ATE251157T1 - Bicyclische aminderivate - Google Patents

Bicyclische aminderivate

Info

Publication number
ATE251157T1
ATE251157T1 AT93120802T AT93120802T ATE251157T1 AT E251157 T1 ATE251157 T1 AT E251157T1 AT 93120802 T AT93120802 T AT 93120802T AT 93120802 T AT93120802 T AT 93120802T AT E251157 T1 ATE251157 T1 AT E251157T1
Authority
AT
Austria
Prior art keywords
substituent
atom
amine derivatives
bicyclic amine
hydrogen atom
Prior art date
Application number
AT93120802T
Other languages
English (en)
Inventor
Makoto C O Daiichi Ph Takemura
-Chome Kitakasai
Youichi C O Daiichi Pha Kimura
Norikazu C O Daiich Matsuhashi
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Application granted granted Critical
Publication of ATE251157T1 publication Critical patent/ATE251157T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT93120802T 1992-12-25 1993-12-23 Bicyclische aminderivate ATE251157T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP34603092 1992-12-25

Publications (1)

Publication Number Publication Date
ATE251157T1 true ATE251157T1 (de) 2003-10-15

Family

ID=18380663

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93120802T ATE251157T1 (de) 1992-12-25 1993-12-23 Bicyclische aminderivate

Country Status (17)

