE312615T1 AT E312615 T1 ATE312615 T1 AT E312615T1 AT 02751903 T AT02751903 T AT 02751903T AT 02751903 T AT02751903 T AT 02751903T AT E312615 T1 ATE312615 T1 AT E312615T1
Authority
AT
Austria
Prior art keywords
composition
treatment
damage
articular cartilage
stem cells
Prior art date
Application number
AT02751903T
Other languages
English (en)
Inventor
Chul-Won Ha
Yoon-Sun Yang
Sung-Eun Yang
Original Assignee
Medipost Co Ltd
Chul-Won Ha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medipost Co Ltd, Chul-Won Ha filed Critical Medipost Co Ltd
Application granted granted Critical
Publication of ATE312615T1 publication Critical patent/ATE312615T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Treatment Of Sludge (AREA)
AT02751903T 2001-08-14 2002-08-14 Zusammensetzung zur behandlung von schäden des gelenkknorpels ATE312615T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20010049147 2001-08-14
KR20010049148 2001-08-14
PCT/KR2002/001552 WO2003015802A1 (en) 2001-08-14 2002-08-14 Composition for treatment of articular cartilage damage

Publications (1)

Publication Number Publication Date
ATE312615T1 true ATE312615T1 (de) 2005-12-15

Family

ID=36746258

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02751903T ATE312615T1 (de) 2001-08-14 2002-08-14 Zusammensetzung zur behandlung von schäden des gelenkknorpels

Country Status (8)

Country Link
US (4) US7459307B2 (de)
EP (1) EP1416944B1 (de)
JP (2) JP4959916B2 (de)
KR (1) KR100494265B1 (de)
CN (1) CN1272022C (de)
AT (1) ATE312615T1 (de)
DE (1) DE60208042T2 (de)
WO (1) WO2003015802A1 (de)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1375301A (en) 1999-11-15 2001-05-30 Bio Syntech Canada Inc Temperature-controlled and ph-dependant self-gelling biopolymeric aqueous solution
DE60003459T2 (de) * 1999-12-09 2004-05-06 Biosyntech Canada Inc., Laval Mineral-polymer hybrid-zusammensetzung
US20030158302A1 (en) 1999-12-09 2003-08-21 Cyric Chaput Mineral-polymer hybrid composition
DK1294414T3 (da) * 2000-06-29 2006-07-24 Biosyntech Canada Inc Præparat og fremgangsmåde til heling og regenerering af brusk og andre væv
WO2003015802A1 (en) * 2001-08-14 2003-02-27 Medipost, Co., Ltd. Composition for treatment of articular cartilage damage
AU2003207399A1 (en) * 2002-02-19 2003-09-09 Medipost Co., Ltd. Isolation and culture-expansion methods of mesenchymal stem/progenitor cells from umbilical cord blood, and differentiation method of umbilical cord blood-derived mesenchymal stem/progenitor cells into various mesenchymal tissues
AR047712A1 (es) 2002-09-07 2006-02-15 Royal Veterinary College Metodo de tratamiento de una lesion de tejido esqueletico blando natural administrando una composicion de celulas madre mesenquimatosas
WO2005094888A1 (ja) 2004-03-31 2005-10-13 Two Cells Co. Ltd. 損傷組織の治療剤と治療方法
US7670596B2 (en) 2004-04-23 2010-03-02 Bioe, Inc. Multi-lineage progenitor cells
GB0511723D0 (en) * 2005-06-09 2005-07-13 Smith & Nephew Placental stem cells
WO2007059605A1 (en) * 2005-11-04 2007-05-31 Bio Syntech Canada Inc. Composition and method for efficient delivery of nucleic acids to cells using chitosan
US20070178073A1 (en) * 2006-02-01 2007-08-02 Samsung Life Public Welfare Foundation Composition Comprising Separated or Proliferated Cells from Umbilical Cord Blood for Treating Developmental and/or Chronic Lung Disease
RU2319465C1 (ru) * 2006-05-04 2008-03-20 Государственное учреждение Научно-исследовательский институт клинической иммунологии СО РАМН Способ лечения полнослойных дефектов суставной поверхности
KR100834718B1 (ko) * 2006-09-20 2008-06-02 세원셀론텍(주) 뼈 재생을 도모하는 뼈 형성 촉진 세포조성물 및 그 제조방법
CA2691361A1 (en) * 2007-06-15 2008-12-24 Ethicon, Inc. Tissue fragment compositions for the treatment of incontinence
EP2155217A2 (de) * 2007-06-15 2010-02-24 Ethicon, Inc. Aus menschlichem nabelschnurgewebe abgeleitete zellzusammensetzungen zur behandlung von harninkontinenz
KR100905900B1 (ko) 2007-07-24 2009-07-02 (주)씨네이처 콜라겐을 함유한 관절연골 치료용 이중 지지체
CA2693827A1 (en) * 2007-07-25 2009-01-29 Bioe, Inc. Differentiation of multi-lineage progenitor cells to chondrocytes
NZ591292A (en) 2008-08-20 2012-10-26 Anthrogenesis Corp Improved cell composition and methods of making the same
KR20100056718A (ko) * 2008-11-20 2010-05-28 한국과학기술연구원 형상회복력을 갖는 고탄성 생분해성 고분자 지지체 및 이를이용한 관절 연골 손상의 치료
KR20110132579A (ko) * 2009-03-31 2011-12-08 코오롱생명과학 주식회사 골재생용 조성물
CA2761610C (en) * 2009-05-13 2020-12-29 Medipost Co., Ltd. Tsp-1, tsp-2, il-17br and hb-egf associated with stem cell activities and applications thereof
US9040298B2 (en) 2009-05-29 2015-05-26 Medipost Co., Ltd. Method of selecting stem cells having high chondrogenic differentiation capability
FR2948286B1 (fr) * 2009-07-27 2011-08-26 Jean-Noel Thorel Composition injectable associant un agent de comblement et un milieu de croissance des fibroblastes
US8574614B2 (en) * 2010-02-04 2013-11-05 Hwa-Chang Liu Surgical grafts for repairing chondral defects
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8716204B2 (en) 2010-07-27 2014-05-06 Zimmer, Inc. Synthetic synovial fluid compositions and methods for making the same
CN101934095B (zh) * 2010-08-31 2013-09-18 赵亮 一种可注射强化型磷石灰/水凝胶微囊组织工程骨及其制备方法和应用
US9446075B2 (en) * 2011-05-06 2016-09-20 Bioregenerative Sciences Compositions derived from stem cell released molecules and methods for formulation thereof
US8834928B1 (en) 2011-05-16 2014-09-16 Musculoskeletal Transplant Foundation Tissue-derived tissugenic implants, and methods of fabricating and using same
CN103796659A (zh) * 2011-07-13 2014-05-14 车比奥及戴奥斯泰有限公司 包含胶原、透明质酸衍生物和哺乳动物脐带来源干细胞的软骨细胞治疗物
US9545370B2 (en) 2012-05-08 2017-01-17 BioRegenerative Sciences, Inc. Bioactive compositions and methods for their preparation and use
KR101532556B1 (ko) 2012-09-03 2015-06-30 메디포스트(주) 간엽줄기세포의 배양 방법
CN102899287B (zh) * 2012-10-24 2013-08-21 天津和泽干细胞科技有限公司 一种诱导间充质干细胞向软骨细胞分化的方法及其在骨关节炎中的应用
EP3093340B1 (de) * 2014-01-08 2020-10-14 Samsung Life Public Welfare Foundation Stammzellen aus dem basalen teil einer chorionischen trophoblastschicht und zelltherapie damit
WO2016006788A1 (ko) 2014-07-07 2016-01-14 메디포스트(주) 작은 크기 줄기세포의 발모 촉진능 및 이의 용도
EP3209768A1 (de) 2014-07-25 2017-08-30 Recellerate Inc. Verfahren zur behandlung von körpertrainingsinduzierter pulmonaler hämorrhagie
KR101593318B1 (ko) 2014-08-26 2016-02-17 동국대학교 산학협력단 서방출 및 생체 적합성이 개선된 카토제닌-키토산 복합체 입자 및 이의 이용
US20220096563A1 (en) * 2015-02-06 2022-03-31 Kolon Life Science, Inc. Composition for treating inflammatory disease induced by hyperimmune response
CA2986702C (en) 2015-05-21 2023-04-04 David Wang Modified demineralized cortical bone fibers
CN108697804B (zh) * 2015-10-05 2022-11-15 德克萨斯州立大学董事会 用于软骨损伤的检测和治疗的微米和纳米装置
CN105796600B (zh) * 2016-04-28 2020-02-28 博雅干细胞科技有限公司 使用干细胞治疗骨关节炎的方法和组合物
US12303534B2 (en) 2018-06-05 2025-05-20 Medipost Co., Ltd Pharmaceutical composition comprising mesenchymal stem cells as effective ingredient for prevention or treatment of inflammatory disease
JP7350344B2 (ja) 2018-06-25 2023-09-26 イップスセル インコーポレイテッド ヒト誘導万能幹細胞から軟骨細胞のペレットを製造する方法およびその用途
IT201800020722A1 (it) * 2018-12-21 2020-06-21 Assunta Borzacchiello Biomateriale e suo utilizzo nel trattamento di patologie polmonari
IT201900002697A1 (it) * 2019-02-25 2020-08-25 Scuola Superiore Di Studi Univ E Di Perfezionamento Santanna Materiale e sistema per il trattamento terapeutico di articolazioni
KR102517764B1 (ko) * 2019-08-01 2023-04-04 하유진 히알루론산과 플루로닉을 포함하는 관절 및 연골 손상 예방 또는 치료용 조성물
KR102156602B1 (ko) * 2019-10-17 2020-09-16 전북대학교산학협력단 miRNA-140-5p가 함유된 젤란검 하이드로겔 조성물과 이를 이용한 연골손상 치료용 조성물
CN111676190B (zh) * 2020-06-09 2022-04-22 生物岛实验室 一种干细胞向成软骨分化的诱导剂及其应用
KR102925701B1 (ko) 2021-01-08 2026-02-10 서울대학교 산학협력단 골관절염 치료를 위한 건조된 세포 분비물 기반 치료제
CN114569795B (zh) * 2022-03-08 2023-03-24 香港理工大学深圳研究院 一种双层骨软骨支架材料及其制备方法与应用
KR20250132868A (ko) 2024-02-29 2025-09-05 가톨릭대학교 산학협력단 자성 나노 입자가 함입된 코중격 연골세포를 유효성분으로 포함하는 연골 질환 치료용 약학적 조성물
WO2026089483A1 (ko) 2024-10-23 2026-04-30 주식회사 바이오솔루션 연골화 자극 스페로이드 및/또는 이의 유래물질을 포함하는 골관절염 예방, 개선 또는 치료용 약제

