ATE24838T1 - Lyophilisierte zusammensetzungen, ihre herstellung und verwendung. - Google Patents

Lyophilisierte zusammensetzungen, ihre herstellung und verwendung.

Info

Publication number
ATE24838T1
ATE24838T1 AT83306215T AT83306215T ATE24838T1 AT E24838 T1 ATE24838 T1 AT E24838T1 AT 83306215 T AT83306215 T AT 83306215T AT 83306215 T AT83306215 T AT 83306215T AT E24838 T1 ATE24838 T1 AT E24838T1
Authority
AT
Austria
Prior art keywords
preparation
slurry
lyophilized compositions
syringe
aminocaproic acid
Prior art date
Application number
AT83306215T
Other languages
English (en)
Inventor
Grace Wood
Benjamin R Duce
Russell W Pelham
James Woiszwillo
Original Assignee
Serono Pharma Partners
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Serono Pharma Partners filed Critical Serono Pharma Partners
Application granted granted Critical
Publication of ATE24838T1 publication Critical patent/ATE24838T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT83306215T 1982-11-16 1983-10-13 Lyophilisierte zusammensetzungen, ihre herstellung und verwendung. ATE24838T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/442,151 US4540410A (en) 1982-11-16 1982-11-16 Lyophilized compositions, preparation and use thereof
EP83306215A EP0109188B1 (de) 1982-11-16 1983-10-13 Lyophilisierte Zusammensetzungen, ihre Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
ATE24838T1 true ATE24838T1 (de) 1987-01-15

Family

ID=23755732

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83306215T ATE24838T1 (de) 1982-11-16 1983-10-13 Lyophilisierte zusammensetzungen, ihre herstellung und verwendung.

Country Status (12)

Country Link
US (1) US4540410A (de)
EP (1) EP0109188B1 (de)
AT (1) ATE24838T1 (de)
AU (1) AU558164B2 (de)
CA (1) CA1228542A (de)
DE (1) DE3369070D1 (de)
DK (1) DK164538C (de)
ES (2) ES527289A0 (de)
IL (1) IL69923A (de)
NO (1) NO165625C (de)
PT (1) PT77621B (de)
ZA (1) ZA837407B (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6144825A (ja) * 1984-08-09 1986-03-04 Unitika Ltd 止血剤
JPS6150912A (ja) * 1984-08-16 1986-03-13 Shionogi & Co Ltd リポソ−ム製剤の製造法
US4743229A (en) * 1986-09-29 1988-05-10 Collagen Corporation Collagen/mineral mixing device and method
DE3816961A1 (de) * 1987-07-21 1989-02-02 Wasserburger Arzneimittelwerk Injektionsspritze fuer medizinische zwecke
EP0365704A1 (de) * 1988-10-26 1990-05-02 Zentralna Problemna Laboratoria Po Kryobiologia I Lyophilisazia Biopräparat für Hämostase bei Magenblutungen
US5063178A (en) * 1990-03-19 1991-11-05 Medex, Inc. Freeze-dried blood gas sensor
FR2694496A1 (fr) * 1992-08-05 1994-02-11 Bernstein Serge Procédé pour l'obtention d'un produit permettant l'expansion des seins et le traitement des rides.
US7871637B2 (en) * 1996-08-27 2011-01-18 Baxter International Inc. Dry hemostatic compositions and methods for their preparation
US8303981B2 (en) 1996-08-27 2012-11-06 Baxter International Inc. Fragmented polymeric compositions and methods for their use
US6066325A (en) * 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US8603511B2 (en) 1996-08-27 2013-12-10 Baxter International, Inc. Fragmented polymeric compositions and methods for their use
US7435425B2 (en) * 2001-07-17 2008-10-14 Baxter International, Inc. Dry hemostatic compositions and methods for their preparation
US6527738B1 (en) * 1999-04-30 2003-03-04 Prismedical Corporation Drug delivery pack
US20010037091A1 (en) * 1999-12-29 2001-11-01 Wironen John F. System for reconstituting pastes and methods of using same
US8834864B2 (en) * 2003-06-05 2014-09-16 Baxter International Inc. Methods for repairing and regenerating human dura mater
US7927626B2 (en) * 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
US7998106B2 (en) 2004-05-03 2011-08-16 Thorne Jr Gale H Safety dispensing system for hazardous substances
US7101354B2 (en) 2004-05-03 2006-09-05 Infusive Technologies, Llc Mixing syringe with and without flush
MX2008014847A (es) * 2006-05-31 2009-04-30 Baxter Int Metodo para crecimiento interno en la celula dirigido y regeneracion controlada de los tejidos en la cirugia espinal.
EP1870649A1 (de) 2006-06-20 2007-12-26 Octapharma AG Gefriertocknung zum Erzielen einer bestimmte Restfeuchte durch beschränkte Desorptionsenergiepegeln.
TWI436793B (zh) * 2006-08-02 2014-05-11 巴克斯特國際公司 快速作用之乾密封膠及其使用和製造方法
TWI461227B (zh) 2007-10-30 2014-11-21 Baxter Int 再生生物功能性膠原生物基質用來治療內臟或體壁缺陷的用途
EP2259803B2 (de) 2008-02-29 2019-03-13 Ferrosan Medical Devices A/S Vorrichtung zur förderung von hämostase und/oder wundheilung
US9039783B2 (en) 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
ES2532428T3 (es) 2009-06-16 2015-03-26 Baxter International Inc Esponja hemostática
MX2012007056A (es) 2009-12-16 2012-09-28 Baxter Healthcare Sa Esponja hemostatica.
SA111320355B1 (ar) 2010-04-07 2015-01-08 Baxter Heathcare S A إسفنجة لايقاف النزف
EP2575775B1 (de) 2010-06-01 2018-04-04 Baxter International Inc. Verfahren zur herstellung von trockenen und stabilen hämostatischen zusammensetzungen
JP6289096B2 (ja) * 2010-06-01 2018-03-07 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated 乾燥した安定な止血組成物を作製するためのプロセス
WO2011151386A1 (en) * 2010-06-01 2011-12-08 Baxter International Inc. Process for making dry and stable hemostatic compositions
EP4137165A1 (de) 2011-10-11 2023-02-22 Baxter International Inc. Hämostatische zusammensetzungen
AU2012318258B2 (en) 2011-10-11 2015-07-09 Baxter Healthcare S.A. Hemostatic compositions
WO2013060770A1 (en) 2011-10-27 2013-05-02 Baxter International Inc. Hemostatic compositions
RU2657955C2 (ru) 2012-03-06 2018-06-18 Ферросан Медикал Дивайсиз А/С Контейнер под давлением, содержащий гемостатическую пасту
RU2636240C2 (ru) 2012-06-12 2017-11-21 Ферросан Медикал Дивайсиз А/С Сухая гемостатическая композиция
CN105358071B (zh) 2013-06-21 2018-07-31 弗罗桑医疗设备公司 真空膨胀的干组合物和用于保留该干组合物的注射器
WO2015086028A1 (en) 2013-12-11 2015-06-18 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
US11046818B2 (en) 2014-10-13 2021-06-29 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
CN107206165B (zh) 2014-12-24 2020-10-23 弗罗桑医疗设备公司 用于保持并混合第一和第二物质的注射器
CA2986981A1 (en) 2015-07-03 2017-01-12 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
EP3790600B1 (de) 2018-05-09 2023-12-27 Ferrosan Medical Devices A/S Verfahren zur herstellung einer hämostatischen zusammensetzung

