ATE247456T1 - Puderförmige zusammensetzung zur nasalen anwendung - Google Patents

Puderförmige zusammensetzung zur nasalen anwendung

Info

Publication number
ATE247456T1
ATE247456T1 AT97905398T AT97905398T ATE247456T1 AT E247456 T1 ATE247456 T1 AT E247456T1 AT 97905398 T AT97905398 T AT 97905398T AT 97905398 T AT97905398 T AT 97905398T AT E247456 T1 ATE247456 T1 AT E247456T1
Authority
AT
Austria
Prior art keywords
water
absorbing
base material
drug
gel
Prior art date
Application number
AT97905398T
Other languages
English (en)
Inventor
Masahiko Dohi
Yoshihisa Nishibe
Yuji Makino
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26378964&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE247456(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teijin Ltd filed Critical Teijin Ltd
Application granted granted Critical
Publication of ATE247456T1 publication Critical patent/ATE247456T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT97905398T 1996-02-27 1997-02-26 Puderförmige zusammensetzung zur nasalen anwendung ATE247456T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP3955396 1996-02-27
JP4107996 1996-02-28
PCT/JP1997/000541 WO1997031626A1 (en) 1996-02-27 1997-02-26 Powdery composition for nasal administration

Publications (1)

Publication Number Publication Date
ATE247456T1 true ATE247456T1 (de) 2003-09-15

Family

ID=26378964

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97905398T ATE247456T1 (de) 1996-02-27 1997-02-26 Puderförmige zusammensetzung zur nasalen anwendung

Country Status (13)

