ATE250664T1 - In vitro reifen von oozyten mit inhibitin/activin kombinationen - Google Patents

In vitro reifen von oozyten mit inhibitin/activin kombinationen

Info

Publication number
ATE250664T1
ATE250664T1 AT94909788T AT94909788T ATE250664T1 AT E250664 T1 ATE250664 T1 AT E250664T1 AT 94909788 T AT94909788 T AT 94909788T AT 94909788 T AT94909788 T AT 94909788T AT E250664 T1 ATE250664 T1 AT E250664T1
Authority
AT
Austria
Prior art keywords
oocytes
activin
inhibitin
combinations
vitro
Prior art date
Application number
AT94909788T
Other languages
English (en)
Inventor
Baha M Alak
Richard L Stouffer
Don P Wolf
Teresa K Woodruff
Original Assignee
Genentech Inc
Medical Res Foundation Of Oreg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc, Medical Res Foundation Of Oreg filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE250664T1 publication Critical patent/ATE250664T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/54Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0608Germ cells
    • C12N5/0609Oocytes, oogonia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/02Atmosphere, e.g. low oxygen conditions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/60Buffer, e.g. pH regulation, osmotic pressure
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/16Activin; Inhibin; Mullerian inhibiting substance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Reproductive Health (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Ink Jet (AREA)
AT94909788T 1993-02-23 1994-02-18 In vitro reifen von oozyten mit inhibitin/activin kombinationen ATE250664T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/021,404 US5563059A (en) 1993-02-23 1993-02-23 Use of human inhibin and human activin to increase the number of mature primate oocytes
PCT/US1994/002008 WO1994019455A1 (en) 1993-02-23 1994-02-18 In vitro maturation of oocytes with inhibin, activin or inhibin/activin combinations

Publications (1)

Publication Number Publication Date
ATE250664T1 true ATE250664T1 (de) 2003-10-15

Family

ID=21804022

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94909788T ATE250664T1 (de) 1993-02-23 1994-02-18 In vitro reifen von oozyten mit inhibitin/activin kombinationen

Country Status (11)

Country Link
US (2) US5563059A (de)
EP (1) EP0686192B1 (de)
JP (1) JPH08507211A (de)
AT (1) ATE250664T1 (de)
AU (1) AU672103B2 (de)
CA (1) CA2154447C (de)
DE (1) DE69433174T2 (de)
DK (1) DK0686192T3 (de)
ES (1) ES2208655T3 (de)
PT (1) PT686192E (de)
WO (1) WO1994019455A1 (de)

