ATE249478T1 - Harnstoff- und thioharnstoffderivate von antibiotisch wirksamen glykopeptiden - Google Patents

Harnstoff- und thioharnstoffderivate von antibiotisch wirksamen glykopeptiden

Info

Publication number: ATE249478T1
Authority: AT; Austria
Prior art keywords: urea; thiourea derivatives; antibiotic glycopeptides; derivatives; glycopeptides
Prior art date: 1997-05-20

Application number

AT98303494T

Other languages

English (en)

Inventor

Richard Craig Thompson

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-05-20

Filing date

1998-05-05

Publication date

2003-09-15

1998-05-05 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2003-09-15 Application granted granted Critical

2003-09-15 Publication of ATE249478T1 publication Critical patent/ATE249478T1/de

Links

XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 2
102000002068 Glycopeptides Human genes 0.000 title 1
108010015899 Glycopeptides Proteins 0.000 title 1
230000003115 biocidal effect Effects 0.000 title 1
239000004202 carbamide Substances 0.000 title 1
UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical class NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 title 1
230000000844 anti-bacterial effect Effects 0.000 abstract 2
229940088710 antibiotic agent Drugs 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000007858 starting material Substances 0.000 abstract 1
-1 thiocarbamoyl Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
General Chemical & Material Sciences (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

AT98303494T 1997-05-20 1998-05-05 Harnstoff- und thioharnstoffderivate von antibiotisch wirksamen glykopeptiden ATE249478T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US4719697P	1997-05-20	1997-05-20

Publications (1)

Publication Number	Publication Date
ATE249478T1 true ATE249478T1 (de)	2003-09-15

Family

ID=21947590

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98303494T ATE249478T1 (de)	1997-05-20	1998-05-05	Harnstoff- und thioharnstoffderivate von antibiotisch wirksamen glykopeptiden

Country Status (10)

Country	Link
US (1)	US5919771A (de)
EP (1)	EP0881230B1 (de)
JP (1)	JP4086326B2 (de)
AT (1)	ATE249478T1 (de)
AU (1)	AU7285498A (de)
CA (1)	CA2290388A1 (de)
DE (1)	DE69817915T2 (de)
ES (1)	ES2206839T3 (de)
PT (1)	PT881230E (de)
WO (1)	WO1998052592A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT1140993E (pt)	1998-12-23	2003-10-31	Theravance Inc	Derivados de glicopeptidos e composicoes farmaceuticas contendo os mesmos
US8778874B2 (en)	2004-11-29	2014-07-15	National University Corporation Nagoya University	Glycopeptide antibiotic monomer derivatives
CA2623198C (en)	2005-09-22	2014-08-05	Medivas, Llc	Bis-(a-amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use
JP5178520B2 (ja)	2005-09-22	2013-04-10	メディバスエルエルシー	固体ポリマー送達組成物およびその使用法
CN101959900A (zh)	2007-12-26	2011-01-26	盐野义制药株式会社	糖肽类抗生素糖基化衍生物
EP2260060A4 (de)	2008-04-01	2013-01-16	Univ Cornell	Organisch lösliche chitosansalze und daraus hergestellte chitosan-abgeleitete biomaterialien

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4698327A (en) *	1985-04-25	1987-10-06	Eli Lilly And Company	Novel glycopeptide derivatives
US4643987A (en) *	1985-08-14	1987-02-17	Eli Lilly And Company	Modified glycopeptides
US5534420A (en) *	1988-07-28	1996-07-09	Eli Lilly And Company	Biotransformation of glycopeptide antibiotics
EP0409045B1 (de) *	1989-07-18	1997-11-19	Biosearch Italia S.p.A.	Aus Dalbaheptide hergestellte Pentapeptid-Antibiotika
ZA909847B (en) *	1989-12-13	1992-08-26	Lilly Co Eli	Glycopeptide derivatives
TW213468B (de) *	1991-06-29	1993-09-21	Hoechst Ag
US5840684A (en) *	1994-01-28	1998-11-24	Eli Lilly And Company	Glycopeptide antibiotic derivatives
TW457248B (en) *	1994-01-28	2001-10-01	Lilly Co Eli	Glycopeptide antibiotic derivatives
AU2441697A (en) *	1996-04-12	1997-11-07	Eli Lilly And Company	Covalently-linked glycopeptide dimers
US5919756A (en) *	1996-06-28	1999-07-06	Eli Lilly And Company	Amides

1998
- 1998-04-30 US US09/070,219 patent/US5919771A/en not_active Expired - Fee Related
- 1998-05-05 ES ES98303494T patent/ES2206839T3/es not_active Expired - Lifetime
- 1998-05-05 PT PT98303494T patent/PT881230E/pt unknown
- 1998-05-05 WO PCT/US1998/009131 patent/WO1998052592A1/en not_active Ceased
- 1998-05-05 DE DE69817915T patent/DE69817915T2/de not_active Expired - Fee Related
- 1998-05-05 AU AU72854/98A patent/AU7285498A/en not_active Abandoned
- 1998-05-05 AT AT98303494T patent/ATE249478T1/de not_active IP Right Cessation
- 1998-05-05 CA CA002290388A patent/CA2290388A1/en not_active Abandoned
- 1998-05-05 EP EP98303494A patent/EP0881230B1/de not_active Expired - Lifetime
- 1998-05-05 JP JP55040398A patent/JP4086326B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0881230A2 (de)	1998-12-02
DE69817915T2 (de)	2004-07-15
CA2290388A1 (en)	1998-11-26
EP0881230B1 (de)	2003-09-10
EP0881230A3 (de)	1998-12-23
PT881230E (pt)	2004-02-27
DE69817915D1 (de)	2003-10-16
JP4086326B2 (ja)	2008-05-14
WO1998052592A1 (en)	1998-11-26
US5919771A (en)	1999-07-06
AU7285498A (en)	1998-12-11
JP2001526682A (ja)	2001-12-18
ES2206839T3 (es)	2004-05-16

Legal Events

Date

Code

Title

Description

2004-05-15

UEP

Publication of translation of european patent specification

Ref document number: 0881230

Country of ref document: EP

2011-02-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
NO930059L (no)	1993-01-08	O-glykosylert ifn-alfa
NO932869D0 (no)	1993-08-12	7-(substituerte)-9-((substituerte glycyl)amido)-6-demetyl-6-deoksytetracykliner
IL135536A0 (en)	2001-05-20	Ortho-anthranilamide derivatives and pharmaceutical compositions containing the same
FI933567A0 (fi)	1993-08-12	Nya 7-(substituerad)-8-(substituerad)-9-(substituerad amino)-6-demetyl-6-deoxitetracykliner
WO1999002514A3 (en)	2001-05-10	Epothilone derivatives
ATE206391T1 (de)	2001-10-15	7-(subtituierte)-8-(substituierte)-9- (substituiertes glycyl)amido-6-demethyl-6- deoxytetracycline
PT881229E (pt)	2003-11-28	Antibioticos hexapeptidicos alquilados
LV12443A (en)	2000-03-20	7-(2-Aminoethyl)-benzothiazolones
AU1634288A (en)	1988-11-24	Cyclic anticoagulant peptides
AU1634388A (en)	1988-11-24	Cyclic anticoagulant peptides
DE69817915D1 (de)	2003-10-16	Harnstoff- und Thioharnstoffderivate von antibiotisch wirksamen Glykopeptiden
NO942983D0 (no)	1994-08-12	Farmasöytiske sammensetninger
FI892222A0 (fi)	1989-05-09	Peptidalkoholer med antikoagulantverkan.
DE69826137D1 (de)	2004-10-14	Potentieller effektor der grb7-familie von signalproteinen
ES2108016T3 (es)	1997-12-16	Triazolopiridazinas substituidas.
DK1073447T3 (da)	2007-09-03	N1-modificerede glycopeptider
ES2169053T3 (es)	2002-07-01	Compuestos intermedios en la sintesis de cefalosporinas.
DK0879825T3 (da)	2004-02-02	Derivater af antibiotikum A82846A (Chlororienticin A)
FI946031L (fi)	1994-12-22	Kringleä sisältävien proteiinien puhdistus ja etenkin t-PA:n
ITMI950971A1 (it)	1996-03-21	Derivati aminotiazolici di cefalosporine aventi attivita' antibatterica