ATE247471T1 - Cisplatin und topotecan enthaltende zusammensetzung als antitumor. - Google Patents

Cisplatin und topotecan enthaltende zusammensetzung als antitumor.

Info

Publication number
ATE247471T1
ATE247471T1 AT92925253T AT92925253T ATE247471T1 AT E247471 T1 ATE247471 T1 AT E247471T1 AT 92925253 T AT92925253 T AT 92925253T AT 92925253 T AT92925253 T AT 92925253T AT E247471 T1 ATE247471 T1 AT E247471T1
Authority
AT
Austria
Prior art keywords
human
compound
topotecan
antitumor
composition containing
Prior art date
Application number
AT92925253T
Other languages
English (en)
Inventor
Randall Keith Johnson
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of ATE247471T1 publication Critical patent/ATE247471T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Seasonings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT92925253T 1991-11-15 1992-11-13 Cisplatin und topotecan enthaltende zusammensetzung als antitumor. ATE247471T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79304191A 1991-11-15 1991-11-15
PCT/US1992/009864 WO1993009782A1 (en) 1991-11-15 1992-11-13 Combination chemotherapy

Publications (1)

Publication Number Publication Date
ATE247471T1 true ATE247471T1 (de) 2003-09-15

Family

ID=25158913

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92925253T ATE247471T1 (de) 1991-11-15 1992-11-13 Cisplatin und topotecan enthaltende zusammensetzung als antitumor.

Country Status (14)

Country Link
US (1) US5633016A (de)
EP (3) EP1393730A3 (de)
JP (1) JPH07501079A (de)
AT (1) ATE247471T1 (de)
AU (1) AU671605B2 (de)
CA (1) CA2123321C (de)
DE (1) DE69233169T2 (de)
DK (1) DK0612248T3 (de)
ES (1) ES2204894T3 (de)
MX (1) MX9206577A (de)
NZ (1) NZ245112A (de)
PT (1) PT101061B (de)
WO (1) WO1993009782A1 (de)
ZA (1) ZA928771B (de)

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US6274576B1 (en) 1995-06-27 2001-08-14 The Henry Jackson Foundation For The Advancement Of Military Medicine Method of dynamic retardation of cell cycle kinetics to potentiate cell damage
CA2225682A1 (en) * 1995-06-27 1997-01-16 Henry M. Jackson Foundation For The Advancement Of Military Medicine Method of dynamic retardation of cell cycle kinetics to potentiate cell damage
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US6858598B1 (en) 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
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US7105492B2 (en) * 1999-03-09 2006-09-12 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Camptothecin derivatives having antitumor activity
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US10293056B1 (en) 2000-05-24 2019-05-21 Board Of Regents, The University Of Texas System Methods and compositions for non-viral gene therapy for treatment of hyperproliferative diseases
DE10032256C2 (de) * 2000-07-03 2003-06-05 Infineon Technologies Ag Chip-ID-Register-Anordnung
CA2429769C (en) * 2000-12-07 2016-04-26 Board Of Regents, The University Of Texas System Methods of treatment involving human mda-7
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EP1490101A4 (de) * 2002-03-05 2006-09-20 Univ Texas Verfahren zur verbesserung der immuninduktion mit mda-7
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BRPI0408063A (pt) * 2003-03-03 2006-02-14 Univ Texas métodos e composições envolvendo mda-7
US8034790B2 (en) * 2003-12-01 2011-10-11 Introgen Therapeutics Use of MDA-7 to inhibit pathogenic infectious organisms
US20070281041A1 (en) * 2004-03-02 2007-12-06 Introgen Therapeutics, Inc. Compositions and Methods Involving MDA-7 for the Treatment of Cancer
CA2597329C (en) * 2005-02-08 2016-10-11 Board Of Regents, The University Of Texas System Compositions and methods involving mda-7 for the treatment of cancer
US8668905B2 (en) * 2005-05-12 2014-03-11 University Of South Florida P53 vaccines for the treatment of cancers
US20100190180A1 (en) * 2005-07-06 2010-07-29 Heidi Kay Materials and Methods for Screening, Diagnosis and Prognosis of Conditions Associated With Stat Protein Expression
CN101351213B (zh) * 2005-09-07 2013-10-02 詹纳里克斯公司 使用表达gm-csf的痘病毒系统性治疗转移性癌和/或全身散布性癌
US8980246B2 (en) 2005-09-07 2015-03-17 Sillajen Biotherapeutics, Inc. Oncolytic vaccinia virus cancer therapy
WO2007092944A2 (en) * 2006-02-08 2007-08-16 Introgen Therapeutics, Inc. Compositions and methods involving gene therapy and proteasome modulation
US20110028536A1 (en) * 2006-08-18 2011-02-03 Gjerset Ruth A Methods and compositions for topoisomerase i modulated tumor suppression
US8178564B2 (en) * 2006-11-06 2012-05-15 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8173686B2 (en) 2006-11-06 2012-05-08 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168661B2 (en) * 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
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US20110033528A1 (en) * 2009-08-05 2011-02-10 Poniard Pharmaceuticals, Inc. Stabilized picoplatin oral dosage form
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DK2981624T3 (da) 2013-04-05 2020-03-02 Myriad Genetics Inc Fremgangsmåder til vurdering af homolog rekombinationsdeficiens og forudsigelse af respons på cancerbehandling
EP3073825A4 (de) * 2013-11-25 2017-06-21 The University of Toledo Inhibitoren von ercc1-xpf und verfahren zur verwendung davon
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ES2946251T3 (es) 2014-08-15 2023-07-14 Myriad Genetics Inc Métodos y materiales para evaluar la deficiencia de recombinación homóloga
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Also Published As

Publication number Publication date
EP1393729A2 (de) 2004-03-03
WO1993009782A1 (en) 1993-05-27
DE69233169D1 (de) 2003-09-25
EP1393730A3 (de) 2004-03-17
AU671605B2 (en) 1996-09-05
NZ245112A (en) 1995-07-26
JPH07501079A (ja) 1995-02-02
EP0612248B1 (de) 2003-08-20
ES2204894T3 (es) 2004-05-01
MX9206577A (es) 1993-05-01
US5633016A (en) 1997-05-27
CA2123321A1 (en) 1993-05-27
EP1393729A3 (de) 2004-03-17
CA2123321C (en) 2003-09-30
DE69233169T2 (de) 2004-05-27
PT101061B (pt) 1999-07-30
AU3137993A (en) 1993-06-15
DK0612248T3 (da) 2003-12-08
EP1393730A2 (de) 2004-03-03
EP0612248A1 (de) 1994-08-31
HK1012268A1 (en) 1999-07-30
PT101061A (pt) 1994-06-30
EP0612248A4 (en) 1996-05-08
ZA928771B (en) 1993-09-08

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