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5902741A (en) * 1986-04-18 1999-05-11 Advanced Tissue Sciences, Inc. Three-dimensional cartilage cultures
US4816437A (en) * 1987-06-01 1989-03-28 Trustees Of Boston University Methods for inducing general and localized bone apposition in-vivo
US5004681B1 (en) * 1987-11-12 2000-04-11 Biocyte Corp Preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood
US5906934A (en) 1995-03-14 1999-05-25 Morphogen Pharmaceuticals, Inc. Mesenchymal stem cells for cartilage repair
US5842477A (en) * 1996-02-21 1998-12-01 Advanced Tissue Sciences, Inc. Method for repairing cartilage
US5919702A (en) * 1996-10-23 1999-07-06 Advanced Tissue Science, Inc. Production of cartilage tissue using cells isolated from Wharton's jelly
AU7481098A (en) * 1997-05-13 1998-12-08 Case Western Reserve University Osteoarthritis cartilage regeneration using human mesenchymal stem ce lls
US5985208A (en) * 1998-08-27 1999-11-16 Alliedsignal Inc. Process for debinding and sintering metal injection molded parts made with an aqueous binder
EP1099754A1 (de) * 1999-11-10 2001-05-16 Universiteit Leiden Mesenchym-Stammzellen und/oder Vorlaüferzellen, ihre Isolierung und ihre Verwendung
WO2003015802A1 (en) * 2001-08-14 2003-02-27 Medipost, Co., Ltd. Composition for treatment of articular cartilage damage