Country Link
US (3) US6881423B2 (de)
EP (1) EP0943326B2 (de)
JP (1) JP3634380B2 (de)
KR (1) KR100568436B1 (de)
CN (1) CN1155368C (de)
AT (1) ATE247456T1 (de)
AU (1) AU722319B2 (de)
CA (1) CA2247191C (de)
DE (1) DE69724272T3 (de)
DK (1) DK0943326T4 (de)
ES (1) ES2205177T5 (de)
PT (1) PT943326E (de)
WO (1) WO1997031626A1 (de)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6881423B2 (en) * 1996-02-27 2005-04-19 Teijin Limited Powdery composition for nasal administration
TWI243687B (en) 1998-04-21 2005-11-21 Teijin Ltd Pharmaceutical composition for application to mucosa
KR100611025B1 (ko) * 1998-08-26 2006-08-10 데이진 가부시키가이샤 분말상 경비 조성물
JP2002531489A (ja) * 1998-12-09 2002-09-24 カイロン コーポレイション 中枢神経系への神経栄養剤の投与
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
AR026073A1 (es) 1999-10-20 2002-12-26 Nycomed Gmbh Composicion farmaceutica acuosa que contiene ciclesonida
ATE420630T1 (de) * 2000-11-29 2009-01-15 Itoham Foods Inc Pulverzubereitungen und verfahren zu ihrer herstellung
GB2378383A (en) * 2001-06-06 2003-02-12 Gursharan Moonga Nasal delivery of pharmaceutical compositions in powder form
US6906027B2 (en) 2001-07-05 2005-06-14 Translational Research Ltd. Composition for nasal administration of insulin
US20050014681A1 (en) * 2001-11-26 2005-01-20 Yoshiharu Minamitake Medicinal compositions for nasal absorption
ATE385193T1 (de) 2002-03-20 2008-02-15 Mannkind Corp Inhalationsgerät
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
US20080260838A1 (en) * 2003-08-01 2008-10-23 Mannkind Corporation Glucagon-like peptide 1 (glp-1) pharmaceutical formulations
AU2003272517A1 (en) * 2002-09-13 2004-04-30 Zicam, Llc. Compositions to reduce congestion and methods for application thereof to the nasal membrane
WO2004073729A1 (ja) 2003-02-21 2004-09-02 Translational Research Ltd. 薬物の経鼻投与用組成物
US7812120B2 (en) 2003-03-21 2010-10-12 Par Pharmaceutical, Inc. Nasal calcitonin formulations containing chlorobutanol
US7278982B2 (en) 2003-03-27 2007-10-09 Bioactis Limited Powder medicine applicator for nasal cavity
GB0315632D0 (en) 2003-07-04 2003-08-13 West Pharm Serv Drug Res Ltd Pharmaceutical formulations
EP1785145A4 (de) * 2004-08-10 2008-08-13 Translational Res Ltd Transnasale zusammensetzung mit sofortiger wirkung und hoher resorbierbarkeit
BRPI0514263B8 (pt) 2004-08-20 2021-05-25 Mannkind Corp método para a síntese de bis-3,6-[4-aminobutil]-2,5-dicetopiperazina n-protegida
CN104436170B (zh) 2004-08-23 2018-02-23 曼金德公司 用于药物输送的二酮哌嗪盐
US7115561B2 (en) * 2004-09-22 2006-10-03 Patterson James A Medicament composition and method of administration
US8202550B2 (en) 2004-10-11 2012-06-19 Nasaleze Ppm Limited Compositions for intranasal administration
GB2420707A (en) * 2004-10-11 2006-06-07 Nasaleze Patents Ltd Compositions for intranasal administration
WO2006040596A2 (en) * 2004-10-11 2006-04-20 Nasaleze Ppm Limited Compositions for intranasal administration
JP2009504767A (ja) * 2005-08-17 2009-02-05 フレミング・アンド・カンパニー・ファーマシューティカルズ ビタミンｂ１２鼻用スプレーおよび使用方法
EP1928484B1 (de) 2005-08-26 2010-02-24 The Board Of Trustees Of The Leland Stanford Junior University Verfahren zur behandlung von kopfschmerzen durch verabreichung von oxytocin
AU2006290870B2 (en) 2005-09-14 2013-02-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
JP5599975B2 (ja) 2006-02-22 2014-10-01 マンカインド コーポレイション ジケトピペラジン及び活性薬剤を含有する微粒子の製剤特性の改善方法
CN101668544B (zh) 2006-12-26 2013-04-24 株式会社新日本科学 经鼻投用制剂
EP2211842B1 (de) * 2007-10-24 2015-08-12 MannKind Corporation Eine inhalierbare, trockenpulver-formulierung, enthaltend glp-1 zur verwendung in der behandlung von hyperglykämie und diabetes durch pulmonale verabreichung
US8499757B2 (en) 2008-06-13 2013-08-06 Mannkind Corporation Dry powder inhaler and system for drug delivery
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2904623T3 (es) 2008-06-20 2022-04-05 Mannkind Corp Aparato interactivo para establecer un perfil en tiempo real de esfuerzos de inhalación
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US8538707B2 (en) 2009-03-11 2013-09-17 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
EP2429495A4 (de) 2009-05-15 2014-01-22 Shin Nippon Biomedical Lab Ltd Intranasale pharmazeutische zusammensetzung mit verbesserter pharmakokinetik
RU2509555C2 (ru) 2009-06-12 2014-03-20 Маннкайнд Корпорейшн Микрочастицы дикетопиперазина с определенными удельными площадями поверхности
US8827946B2 (en) 2009-07-31 2014-09-09 Shin Nippon Biomedical Laboratories, Ltd. Intranasal granisetron and nasal applicator
US9561185B2 (en) 2009-09-02 2017-02-07 Nippon Soda Co., Ltd. Hydroxypropyl cellulose particles
ES2623328T3 (es) * 2009-09-18 2017-07-11 Sitec Pharmabio Sl Procedimiento para la deshidratación de productos en polvo
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
JP5670430B2 (ja) 2010-03-19 2015-02-18 第一三共株式会社 経鼻投与用組成物及びその製造方法
MX359281B (es) 2010-06-21 2018-09-21 Mannkind Corp Sistema y metodos para suministrar un farmaco en polvo seco.
US8925726B2 (en) 2011-04-01 2015-01-06 Mannkind Corporation Blister package for pharmaceutical cartridges
SE536091C2 (sv) 2011-04-14 2013-04-30 Pep Tonic Medical Ab Farmaceutisk komposition innehållande oxytocin eller fragment eller varianter därav och åtminstone en icke-jonisk cellulosaeter
US20130040923A1 (en) 2011-05-13 2013-02-14 Trimel Pharmaceuticals Corporation Intranasal lower dosage strength testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder
US20130045958A1 (en) 2011-05-13 2013-02-21 Trimel Pharmaceuticals Corporation Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder
US9757388B2 (en) 2011-05-13 2017-09-12 Acerus Pharmaceuticals Srl Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
JP5717658B2 (ja) * 2012-01-13 2015-05-13 シスメックス株式会社 副腎皮質刺激ホルモンの検出方法および吸着剤
US9789071B2 (en) 2012-06-27 2017-10-17 G2B Pharma, Inc. Intranasal formulation of epinephrine for the treatment of anaphylaxis
MX354163B (es) 2012-07-12 2018-02-15 Mannkind Corp Sistemas y métodos de suministro de fármaco en polvo seco.
EP2911690A1 (de) 2012-10-26 2015-09-02 MannKind Corporation Inhalierbare influenza-impfstoffzusammensetzungen und verfahren
SMT202000349T1 (it) 2013-03-04 2020-09-10 Besins Healthcare Lu Sarl Composizione farmaceutica secche comprendenti nanoparticelle di agente attivo legate a particelle di vettore
US11744838B2 (en) 2013-03-15 2023-09-05 Acerus Biopharma Inc. Methods of treating hypogonadism with transnasal testosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event
SG10201708090TA (en) 2013-03-15 2017-11-29 Mannkind Corp Microcrystalline diketopiperazine compositions and methods
KR102321339B1 (ko) 2013-07-18 2021-11-02 맨카인드 코포레이션 열-안정성 건조 분말 약제학적 조성물 및 방법
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
JP2016531140A (ja) * 2013-09-03 2016-10-06 ジー２ビー ファーマ インコーポレーテッド 心肺機能蘇生（ｃｐｒ）、心臓の生命維持（ｃｌｓ）、アナフィラキシー及び／又はアナフィラクトイド反応の治療のための経鼻投与製剤
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
RU2017127734A (ru) 2015-01-07 2019-02-07 Трайджемина, Инк. Магнийсодержащие составы окситоцина и способы применения
EP3442560B1 (de) 2016-04-12 2024-11-20 Tonix Pharma Limited Magnesiumhaltige oxytocinformulierungen und verfahren zur verwendung
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
JP7321096B2 (ja) 2017-11-27 2023-08-04 あすか製薬株式会社 粉末経鼻投与製剤
CN108158978A (zh) * 2018-03-26 2018-06-15 厦门传福堂药业有限公司 一种高分子水性凝胶及其制备方法和用途
KR20220009407A (ko) * 2019-05-16 2022-01-24 신 니뽄 바이오메디칼 라보라토리즈, 엘티디. 경비 투여용의 분말 제제 및 그 제조 방법
WO2022132018A1 (en) * 2020-12-16 2022-06-23 Liw Innovation Ab A new powder composition

