ATE244023T1 - Ternäre radiopharmazeutische komplexe - Google Patents

Ternäre radiopharmazeutische komplexe

Info

Publication number
ATE244023T1
ATE244023T1 AT97915928T AT97915928T ATE244023T1 AT E244023 T1 ATE244023 T1 AT E244023T1 AT 97915928 T AT97915928 T AT 97915928T AT 97915928 T AT97915928 T AT 97915928T AT E244023 T1 ATE244023 T1 AT E244023T1
Authority
AT
Austria
Prior art keywords
chelator
radiopharmaceuticals
transition metal
biologically active
ancillary ligand
Prior art date
Application number
AT97915928T
Other languages
English (en)
Inventor
David Scott Edwards
Shuang Liu
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/808,699 external-priority patent/US5879659A/en
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Application granted granted Critical
Publication of ATE244023T1 publication Critical patent/ATE244023T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT97915928T 1996-03-13 1997-03-12 Ternäre radiopharmazeutische komplexe ATE244023T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1336096P 1996-03-13 1996-03-13
US64686696A 1996-05-08 1996-05-08
US08/808,699 US5879659A (en) 1996-03-13 1997-02-28 Ternary radiopharmaceutical complexes
PCT/US1997/003915 WO1997033627A2 (en) 1996-03-13 1997-03-12 New ternary radiopharmaceutical complexes

Publications (1)

Publication Number Publication Date
ATE244023T1 true ATE244023T1 (de) 2003-07-15

Family

ID=27359839

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97915928T ATE244023T1 (de) 1996-03-13 1997-03-12 Ternäre radiopharmazeutische komplexe

Country Status (8)

Country Link
EP (1) EP0888130B1 (de)
JP (1) JP2000507233A (de)
AT (1) ATE244023T1 (de)
AU (1) AU2323197A (de)
CA (1) CA2249025A1 (de)
DE (1) DE69723242T2 (de)
ES (1) ES2201284T3 (de)
WO (1) WO1997033627A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5739313A (en) 1995-11-13 1998-04-14 Regents Of The University Of Minnesota Radionuclide labeling of vitamin B12 and coenzymes thereof
US6251364B1 (en) 1999-03-29 2001-06-26 Dupont Pharmaceuticals Company Ternary ligand complexes useful as radiopharmaceuticals
US6806363B1 (en) 1999-04-16 2004-10-19 Mayo Foundation For Medical Education & Research Cobalamin conjugates useful as antitumor agents
US7591995B2 (en) 1999-10-15 2009-09-22 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging and therapeutic agents
AU785505B2 (en) 1999-10-15 2009-02-26 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging and therapeutic agents
EP1334114A2 (de) 2000-10-25 2003-08-13 Mayo Foundation For Medical Education And Research Transcobalamin-bindende konjugate zur behandlung abnormaler zellulärer proliferation
GB0031592D0 (en) * 2000-12-28 2001-02-07 Nycomed Amersham Plc Stabilised radiopharmaceutical compositions
US6838074B2 (en) 2001-08-08 2005-01-04 Bristol-Myers Squibb Company Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent
MXPA04001113A (es) 2001-08-08 2004-07-08 Bristol Myers Squibb Pharma Co Formacion de imagenes simultaneas de perfusion cardiaca y agente formador de imagenes dirigido al receptor de vitronectina.
AU2009246397B2 (en) 2008-05-13 2013-01-17 University Of Kansas Metal abstraction peptide (MAP) tag and associated methods
WO2013181461A2 (en) 2012-06-01 2013-12-05 University Of Kansas Metal abstraction peptide with superoxide dismutase activity

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8721591A (en) * 1990-09-14 1992-04-15 Mallinckrodt Medical, Inc. Novel nitrogen-sulfur ligands useful in radiographic imaging agents
DE69332470D1 (de) * 1992-02-06 2002-12-12 Biosynthema Inc Liganden zur verbesserung der metallchelatbildungskinetik
GB9209641D0 (en) * 1992-05-02 1992-06-17 Johnson Matthey Plc Improvements in radiolabelling
AU6128694A (en) * 1993-01-28 1994-08-15 Wellcome Foundation Limited, The Immunoreactive reagents employing heterodimers
US5744120A (en) * 1993-03-30 1998-04-28 The Dupont Merick Pharmaceutical Company Ternary radiopharmaceutical complexes
US5750088A (en) * 1993-03-30 1998-05-12 The Dupont Merck Pharmaceutical Company Stable hydrazones linked to a peptide moiety as reagents for the preparation of radiopharmaceuticals
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
AU7261994A (en) * 1993-07-19 1995-02-20 Resolution Pharmaceuticals Inc. Hydrazino-type radionuclide chelators having an n3s configuration

Also Published As

Publication number Publication date
AU2323197A (en) 1997-10-01
WO1997033627A3 (en) 1998-02-26
EP0888130A2 (de) 1999-01-07
JP2000507233A (ja) 2000-06-13
ES2201284T3 (es) 2004-03-16
CA2249025A1 (en) 1997-09-18
WO1997033627A2 (en) 1997-09-18
EP0888130B1 (de) 2003-07-02
DE69723242T2 (de) 2004-06-03
DE69723242D1 (de) 2003-08-07

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Legal Events

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