ATE246339T1 - Messen von intermolekularen wechselwirkungen mit einem rasterkraftmikroskop - Google Patents

Messen von intermolekularen wechselwirkungen mit einem rasterkraftmikroskop

Info

Publication number
ATE246339T1
ATE246339T1 AT99922782T AT99922782T ATE246339T1 AT E246339 T1 ATE246339 T1 AT E246339T1 AT 99922782 T AT99922782 T AT 99922782T AT 99922782 T AT99922782 T AT 99922782T AT E246339 T1 ATE246339 T1 AT E246339T1
Authority
AT
Austria
Prior art keywords
compound
sample
support member
reference compound
atomic force
Prior art date
Application number
AT99922782T
Other languages
English (en)
Inventor
Green John-Bruce Devault
Gil U Lee
Original Assignee
Us Gov Sec Navy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Sec Navy filed Critical Us Gov Sec Navy
Application granted granted Critical
Publication of ATE246339T1 publication Critical patent/ATE246339T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B11/00—Measuring arrangements characterised by the use of optical techniques
    • G01B11/24—Measuring arrangements characterised by the use of optical techniques for measuring contours or curvatures
    • G01B11/255—Measuring arrangements characterised by the use of optical techniques for measuring contours or curvatures for measuring radius of curvature
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01Q—SCANNING-PROBE TECHNIQUES OR APPARATUS; APPLICATIONS OF SCANNING-PROBE TECHNIQUES, e.g. SCANNING PROBE MICROSCOPY [SPM]
    • G01Q60/00—Particular types of SPM [Scanning Probe Microscopy] or microscopes; Essential components thereof
    • G01Q60/24—AFM [Atomic Force Microscopy] or apparatus therefor, e.g. AFM probes
    • G01Q60/38—Probes, their manufacture, or their related instrumentation, e.g. holders
    • G01Q60/42—Functionalisation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y35/00—Methods or apparatus for measurement or analysis of nanostructures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/849—Manufacture, treatment, or detection of nanostructure with scanning probe
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/849—Manufacture, treatment, or detection of nanostructure with scanning probe
    • Y10S977/85—Scanning probe control process
    • Y10S977/851—Particular movement or positioning of scanning tip
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/849—Manufacture, treatment, or detection of nanostructure with scanning probe
    • Y10S977/852—Manufacture, treatment, or detection of nanostructure with scanning probe for detection of specific nanostructure sample or nanostructure-related property
    • Y10S977/853—Biological sample
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/849—Manufacture, treatment, or detection of nanostructure with scanning probe
    • Y10S977/86—Scanning probe structure
    • Y10S977/863—Atomic force probe

Landscapes

  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Length Measuring Devices With Unspecified Measuring Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Length Measuring Devices By Optical Means (AREA)
AT99922782T 1998-05-08 1999-05-05 Messen von intermolekularen wechselwirkungen mit einem rasterkraftmikroskop ATE246339T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/074,541 US5992226A (en) 1998-05-08 1998-05-08 Apparatus and method for measuring intermolecular interactions by atomic force microscopy
PCT/US1999/009696 WO1999058922A1 (en) 1998-05-08 1999-05-05 Apparatus and method for measuring intermolecular interactions by atomic force microscopy

Publications (1)

Publication Number Publication Date
ATE246339T1 true ATE246339T1 (de) 2003-08-15

Family

ID=22120112

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99922782T ATE246339T1 (de) 1998-05-08 1999-05-05 Messen von intermolekularen wechselwirkungen mit einem rasterkraftmikroskop

Country Status (10)

Country Link
US (1) US5992226A (de)
EP (1) EP1076803B1 (de)
JP (1) JP2003505665A (de)
KR (1) KR100642836B1 (de)
AT (1) ATE246339T1 (de)
AU (1) AU752634B2 (de)
CA (1) CA2331585C (de)
DE (1) DE69910001T2 (de)
MX (1) MXPA00010904A (de)
WO (1) WO1999058922A1 (de)

