ATE244573T1 - Cyclosporin-enthaltende mikroemulsion- vorkonzentratzusammensetzung - Google Patents

Cyclosporin-enthaltende mikroemulsion- vorkonzentratzusammensetzung

Info

Publication number: ATE244573T1
Authority: AT; Austria
Prior art keywords: microemulsion preconcentrate; containing microemulsion; preconcentrate composition; cyclosporine containing; cyclosporine
Prior art date: 1997-12-05

Application number

AT98947987T

Other languages

English (en)

Inventor

Chung Il Hong

Jung Woo Kim

Nam Hee Choi

Hee Jong Shin

Su Geun Yang

Original Assignee

Chong Kun Dang Pharm Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-12-05

Filing date

1998-10-16

Publication date

2003-07-15

1998-04-29 Priority claimed from KR1019980015309A external-priority patent/KR19990076462A/ko

1998-06-25 Priority claimed from KR1019980024207A external-priority patent/KR19990066706A/ko

1998-10-16 Application filed by Chong Kun Dang Pharm Corp filed Critical Chong Kun Dang Pharm Corp

2003-07-15 Application granted granted Critical

2003-07-15 Publication of ATE244573T1 publication Critical patent/ATE244573T1/de

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
108010036949 Cyclosporine Proteins 0.000 title 1
229960001265 ciclosporin Drugs 0.000 title 1
229930182912 cyclosporin Natural products 0.000 title 1
239000004530 micro-emulsion Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Dispersion Chemistry (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Transplantation (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT98947987T 1997-12-05 1998-10-16 Cyclosporin-enthaltende mikroemulsion- vorkonzentratzusammensetzung ATE244573T1 (de)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
KR19970066454		1997-12-05
KR19980010046		1998-03-24
KR1019980015309A KR19990076462A (ko)	1997-12-05	1998-04-29	사이클로스포린-함유 마이크로에멀젼 예비농축액 조성물
KR1019980024207A KR19990066706A (ko)	1997-03-24	1998-06-25	사이클로스포린-함유 마이크로에멀젼 예비농축액 조성물
PCT/KR1998/000315 WO1999000002A2 (en)	1997-12-05	1998-10-16	Cyclosporin-containing microemulsion preconcentrate composition

Publications (1)

Publication Number	Publication Date
ATE244573T1 true ATE244573T1 (de)	2003-07-15

Family

ID=27483248

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98947987T ATE244573T1 (de)	1997-12-05	1998-10-16	Cyclosporin-enthaltende mikroemulsion- vorkonzentratzusammensetzung

Country Status (15)

Country	Link
US (1)	US6063762A (de)
EP (1)	EP1035862B1 (de)
JP (1)	JP2001517602A (de)
CN (1)	CN1280502A (de)
AR (1)	AR017801A1 (de)
AT (1)	ATE244573T1 (de)
AU (1)	AU9465898A (de)
BR (1)	BR9815350A (de)
CA (1)	CA2313015A1 (de)
DE (1)	DE69816335T2 (de)
HU (1)	HUP0004379A2 (de)
IL (1)	IL136444A0 (de)
NO (1)	NO20002800L (de)
NZ (1)	NZ504844A (de)
WO (1)	WO1999000002A2 (de)

Families Citing this family (40)

