ATE245029T1 - Verwendung von methoxymorpholino doxorubicin zur behandlung eines lebertumor - Google Patents

Verwendung von methoxymorpholino doxorubicin zur behandlung eines lebertumor

Info

Publication number: ATE245029T1
Authority: AT; Austria
Prior art keywords: liver tumor; treat; methoxymorpholino doxorubicin; methoxymorpholino; doxorubicin
Prior art date: 1998-09-14

Application number

AT99944533T

Other languages

English (en)

Inventor

Maria Adele Pacciarini

Olga Valota

David Kerr

Original Assignee

Pharmacia Italia Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-09-14

Filing date

1999-08-27

Publication date

2003-08-15

1999-08-27 Application filed by Pharmacia Italia Spa filed Critical Pharmacia Italia Spa

2003-08-15 Application granted granted Critical

2003-08-15 Publication of ATE245029T1 publication Critical patent/ATE245029T1/de

Links

208000014018 liver neoplasm Diseases 0.000 title abstract 4
206010019695 Hepatic neoplasm Diseases 0.000 title abstract 3
CTMCWCONSULRHO-UHQPFXKFSA-N nemorubicin Chemical compound C1CO[C@H](OC)CN1[C@@H]1[C@H](O)[C@H](C)O[C@@H](O[C@@H]2C3=C(O)C=4C(=O)C5=C(OC)C=CC=C5C(=O)C=4C(O)=C3C[C@](O)(C2)C(=O)CO)C1 CTMCWCONSULRHO-UHQPFXKFSA-N 0.000 title abstract 3
239000003795 chemical substances by application Substances 0.000 abstract 1
210000002767 hepatic artery Anatomy 0.000 abstract 1
238000002347 injection Methods 0.000 abstract 1
239000007924 injection Substances 0.000 abstract 1
201000007270 liver cancer Diseases 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5355—Non-condensed oxazines and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Gastroenterology & Hepatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Oncology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT99944533T 1998-09-14 1999-08-27 Verwendung von methoxymorpholino doxorubicin zur behandlung eines lebertumor ATE245029T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9820012.4A GB9820012D0 (en)	1998-09-14	1998-09-14	Use of an anthracycline derivative for the treatment of a liver tumor
PCT/EP1999/006298 WO2000015203A2 (en)	1998-09-14	1999-08-27	Use of methoxymorpholino doxorubicin for the treatment of a liver tumor

Publications (1)

Publication Number	Publication Date
ATE245029T1 true ATE245029T1 (de)	2003-08-15

Family

ID=10838847

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99944533T ATE245029T1 (de)	1998-09-14	1999-08-27	Verwendung von methoxymorpholino doxorubicin zur behandlung eines lebertumor

Country Status (25)

Country	Link
EP (1)	EP1112066B1 (de)
JP (2)	JP5529360B2 (de)
KR (1)	KR100685155B1 (de)
CN (1)	CN1168452C (de)
AT (1)	ATE245029T1 (de)
AU (1)	AU773451B2 (de)
BR (1)	BR9913627A (de)
CA (1)	CA2343120C (de)
CZ (1)	CZ295901B6 (de)
DE (1)	DE69909636T2 (de)
DK (1)	DK1112066T3 (de)
EA (1)	EA004570B1 (de)
ES (1)	ES2203175T3 (de)
GB (1)	GB9820012D0 (de)
HU (1)	HU229186B1 (de)
ID (1)	ID28035A (de)
IL (2)	IL141645A0 (de)
MY (1)	MY124247A (de)
NO (1)	NO329746B1 (de)
NZ (1)	NZ510445A (de)
PL (1)	PL198025B1 (de)
PT (1)	PT1112066E (de)
TW (1)	TWI222868B (de)
UA (1)	UA69423C2 (de)
WO (1)	WO2000015203A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9909925D0 (en)	1999-04-29	1999-06-30	Pharmacia & Upjohn Spa	Combined preparations comprising anthracycline derivatives
WO2004038404A2 (en) *	2002-10-28	2004-05-06	Pharmacia Italia Spa	Method for optimizing therapeutic efficacy of nemorubicin
US20060264388A1 (en) *	2003-02-26	2006-11-23	Olga Valota	Method for treating liver cancer by intrahepatic administration of nemorubicin
JP5302300B2 (ja) *	2007-05-11	2013-10-02	ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ	アンスラサイクリンの医薬組成物
JP2016124818A (ja) *	2014-12-26	2016-07-11	日本化薬株式会社	転移性肝癌治療薬及び転移性肝癌の治療方法
PL244818B1 (pl) *	2021-11-03	2024-03-11	Urteste Spolka Z Ograniczona Odpowiedzialnoscia	Związek-marker diagnostyczny raka wątroby, sposób wykrywania aktywności enzymatycznej, sposób diagnozowania raka wątroby, zestaw zawierający taki związek oraz związek do zastosowania medycznego