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB450145A (en) * 1934-01-13 1936-07-06 Sharp & Dohme Inc Lyophilic biologically active substances and process of producing the same
GB455027A (en) * 1935-01-04 1935-08-01 Sharp & Dohme Inc Normal serum product and process of producing the same
US2380339A (en) * 1941-07-10 1945-07-10 Fromm Lab Inc Method and apparatus for preserving biological substances
US3743714A (en) * 1970-12-04 1973-07-03 Cis Radiopharmaceuticals Inc Novel carrier preparations for injectable radioactive compositions
US4006220A (en) * 1975-06-04 1977-02-01 Gottlieb Sheldon K Compositions and methods useful for repairing depressed cutaneous scars
US4191751A (en) * 1975-06-04 1980-03-04 Gottlieb Sheldon K Method for promoting growth of new connective tissue over surface wounds
US4167945A (en) * 1977-01-31 1979-09-18 Gottlieb Sheldon K Method for enhancing the healing of grafted tissue

Also Published As

Publication number Publication date
DE3369070D1 (en) 1987-02-19
PT77621A (en) 1983-12-01
US4540410A (en) 1985-09-10
IL69923A (en) 1987-03-31
ES8600733A1 (es) 1985-11-01
DK164538C (da) 1993-01-11
NO834183L (no) 1984-05-18
ES546583A0 (es) 1987-07-01
ES8706312A1 (es) 1987-07-01
AU558164B2 (en) 1987-01-22
EP0109188A1 (de) 1984-05-23
CA1228542A (en) 1987-10-27
ES527289A0 (es) 1985-11-01
ZA837407B (en) 1985-05-29
DK521283D0 (da) 1983-11-15
NO165625C (no) 1991-03-13
PT77621B (en) 1986-03-19
DK164538B (da) 1992-07-13
AU2091683A (en) 1984-05-24
EP0109188B1 (de) 1987-01-14
DK521283A (da) 1984-05-17
NO165625B (no) 1990-12-03

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee