DK1262477T3 - Antibakterielle midler, der er virksomme mod syrefaste bakterier og indeholder pyridoncarboxylsyrer som aktiv ingrediens - Google Patents
Antibakterielle midler, der er virksomme mod syrefaste bakterier og indeholder pyridoncarboxylsyrer som aktiv ingrediensInfo
- Publication number
- DK1262477T3 DK1262477T3 DK01904335T DK01904335T DK1262477T3 DK 1262477 T3 DK1262477 T3 DK 1262477T3 DK 01904335 T DK01904335 T DK 01904335T DK 01904335 T DK01904335 T DK 01904335T DK 1262477 T3 DK1262477 T3 DK 1262477T3
- Authority
- DK
- Denmark
- Prior art keywords
- active ingredient
- contain
- carboxylic acids
- antibacterial agents
- effective against
- Prior art date
Links
- 241000894006 Bacteria Species 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 239000003242 anti bacterial agent Substances 0.000 title 1
- -1 pyridone carboxylic acids Chemical class 0.000 title 1
- YSLIPUSJNFIFAB-UHFFFAOYSA-N 2-oxopyridine-1-carboxylic acid Chemical class OC(=O)N1C=CC=CC1=O YSLIPUSJNFIFAB-UHFFFAOYSA-N 0.000 abstract 1
- 241000187479 Mycobacterium tuberculosis Species 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Jellies, Jams, And Syrups (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000038099 | 2000-02-09 | ||
| PCT/JP2001/000861 WO2001058876A1 (en) | 2000-02-09 | 2001-02-07 | Anti-acid-fast bacterial agents containing pyridonecarboxylic acids as the active ingredient |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1262477T3 true DK1262477T3 (da) | 2008-12-01 |
Family
ID=18561886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01904335T DK1262477T3 (da) | 2000-02-09 | 2001-02-07 | Antibakterielle midler, der er virksomme mod syrefaste bakterier og indeholder pyridoncarboxylsyrer som aktiv ingrediens |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7176313B2 (da) |
| EP (1) | EP1262477B1 (da) |
| KR (1) | KR100817425B1 (da) |
| CN (1) | CN1312131C (da) |
| AT (1) | ATE407121T1 (da) |
| AU (2) | AU3223801A (da) |
| CA (1) | CA2398988C (da) |
| DE (1) | DE60135640D1 (da) |
| DK (1) | DK1262477T3 (da) |
| ES (1) | ES2312411T3 (da) |
| HK (1) | HK1048118B (da) |
| IL (2) | IL151035A0 (da) |
| MX (1) | MXPA02007667A (da) |
| NO (1) | NO325656B1 (da) |
| PT (1) | PT1262477E (da) |
| RU (2) | RU2299205C2 (da) |
| TW (1) | TWI283668B (da) |
| WO (1) | WO2001058876A1 (da) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002236267A1 (en) * | 2002-03-08 | 2003-09-22 | Daiichi Pharmaceutical Co., Ltd. | Quinolonecarboxylic acid derivative |
| US7459005B2 (en) | 2002-11-22 | 2008-12-02 | Akzo Nobel N.V. | Chemical composition and method |
| DE10314634A1 (de) * | 2003-04-01 | 2004-10-14 | Khs Maschinen- Und Anlagenbau Ag, Patentabteilung | Spülbares Huborgan |
| PL1666477T3 (pl) | 2003-09-10 | 2013-11-29 | Kyorin Seiyaku Kk | Pochodna kwasu 7-(4-podstawionego-3-cyklopropyloaminometylo-1- pirolidynylo)chinolonokarboksylowego |
| WO2005030752A1 (ja) * | 2003-09-29 | 2005-04-07 | Daiichi Pharmaceutical Co., Ltd. | ８−シアノキノロンカルボン酸誘導体 |
| ITMI20032259A1 (it) * | 2003-11-20 | 2005-05-21 | Chemi Spa | Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione |
| TW200640899A (en) * | 2005-01-21 | 2006-12-01 | Daiichi Seiyaku Co | Fluoroalkylpyrrolidine derivative |
| US8129533B2 (en) | 2005-09-28 | 2012-03-06 | Dalichi Sankyo Company, Limited | Method for production of quinolone-containing lyophilized preparation |
| JP5174365B2 (ja) * | 2007-03-23 | 2013-04-03 | 第一三共株式会社 | キノロン含有凍結乾燥製剤の製造方法 |
