ATE244573T1 - Cyclosporin-enthaltende mikroemulsion- vorkonzentratzusammensetzung - Google Patents

Cyclosporin-enthaltende mikroemulsion- vorkonzentratzusammensetzung

Info

Publication number: ATE244573T1
Authority: AT; Austria
Prior art keywords: microemulsion preconcentrate; containing microemulsion; preconcentrate composition; cyclosporine containing; cyclosporine
Prior art date: 1997-12-05

Application number

AT98947987T

Other languages

English (en)

Inventor

Chung Il Hong

Jung Woo Kim

Nam Hee Choi

Hee Jong Shin

Su Geun Yang

Original Assignee

Chong Kun Dang Pharm Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-12-05

Filing date

1998-10-16

Publication date

2003-07-15

1998-04-29 Priority claimed from KR1019980015309A external-priority patent/KR19990076462A/ko

1998-06-25 Priority claimed from KR1019980024207A external-priority patent/KR19990066706A/ko

1998-10-16 Application filed by Chong Kun Dang Pharm Corp filed Critical Chong Kun Dang Pharm Corp

2003-07-15 Application granted granted Critical

2003-07-15 Publication of ATE244573T1 publication Critical patent/ATE244573T1/de

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
108010036949 Cyclosporine Proteins 0.000 title 1
229960001265 ciclosporin Drugs 0.000 title 1
229930182912 cyclosporin Natural products 0.000 title 1
239000004530 micro-emulsion Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Dispersion Chemistry (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Transplantation (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT98947987T 1997-12-05 1998-10-16 Cyclosporin-enthaltende mikroemulsion- vorkonzentratzusammensetzung ATE244573T1 (de)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
KR19970066454		1997-12-05
KR19980010046		1998-03-24
KR1019980015309A KR19990076462A (ko)	1997-12-05	1998-04-29	사이클로스포린-함유 마이크로에멀젼 예비농축액 조성물
KR1019980024207A KR19990066706A (ko)	1997-03-24	1998-06-25	사이클로스포린-함유 마이크로에멀젼 예비농축액 조성물
PCT/KR1998/000315 WO1999000002A2 (en)	1997-12-05	1998-10-16	Cyclosporin-containing microemulsion preconcentrate composition

Publications (1)

Publication Number	Publication Date
ATE244573T1 true ATE244573T1 (de)	2003-07-15

Family

ID=27483248

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98947987T ATE244573T1 (de)	1997-12-05	1998-10-16	Cyclosporin-enthaltende mikroemulsion- vorkonzentratzusammensetzung

Country Status (15)

Country	Link
US (1)	US6063762A (de)
EP (1)	EP1035862B1 (de)
JP (1)	JP2001517602A (de)
CN (1)	CN1280502A (de)
AR (1)	AR017801A1 (de)
AT (1)	ATE244573T1 (de)
AU (1)	AU9465898A (de)
BR (1)	BR9815350A (de)
CA (1)	CA2313015A1 (de)
DE (1)	DE69816335T2 (de)
HU (1)	HUP0004379A2 (de)
IL (1)	IL136444A0 (de)
NO (1)	NO20002800L (de)
NZ (1)	NZ504844A (de)
WO (1)	WO1999000002A2 (de)

Families Citing this family (40)

