ATE251117T1 - Neue aminobenzophenone - Google Patents

Neue aminobenzophenone

Info

Publication number: ATE251117T1
Authority: AT; Austria
Prior art keywords: alkyl; similar; different substituents; represents hydrogen; formula
Prior art date: 1999-07-16

Application number

AT00943698T

Other languages

English (en)

Inventor

Erik Rytter Ottosen

Fredrik Bjoerkling

Original Assignee

Leo Pharma As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-07-16

Filing date

2000-07-11

Publication date

2003-10-15

2000-07-11 Application filed by Leo Pharma As filed Critical Leo Pharma As

2003-10-15 Application granted granted Critical

2003-10-15 Publication of ATE251117T1 publication Critical patent/ATE251117T1/de

Links

229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 3
150000002431 hydrogen Chemical group 0.000 abstract 3
125000001424 substituent group Chemical group 0.000 abstract 3
239000002253 acid Substances 0.000 abstract 2
150000007513 acids Chemical class 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
125000004414 alkyl thio group Chemical group 0.000 abstract 2
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000004122 cyclic group Chemical group 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical group 0.000 abstract 2
-1 hydroxy, mercapto Chemical group 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
125000003282 alkyl amino group Chemical group 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
150000004677 hydrates Chemical class 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
231100000252 nontoxic Toxicity 0.000 abstract 1
230000003000 nontoxic effect Effects 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/22—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Physical Education & Sports Medicine (AREA)
Immunology (AREA)
Virology (AREA)
Orthopedic Medicine & Surgery (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pain & Pain Management (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Ophthalmology & Optometry (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT00943698T 1999-07-16 2000-07-11 Neue aminobenzophenone ATE251117T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US14406599P	1999-07-16	1999-07-16
PCT/DK2000/000384 WO2001005744A1 (en)	1999-07-16	2000-07-11	Novel aminobenzophenones

Publications (1)

Publication Number	Publication Date
ATE251117T1 true ATE251117T1 (de)	2003-10-15

Family

ID=22506899

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00943698T ATE251117T1 (de)	1999-07-16	2000-07-11	Neue aminobenzophenone

Country Status (18)

Country	Link
US (1)	US6624199B1 (de)
EP (1)	EP1202954B1 (de)
JP (1)	JP2003505359A (de)
KR (1)	KR20020013961A (de)
CN (1)	CN1231459C (de)
AT (1)	ATE251117T1 (de)
AU (1)	AU768473B2 (de)
CA (1)	CA2379316A1 (de)
DE (1)	DE60005689T2 (de)
DK (1)	DK1202954T3 (de)
ES (1)	ES2204639T3 (de)
HK (1)	HK1048304B (de)
HU (1)	HUP0201910A3 (de)
NZ (1)	NZ516824A (de)
PL (1)	PL353645A1 (de)
PT (1)	PT1202954E (de)
RU (1)	RU2243964C2 (de)
WO (1)	WO2001005744A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MXPA02005604A (es) *	1999-12-06	2004-09-10	Leo Pharma As	Aminobenzofenonas como inhibidores de il-1beta y tnf-alfa.
AU2001260081B2 (en)	2000-05-22	2005-07-28	Leo Pharma A/S	Benzophenones as inhibitors of il-1beta and tnf-alpha
GB0107368D0 (en) *	2001-03-23	2001-05-16	Novartis Ag	Organic compounds
AU2002333193A1 (en) *	2001-08-15	2003-03-03	Leo Pharma A/S	A pharmaceutical composition for dermal application
KR100896667B1 (ko)	2001-08-28	2009-05-14	레오 파마 에이/에스	신규한 아미노벤조페논 및 이를 포함하는 약제학적 조성물
US20030225089A1 (en) *	2002-04-10	2003-12-04	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Pharmaceutical compositions based on anticholinergics and p38 kinase inhibitors
DE60310730T2 (de)	2002-07-09	2007-05-16	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Pharmazeutische zusammensetzungen aus anticholinergica und p38 kinase hemmern zur behandlung von erkrankungen der atemwege
DK1658263T3 (da) *	2003-07-24	2010-09-27	Leo Pharma As	Aminobenzophenonforbindelser
WO2005110422A2 (en)	2004-05-19	2005-11-24	Boehringer Ingelheim International Gmbh	Treatment of diseases associated with altered level of amyloid beta peptides
US20060035893A1 (en)	2004-08-07	2006-02-16	Boehringer Ingelheim International Gmbh	Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
KR101260236B1 (ko)	2004-12-13	2013-05-06	레오 파마 에이/에스	트리아졸 치환된 아미노벤조페논 화합물
PE20060777A1 (es)	2004-12-24	2006-10-06	Boehringer Ingelheim Int	Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
FR2894821B1 (fr) *	2005-12-15	2008-02-29	Galderma Res & Dev	Compositions comprenant au moins un compose retinoide et au moins un compose anti-irritant et leurs utilisations
EP1992344A1 (de)	2007-05-18	2008-11-19	Institut Curie	P38 Alpha als therapeutisches Target für Erkrankungen, die mit einer FGFR3- Mutation assoziiert sind
EP2206534A1 (de)	2008-10-09	2010-07-14	c-a-i-r biosciences GmbH	Dibenzocycloheptanonderivate und pharmazeutische Mittel, welche diese Verbindungen enthalten

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9701453D0 (en)	1997-01-24	1997-03-12	Leo Pharm Prod Ltd	Aminobenzophenones

