DK1011679T3 - Anvendelse af 8-nitro-2,3,4,5-tetrahydro-1H-3-benzazepiner til fremstilling af en farmaceutisk sammensætning til behandling af søvnforstyrrelser - Google Patents

Anvendelse af 8-nitro-2,3,4,5-tetrahydro-1H-3-benzazepiner til fremstilling af en farmaceutisk sammensætning til behandling af søvnforstyrrelser

Info

Publication number: DK1011679T3
Authority: DK; Denmark
Prior art keywords: treatment; pharmaceutical composition; bridge; hydrogen; sleep disorders
Prior art date: 1997-03-12

Application number

DK98907896T

Other languages

English (en)

Inventor

Anders Fink-Jensen

Christian Foged

Original Assignee

Addex Pharmaceuticals Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-03-12

Filing date

1998-03-11

Publication date

2003-11-24

1998-03-11 Application filed by Addex Pharmaceuticals Sa filed Critical Addex Pharmaceuticals Sa

2003-11-24 Application granted granted Critical

2003-11-24 Publication of DK1011679T3 publication Critical patent/DK1011679T3/da

Links

208000019116 sleep disease Diseases 0.000 title abstract 3
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
TXJXCXSFIVCGDS-UHFFFAOYSA-N 34583-83-0 Chemical class C1CNCCC2=CC([N+](=O)[O-])=CC=C21 TXJXCXSFIVCGDS-UHFFFAOYSA-N 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 3
150000002431 hydrogen Chemical group 0.000 abstract 3
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
208000022925 sleep disturbance Diseases 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK98907896T 1997-03-12 1998-03-11 Anvendelse af 8-nitro-2,3,4,5-tetrahydro-1H-3-benzazepiner til fremstilling af en farmaceutisk sammensætning til behandling af søvnforstyrrelser DK1011679T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DK26597		1997-03-12
US4150997P	1997-03-24	1997-03-24
PCT/DK1998/000088 WO1998040072A1 (en)	1997-03-12	1998-03-11	Use of 2,3,4,5-tetrahydro-1h-3-benzazepines for the manufacture of a pharmaceutical composition for the treatment of sleep disorders

Publications (1)

Publication Number	Publication Date
DK1011679T3 true DK1011679T3 (da)	2003-11-24

Family

ID=26063641

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98907896T DK1011679T3 (da)	1997-03-12	1998-03-11	Anvendelse af 8-nitro-2,3,4,5-tetrahydro-1H-3-benzazepiner til fremstilling af en farmaceutisk sammensætning til behandling af søvnforstyrrelser

Country Status (16)

Country	Link
US (1)	US6211173B1 (da)
EP (1)	EP1011679B1 (da)
JP (1)	JP2001515484A (da)
AT (1)	ATE245986T1 (da)
AU (1)	AU742873B2 (da)
BR (1)	BR9808234A (da)
CA (1)	CA2283083C (da)
CZ (1)	CZ296464B6 (da)
DE (1)	DE69816832T2 (da)
DK (1)	DK1011679T3 (da)
ES (1)	ES2203933T3 (da)
IL (1)	IL131670A (da)
NO (1)	NO324719B1 (da)
PL (1)	PL189822B1 (da)
PT (1)	PT1011679E (da)
WO (1)	WO1998040072A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1646623A2 (en) *	2003-05-22	2006-04-19	Schering Corporation	5-h-benzo[d]naphth[2,1-b]azepine derivative as selective d1/d5 receptor antagonists for the treatment of obesity and cns disorders
PT1691811E (pt) *	2003-12-11	2014-10-30	Sunovion Pharmaceuticals Inc	Combinação de um sedativo e de um modulador de neurotransmissores e métodos para melhorar a qualidade do sono e tratamento da depressão
US20050215521A1 (en) *	2003-12-22	2005-09-29	Karim Lalji	Modafinil combination therapy for improving sleep quality
EP1696959A2 (en) *	2003-12-24	2006-09-06	Sepracor, Inc.	Melatonin combination therapy for improving sleep quality
ATE454140T1 (de) *	2004-02-18	2010-01-15	Sepracor Inc	Dopamin-agonisten-kombinationstherapie mit sedativa zur verbesserung der schlafqualität

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK325188D0 (da)	1988-06-15	1988-06-15	Novo Industri As	Hidtil ukendte benzazepinderivater
US5470850A (en)	1992-02-24	1995-11-28	Novo Nordisk A/S	2,3,4,5-tetrahydro-1H-3-benzazepines
DK26793D0 (da)	1993-03-10	1993-03-10	Novo Nordisk As	Benzofuranyl- eller dihydrobenzofuranyl-substituerede tricycliske benzazepiner, der anvendelse og fremstilling