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GB9325445D0 (en)	1993-12-13	1994-02-16	Cortecs Ltd	Pharmaceutical formulations
US5858401A (en)	1996-01-22	1999-01-12	Sidmak Laboratories, Inc.	Pharmaceutical composition for cyclosporines
US6465016B2 (en) *	1996-08-22	2002-10-15	Research Triangle Pharmaceuticals	Cyclosporiine particles
CN1252711A (zh) *	1997-04-18	2000-05-10	大正制药株式会社	微乳
KR100587551B1 (ko) *	1997-12-10	2006-06-08	싸이클로스포린 테라퓨틱스 리미티드	오메가-3 지방산 오일을 함유하는 약학 조성물
GB2380673B (en) *	1998-03-06	2003-05-28	Novartis Ag	Emulsion preconcentrates containing cyclosporin or a macrolide
ID25908A (id) *	1998-03-06	2000-11-09	Novartis Ag	Prakonsentrat-prakonsentrat emulsi yang mengandung siklosporin atau makrolida
US6979456B1 (en)	1998-04-01	2005-12-27	Jagotec Ag	Anticancer compositions
ES2216517T3 (es)	1998-05-29	2004-10-16	Skyepharma Canada Inc.	Composiciones de microcapsulas termoprotegidas y procedimiento para su esterilizacion terminal con vapor.
EP1105096B1 (de)	1998-08-19	2003-10-29	Skyepharma Canada Inc.	Injizierbare wässerige propofoldispersionen
IL143197A0 (en)	1998-11-20	2002-04-21	Rtp Pharma Inc	Dispersible phospholipid stabilized microparticles
SE9804192D0 (sv) *	1998-12-03	1998-12-03	Scotia Lipidteknik Ab	New formulation
WO2000040219A1 (en)	1998-12-30	2000-07-13	Dexcel Ltd.	Dispersible concentrate for the delivery of cyclosporin
US6267985B1 (en) *	1999-06-30	2001-07-31	Lipocine Inc.	Clear oil-containing pharmaceutical compositions
GB9912476D0 (en) *	1999-05-28	1999-07-28	Novartis Ag	Organic compounds
JP2003501376A (ja) *	1999-06-04	2003-01-14	スカイファーマインコーポレーテッド	疎水性薬物の持続性放出のための油コア組成物
AU2003254754B2 (en) *	1999-08-17	2006-01-12	Ivax Pharmaceuticals, S.R.O.	Pharmaceutical compositions for oral and topical administration
GB2355656B (en) *	1999-08-17	2004-04-07	Galena As	Pharmaceutical compositions for oral and topical administration
DE60020382T2 (de) *	1999-09-21	2006-01-26	Skyepharma Canada Inc., Verdun	Oberflächenmodifizierte teilchenförmige zusammensetzungen biologisch aktiver stoffe
WO2001028518A1 (de) *	1999-10-20	2001-04-26	Vesifact Ag	Cyclosporine enthaltende mikroemulsion-prekonzentrate und mikroemulsionen
US7732404B2 (en) *	1999-12-30	2010-06-08	Dexcel Ltd	Pro-nanodispersion for the delivery of cyclosporin
US6623765B1 (en) *	2000-08-01	2003-09-23	University Of Florida, Research Foundation, Incorporated	Microemulsion and micelle systems for solubilizing drugs
JP4391673B2 (ja) *	2000-08-08	2009-12-24	花王株式会社	油脂組成物
HUP0400263A2 (hu)	2001-06-21	2005-03-29	Pfizer Products Inc.	Koleszteril-észter transzfer protein inhibitort tartalmazó önemulgeáló készítmény
US6960563B2 (en) *	2001-08-31	2005-11-01	Morton Grove Pharmaceuticals, Inc.	Spontaneous emulsions containing cyclosporine
US6479060B1 (en)	2001-09-04	2002-11-12	Healthpoint, Ltd.	Elegant hydrogenated castor oil ointments
PT1435910E (pt) *	2001-10-19	2009-09-07	Isotechnika Inc	Novos pré-concentrados de microemulsão de análogos da ciclosporina
ITBS20010111A1 (it) *	2001-12-20	2003-06-20	Paoli Ambrosi Gianfranco De	Composizione per uso topico a base dell'estere etilico dell'acido linoleico e e del trietil estere dell'acido citrico associati con opportun
KR100441167B1 (ko) *	2001-12-27	2004-07-21	씨제이 주식회사	마이크로에멀젼 예비 농축액 조성물
US7182950B2 (en) *	2002-06-12	2007-02-27	Nutralease Ltd.	Nano-sized self-assembled liquid dilutable vehicles
DE10226990A1 (de) *	2002-06-18	2004-03-18	Sanguibiotech Ag	Topisch applizierbare Mikro-Emulsionen mit binärer Phasen- und Wirkstoffdifferenzierbarkeit, deren Herstellung und deren Verwendung, insbesondere zur Versorgung der Haut mit bioverfügbarem Sauerstoff
WO2006102157A1 (en) *	2005-03-21	2006-09-28	Ivax Pharmaceuticals S.R.O.	Crystallization inhibitor and its use in gelatin capsules
CN100478025C (zh) *	2005-03-25	2009-04-15	中国科学院上海药物研究所	一种环孢菌素a眼用微乳制剂及其制备方法
JP4842553B2 (ja) *	2005-03-30	2011-12-21	株式会社ナリス化粧品	ヒドロキシカルボン酸エステルを用いてナノ乳化粒子を安定化させる方法及びナノ乳化粒子を含有する皮膚外用剤
NZ567601A (en) *	2005-11-30	2010-12-24	Generex Pharm Inc	Orally absorbed pharmaceutical formulation and method of administration
US11311477B2 (en)	2006-03-07	2022-04-26	Sgn Nanopharma Inc.	Ophthalmic preparations
CA2645080A1 (en) *	2006-03-07	2007-09-13	Novavax,Inc.	Nanoemulsions of poorly soluble pharmaceutical active ingredients and methods of making the same
US10137083B2 (en)	2006-03-07	2018-11-27	SGN Nanopharma Inc	Ophthalmic preparations
WO2008058366A1 (en) *	2006-09-28	2008-05-22	Université de Montréal	Oil-in-water emulsions, methods of use thereof, methods of preparation thereof and kits thereof
WO2009042114A2 (en)	2007-09-21	2009-04-02	The Johns Hopkins University	Phenazine derivatives and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI65914C (fi) *	1978-03-07	1984-08-10	Sandoz Ag	Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a
US5639724A (en) *	1984-07-24	1997-06-17	Sandoz Ltd.	Cyclosporin galenic forms
KR0148748B1 (ko) *	1988-09-16	1998-08-17	장 크라메르, 한스 루돌프 하우스	사이클로스포린을 함유하는 약학조성물
US5342625A (en) *	1988-09-16	1994-08-30	Sandoz Ltd.	Pharmaceutical compositions comprising cyclosporins
IT1256386B (it) *	1992-11-13	1995-12-04	Luigi Boltri	Composizioni farmaceutiche comprendenti un farmaco,una sostanza polimerica reticolata,un olio ed un agente tensioattivo
US5639474A (en) *	1993-07-01	1997-06-17	Hanmi Pharm. Ind., Ltd.	Cyclosporin soft capsule composition
GB9405304D0 (en) *	1994-03-16	1994-04-27	Scherer Ltd R P	Delivery systems for hydrophobic drugs
HU215966B (hu) *	1994-11-21	1999-07-28	BIOGAL Gyógyszergyár Rt.	Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
EP0760237A1 (de) *	1995-08-30	1997-03-05	Cipla Limited	Öl-in-Wasser-Mikroemulsionen