1998
- 1998-09-14 GB GBGB9820012.4A patent/GB9820012D0/en not_active Ceased
1999
- 1999-08-27 CN CNB998109118A patent/CN1168452C/zh not_active Expired - Fee Related
- 1999-08-27 EA EA200100353A patent/EA004570B1/ru not_active IP Right Cessation
- 1999-08-27 DK DK99944533T patent/DK1112066T3/da active
- 1999-08-27 KR KR1020017003222A patent/KR100685155B1/ko not_active Expired - Fee Related
- 1999-08-27 ID IDW20010805A patent/ID28035A/id unknown
- 1999-08-27 PL PL348749A patent/PL198025B1/pl unknown
- 1999-08-27 UA UA2001042524A patent/UA69423C2/uk unknown
- 1999-08-27 HU HU0103557A patent/HU229186B1/hu not_active IP Right Cessation
- 1999-08-27 PT PT99944533T patent/PT1112066E/pt unknown
- 1999-08-27 AT AT99944533T patent/ATE245029T1/de active
- 1999-08-27 WO PCT/EP1999/006298 patent/WO2000015203A2/en not_active Ceased
- 1999-08-27 AU AU57421/99A patent/AU773451B2/en not_active Ceased
- 1999-08-27 NZ NZ510445A patent/NZ510445A/xx not_active IP Right Cessation
- 1999-08-27 DE DE69909636T patent/DE69909636T2/de not_active Expired - Lifetime
- 1999-08-27 CZ CZ2001895A patent/CZ295901B6/cs not_active IP Right Cessation
- 1999-08-27 BR BR9913627-9A patent/BR9913627A/pt not_active Application Discontinuation
- 1999-08-27 IL IL14164599A patent/IL141645A0/xx active IP Right Grant
- 1999-08-27 JP JP2000569787A patent/JP5529360B2/ja not_active Expired - Fee Related
- 1999-08-27 EP EP99944533A patent/EP1112066B1/de not_active Expired - Lifetime
- 1999-08-27 ES ES99944533T patent/ES2203175T3/es not_active Expired - Lifetime
- 1999-08-27 CA CA002343120A patent/CA2343120C/en not_active Expired - Fee Related
- 1999-09-03 TW TW088115180A patent/TWI222868B/zh not_active IP Right Cessation
- 1999-09-10 MY MYPI99003920A patent/MY124247A/en unknown
2001
- 2001-02-26 IL IL141645A patent/IL141645A/en not_active IP Right Cessation
- 2001-03-05 NO NO20011116A patent/NO329746B1/no not_active IP Right Cessation
2013
- 2013-12-10 JP JP2013255003A patent/JP2014088398A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
WO2000015203A3 (en)	2000-07-20
CZ295901B6 (cs)	2005-11-16
BR9913627A (pt)	2001-05-22
GB9820012D0 (en)	1998-11-04
IL141645A (en)	2007-05-15
NO329746B1 (no)	2010-12-13
WO2000015203A2 (en)	2000-03-23
MY124247A (en)	2006-06-30
PL348749A1 (en)	2002-06-03
EP1112066B1 (de)	2003-07-16
HK1050853A1 (en)	2003-07-11
IL141645A0 (en)	2002-03-10
JP2014088398A (ja)	2014-05-15
UA69423C2 (uk)	2004-09-15
DE69909636T2 (de)	2004-06-09
ID28035A (id)	2001-05-03
CA2343120C (en)	2009-11-24
HUP0103557A3 (en)	2002-12-28
EA200100353A1 (ru)	2001-10-22
HU229186B1 (en)	2013-09-30
JP2002524496A (ja)	2002-08-06
JP5529360B2 (ja)	2014-06-25
AU5742199A (en)	2000-04-03
ES2203175T3 (es)	2004-04-01
PT1112066E (pt)	2003-11-28
EP1112066A2 (de)	2001-07-04
NO20011116L (no)	2001-05-14
CN1383382A (zh)	2002-12-04
PL198025B1 (pl)	2008-05-30
HUP0103557A2 (hu)	2002-01-28
KR100685155B1 (ko)	2007-02-22
NZ510445A (en)	2003-01-31
DK1112066T3 (da)	2003-11-03
DE69909636D1 (de)	2003-08-21
EA004570B1 (ru)	2004-06-24
CA2343120A1 (en)	2000-03-23
TWI222868B (en)	2004-11-01
AU773451B2 (en)	2004-05-27
KR20010075074A (ko)	2001-08-09
NO20011116D0 (no)	2001-03-05
CN1168452C (zh)	2004-09-29
CZ2001895A3 (cs)	2001-08-15

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