2000
- 2000-07-11 AU AU58067/00A patent/AU768473B2/en not_active Ceased
- 2000-07-11 NZ NZ516824A patent/NZ516824A/en unknown
- 2000-07-11 HU HU0201910A patent/HUP0201910A3/hu unknown
- 2000-07-11 WO PCT/DK2000/000384 patent/WO2001005744A1/en not_active Ceased
- 2000-07-11 CN CNB008115028A patent/CN1231459C/zh not_active Expired - Fee Related
- 2000-07-11 RU RU2002103862/04A patent/RU2243964C2/ru not_active IP Right Cessation
- 2000-07-11 DK DK00943698T patent/DK1202954T3/da active
- 2000-07-11 EP EP00943698A patent/EP1202954B1/de not_active Expired - Lifetime
- 2000-07-11 DE DE60005689T patent/DE60005689T2/de not_active Expired - Fee Related
- 2000-07-11 US US10/030,965 patent/US6624199B1/en not_active Expired - Fee Related
- 2000-07-11 KR KR1020027000669A patent/KR20020013961A/ko not_active Ceased
- 2000-07-11 PL PL00353645A patent/PL353645A1/xx not_active Application Discontinuation
- 2000-07-11 AT AT00943698T patent/ATE251117T1/de not_active IP Right Cessation
- 2000-07-11 PT PT00943698T patent/PT1202954E/pt unknown
- 2000-07-11 CA CA002379316A patent/CA2379316A1/en not_active Abandoned
- 2000-07-11 JP JP2001511405A patent/JP2003505359A/ja active Pending
- 2000-07-11 ES ES00943698T patent/ES2204639T3/es not_active Expired - Lifetime
- 2000-07-11 HK HK03100579.6A patent/HK1048304B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2379316A1 (en)	2001-01-25
DK1202954T3 (da)	2004-02-09
HK1048304B (zh)	2006-04-21
JP2003505359A (ja)	2003-02-12
HUP0201910A2 (hu)	2002-12-28
US6624199B1 (en)	2003-09-23
AU768473B2 (en)	2003-12-11
RU2243964C2 (ru)	2005-01-10
DE60005689T2 (de)	2004-08-05
PL353645A1 (en)	2003-12-01
DE60005689D1 (de)	2003-11-06
PT1202954E (pt)	2004-02-27
HUP0201910A3 (en)	2006-03-28
WO2001005744A1 (en)	2001-01-25
ES2204639T3 (es)	2004-05-01
EP1202954B1 (de)	2003-10-01
CN1368950A (zh)	2002-09-11
NZ516824A (en)	2004-03-26
EP1202954A1 (de)	2002-05-08
AU5806700A (en)	2001-02-05
CN1231459C (zh)	2005-12-14
HK1048304A1 (en)	2003-03-28
KR20020013961A (ko)	2002-02-21

Legal Events

Date

Code

Title

Description

2004-05-15

UEP

Publication of translation of european patent specification

Ref document number: 1202954

Country of ref document: EP

2008-04-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE251117T1 (de)	2003-10-15	Neue aminobenzophenone
DE60112974D1 (en)	2005-09-29	Carbolinderivate
TWI266761B (en)	2006-11-21	Benzoylsulfonamides and sulfonylbenzamidines for use as antitumour agents
TW364903B (en)	1999-07-21	Halogenopyrimidines
TW328086B (en)	1998-03-11	Biphenylamides, compositions comprising them and the preparation and use thereof
GB9801690D0 (en)	1998-03-25	Therapeutic agents
WO2003106428A8 (fr)	2004-05-06	Derives d'arylsulfonamides et leur utilisation en tant que antagonistes au recepteur b1 de la bradykinine
DE60014393D1 (de)	2004-11-04	Aminobenzophenone als inhibitoren von il-1beta und tnf-alpha
MXPA02012076A (es)	2003-06-06	Compuestos quimicos.
DE60216233D1 (en)	2007-01-04	Carbolinderivate
MXPA02012659A (es)	2003-09-22	Derivados de pirazindiona condensados.
MXPA03002911A (es)	2003-09-10	Compuestos quimicos.
MXPA03009750A (es)	2004-06-30	Compuestos quimicos.
DE60022227D1 (de)	2005-09-29	2-(1h-indol-3-yl)-2-oxo-acetamide mit antitumoraler wirkung
PT1021405E (pt)	2003-02-28	Derivados de azetidinona para o tratamento de infeccoes de hcmv
AP2002002466A0 (en)	2002-06-30	3-heterocycliylpropanohydroxamic acid PCP INHIBITORS.
MXPA02012470A (es)	2004-01-26	Inhibidores de fosfodiesterasa especificos para gmp ciclico.
MXPA02012472A (es)	2004-01-26	Compuestos quimicos.
IL166164A0 (en)	2006-01-15	6-amino-1h-indazole and 4-aminobenzofuran compounds as phosphodiesterase 4 inhibitors
MXPA03003971A (es)	2004-02-12	Derivados de indol como inhibidores de pde5.
NO994104D0 (no)	1999-08-25	5-hydroksymetyl-2-aminotetraliner i form av kardiovaskulaere midler
MXPA03000887A (es)	2004-04-05	Derivados heterociclicos fusionados como inhibidores de fosfodiesterasa.
BR9902096A (pt)	2000-04-11	Pitazóis.
DK1011679T3 (da)	2003-11-24	Anvendelse af 8-nitro-2,3,4,5-tetrahydro-1H-3-benzazepiner til fremstilling af en farmaceutisk sammensætning til behandling af søvnforstyrrelser
GB0427491D0 (en)	2005-01-19	Process and compounds