1998
- 1998-09-03 US US09/146,584 patent/US6063762A/en not_active Expired - Fee Related
- 1998-10-16 CA CA002313015A patent/CA2313015A1/en not_active Abandoned
- 1998-10-16 AU AU94658/98A patent/AU9465898A/en not_active Abandoned
- 1998-10-16 CN CN98811777A patent/CN1280502A/zh active Pending
- 1998-10-16 EP EP98947987A patent/EP1035862B1/de not_active Expired - Lifetime
- 1998-10-16 NZ NZ504844A patent/NZ504844A/en unknown
- 1998-10-16 WO PCT/KR1998/000315 patent/WO1999000002A2/en not_active Ceased
- 1998-10-16 IL IL13644498A patent/IL136444A0/xx unknown
- 1998-10-16 JP JP2000500001A patent/JP2001517602A/ja active Pending
- 1998-10-16 HU HU0004379A patent/HUP0004379A2/hu unknown
- 1998-10-16 AT AT98947987T patent/ATE244573T1/de not_active IP Right Cessation
- 1998-10-16 DE DE69816335T patent/DE69816335T2/de not_active Expired - Fee Related
- 1998-10-16 BR BR9815350-1A patent/BR9815350A/pt not_active IP Right Cessation
- 1998-12-04 AR ARP980106160A patent/AR017801A1/es not_active Application Discontinuation
2000
- 2000-05-31 NO NO20002800A patent/NO20002800L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO1999000002A3 (en)	1999-03-25
HUP0004379A2 (hu)	2001-08-28
JP2001517602A (ja)	2001-10-09
DE69816335T2 (de)	2004-04-15
BR9815350A (pt)	2001-10-16
AR017801A1 (es)	2001-10-24
WO1999000002A2 (en)	1999-01-07
CA2313015A1 (en)	1999-01-07
US6063762A (en)	2000-05-16
NZ504844A (en)	2001-11-30
NO20002800L (no)	2000-08-03
CN1280502A (zh)	2001-01-17
EP1035862A2 (de)	2000-09-20
AU9465898A (en)	1999-01-19
DE69816335D1 (de)	2003-08-14
NO20002800D0 (no)	2000-05-31
IL136444A0 (en)	2001-06-14
EP1035862B1 (de)	2003-07-09

Legal Events

Date	Code	Title	Description
2004-01-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE244573T1 (de)	2003-07-15	Cyclosporin-enthaltende mikroemulsion- vorkonzentratzusammensetzung
DK0866117T3 (da)	2004-08-30	Mikroemulsion
FI955042A0 (fi)	1995-10-23	Syklosporiinia sisältävä jauhemainen koostumus
DK1042359T3 (da)	2005-11-28	k-Opioidreceptorpeptider
FR2769268B1 (fr)	2000-11-10	Siege repliable amovible
DE69607178D1 (de)	2000-04-20	Mikroemulsionsförmige Desinfektionszusammensetzung
DE69832516D1 (de)	2005-12-29	Isoflavon-enthaltende zusammensetzungen
PT981375E (pt)	2003-04-30	Composicoes farmaceuticas contendo proteinas do plasma
DE69800639D1 (de)	2001-05-03	Tetrahydrolipstatin enthaltende präparate
DE69836106D1 (de)	2006-11-16	Stanolester enthaltende Zusammensetzungen
EP0913191A4 (de)	1999-11-17	Mikroemulsion
ID21315A (id)	1999-05-20	Pancaran gas koheren
PT971702E (pt)	2004-04-30	Microgranulos contendo cis-platina
DE59805824D1 (de)	2002-11-07	Anzünder
DE59806582D1 (de)	2003-01-23	Sitzmöbel
NO983733D0 (no)	1998-08-14	Ryggsekk
DE59807819D1 (de)	2003-05-15	Duftstoff-enthaltende Zubereitung
DE59813805D1 (de)	2006-12-28	Polsterdüse
KR980000542U (ko)	1998-03-30	정렬대
ZA9810885B (en)	1999-05-27	Cyclosporin-containing microemulsion preconcentrate composition
GB9710933D0 (en)	1997-07-23	Microemulsion compositions
DE59810338D1 (de)	2004-01-15	Gassack
KR980004053U (ko)	1998-03-30	개스통 보관함
ID21077A (id)	1999-04-15	Kursi
IT1296674B1 (it)	1999-07-14	Amaca meccanica