Also Published As

Publication number Publication date
JP4959916B2 (ja) 2012-06-27
KR20030015160A (ko) 2003-02-20
EP1416944B1 (de) 2005-12-14
JP2005501101A (ja) 2005-01-13
DE60208042D1 (de) 2006-01-19
WO2003015802A1 (en) 2003-02-27
CN1543353A (zh) 2004-11-03
US20090060885A1 (en) 2009-03-05
JP2012107026A (ja) 2012-06-07
EP1416944A1 (de) 2004-05-12
US20040151703A1 (en) 2004-08-05
KR100494265B1 (ko) 2005-06-13
CN1272022C (zh) 2006-08-30
EP1416944A4 (de) 2004-10-27
JP5597817B2 (ja) 2014-10-01
US20090022698A1 (en) 2009-01-22
US20090047261A1 (en) 2009-02-19
US7459307B2 (en) 2008-12-02
DE60208042T2 (de) 2006-08-17

Similar Documents

Publication Publication Date Title
DE60208042D1 (de) Zusammensetzung zur behandlung von schäden des gelenkknorpels
ATE328067T1 (de) Isolierung von mesenchymalen stammzellen und deren verwendung
ATE414089T1 (de) Verwendung von rapamycin und dessen derivaten zur behandlung von knochenverlust
ATE290353T1 (de) In vitro heilung von knochen- und/oder knorpelschäden
DE60137430D1 (de) Gewebeimplant zur wiederherstellung von knorpelgewebe
NZ527565A (en) Methods and devices for tissue repair
DE69841850D1 (de) Differenzierung in osteoblasten der fettgewebe-stromalen zellen und ihre verwendungen
DK1148897T3 (da) Fremgangsmåder og sammensætninger til heling og reparation af artikulært brusk
WO1998008469A3 (en) Method, instruments and kit for autologous transplantation
ATE382681T1 (de) Verbesserung der herzfunktion durch transplantation mesenchymaler stammzellen
ATE364410T1 (de) Verfahren zur behandlung eines patienten mit einem kultivierten bindegewebe-konstrukt
AU5723601A (en) Joint repair using mesenchymal stem cells
MEP8209A (en) Modified factor viii
DE602006016735D1 (de) Verfahren zur proliferation von stammzellen
NO20013744D0 (no) Fremgangsmåter og blandinger for heling og reparasjon av leddbrusk
DE60218153D1 (de) Verwendung von proteasom-inhibitoren zur behandlung des trockenen auges
TR200200278T2 (tr) Kalsilitik bileşimler
ATE264101T1 (de) Verwendung von thioamidoxazolidinonen zur behandlung von knochenresorption und osteoporose
WO2003029432A3 (en) Human mesenchymal progenitor cell
WO2001083707A3 (en) Chondrocyte cultures and anti-angiogenic fractions therefrom
DE50212407D1 (de) Verwendung eines Reinigungsmittelkonzentrats und Verfahren zur Reinigung chirurgischer Instrumente
EA200701598A1 (ru) Способ и композиция для восстановления эпителиальных и других клеток и тканей
FR2860423B1 (fr) Implant destine au traitement des lesions isolees du cartilage par greffe de chondrocytes
DK0795008T3 (da) Humane hypertrofe chondrocyt-cellelinjer
DE60000877D1 (de) Material für knochentransplantate aus calciumphosphat-keramik und knochengewebe

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties