ATE249886T1 - Verfahren und vorrichtung zum kontrollierten bewegen und plazieren von flüssigkeitstropfen - Google Patents

Verfahren und vorrichtung zum kontrollierten bewegen und plazieren von flüssigkeitstropfen

Info

Publication number
ATE249886T1
ATE249886T1 AT00966067T AT00966067T ATE249886T1 AT E249886 T1 ATE249886 T1 AT E249886T1 AT 00966067 T AT00966067 T AT 00966067T AT 00966067 T AT00966067 T AT 00966067T AT E249886 T1 ATE249886 T1 AT E249886T1
Authority
AT
Austria
Prior art keywords
placing
liquid drops
sup
controlled moving
moving
Prior art date
Application number
AT00966067T
Other languages
English (en)
Inventor
Karsten Reihs
Burkhard Koehler
Dieter Ruehle
Original Assignee
Sunyx Surface Nanotechnologies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sunyx Surface Nanotechnologies filed Critical Sunyx Surface Nanotechnologies
Application granted granted Critical
Publication of ATE249886T1 publication Critical patent/ATE249886T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/089—Virtual walls for guiding liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Vibration Prevention Devices (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Manipulator (AREA)
  • Micromachines (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Extraction Or Liquid Replacement (AREA)
AT00966067T 1999-10-05 2000-09-22 Verfahren und vorrichtung zum kontrollierten bewegen und plazieren von flüssigkeitstropfen ATE249886T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19947788A DE19947788A1 (de) 1999-10-05 1999-10-05 Verfahren und Vorrichtung zum Bewegen von Flüssigkeiten
PCT/EP2000/009272 WO2001024934A1 (de) 1999-10-05 2000-09-22 Verfahren und vorrichtung zum kontrollierten bewegen und plazieren von flüssigkeitstropfen

Publications (1)

Publication Number Publication Date
ATE249886T1 true ATE249886T1 (de) 2003-10-15

Family

ID=7924464

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00966067T ATE249886T1 (de) 1999-10-05 2000-09-22 Verfahren und vorrichtung zum kontrollierten bewegen und plazieren von flüssigkeitstropfen

Country Status (8)

Country Link
US (1) US7214302B1 (de)
EP (1) EP1222031B1 (de)
JP (1) JP2003511247A (de)
AT (1) ATE249886T1 (de)
AU (1) AU779566B2 (de)
CA (1) CA2387581C (de)
DE (2) DE19947788A1 (de)
WO (1) WO2001024934A1 (de)

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DE10162064A1 (de) * 2001-12-17 2003-06-26 Sunyx Surface Nanotechnologies Hydrophobe Oberfläche mit einer Vielzahl von Elektroden
DE10162816A1 (de) * 2001-12-19 2003-07-03 Sunyx Surface Nanotechnologies Optischer Schalter
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US7141210B2 (en) 2002-04-01 2006-11-28 Palo Alto Research Center Incorporated Apparatus and method for a nanocalorimeter for detecting chemical reactions
US7833800B2 (en) 2002-04-01 2010-11-16 Palo Alto Research Center Incorporated Thermal sensing with bridge circuitry
US7473030B2 (en) 2002-04-01 2009-01-06 Palo Alto Research Center Incorporated Thermal sensing
US20090215192A1 (en) * 2004-05-27 2009-08-27 Stratos Biosystems, Llc Solid-phase affinity-based method for preparing and manipulating an analyte-containing solution
US20100075422A1 (en) * 2006-12-13 2010-03-25 Qiagen Gmbh Transfection microarrays
DE102007018056A1 (de) * 2007-04-17 2008-10-23 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren und Vorrichtung zur Tropfenmanipulation
US8367370B2 (en) * 2008-02-11 2013-02-05 Wheeler Aaron R Droplet-based cell culture and cell assays using digital microfluidics
US8187864B2 (en) 2008-10-01 2012-05-29 The Governing Council Of The University Of Toronto Exchangeable sheets pre-loaded with reagent depots for digital microfluidics
US8053239B2 (en) 2008-10-08 2011-11-08 The Governing Council Of The University Of Toronto Digital microfluidic method for protein extraction by precipitation from heterogeneous mixtures
EP2346777A4 (de) 2008-10-10 2014-10-01 Univ Toronto Hybride digitale mikrofluidische kanalvorrichtungen und herstellungsverfahren dafür
US8202736B2 (en) * 2009-02-26 2012-06-19 The Governing Council Of The University Of Toronto Method of hormone extraction using digital microfluidics
US9851365B2 (en) 2009-02-26 2017-12-26 The Governing Council Of The University Of Toronto Digital microfluidic liquid-liquid extraction device and method of use thereof
US10232374B2 (en) 2010-05-05 2019-03-19 Miroculus Inc. Method of processing dried samples using digital microfluidic device
WO2012040861A1 (en) 2010-10-01 2012-04-05 The Governing Council Of The University Of Toronto Digital microfluidic devices and methods incorporating a solid phase
WO2016197103A1 (en) 2015-06-05 2016-12-08 Miroculus Inc. Air-matrix digital microfluidics apparatuses and methods for limiting evaporation and surface fouling
WO2016197106A1 (en) 2015-06-05 2016-12-08 Miroculus Inc. Evaporation management in digital microfluidic devices
CN109715781A (zh) 2016-08-22 2019-05-03 米罗库鲁斯公司 用于数字微流控设备中的并行液滴控制的反馈系统
EP3563151A4 (de) 2016-12-28 2020-08-19 Miroculus Inc. Digitale mikrofluidische vorrichtung und verfahren
US11623219B2 (en) 2017-04-04 2023-04-11 Miroculus Inc. Digital microfluidics apparatuses and methods for manipulating and processing encapsulated droplets
US11413617B2 (en) 2017-07-24 2022-08-16 Miroculus Inc. Digital microfluidics systems and methods with integrated plasma collection device
JP7341124B2 (ja) 2017-09-01 2023-09-08 ミロキュラス インコーポレイテッド デジタルマイクロ流体デバイスおよびその使用方法
CN107649223B (zh) * 2017-09-27 2019-10-15 京东方科技集团股份有限公司 液滴控制检测器件及其工作方法
CA3096855A1 (en) 2018-05-23 2019-11-28 Miroculus Inc. Control of evaporation in digital microfluidics
WO2020160520A1 (en) 2019-01-31 2020-08-06 Miroculus Inc. Non fouling compositions and methods for manipulating and processing encapsulated droplets
WO2020210292A1 (en) 2019-04-08 2020-10-15 Miroculus Inc. Multi-cartridge digital microfluidics apparatuses and methods of use
WO2021016614A1 (en) 2019-07-25 2021-01-28 Miroculus Inc. Digital microfluidics devices and methods of use thereof
US11772093B2 (en) * 2022-01-12 2023-10-03 Miroculus Inc. Methods of mechanical microfluidic manipulation

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Also Published As

Publication number Publication date
DE50003758D1 (de) 2003-10-23
WO2001024934A1 (de) 2001-04-12
US7214302B1 (en) 2007-05-08
CA2387581C (en) 2009-06-16
DE19947788A1 (de) 2001-04-12
EP1222031B1 (de) 2003-09-17
CA2387581A1 (en) 2001-04-12
AU779566B2 (en) 2005-01-27
EP1222031A1 (de) 2002-07-17
AU7658900A (en) 2001-05-10
JP2003511247A (ja) 2003-03-25

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