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GB9325445D0 (en)	1993-12-13	1994-02-16	Cortecs Ltd	Pharmaceutical formulations
US5858401A (en) *	1996-01-22	1999-01-12	Sidmak Laboratories, Inc.	Pharmaceutical composition for cyclosporines
US6465016B2 (en) *	1996-08-22	2002-10-15	Research Triangle Pharmaceuticals	Cyclosporiine particles
EP0988858A1 (de) *	1997-04-18	2000-03-29	Taisho Pharmaceutical Co., Ltd	Mikroemulsion
WO1999029316A1 (en) *	1997-12-10	1999-06-17	Severson, Mary, L.	Pharmaceutical compositions containing an omega-3 fatty acid oil
GB2380673B (en) *	1998-03-06	2003-05-28	Novartis Ag	Emulsion preconcentrates containing cyclosporin or a macrolide
ID25908A (id) *	1998-03-06	2000-11-09	Novartis Ag	Prakonsentrat-prakonsentrat emulsi yang mengandung siklosporin atau makrolida
US6979456B1 (en)	1998-04-01	2005-12-27	Jagotec Ag	Anticancer compositions
KR100635456B1 (ko)	1998-05-29	2006-10-18	스키에파마 캐나다 인코포레이티드	열보호화 마이크로입자 조성물 및 그의 말단의 스팀멸균방법
DE69912441T2 (de)	1998-08-19	2004-08-19	Skyepharma Canada Inc., Verdun	Injizierbare wässerige propofoldispersionen
IL143197A0 (en)	1998-11-20	2002-04-21	Rtp Pharma Inc	Dispersible phospholipid stabilized microparticles
SE9804192D0 (sv) *	1998-12-03	1998-12-03	Scotia Lipidteknik Ab	New formulation
ATE404172T1 (de)	1998-12-30	2008-08-15	Dexcel Ltd	Dispergierbares konzentrat zur verabreichung von cyclosporin
US6267985B1 (en) *	1999-06-30	2001-07-31	Lipocine Inc.	Clear oil-containing pharmaceutical compositions
GB9912476D0 (en) *	1999-05-28	1999-07-28	Novartis Ag	Organic compounds
NZ515644A (en) *	1999-06-04	2004-12-24	Skyepharma Inc	Oil-core compositions for the sustained release of hydrophobic drugs
GB2355656B (en) *	1999-08-17	2004-04-07	Galena As	Pharmaceutical compositions for oral and topical administration
AU2003254754B2 (en) *	1999-08-17	2006-01-12	Ivax Pharmaceuticals, S.R.O.	Pharmaceutical compositions for oral and topical administration
AU7984200A (en) *	1999-09-21	2001-04-24	Skyepharma Canada Inc.	Surface modified particulate compositions of biologically active substances
WO2001028518A1 (de) *	1999-10-20	2001-04-26	Vesifact Ag	Cyclosporine enthaltende mikroemulsion-prekonzentrate und mikroemulsionen
US7732404B2 (en) *	1999-12-30	2010-06-08	Dexcel Ltd	Pro-nanodispersion for the delivery of cyclosporin
US6623765B1 (en) *	2000-08-01	2003-09-23	University Of Florida, Research Foundation, Incorporated	Microemulsion and micelle systems for solubilizing drugs
JP4391673B2 (ja) *	2000-08-08	2009-12-24	花王株式会社	油脂組成物
EA200301139A1 (ru)	2001-06-21	2004-12-30	Пфайзер Продактс Инк.	Самоэмульгирующиеся препараты ингибиторов белка-переносчика эфиров холестерина
US6960563B2 (en) *	2001-08-31	2005-11-01	Morton Grove Pharmaceuticals, Inc.	Spontaneous emulsions containing cyclosporine
US6479060B1 (en)	2001-09-04	2002-11-12	Healthpoint, Ltd.	Elegant hydrogenated castor oil ointments
IL160761A0 (en) *	2001-10-19	2004-08-31	Isotechnika Inc	Novel cyclosporin analog microemulsion preconcentrates
ITBS20010111A1 (it) *	2001-12-20	2003-06-20	Paoli Ambrosi Gianfranco De	Composizione per uso topico a base dell'estere etilico dell'acido linoleico e e del trietil estere dell'acido citrico associati con opportun
KR100441167B1 (ko) *	2001-12-27	2004-07-21	씨제이 주식회사	마이크로에멀젼 예비 농축액 조성물
US7182950B2 (en) *	2002-06-12	2007-02-27	Nutralease Ltd.	Nano-sized self-assembled liquid dilutable vehicles
DE10226990A1 (de) *	2002-06-18	2004-03-18	Sanguibiotech Ag	Topisch applizierbare Mikro-Emulsionen mit binärer Phasen- und Wirkstoffdifferenzierbarkeit, deren Herstellung und deren Verwendung, insbesondere zur Versorgung der Haut mit bioverfügbarem Sauerstoff
ES2573539T3 (es) *	2005-03-21	2016-06-08	Teva Czech Industries S.R.O.	Inhibidor de la cristalización y su uso en cápsulas de gelatina
CN100478025C (zh) *	2005-03-25	2009-04-15	中国科学院上海药物研究所	一种环孢菌素a眼用微乳制剂及其制备方法
JP4842553B2 (ja) *	2005-03-30	2011-12-21	株式会社ナリス化粧品	ヒドロキシカルボン酸エステルを用いてナノ乳化粒子を安定化させる方法及びナノ乳化粒子を含有する皮膚外用剤
CN101309668A (zh) *	2005-11-30	2008-11-19	健乐克斯医药公司	经口吸收的药物制剂和用药方法
US11311477B2 (en)	2006-03-07	2022-04-26	Sgn Nanopharma Inc.	Ophthalmic preparations
US10137083B2 (en) *	2006-03-07	2018-11-27	SGN Nanopharma Inc	Ophthalmic preparations
EP2001439A2 (de) *	2006-03-07	2008-12-17	Novavax, Inc.	Nanoemulsionen von schlecht löslichen pharmazeutischen aktivbestandteilen und herstellungsverfahren dafür
WO2008058366A1 (en) *	2006-09-28	2008-05-22	Université de Montréal	Oil-in-water emulsions, methods of use thereof, methods of preparation thereof and kits thereof
EP2200613B1 (de)	2007-09-21	2018-09-05	The Johns Hopkins University	Phenazin-derivate und ihre verwendungen

