ATE244307T1 - Rekombinante proteine des filamentoesen haemaglutinins von bordetella,im besonderen bordetella pertusis, herstellungsverfahren und ihre verwendung zur herstellung von fremdproteinen oder vakzinen - Google Patents

Rekombinante proteine des filamentoesen haemaglutinins von bordetella,im besonderen bordetella pertusis, herstellungsverfahren und ihre verwendung zur herstellung von fremdproteinen oder vakzinen

Info

Publication number: ATE244307T1
Authority: AT; Austria
Prior art keywords: bordetella; fha; sequence; proteins; pertussis
Prior art date: 1994-04-19

Application number

AT95918030T

Other languages

English (en)

Inventor

Camille Locht

Genevieve Renauld

Andre Capron

Gilles Riveau

Franco Menozzi

Francoise Jacob-Dubuisson

Original Assignee

Pasteur Institut

Inst Nat Sante Rech Med

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-04-19

Filing date

1995-04-19

Publication date

2003-07-15

1995-04-19 Application filed by Pasteur Institut, Inst Nat Sante Rech Med filed Critical Pasteur Institut

2003-07-15 Application granted granted Critical

2003-07-15 Publication of ATE244307T1 publication Critical patent/ATE244307T1/de

Links

241000588807 Bordetella Species 0.000 title abstract 5
108090000623 proteins and genes Proteins 0.000 title abstract 4
102000004169 proteins and genes Human genes 0.000 title abstract 4
102000007056 Recombinant Fusion Proteins Human genes 0.000 title 1
108010008281 Recombinant Fusion Proteins Proteins 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
229960005486 vaccine Drugs 0.000 title 1
241000588832 Bordetella pertussis Species 0.000 abstract 3
229920001184 polypeptide Polymers 0.000 abstract 2
102000004196 processed proteins & peptides Human genes 0.000 abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
101710089384 Extracellular protease Proteins 0.000 abstract 1
HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
108020004511 Recombinant DNA Proteins 0.000 abstract 1
210000004027 cell Anatomy 0.000 abstract 1
238000004113 cell culture Methods 0.000 abstract 1
239000006143 cell culture medium Substances 0.000 abstract 1
229960002897 heparin Drugs 0.000 abstract 1
229920000669 heparin Polymers 0.000 abstract 1
230000003993 interaction Effects 0.000 abstract 1
210000004897 n-terminal region Anatomy 0.000 abstract 1
239000002243 precursor Substances 0.000 abstract 1
230000028327 secretion Effects 0.000 abstract 1
238000011144 upstream manufacturing Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)

AT95918030T 1994-04-19 1995-04-19 Rekombinante proteine des filamentoesen haemaglutinins von bordetella,im besonderen bordetella pertusis, herstellungsverfahren und ihre verwendung zur herstellung von fremdproteinen oder vakzinen ATE244307T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9404661A FR2718750B1 (fr)	1994-04-19	1994-04-19	Protéines recombinantes de l'hémagglutinine filamenteuse de Bordetella, notamment, B. Pertussis, production et application à la production de protéines étrangères ou de principes actifs vaccinants.
PCT/FR1995/000512 WO1995028486A2 (fr)	1994-04-19	1995-04-19	Proteines recombinantes de l'hemagglutinine filamenteuse de bordetella, notamment bordetella pertussis, procede pour leur production et leurs applications a la production de proteines etrangeres ou de principes actifs vaccinants

Publications (1)

Publication Number	Publication Date
ATE244307T1 true ATE244307T1 (de)	2003-07-15

Family

ID=9462257

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95918030T ATE244307T1 (de)	1994-04-19	1995-04-19	Rekombinante proteine des filamentoesen haemaglutinins von bordetella,im besonderen bordetella pertusis, herstellungsverfahren und ihre verwendung zur herstellung von fremdproteinen oder vakzinen

Country Status (11)