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US6143564A (en) * 1998-07-07 2000-11-07 University Of Hawaii Use of the polar body chromosomes for the production of embryos and normal offspring
JP2002521025A (ja) * 1998-07-24 2002-07-16 ザ カーネギー インスチチューション オブ ワシントン 増殖因子のTGF−βファミリーのメンバーを使用する、生殖系列幹細胞の維持および増殖のための方法。
PT1917974E (pt) 1998-07-30 2011-02-22 Xy Llc Sistema de inseminação artificial não cirúrgica em equinos
US6485972B1 (en) 1998-10-15 2002-11-26 President And Fellows Of Harvard College WNT signalling in reproductive organs
EP1124840A4 (de) * 1998-10-28 2002-07-17 Baylor College Medicine Ovarspezifische gene und proteine
US6995251B1 (en) 1999-10-28 2006-02-07 Baylor Ovary-specific genes and proteins
US20060079674A1 (en) * 1998-10-28 2006-04-13 Baylor College Of Medicine Wyeth Contraceptive targets
US20020042926A1 (en) * 1998-10-28 2002-04-11 Matzuk Martin M. Ovary-specific genes and proteins
US7335737B2 (en) * 1998-10-28 2008-02-26 Baylor College Of Medicine Ovary-specific genes and proteins
CN1353617A (zh) * 1999-02-24 2002-06-12 诺沃挪第克公司 不孕症的治疗
AU2794000A (en) 1999-02-24 2000-09-14 Novo Nordisk A/S Treatment of infertility
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US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
EP1241935A2 (de) * 1999-12-17 2002-09-25 Gerald Schatten Verfahren zur erzeugung transgener tiere
US7250292B2 (en) * 2000-01-26 2007-07-31 21St Century Medicine Hypertonic reduction of chilling injury
IL152714A (en) 2000-05-09 2014-03-31 Xy Llc High-purity spermatozoa populations carrying chromosome-x and chromosome-y
RU2193777C2 (ru) * 2000-06-15 2002-11-27 Ростовский НИИ акушерства и педиатрии Способ прогнозирования исходов программы эко и пэ
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
WO2002043486A1 (en) * 2000-11-29 2002-06-06 Xy, Inc. System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US20030135876A1 (en) * 2002-01-16 2003-07-17 Larry Mobraaten Maintenance of genetic lines using cryopreserved sperm
US6849394B2 (en) * 2002-02-21 2005-02-01 Minitube Of America Compositions comprising reproductive cell media and methods for using such compositions
WO2003076600A2 (en) * 2002-03-08 2003-09-18 Mcgill University In vitro maturation of immature human oocytes
AU2012203441B2 (en) * 2002-05-17 2015-01-29 Mount Sinai School Of Medicine Of New York University Mesoderm and definitive endoderm cell populations
EP1543110A4 (de) 2002-05-17 2006-09-06 Sinai School Medicine Mesoderm- und definitive endoderm-zellpopulationen
US20060003446A1 (en) 2002-05-17 2006-01-05 Gordon Keller Mesoderm and definitive endoderm cell populations
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
JP4595067B2 (ja) 2002-08-01 2010-12-08 エックスワイ,エルエルシー 低圧精子細胞分離システム
CA2534394C (en) 2002-08-15 2013-01-08 Xy, Inc. High resolution flow cytometer
US20040105858A1 (en) * 2002-08-29 2004-06-03 Kim Joanne Young Hee Kwak Diagnosis and treatment of infertility
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
BRPI0408857B1 (pt) 2003-03-28 2018-09-11 Inguran Llc aparelho, métodos e processos para separar partículas e para prover esperma de animal separado por sexo
ES2541121T3 (es) 2003-05-15 2015-07-16 Xy, Llc Clasificación eficiente de células haploides por sistemas de citometría de flujo
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EP1765983A4 (de) 2004-05-17 2008-10-22 Gen Hospital Corp Verfahren und zusammensetzungen zur herstellung von stammzellen aus von knochenmark abgeleiteten keimbahn-stammzellen
CA2574499C (en) 2004-07-22 2016-11-29 Monsanto Technology Llc Process for enriching a population of sperm cells
RU2281777C1 (ru) * 2005-04-21 2006-08-20 Мария Львовна Семенова Способ управления качеством ооцитов и композиция для добавления в среду культивирования ооцитов
RU2281778C1 (ru) * 2005-04-21 2006-08-20 Мария Львовна Семенова Способ культивирования зиготы и/или эмбриона и композиция для добавления в среду культивирования зигот и/или эмбрионов
US7618770B2 (en) 2005-07-29 2009-11-17 Xy, Inc. Methods and apparatus for reducing protein content in sperm cell extenders
US8874380B2 (en) 2010-12-09 2014-10-28 Rutgers, The State University Of New Jersey Method of overcoming therapeutic limitations of nonuniform distribution of radiopharmaceuticals and chemotherapy drugs
US20080113432A1 (en) * 2006-11-15 2008-05-15 Mariposa Biotechnology, Inc. Methods and compositions for reanimating cryopreserved oocytes
US20080113431A1 (en) * 2006-11-15 2008-05-15 Mariposa Biotechnology, Inc. Methods and compositions for cryopreserving oocytes
US8903660B2 (en) 2010-06-24 2014-12-02 The Invention Science Fund I, Llc Rejuvenation or preservation of germ cells
CN106350479A (zh) 2011-04-14 2017-01-25 通用医疗公司 用于自体种系线粒体能量转移的组合物和方法
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Also Published As

Publication number Publication date
EP0686192A1 (de) 1995-12-13
US5563059A (en) 1996-10-08
JPH08507211A (ja) 1996-08-06
CA2154447C (en) 2005-04-19
WO1994019455A1 (en) 1994-09-01
CA2154447A1 (en) 1994-09-01
EP0686192B1 (de) 2003-09-24
DK0686192T3 (da) 2004-02-02
DE69433174T2 (de) 2004-07-01
AU6249794A (en) 1994-09-14
DE69433174D1 (de) 2003-10-30
PT686192E (pt) 2004-02-27
US5693534A (en) 1997-12-02
AU672103B2 (en) 1996-09-19
ES2208655T3 (es) 2004-06-16

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