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2907460A1 (de) *	1978-03-07	1979-09-13	Sandoz Ag	Neue resorbierbare galenische kompositionen
US5639724A (en) *	1984-07-24	1997-06-17	Sandoz Ltd.	Cyclosporin galenic forms
KR0148748B1 (ko) *	1988-09-16	1998-08-17	장 크라메르, 한스 루돌프 하우스	사이클로스포린을 함유하는 약학조성물
US5342625A (en) *	1988-09-16	1994-08-30	Sandoz Ltd.	Pharmaceutical compositions comprising cyclosporins
IT1256386B (it) *	1992-11-13	1995-12-04	Luigi Boltri	Composizioni farmaceutiche comprendenti un farmaco,una sostanza polimerica reticolata,un olio ed un agente tensioattivo
US5639474A (en) *	1993-07-01	1997-06-17	Hanmi Pharm. Ind., Ltd.	Cyclosporin soft capsule composition
GB9405304D0 (en) *	1994-03-16	1994-04-27	Scherer Ltd R P	Delivery systems for hydrophobic drugs
HU215966B (hu) *	1994-11-21	1999-07-28	BIOGAL Gyógyszergyár Rt.	Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
EP0760237A1 (de) *	1995-08-30	1997-03-05	Cipla Limited	Öl-in-Wasser-Mikroemulsionen

1998
- 1998-09-03 US US09/146,584 patent/US6063762A/en not_active Expired - Fee Related
- 1998-10-16 CN CN98811777A patent/CN1280502A/zh active Pending
- 1998-10-16 NZ NZ504844A patent/NZ504844A/en unknown
- 1998-10-16 AU AU94658/98A patent/AU9465898A/en not_active Abandoned
- 1998-10-16 EP EP98947987A patent/EP1035862B1/de not_active Expired - Lifetime
- 1998-10-16 IL IL13644498A patent/IL136444A0/xx unknown
- 1998-10-16 JP JP2000500001A patent/JP2001517602A/ja active Pending
- 1998-10-16 DE DE69816335T patent/DE69816335T2/de not_active Expired - Fee Related
- 1998-10-16 AT AT98947987T patent/ATE244573T1/de not_active IP Right Cessation
- 1998-10-16 BR BR9815350-1A patent/BR9815350A/pt not_active IP Right Cessation
- 1998-10-16 WO PCT/KR1998/000315 patent/WO1999000002A2/en not_active Ceased
- 1998-10-16 HU HU0004379A patent/HUP0004379A2/hu unknown
- 1998-10-16 CA CA002313015A patent/CA2313015A1/en not_active Abandoned
- 1998-12-04 AR ARP980106160A patent/AR017801A1/es not_active Application Discontinuation
2000
- 2000-05-31 NO NO20002800A patent/NO20002800L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
JP2001517602A (ja)	2001-10-09
EP1035862A2 (de)	2000-09-20
EP1035862B1 (de)	2003-07-09
NO20002800D0 (no)	2000-05-31
NO20002800L (no)	2000-08-03
HUP0004379A2 (hu)	2001-08-28
NZ504844A (en)	2001-11-30
IL136444A0 (en)	2001-06-14
WO1999000002A2 (en)	1999-01-07
WO1999000002A3 (en)	1999-03-25
BR9815350A (pt)	2001-10-16
AU9465898A (en)	1999-01-19
US6063762A (en)	2000-05-16
DE69816335T2 (de)	2004-04-15
DE69816335D1 (de)	2003-08-14
CA2313015A1 (en)	1999-01-07
AR017801A1 (es)	2001-10-24
CN1280502A (zh)	2001-01-17

Legal Events

Date	Code	Title	Description
2004-01-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE244573T1 (de)	2003-07-15	Cyclosporin-enthaltende mikroemulsion- vorkonzentratzusammensetzung
DK0866117T3 (da)	2004-08-30	Mikroemulsion
FI955042L (fi)	1995-11-29	Syklosporiinia sisältävä jauhemainen koostumus
DK1042359T3 (da)	2005-11-28	k-Opioidreceptorpeptider
FR2769268B1 (fr)	2000-11-10	Siege repliable amovible
DE69839157D1 (de)	2008-04-03	Fullurene enthaltendes katherdersystem
DK0921796T3 (da)	2001-07-16	Tetrahydrolipstatinholdige præparater
PT981375E (pt)	2003-04-30	Composicoes farmaceuticas contendo proteinas do plasma
EP0913191A4 (de)	1999-11-17	Mikroemulsion
DE69836106D1 (de)	2006-11-16	Stanolester enthaltende Zusammensetzungen
ID21315A (id)	1999-05-20	Pancaran gas koheren
PT971702E (pt)	2004-04-30	Microgranulos contendo cis-platina
DE69840500D1 (de)	2009-03-12	Mutierte alpha-amylasen
NO983733D0 (no)	1998-08-14	Ryggsekk
DE19881472D2 (de)	2000-01-13	Gassack
DE69823490D1 (de)	2004-06-03	Antitranspirant präparat
DE59801415D1 (de)	2001-10-18	Gassack
DE59807819D1 (de)	2003-05-15	Duftstoff-enthaltende Zubereitung
DE19882184T1 (de)	2000-02-10	Cyclosporin enthaltende Präparation
DE59813805D1 (de)	2006-12-28	Polsterdüse
KR980000542U (ko)	1998-03-30	정렬대
ZA9810885B (en)	1999-05-27	Cyclosporin-containing microemulsion preconcentrate composition
GB9710933D0 (en)	1997-07-23	Microemulsion compositions
KR980004053U (ko)	1998-03-30	개스통 보관함
ID21077A (id)	1999-04-15	Kursi