| RU2318513C1 (ru) * | 2007-04-10 | 2008-03-10 | Автономная некоммерческая организация "Институт молекулярной диагностики" (АНО "ИнМоДи") | Лекарственное средство на основе d-циклосерина, препарат пролонгированного действия, содержащий наночастицы, способ его получения |
| JP5322927B2 (ja) * | 2007-05-24 | 2013-10-23 | 杏林製薬株式会社 | １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体 |
| CA2727651C (en) * | 2008-06-17 | 2016-04-05 | Priscille Brodin | Anti-infective compounds |
| BRPI1010981A2 (pt) | 2009-05-15 | 2018-12-04 | Redx Pharma Ltd | "derivados de fármaco redox" |
| KR20130088002A (ko) * | 2010-01-13 | 2013-08-07 | 재단법인 한국파스퇴르연구소 | 항-감염성 피리도(1,2-ａ)피리미딘 |
| WO2014152332A1 (en) | 2013-03-15 | 2014-09-25 | Melinta Therapeutics, Inc. | Methods of treating infections in overweight and obese patients using antibiotics |
| CN103381169A (zh) * | 2013-07-04 | 2013-11-06 | 丁圣雨 | Chukrasone A在抗结核菌药物中的应用 |
| KR20230085439A (ko) | 2021-12-07 | 2023-06-14 | 대한민국(국립마산병원장) | 비결핵 항산균 감염 질환의 예방 또는 치료용 조성물 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5872589A (ja) * | 1981-10-28 | 1983-04-30 | Dai Ichi Seiyaku Co Ltd | ピリド〔１，２，３−ｄｅ〕〔１，４〕ベンゾオキサジン誘導体 |
| EP0191185B1 (en) | 1984-12-14 | 1990-03-07 | Daiichi Seiyaku Co., Ltd. | Quinoline-carboxylic acid derivatives |
| JPS61205258A (ja) * | 1985-03-08 | 1986-09-11 | Kyorin Pharmaceut Co Ltd | キノロンカルボン酸誘導体及びその製造方法 |
| US4977154A (en) | 1985-12-12 | 1990-12-11 | Warner-Lambert Company | 5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents |
| JPH089597B2 (ja) | 1986-01-21 | 1996-01-31 | 杏林製薬株式会社 | 選択毒性に優れた８‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法 |
| DE3705621C2 (de) * | 1986-02-25 | 1997-01-09 | Otsuka Pharma Co Ltd | Heterocyclisch substituierte Chinoloncarbonsäurederivate |
| US4777253A (en) | 1986-04-25 | 1988-10-11 | Abbott Laboratories | Process for preparation of racemate and optically active ofloxacin and related derivatives |
| NO885426L (no) * | 1987-12-11 | 1989-06-12 | Dainippon Pharmaceutical Co | Kinolinderivater, samt fremgangsmaate ved fremstilling derav. |
| IL90062A (en) | 1988-04-27 | 1994-10-07 | Daiichi Seiyaku Co | Pyridonecarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them |
| EP0341439B1 (en) | 1988-05-11 | 1993-08-04 | Abbott Laboratories | Method for increasing specificity in competitive immunoassays |
| DE3906365A1 (de) * | 1988-07-15 | 1990-01-18 | Bayer Ag | 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe |
| FI95130C (fi) * | 1988-07-20 | 1995-12-27 | Sankyo Co | Menetelmä lääkeaineena käyttökelpoisten 4-oksokinoliini-3-karboksyylihapon johdannaisten valmistamiseksi |
| CA1336090C (en) | 1988-08-31 | 1995-06-27 | Isao Hayakawa | Spiro-substituted cyclic amines of quinolone derivatives |
| JP3026162B2 (ja) | 1988-08-31 | 2000-03-27 | 第一製薬株式会社 | スピロ化合物 |
| JPH0324013A (ja) * | 1989-06-21 | 1991-02-01 | Kyowa Hakko Kogyo Co Ltd | 抗腫瘍剤 |
| JPH0381224A (ja) | 1989-08-22 | 1991-04-05 | Otsuka Pharmaceut Co Ltd | ライ病治療剤 |
| DE4120646A1 (de) * | 1991-06-22 | 1992-12-24 | Bayer Ag | 7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate |
| US6075024A (en) * | 1991-11-27 | 2000-06-13 | Sepracor Inc. | Methods for treating infection using optically pure (S)-lomefloxacin |
| NO304832B1 (no) * | 1992-05-27 | 1999-02-22 | Ube Industries | Aminokinolonderivater samt middel mot HIV |
| JPH0649059A (ja) * | 1992-07-23 | 1994-02-22 | Hokuriku Seiyaku Co Ltd | ７−（５−アザスピロ〔２，４〕ヘプタン−５−イル）−８−アルコキシキノリン−３−カルボン酸誘導体 |