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6034925B2 (ja) † 1979-07-31 1985-08-12 帝人株式会社 持続性鼻腔用製剤およびその製造法
JPS607965B2 (ja) * 1980-08-07 1985-02-28 帝人株式会社 鼻腔粘膜投与用粉剤の製造法
JPS59163313A (ja) * 1983-03-09 1984-09-14 Teijin Ltd 経鼻投与用ペプチドホルモン類組成物
EP0187433B1 (de) * 1983-08-01 1990-12-27 Teijin Limited Pulverige pharmazeutische Zusammensetzung zur Anwendung auf die Schleimhaut der Mund- oder Nasenhöhle
JPS6032714A (ja) * 1983-08-01 1985-02-19 Teijin Ltd 鼻腔粘膜に適用するための安定化された粉末状薬学的組成物
JPS6034925A (ja) 1983-08-04 1985-02-22 Mitsubishi Chem Ind Ltd ２−ヒドロキシイソフタルアルデヒド類の製造法
JPS60224616A (ja) * 1984-04-24 1985-11-09 Teijin Ltd 経鼻投与用組成物
JPS6242888A (ja) 1985-08-21 1987-02-24 カシオ計算機株式会社 太陽電池を備えたｉｃカ−ド
GB2193891B (en) 1986-08-18 1990-07-25 Sandoz Ltd Nasal pharmaceutical composition containing a somatostatin anologue.
JP3068924B2 (ja) 1990-11-29 2000-07-24 旭硝子株式会社 熱線遮断膜
EP0571671B1 (de) * 1992-05-26 1997-09-17 The Procter & Gamble Company Pulverförmige pharmazeutische Zusammensetzung
US5626871A (en) * 1992-06-12 1997-05-06 Teijin Limited Preparation for intratracheobronchial administration
ATE215377T1 (de) 1993-07-30 2002-04-15 Teijin Ltd Pulver zur nasalen verabreichung peptidischer oder proteinischer arzneistoffe
JPH07242550A (ja) 1994-03-02 1995-09-19 Teijin Ltd 二次性副甲状腺機能亢進症治療剤
US6881423B2 (en) * 1996-02-27 2005-04-19 Teijin Limited Powdery composition for nasal administration

Also Published As

Publication number Publication date
CN1216464A (zh) 1999-05-12
DK0943326T4 (da) 2007-01-22
EP0943326B2 (de) 2006-12-20
DE69724272T2 (de) 2004-06-09
US20100047206A1 (en) 2010-02-25
US20020012688A1 (en) 2002-01-31
JP3634380B2 (ja) 2005-03-30
CA2247191C (en) 2005-01-04
CA2247191A1 (en) 1997-09-04
EP0943326B1 (de) 2003-08-20
AU722319B2 (en) 2000-07-27
ES2205177T5 (es) 2007-08-01
EP0943326A4 (de) 2000-12-20
EP0943326A1 (de) 1999-09-22
US6881423B2 (en) 2005-04-19
KR100568436B1 (ko) 2007-04-25
US8206748B2 (en) 2012-06-26
ES2205177T3 (es) 2004-05-01
AU2230297A (en) 1997-09-16
DE69724272T3 (de) 2007-05-10
CN1155368C (zh) 2004-06-30
KR19990087261A (ko) 1999-12-15
DK0943326T3 (da) 2003-12-08
US7731990B2 (en) 2010-06-08
WO1997031626A1 (en) 1997-09-04
PT943326E (pt) 2003-12-31
US20040219108A1 (en) 2004-11-04
DE69724272D1 (de) 2003-09-25

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