ATE246179T1 - Verfahren zur herstellung von n-carboxy-t-leucin anhydrid - Google Patents
Verfahren zur herstellung von n-carboxy-t-leucin anhydridInfo
- Publication number
- ATE246179T1 ATE246179T1 AT01201586T AT01201586T ATE246179T1 AT E246179 T1 ATE246179 T1 AT E246179T1 AT 01201586 T AT01201586 T AT 01201586T AT 01201586 T AT01201586 T AT 01201586T AT E246179 T1 ATE246179 T1 AT E246179T1
- Authority
- AT
- Austria
- Prior art keywords
- carboxy
- leucine
- producing
- amine
- anhydride
- Prior art date
Links
- KKSBRHLIZWGGTR-HTQZYQBOSA-N OC(=O)N[C@@H](C(C)(C)C)C(=O)OC(=O)[C@@H](NC(O)=O)C(C)(C)C Chemical compound OC(=O)N[C@@H](C(C)(C)C)C(=O)OC(=O)[C@@H](NC(O)=O)C(C)(C)C KKSBRHLIZWGGTR-HTQZYQBOSA-N 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- BAVYZALUXZFZLV-UHFFFAOYSA-N Methylamine Chemical compound NC BAVYZALUXZFZLV-UHFFFAOYSA-N 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- AWECGHXJUXCNBT-SCSAIBSYSA-N (2s)-2-(carboxyamino)-3,3-dimethylbutanoic acid Chemical compound CC(C)(C)[C@@H](C(O)=O)NC(O)=O AWECGHXJUXCNBT-SCSAIBSYSA-N 0.000 abstract 1
- WETWJCDKMRHUPV-UHFFFAOYSA-N acetyl chloride Chemical compound CC(Cl)=O WETWJCDKMRHUPV-UHFFFAOYSA-N 0.000 abstract 1
- 239000012346 acetyl chloride Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- -1 t-leucine-N-substituted amide Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/44—Two oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL1015169A NL1015169C2 (nl) | 2000-05-12 | 2000-05-12 | Werkwijze voor de bereiding van N-carboxy-t-leucineanhydride. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE246179T1 true ATE246179T1 (de) | 2003-08-15 |
Family
ID=19771361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01201586T ATE246179T1 (de) | 2000-05-12 | 2001-05-02 | Verfahren zur herstellung von n-carboxy-t-leucin anhydrid |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6476231B2 (de) |
| EP (1) | EP1153923B1 (de) |
| JP (1) | JP2002003482A (de) |
| AT (1) | ATE246179T1 (de) |
| DE (1) | DE60100523T2 (de) |
| ES (1) | ES2202255T3 (de) |
| NL (1) | NL1015169C2 (de) |
| PT (1) | PT1153923E (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3118035A1 (fr) * | 2020-12-23 | 2022-06-24 | Centre National De La Recherche Scientifique | Nouveau procédé de synthèse de composés NCAs |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1038913A (en) * | 1962-11-16 | 1966-08-10 | Asahi Chemical Ind | A process for producing n-carboxy anhydrides of alpha-amino acids |
-
2000
- 2000-05-12 NL NL1015169A patent/NL1015169C2/nl not_active IP Right Cessation
-
2001
- 2001-05-02 AT AT01201586T patent/ATE246179T1/de active
- 2001-05-02 EP EP01201586A patent/EP1153923B1/de not_active Expired - Lifetime
- 2001-05-02 ES ES01201586T patent/ES2202255T3/es not_active Expired - Lifetime
- 2001-05-02 PT PT01201586T patent/PT1153923E/pt unknown
- 2001-05-02 DE DE60100523T patent/DE60100523T2/de not_active Expired - Lifetime
- 2001-05-10 JP JP2001140389A patent/JP2002003482A/ja not_active Withdrawn
- 2001-05-11 US US09/852,849 patent/US6476231B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE60100523D1 (de) | 2003-09-04 |
| DE60100523T2 (de) | 2004-06-09 |
| NL1015169C2 (nl) | 2001-11-13 |
| ES2202255T3 (es) | 2004-04-01 |
| EP1153923A1 (de) | 2001-11-14 |
| US6476231B2 (en) | 2002-11-05 |
| JP2002003482A (ja) | 2002-01-09 |
| US20010041812A1 (en) | 2001-11-15 |
| EP1153923B1 (de) | 2003-07-30 |
| PT1153923E (pt) | 2003-11-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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