| CA2112165C (en) | 1992-12-25 | 2003-04-08 | Makoto Takemura | Bicyclic amine derivatives |
| JPH06271568A (ja) * | 1993-03-22 | 1994-09-27 | Hokuriku Seiyaku Co Ltd | ７−フェニルピペラジニルキノリン−３−カルボン酸誘導体 |
| TW252107B (da) | 1993-08-27 | 1995-07-21 | Hokuriku Pharmacetical Co Ltd | |
| WO2001062734A1 (en) * | 2000-02-25 | 2001-08-30 | Daiichi Pharmaceutical Co., Ltd. | Process for producing quinolonecarboxylic acids and intermediates thereof |
| RU2002135315A (ru) * | 2000-03-31 | 2004-05-27 | Дайити Фармасьютикал Ко.,Лтд. (Jp) | Производные хинолонкарбоновой кислоты |
-
2001
- 2001-02-07 AU AU3223801A patent/AU3223801A/xx active Pending
- 2001-02-07 RU RU2002121245/04A patent/RU2299205C2/ru not_active IP Right Cessation
- 2001-02-07 MX MXPA02007667A patent/MXPA02007667A/es active IP Right Grant
- 2001-02-07 WO PCT/JP2001/000861 patent/WO2001058876A1/ja not_active Ceased
- 2001-02-07 CN CNB018077331A patent/CN1312131C/zh not_active Expired - Fee Related
- 2001-02-07 DK DK01904335T patent/DK1262477T3/da active
- 2001-02-07 KR KR1020027010292A patent/KR100817425B1/ko not_active Expired - Fee Related
- 2001-02-07 EP EP01904335A patent/EP1262477B1/en not_active Expired - Lifetime
- 2001-02-07 DE DE60135640T patent/DE60135640D1/de not_active Expired - Lifetime
- 2001-02-07 HK HK03100293.1A patent/HK1048118B/en not_active IP Right Cessation
- 2001-02-07 AT AT01904335T patent/ATE407121T1/de active
- 2001-02-07 AU AU2001232238A patent/AU2001232238B2/en not_active Ceased
- 2001-02-07 PT PT01904335T patent/PT1262477E/pt unknown
- 2001-02-07 US US10/203,199 patent/US7176313B2/en not_active Expired - Fee Related
- 2001-02-07 RU RU2004137055/04A patent/RU2297420C2/ru not_active IP Right Cessation
- 2001-02-07 CA CA2398988A patent/CA2398988C/en not_active Expired - Fee Related
- 2001-02-07 ES ES01904335T patent/ES2312411T3/es not_active Expired - Lifetime
- 2001-02-07 IL IL15103501A patent/IL151035A0/xx unknown
- 2001-02-09 TW TW090102897A patent/TWI283668B/zh not_active IP Right Cessation
-
2002
- 2002-08-01 IL IL151035A patent/IL151035A/en not_active IP Right Cessation
- 2002-08-08 NO NO20023764A patent/NO325656B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2312411T3 (es) | 2009-03-01 |
| RU2297420C2 (ru) | 2007-04-20 |
| EP1262477A4 (en) | 2003-07-02 |
| CA2398988A1 (en) | 2001-08-16 |
| CN1312131C (zh) | 2007-04-25 |
| AU3223801A (en) | 2001-08-20 |
| HK1048118A1 (en) | 2003-03-21 |
| RU2299205C2 (ru) | 2007-05-20 |
| IL151035A0 (en) | 2003-04-10 |
| HK1048118B (en) | 2009-01-09 |
| RU2004137055A (ru) | 2006-05-27 |
| PT1262477E (pt) | 2008-11-14 |
| IL151035A (en) | 2008-12-29 |
| DE60135640D1 (de) | 2008-10-16 |
| WO2001058876A1 (en) | 2001-08-16 |
| EP1262477B1 (en) | 2008-09-03 |
| RU2002121245A (ru) | 2004-04-10 |
| KR20020074517A (ko) | 2002-09-30 |
| TWI283668B (en) | 2007-07-11 |
| CN1422256A (zh) | 2003-06-04 |
| US7176313B2 (en) | 2007-02-13 |
| MXPA02007667A (es) | 2003-04-14 |
| EP1262477A1 (en) | 2002-12-04 |
| US20030119848A1 (en) | 2003-06-26 |
| ATE407121T1 (de) | 2008-09-15 |
| AU2001232238B2 (en) | 2005-03-24 |
| NO20023764L (no) | 2002-10-09 |
| NO20023764D0 (no) | 2002-08-08 |
| NO325656B1 (no) | 2008-06-30 |
| CA2398988C (en) | 2010-06-22 |
| KR100817425B1 (ko) | 2008-03-27 |
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| Publication | Publication Date | Title |
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