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US20020042081A1 (en) * 2000-10-10 2002-04-11 Eric Henderson Evaluating binding affinities by force stratification and force panning
US6573369B2 (en) * 1999-05-21 2003-06-03 Bioforce Nanosciences, Inc. Method and apparatus for solid state molecular analysis
US20030186311A1 (en) * 1999-05-21 2003-10-02 Bioforce Nanosciences, Inc. Parallel analysis of molecular interactions
US6897015B2 (en) * 2000-03-07 2005-05-24 Bioforce Nanosciences, Inc. Device and method of use for detection and characterization of pathogens and biological materials
US20040253627A1 (en) * 2000-07-07 2004-12-16 Grant Zimmermann System and method for multidimensional evaluation of combinations of compositions
US20020019011A1 (en) * 2000-07-07 2002-02-14 Stockwell Brent R. Methods for identifying combinations of entities as therapeutics
CA2417939A1 (en) * 2000-08-09 2002-02-14 California Institute Of Technology Active nems arrays for biochemical analyses
DE10051143C2 (de) * 2000-08-11 2002-07-11 Nanotype Gmbh Verfahren und Vorrichtung zur Charakterisierung und/oder zum Nachweis eines Bindungskomplexes
DE10117866A1 (de) * 2001-04-10 2002-10-17 Nanotype Gmbh Verfahren und Vorrichtung zur Charakterisierung und/oder zum Nachweis eines Bindungskomplexes
CA2418861A1 (en) * 2000-08-11 2002-02-21 Nanotype Gmbh Method and device for characterising and/or for detecting a bonding complex
CN1261745C (zh) * 2000-08-15 2006-06-28 拜澳富斯毫微科学有限公司 纳米级分子阵列排布机
DE10126798A1 (de) * 2001-06-01 2002-12-19 Nanotype Gmbh Verfahren zur Bestimmung einer Probe
US6813958B2 (en) 2001-06-21 2004-11-09 The United States Of America As Represented By The Secretary Of Commerce Method for combinatorially measuring adhesion strength
WO2003008941A2 (en) * 2001-07-17 2003-01-30 Bioforce Nanosciences, Inc. Combined molecular blinding detection through force microscopy and mass spectrometry
TW573125B (en) * 2001-08-29 2004-01-21 Combinatorx Inc A screening system for identifying drug-drug interactions and methods of use thereof
US20030068655A1 (en) * 2001-09-12 2003-04-10 Protiveris, Inc. Microcantilever apparatus and methods for detection of enzymes
US7042488B2 (en) 2001-09-27 2006-05-09 Fujinon Corporation Electronic endoscope for highlighting blood vessel
US6926864B2 (en) * 2001-11-09 2005-08-09 Protiveris Inc Microfluidics apparatus and methods for use thereof
SE0103781D0 (sv) * 2001-11-12 2001-11-12 Nanofactory Instruments Ab Mätanordning för elektronmikroskop
US20050239193A1 (en) * 2002-05-30 2005-10-27 Bioforce Nanosciences, Inc. Device and method of use for detection and characterization of microorganisms and microparticles
US6612161B1 (en) * 2002-07-23 2003-09-02 Fidelica Microsystems, Inc. Atomic force microscopy measurements of contact resistance and current-dependent stiction
KR20050100367A (ko) * 2003-01-02 2005-10-18 바이오포스 나노사이언스, 인크. 소용적 샘플 내의 분자 분석용 방법 및 장치
US6943417B2 (en) * 2003-05-01 2005-09-13 Clemson University DNA-based memory device and method of reading and writing same
US7055378B2 (en) * 2003-08-11 2006-06-06 Veeco Instruments, Inc. System for wide frequency dynamic nanomechanical analysis
US6812460B1 (en) * 2003-10-07 2004-11-02 Zyvex Corporation Nano-manipulation by gyration
JP2006343285A (ja) * 2005-06-10 2006-12-21 Olympus Corp 走査型プローブ顕微鏡用の試料台配列
US7647848B2 (en) * 2005-11-29 2010-01-19 Drexel University Integrated system for simultaneous inspection and manipulation
EP2013609A2 (de) * 2005-12-31 2009-01-14 Carbon Nanoprobes, Inc. Rasterkraftmikroskop-spitzen-arrays und verfahren zur herstellung davon
US20070186629A1 (en) * 2006-02-10 2007-08-16 Ying-Lan Chang Functionalizable nanowire-based AFM probe
US7965614B2 (en) * 2007-02-01 2011-06-21 Seagate Technology Llc Wear resistant data storage device
WO2013006405A1 (en) * 2011-07-01 2013-01-10 Ohio University Dynamic biochemical tissue analysis assays and compositions
TWI474004B (zh) * 2012-07-13 2015-02-21 Nat Univ Tsing Hua 多頭探針及其製造與掃瞄方法
CN103676127B (zh) * 2013-12-31 2015-03-11 爱威科技股份有限公司 用于显微镜的支撑装置、显微镜及显微镜载物台
CA2976043A1 (en) 2015-02-10 2016-10-06 Multerra Bio, Inc. Apparatuses and methods for detecting molecules and binding energy
US9816988B1 (en) 2016-08-10 2017-11-14 Multerra Bio, Inc. Apparatuses and methods for detecting molecules and binding energy
US10444179B2 (en) 2016-08-10 2019-10-15 Multerra Bio, Inc. Apparatuses and methods for detecting molecules and binding energy
EP3431982A1 (de) 2017-07-18 2019-01-23 Nanosurf AG Mikroausleger
EP3809143B1 (de) 2019-10-17 2023-07-19 Imec VZW Verfahren für rastersondenmikroskopie

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Also Published As

Publication number Publication date
DE69910001T2 (de) 2004-04-15
DE69910001D1 (de) 2003-09-04
AU752634B2 (en) 2002-09-26
WO1999058922A1 (en) 1999-11-18
EP1076803A1 (de) 2001-02-21
KR100642836B1 (ko) 2006-11-03
MXPA00010904A (es) 2002-05-08
EP1076803A4 (de) 2001-07-25
JP2003505665A (ja) 2003-02-12
EP1076803B1 (de) 2003-07-30
CA2331585A1 (en) 1999-11-18
US5992226A (en) 1999-11-30
KR20010071224A (ko) 2001-07-28
CA2331585C (en) 2008-12-09
AU3970199A (en) 1999-11-29

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