Country Link
US (1) US5654318A (de)
EP (1) EP0603887B1 (de)
JP (1) JP3268098B2 (de)
KR (1) KR100295483B1 (de)
CN (1) CN1037441C (de)
AT (1) ATE251157T1 (de)
AU (1) AU669948B2 (de)
CA (1) CA2112165C (de)
DE (1) DE69333223T2 (de)
DK (1) DK0603887T3 (de)
ES (1) ES2208636T3 (de)
FI (1) FI105031B (de)
NO (1) NO301165B1 (de)
PH (1) PH31587A (de)
PT (1) PT603887E (de)
RU (1) RU2125046C1 (de)
TW (1) TW264476B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0148277B1 (ko) * 1993-01-18 1998-11-02 채영복 신규한 플루오르퀴놀론계 유도체 및 그의 제조방법
KR960004339A (ko) * 1994-07-02 1996-02-23 임성기 신규한 퀴놀린계 화합물 및 그 의 제조방법
WO1996011194A1 (en) * 1994-10-06 1996-04-18 Dainippon Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivative and intermediate for the synthesis of the same
DE19546249A1 (de) * 1995-12-12 1997-06-19 Bayer Ag Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
EP0882049B1 (de) * 1996-02-23 2002-11-20 Bayer Ag Gegebenenfalls substituierte 8-cyan-1-cyclopropyl-7-(2,8-diazabicyclo- 4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre derivate
ATE209651T1 (de) * 1996-02-27 2001-12-15 Dainippon Pharmaceutical Co Pyridoncarbonsäure-derivate und zwischenverbindungen für deren herstellung
US6384050B1 (en) * 1996-10-25 2002-05-07 Daiichi Pharmaceutical Co., Ltd. Tricyclic amine derivatives
DE19652239A1 (de) * 1996-12-16 1998-06-18 Bayer Ag Verwendung von 7-(2-Oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-chinolon- und -naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen
DE19821039A1 (de) * 1998-05-11 1999-11-18 Bayer Ag Verfahren zur Herstellung von (S,S)-Benzyl-2,8-diazabicyclo[4.3.0]nonan
DE19931115A1 (de) * 1999-07-06 2001-01-11 Bayer Ag Racemisierung von R, S-Dioxo-Benzylpyrrolopiperidin
ATE407121T1 (de) * 2000-02-09 2008-09-15 Daiichi Sankyo Co Ltd Gegen säurebeständige bakterien wirksame antibakterielle mittel die pyridincarbonsäuren als aktiven wirkstoff enthalten
MY137020A (en) 2000-04-27 2008-12-31 Abbott Lab Diazabicyclic central nervous system active agents
US6809105B2 (en) 2000-04-27 2004-10-26 Abbott Laboratories Diazabicyclic central nervous system active agents
DE10022369A1 (de) 2000-05-08 2001-11-15 Bayer Ag Verfahren zur Herstellung von Piperidinen
US7906649B2 (en) * 2005-05-25 2011-03-15 Merck Sharp & Dohme Corp. Aminocyclohexanes as dipeptidyl peptidase-IV inhibitors for the treatment of diabetes
CN102101861B (zh) * 2008-07-01 2012-07-18 韶远化学科技（上海）有限公司 含氮双杂环医药中间体的合成及工艺方法
CA2762022A1 (en) 2009-05-15 2010-11-18 Redx Pharma Limited Redox drug derivatives
CN102675308A (zh) * 2011-03-17 2012-09-19 苏州中科天马肽工程中心有限公司 一种制备8-苄基-2,8-二氮杂二环[4.3.0]壬烷的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT294090B (de) * 1969-04-22 1971-11-10 Degussa Verfahren zur Herstellung von neuen Aminopyridinen, von deren optisch aktiven bzw. diastereomeren Formen, deren Salzen und deren quartären Verbindungen
NZ210805A (en) * 1984-01-19 1988-04-29 Norton Co Aluminous abrasive grits or shaped bodies
JPS6212760A (ja) * 1984-12-14 1987-01-21 Dai Ichi Seiyaku Co Ltd １−（２−ハロゲノシクロプロピル）キノリンカルボン酸誘導体
DE3509546A1 (de) * 1985-03-16 1986-09-25 Bayer Ag, 5090 Leverkusen 7-amino-1-(subst.cyclopropyl)-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
MY105136A (en) * 1988-04-27 1994-08-30 Daiichi Seiyaku Co Optically active pyridonecarboxylic acid derivatives.
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
KR910009330B1 (ko) * 1989-10-23 1991-11-11 재단법인 한국화학연구소 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법
CA2030217A1 (en) * 1989-11-21 1991-05-22 Jun Imose Pyridone-carboxylic acid derivatives useful as veterinary medicines
JPH03188080A (ja) * 1989-12-15 1991-08-16 Banyu Pharmaceut Co Ltd ピリドンカルボン酸誘導体
DE4032560A1 (de) * 1990-10-13 1992-04-16 Bayer Ag 7-(2,7-diazabicyclo(3.3.0)octyl)-3-chinolon- und -naphtyridoncarbonsaeure-derivate
US5696132A (en) * 1991-05-28 1997-12-09 Daiichi Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivatives
TW209865B (de) * 1992-01-10 1993-07-21 Bayer Ag
DE4230804A1 (de) * 1992-09-15 1994-03-17 Bayer Ag 7-Isoindolinyl-chinolon- und -naphthyridon-Derivate

Also Published As

Publication number Publication date
PH31587A (en) 1998-11-03
KR100295483B1 (ko) 2001-09-17
US5654318A (en) 1997-08-05
EP0603887A2 (de) 1994-06-29
NO934753L (no) 1994-06-27
CN1037441C (zh) 1998-02-18
CA2112165C (en) 2003-04-08
DE69333223D1 (de) 2003-11-06
CA2112165A1 (en) 1994-06-26
DK0603887T3 (da) 2004-01-26
FI105031B (fi) 2000-05-31
TW264476B (de) 1995-12-01
AU5269593A (en) 1994-07-07
EP0603887A3 (de) 1995-04-26
DE69333223T2 (de) 2004-08-05
CN1095068A (zh) 1994-11-16
PT603887E (pt) 2004-02-27
NO934753D0 (no) 1993-12-22
KR940014397A (ko) 1994-07-18
RU2125046C1 (ru) 1999-01-20
FI935830L (fi) 1994-06-26
AU669948B2 (en) 1996-06-27
NO301165B1 (no) 1997-09-22
FI935830A0 (fi) 1993-12-23
JP3268098B2 (ja) 2002-03-25
JPH06239857A (ja) 1994-08-30
EP0603887B1 (de) 2003-10-01
ES2208636T3 (es) 2004-06-16

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