ATE244307T1 - Rekombinante proteine des filamentoesen haemaglutinins von bordetella,im besonderen bordetella pertusis, herstellungsverfahren und ihre verwendung zur herstellung von fremdproteinen oder vakzinen - Google Patents

Rekombinante proteine des filamentoesen haemaglutinins von bordetella,im besonderen bordetella pertusis, herstellungsverfahren und ihre verwendung zur herstellung von fremdproteinen oder vakzinen

Info

Publication number: ATE244307T1
Authority: AT; Austria
Prior art keywords: bordetella; fha; sequence; proteins; pertussis
Prior art date: 1994-04-19

Application number

AT95918030T

Other languages

English (en)

Inventor

Camille Locht

Genevieve Renauld

Andre Capron

Gilles Riveau

Franco Menozzi

Francoise Jacob-Dubuisson

Original Assignee

Pasteur Institut

Inst Nat Sante Rech Med

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-04-19

Filing date

1995-04-19

Publication date

2003-07-15

1995-04-19 Application filed by Pasteur Institut, Inst Nat Sante Rech Med filed Critical Pasteur Institut

2003-07-15 Application granted granted Critical

2003-07-15 Publication of ATE244307T1 publication Critical patent/ATE244307T1/de

Links

241000588807 Bordetella Species 0.000 title abstract 5
108090000623 proteins and genes Proteins 0.000 title abstract 4
102000004169 proteins and genes Human genes 0.000 title abstract 4
102000007056 Recombinant Fusion Proteins Human genes 0.000 title 1
108010008281 Recombinant Fusion Proteins Proteins 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
229960005486 vaccine Drugs 0.000 title 1
241000588832 Bordetella pertussis Species 0.000 abstract 3
229920001184 polypeptide Polymers 0.000 abstract 2
102000004196 processed proteins & peptides Human genes 0.000 abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
101710089384 Extracellular protease Proteins 0.000 abstract 1
HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
108020004511 Recombinant DNA Proteins 0.000 abstract 1
210000004027 cell Anatomy 0.000 abstract 1
238000004113 cell culture Methods 0.000 abstract 1
239000006143 cell culture medium Substances 0.000 abstract 1
229960002897 heparin Drugs 0.000 abstract 1
229920000669 heparin Polymers 0.000 abstract 1
230000003993 interaction Effects 0.000 abstract 1
210000004897 n-terminal region Anatomy 0.000 abstract 1
239000002243 precursor Substances 0.000 abstract 1
230000028327 secretion Effects 0.000 abstract 1
238000011144 upstream manufacturing Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)

AT95918030T 1994-04-19 1995-04-19 Rekombinante proteine des filamentoesen haemaglutinins von bordetella,im besonderen bordetella pertusis, herstellungsverfahren und ihre verwendung zur herstellung von fremdproteinen oder vakzinen ATE244307T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9404661A FR2718750B1 (fr)	1994-04-19	1994-04-19	Protéines recombinantes de l'hémagglutinine filamenteuse de Bordetella, notamment, B. Pertussis, production et application à la production de protéines étrangères ou de principes actifs vaccinants.
PCT/FR1995/000512 WO1995028486A2 (fr)	1994-04-19	1995-04-19	Proteines recombinantes de l'hemagglutinine filamenteuse de bordetella, notamment bordetella pertussis, procede pour leur production et leurs applications a la production de proteines etrangeres ou de principes actifs vaccinants

Publications (1)

Publication Number	Publication Date
ATE244307T1 true ATE244307T1 (de)	2003-07-15

Family

ID=9462257

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95918030T ATE244307T1 (de)	1994-04-19	1995-04-19	Rekombinante proteine des filamentoesen haemaglutinins von bordetella,im besonderen bordetella pertusis, herstellungsverfahren und ihre verwendung zur herstellung von fremdproteinen oder vakzinen

Country Status (11)