1998
- 1998-03-11 IL IL13167098A patent/IL131670A/xx not_active IP Right Cessation
- 1998-03-11 PL PL98335545A patent/PL189822B1/pl not_active IP Right Cessation
- 1998-03-11 AU AU66100/98A patent/AU742873B2/en not_active Ceased
- 1998-03-11 DK DK98907896T patent/DK1011679T3/da active
- 1998-03-11 CA CA002283083A patent/CA2283083C/en not_active Expired - Fee Related
- 1998-03-11 BR BR9808234-5A patent/BR9808234A/pt not_active Application Discontinuation
- 1998-03-11 WO PCT/DK1998/000088 patent/WO1998040072A1/en not_active Ceased
- 1998-03-11 AT AT98907896T patent/ATE245986T1/de active
- 1998-03-11 PT PT98907896T patent/PT1011679E/pt unknown
- 1998-03-11 DE DE69816832T patent/DE69816832T2/de not_active Expired - Lifetime
- 1998-03-11 JP JP53910298A patent/JP2001515484A/ja not_active Ceased
- 1998-03-11 CZ CZ0317799A patent/CZ296464B6/cs not_active IP Right Cessation
- 1998-03-11 ES ES98907896T patent/ES2203933T3/es not_active Expired - Lifetime
- 1998-03-11 US US09/380,840 patent/US6211173B1/en not_active Expired - Fee Related
- 1998-03-11 EP EP98907896A patent/EP1011679B1/en not_active Expired - Lifetime
1999
- 1999-09-07 NO NO19994343A patent/NO324719B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
CZ296464B6 (cs)	2006-03-15
PT1011679E (pt)	2003-12-31
IL131670A0 (en)	2001-01-28
DE69816832T2 (de)	2004-05-27
CA2283083C (en)	2007-09-04
EP1011679A1 (en)	2000-06-28
PL189822B1 (pl)	2005-09-30
US6211173B1 (en)	2001-04-03
WO1998040072A1 (en)	1998-09-17
PL335545A1 (en)	2000-04-25
ATE245986T1 (de)	2003-08-15
AU742873B2 (en)	2002-01-17
IL131670A (en)	2005-07-25
CZ317799A3 (cs)	2000-03-15
BR9808234A (pt)	2000-05-16
NO994343D0 (no)	1999-09-07
NO994343L (no)	1999-11-11
JP2001515484A (ja)	2001-09-18
ES2203933T3 (es)	2004-04-16
NO324719B1 (no)	2007-12-03
CA2283083A1 (en)	1998-09-17
AU6610098A (en)	1998-09-29
EP1011679B1 (en)	2003-07-30
DE69816832D1 (de)	2003-09-04

Similar Documents

Publication	Publication Date	Title
TW347387B (en)	1998-12-11	Piperidine derivatives
TW328086B (en)	1998-03-11	Biphenylamides, compositions comprising them and the preparation and use thereof
AP2003002841A0 (en)	2003-09-30	Quinazolines as MMP-13 inhibitors
JO2321B1 (en)	2005-09-12	4-phenyl-pyridine derivatives
ATE155465T1 (de)	1997-08-15	Phenoxy- oder phenoxyalkyl-piperidine als antivirale mittel
FR2712591B1 (fr)	1996-02-09	Nouvelles arylpipérazines dérivées d'indole, leur préparation et leur utilisation thérapeutique.
NZ514542A (en)	2002-10-25	Vasopressin antagonists for the treatment of pulmonary hypertension
HUP0204354A2 (hu)	2003-04-28	Új heterociklusos vegyületek, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk
ID26622A (id)	2001-01-25	Senyawa-senyawa pengganti 2-benzylamino-2-phenyl-acetamide
DE60005689D1 (de)	2003-11-06	Neue aminobenzophenone
DE60121048D1 (de)	2006-08-03	PYRAZINOi1'2':1,6öPYRIDOi3,4-BöINDOLDERIVATE
NO994343D0 (no)	1999-09-07	Anvendelse av 2,3,4,5 - tetrahydro- 1H-3-benzazepiner for fremstilling av en farmasöytisk blanding for behandlingen av soveuregelmessigheter
DE69402935D1 (de)	1997-06-05	Substituierte arylalkylaminobenzyl-aminopropanamide, ihre herstellung und verwendung als antiepileptische, neuroprotektive und antidepressive mittel
DK1068184T3 (da)	2002-12-30	N-aryloxyethylaminderivater til behandling af despression
DK0970042T3 (da)	2002-04-29	5-hydroxymethyl-2-aminotetraliner som kardiovaskulære midler
NO973340L (no)	1997-07-18	Anvendelse av 3,4-difenylkromaner til fremstilling av et farmasöytisk preparat for behandling eller profylakse av fedme
TR200001926T2 (tr)	2000-11-21	Vasküler başağrılarına karşı lokal anesteziklerin yeni kullanımı
ATE158301T1 (de)	1997-10-15	4-aza-pregnan-5-alpha-reductase isozym 1 inhibitoren
ATE202108T1 (de)	2001-06-15	Cephemverbindungen
TR199801683A2 (xx)	1999-03-22	Yeni �re t�revleri.
PT900082E (pt)	2002-04-29	Utilizacao de piridilpiperazina e pirimidilpiperazina para o fabrico de um medicamento para o tratamento de perturbacoes de toxicomania
SE9603284D0 (sv)	1996-09-10	New compounds
ATE136029T1 (de)	1996-04-15	Carbostyrylderivate
PT1140919E (pt)	2002-12-31	Novos derivados de ciclohexano 1,4-dissubstituido para o tratamento da depressao
MX9705218A (es)	1997-10-31	Uso de los 3,4-difenil-cromanos para la fabricacion de una composicion farmaceutica para el tratamiento o profilaxis de ginecomastia idiopatica o fisiologica.