Country	Link
US (1)	US6841358B1 (de)
EP (1)	EP0755447B1 (de)
AT (1)	ATE244307T1 (de)
AU (1)	AU2412195A (de)
CA (1)	CA2202639C (de)
DE (1)	DE69531200T2 (de)
DK (1)	DK0755447T3 (de)
ES (1)	ES2202363T3 (de)
FR (1)	FR2718750B1 (de)
PT (1)	PT755447E (de)
WO (1)	WO1995028486A2 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5932714A (en) *	1995-02-23	1999-08-03	Connaught Laboratories Limited	Expression of gene products from genetically manipulated strains of Bordetella
FR2754543B1 (fr)	1996-10-11	1998-12-31	Pasteur Institut	Souche de bordetella deficiente dans la production de toxine et exprimant une proteine hydride, liposomes comprenant de la fha et leurs utilisations comme vaccins, et utilisation de la fha pour stimuler les reponses immunitaires
US7087236B1 (en) *	1998-09-01	2006-08-08	Merrion Research I Limited	Method for inducing a cell-mediated immune response and improved parenteral vaccine formulations thereof
FR2793492A1 (fr) *	1999-05-11	2000-11-17	Pasteur Institut	Nouveau procede de purification par affinite
US9119804B2 (en)	2006-03-10	2015-09-01	Institut Pasteur De Lille	Live attenuated bordetella strains as a single dose vaccine against whooping cough
DK2442826T3 (en)	2009-06-15	2015-09-21	Univ Singapore	Influenza vaccine, composition and methods of using
DK2773371T3 (da)	2011-11-02	2020-03-09	Nat Univ Singapore	Virkning af en svækket bordetella-stamme mod allergisk sygdom
EP2722338A1 (de)	2012-10-17	2014-04-23	INSERM (Institut National de la Santé et de la Recherche Médicale)	Neue rekombinante Bordetella-Stämme
WO2014071182A1 (en)	2012-11-01	2014-05-08	Massachusetts Institute Of Technology	Directed evolution of synthetic gene cluster
US9655959B2 (en)	2014-10-01	2017-05-23	National University Of Singapore	Adenylate cyclase deficient bordetella strains
KR102804055B1 (ko)	2015-07-13	2025-05-08	피벗 바이오, 인크.	식물 형질 개선을 위한 방법 및 조성물
CA3001001A1 (en)	2015-10-05	2017-04-13	Massachusetts Institute Of Technology	Nitrogen fixation using refactored nif clusters
EP4541809A3 (de)	2016-03-29	2025-06-25	Institut Pasteur de Lille	Mutierte bordetella-stämme und verfahren zur verwendung
CN116904333A (zh)	2017-01-12	2023-10-20	皮沃特生物公司	用于改良植物性状的方法及组合物
MX2020001599A (es) *	2017-08-09	2020-08-17	Pivot Bio Inc	Métodos y composiciones para mejorar los microbios modificados por ingeniería.
SG11202003333WA (en)	2017-10-18	2020-05-28	Pasteur Institut	Bordetella strains expressing serotype 3 fimbriae
CN111527057A (zh)	2017-10-25	2020-08-11	皮沃特生物股份有限公司	靶向改良植物性状的固氮的基因靶标
MX2020004343A (es)	2017-10-25	2021-01-08	Pivot Bio Inc	Métodos y composiciones para mejorar microbios modificados que fijan nitrógeno.
EP3813511A4 (de)	2018-06-27	2022-08-03	Pivot Bio, Inc.	Geführte mikrobielle remodellierung, plattform zur rationellen verbesserung mikrobieller spezies für die landwirtschaft
WO2020006064A2 (en)	2018-06-27	2020-01-02	Pivot Bio, Inc.	Agricultural compositions comprising remodeled nitrogen fixing microbes
KR20210060434A (ko)	2018-07-11	2021-05-26	피벗 바이오, 인크.	리모델링된 미생물에 의한 시간적 및 공간적 표적화 동적 질소 전달
AU2020206751A1 (en)	2019-01-07	2021-07-01	Pivot Bio, Inc.	Plant colonization assays using natural microbial barcodes
WO2020190363A1 (en)	2019-03-19	2020-09-24	Massachusetts Institute Of Technology	Control of nitrogen fixation in rhizobia that associate with cereals
CA3129539A1 (en)	2019-04-25	2020-10-29	Min-Hyung RYU	High-throughput methods for isolating and characterizing ammonium-excreting mutant libraries generated by chemical mutagenesis
AU2020445067A1 (en)	2020-05-01	2022-12-01	Pivot Bio, Inc.	Measurement of nitrogen fixation and incorporation
CA3172321A1 (en)	2020-05-01	2021-11-04	Farzaneh REZAEI	Stable liquid formulations for nitrogen-fixing microorganisms

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1341123C (en) *	1988-10-27	2000-10-17	David A. Relman	Filamentous hemagglutinin of b. pertussis
US6036960A (en) *	1988-10-27	2000-03-14	Relman; David A.	Filamentous hemagglutinin of B. pertussis
GB9008746D0 (en) *	1990-04-18	1990-06-13	Connaught Lab	The use of autologous promoters to express gene products in bordetella
DE4111531A1 (de) *	1991-04-09	1992-10-29	Biotechnolog Forschung Gmbh	Plasmide zur fha-expression und wirte

1994
- 1994-04-19 FR FR9404661A patent/FR2718750B1/fr not_active Expired - Fee Related
1995
- 1995-04-19 PT PT95918030T patent/PT755447E/pt unknown
- 1995-04-19 CA CA002202639A patent/CA2202639C/fr not_active Expired - Fee Related
- 1995-04-19 AU AU24121/95A patent/AU2412195A/en not_active Abandoned
- 1995-04-19 US US08/765,287 patent/US6841358B1/en not_active Expired - Fee Related
- 1995-04-19 WO PCT/FR1995/000512 patent/WO1995028486A2/fr not_active Ceased
- 1995-04-19 AT AT95918030T patent/ATE244307T1/de active
- 1995-04-19 DK DK95918030T patent/DK0755447T3/da active
- 1995-04-19 DE DE69531200T patent/DE69531200T2/de not_active Expired - Lifetime
- 1995-04-19 ES ES95918030T patent/ES2202363T3/es not_active Expired - Lifetime
- 1995-04-19 EP EP95918030A patent/EP0755447B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2202639A1 (fr)	1995-10-26
PT755447E (pt)	2003-12-31
CA2202639C (fr)	2004-08-10
EP0755447B1 (de)	2003-07-02
EP0755447A1 (de)	1997-01-29
US6841358B1 (en)	2005-01-11
DE69531200D1 (de)	2003-08-07
DK0755447T3 (da)	2003-10-27
ES2202363T3 (es)	2004-04-01
AU2412195A (en)	1995-11-10
FR2718750B1 (fr)	1996-06-14
FR2718750A1 (fr)	1995-10-20
WO1995028486A3 (fr)	1996-01-11
WO1995028486A2 (fr)	1995-10-26
DE69531200T2 (de)	2004-04-15

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