Country	Link
US (1)	US6841358B1 (de)
EP (1)	EP0755447B1 (de)
AT (1)	ATE244307T1 (de)
AU (1)	AU2412195A (de)
CA (1)	CA2202639C (de)
DE (1)	DE69531200T2 (de)
DK (1)	DK0755447T3 (de)
ES (1)	ES2202363T3 (de)
FR (1)	FR2718750B1 (de)
PT (1)	PT755447E (de)
WO (1)	WO1995028486A2 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5932714A (en) *	1995-02-23	1999-08-03	Connaught Laboratories Limited	Expression of gene products from genetically manipulated strains of Bordetella
FR2754543B1 (fr) *	1996-10-11	1998-12-31	Pasteur Institut	Souche de bordetella deficiente dans la production de toxine et exprimant une proteine hydride, liposomes comprenant de la fha et leurs utilisations comme vaccins, et utilisation de la fha pour stimuler les reponses immunitaires
US7087236B1 (en) *	1998-09-01	2006-08-08	Merrion Research I Limited	Method for inducing a cell-mediated immune response and improved parenteral vaccine formulations thereof
FR2793492A1 (fr) *	1999-05-11	2000-11-17	Pasteur Institut	Nouveau procede de purification par affinite
WO2007104451A1 (en)	2006-03-10	2007-09-20	Institut Pasteur De Lille	Live attenuated bordetella strains as a single dose vaccine against whooping cough
CA2765364C (en)	2009-06-15	2015-05-26	National University Of Singapore	Influenza vaccine, composition, and methods of use
SG10201607233TA (en)	2011-11-02	2016-10-28	Univ Singapore	Effect of an attenuated bordetella strain against allergic disease
EP2722338A1 (de)	2012-10-17	2014-04-23	INSERM (Institut National de la Santé et de la Recherche Médicale)	Neue rekombinante Bordetella-Stämme
WO2014071182A1 (en)	2012-11-01	2014-05-08	Massachusetts Institute Of Technology	Directed evolution of synthetic gene cluster
US9655959B2 (en)	2014-10-01	2017-05-23	National University Of Singapore	Adenylate cyclase deficient bordetella strains
BR112018000729B1 (pt)	2015-07-13	2023-02-07	Pivot Bio, Inc	Método de aumento de uma quantidade de nitrogênio atmosférico em uma planta de milho em um campo
AU2016336328A1 (en)	2015-10-05	2018-04-19	Massachusetts Institute Of Technology	Nitrogen fixation using refactored nif clusters
US10682377B2 (en)	2016-03-29	2020-06-16	Institut Pasteur De Lille	Mutant Bordetella strains and methods of use
AU2018207204B2 (en)	2017-01-12	2023-11-30	Pivot Bio, Inc.	Methods and compositions for improving plant traits
BR112020002654A2 (pt) *	2017-08-09	2020-08-18	Pivot Bio, Inc.	métodos e composições para melhorar micróbios modificados
EP3697439A1 (de)	2017-10-18	2020-08-26	Institut Pasteur de Lille	Bordetella-stämme, die fimbrien des serotyps 3 exprimieren
KR20200087166A (ko)	2017-10-25	2020-07-20	피벗 바이오, 인크.	식물 특성 개선을 위한 질소 고정 표적화용 유전자 표적
CN111587287B (zh)	2017-10-25	2025-02-18	皮沃特生物股份有限公司	用于改良固氮的工程微生物的方法和组合物
BR112020026676A2 (pt)	2018-06-27	2021-08-03	Pivot Bio, Inc.	remodelação microbiana guiada, uma plataforma para a melhoria racional de espécies microbianas para agricultura
CN112739668A (zh)	2018-06-27	2021-04-30	皮沃特生物股份有限公司	包括重构固氮微生物的农业组合物
CN112739202A (zh)	2018-07-11	2021-04-30	皮沃特生物股份有限公司	通过重塑微生物实施时间和空间靶向的动态氮输送
UY38538A (es)	2019-01-07	2020-06-30	Pivot Bio Inc	Ensayos de colonización de plantas con códigos de barras microbianos naturales
WO2020190363A1 (en)	2019-03-19	2020-09-24	Massachusetts Institute Of Technology	Control of nitrogen fixation in rhizobia that associate with cereals
KR20220004047A (ko)	2019-04-25	2022-01-11	피벗 바이오, 인크.	화학적 돌연변이유발에 의해 생성된 암모늄-배출 돌연변이체 라이브러리를 단리하고 특징 분석하기 위한 고 처리량 방법
BR112022021933A2 (pt)	2020-05-01	2022-12-13	Pivot Bio Inc	Composição agrícola líquida, tecido vegetal agrícola, e, métodos para aplicar uma bactéria diazotrófica, manter uma população de uma bactéria, aumentar a produtividade da cultura vegetal agrícola, fornecer nitrogênio atmosférico, aumentar a produtividade do milho por acre, reduzir a variabilidade no campo da produtividade e melhorar a estabilidade de uma composição agrícola líquida
BR112022021723A2 (pt)	2020-05-01	2022-12-06	Pivot Bio Inc	Sistema para cultivo de plantas, métodos para detectar a incorporação de nitrogênio em uma planta e para identificação de uma cepa bacteriana fixadora de nitrogênio, bactéria geneticamente modificada, e, composição
US12643837B2 (en)	2020-05-01	2026-06-02	Pivot Bio, Inc.	Modified bacterial strains for improved fixation of nitrogen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1341123C (en) *	1988-10-27	2000-10-17	David A. Relman	Filamentous hemagglutinin of b. pertussis
US6036960A (en) *	1988-10-27	2000-03-14	Relman; David A.	Filamentous hemagglutinin of B. pertussis
GB9008746D0 (en) *	1990-04-18	1990-06-13	Connaught Lab	The use of autologous promoters to express gene products in bordetella
DE4111531A1 (de) *	1991-04-09	1992-10-29	Biotechnolog Forschung Gmbh	Plasmide zur fha-expression und wirte

1994
- 1994-04-19 FR FR9404661A patent/FR2718750B1/fr not_active Expired - Fee Related
1995
- 1995-04-19 WO PCT/FR1995/000512 patent/WO1995028486A2/fr not_active Ceased
- 1995-04-19 AT AT95918030T patent/ATE244307T1/de active
- 1995-04-19 CA CA002202639A patent/CA2202639C/fr not_active Expired - Fee Related
- 1995-04-19 AU AU24121/95A patent/AU2412195A/en not_active Abandoned
- 1995-04-19 ES ES95918030T patent/ES2202363T3/es not_active Expired - Lifetime
- 1995-04-19 DE DE69531200T patent/DE69531200T2/de not_active Expired - Lifetime
- 1995-04-19 PT PT95918030T patent/PT755447E/pt unknown
- 1995-04-19 EP EP95918030A patent/EP0755447B1/de not_active Expired - Lifetime
- 1995-04-19 DK DK95918030T patent/DK0755447T3/da active
- 1995-04-19 US US08/765,287 patent/US6841358B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US6841358B1 (en)	2005-01-11
DK0755447T3 (da)	2003-10-27
DE69531200T2 (de)	2004-04-15
AU2412195A (en)	1995-11-10
PT755447E (pt)	2003-12-31
CA2202639A1 (fr)	1995-10-26
WO1995028486A2 (fr)	1995-10-26
WO1995028486A3 (fr)	1996-01-11
EP0755447B1 (de)	2003-07-02
FR2718750A1 (fr)	1995-10-20
EP0755447A1 (de)	1997-01-29
CA2202639C (fr)	2004-08-10
ES2202363T3 (es)	2004-04-01
FR2718750B1 (fr)	1996-06-14
DE69531200D1 (de)	2003-08-07

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