ATE251626T1 - Verfahren zur herstellung von enantiomerreinen fluorierten epoxychromanen - Google Patents
Verfahren zur herstellung von enantiomerreinen fluorierten epoxychromanenInfo
- Publication number
- ATE251626T1 ATE251626T1 AT93904228T AT93904228T ATE251626T1 AT E251626 T1 ATE251626 T1 AT E251626T1 AT 93904228 T AT93904228 T AT 93904228T AT 93904228 T AT93904228 T AT 93904228T AT E251626 T1 ATE251626 T1 AT E251626T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrogen
- epoxychromans
- enantiomer pure
- pure fluorinated
- producing enantiomer
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- -1 polymethylene moiety Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/22—Organic complexes
- B01J31/2204—Organic complexes the ligands containing oxygen or sulfur as complexing atoms
- B01J31/2208—Oxygen, e.g. acetylacetonates
- B01J31/2226—Anionic ligands, i.e. the overall ligand carries at least one formal negative charge
- B01J31/2243—At least one oxygen and one nitrogen atom present as complexing atoms in an at least bidentate or bridging ligand
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
- B01J2231/70—Oxidation reactions, e.g. epoxidation, (di)hydroxylation, dehydrogenation and analogues
- B01J2231/72—Epoxidation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/02—Compositional aspects of complexes used, e.g. polynuclearity
- B01J2531/0238—Complexes comprising multidentate ligands, i.e. more than 2 ionic or coordinative bonds from the central metal to the ligand, the latter having at least two donor atoms, e.g. N, O, S, P
- B01J2531/0241—Rigid ligands, e.g. extended sp2-carbon frameworks or geminal di- or trisubstitution
- B01J2531/0252—Salen ligands or analogues, e.g. derived from ethylenediamine and salicylaldehyde
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/70—Complexes comprising metals of Group VII (VIIB) as the central metal
- B01J2531/72—Manganese
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Catalysts (AREA)
- Saccharide Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929203596A GB9203596D0 (en) | 1992-02-20 | 1992-02-20 | Novel process |
| PCT/GB1993/000344 WO1993017026A1 (en) | 1992-02-20 | 1993-02-18 | Process for preparing enantiomerically pure fluorinated epoxychromans |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE251626T1 true ATE251626T1 (de) | 2003-10-15 |
Family
ID=10710733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93904228T ATE251626T1 (de) | 1992-02-20 | 1993-02-18 | Verfahren zur herstellung von enantiomerreinen fluorierten epoxychromanen |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0626967B1 (de) |
| JP (1) | JPH07504183A (de) |
| KR (1) | KR100245205B1 (de) |
| AT (1) | ATE251626T1 (de) |
| AU (1) | AU675420B2 (de) |
| CA (1) | CA2130481A1 (de) |
| DE (1) | DE69333240T2 (de) |
| GB (1) | GB9203596D0 (de) |
| MX (1) | MX9300895A (de) |
| NZ (1) | NZ249200A (de) |
| WO (1) | WO1993017026A1 (de) |
| ZA (1) | ZA931133B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ546834A (en) | 2003-10-01 | 2010-03-26 | Adolor Corp | Spirocyclic heterocyclic derivatives and methods of their use |
| US7598261B2 (en) | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| US7576207B2 (en) | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL86798A (en) * | 1987-06-23 | 1992-12-01 | Sanofi Sa | 2,2-dimethylchroman-3-ol derivatives, their preparation and pharmaceutical compositions containing them |
| ATE120459T1 (de) * | 1988-12-13 | 1995-04-15 | Beecham Group Plc | Benzopyran und verwandte verbindungen. |
| AU648301B2 (en) * | 1990-03-21 | 1994-04-21 | Research Corporation Technologies, Inc. | Chiral catalysts and epoxidation reactions catalyzed thereby |
-
1992
- 1992-02-20 GB GB929203596A patent/GB9203596D0/en active Pending
-
1993
- 1993-02-18 AT AT93904228T patent/ATE251626T1/de not_active IP Right Cessation
- 1993-02-18 WO PCT/GB1993/000344 patent/WO1993017026A1/en not_active Ceased
- 1993-02-18 ZA ZA931133A patent/ZA931133B/xx unknown
- 1993-02-18 KR KR1019940702882A patent/KR100245205B1/ko not_active Expired - Fee Related
- 1993-02-18 NZ NZ249200A patent/NZ249200A/en unknown
- 1993-02-18 EP EP93904228A patent/EP0626967B1/de not_active Expired - Lifetime
- 1993-02-18 JP JP5514631A patent/JPH07504183A/ja active Pending
- 1993-02-18 CA CA002130481A patent/CA2130481A1/en not_active Abandoned
- 1993-02-18 AU AU35095/93A patent/AU675420B2/en not_active Ceased
- 1993-02-18 DE DE69333240T patent/DE69333240T2/de not_active Expired - Fee Related
- 1993-02-19 MX MX9300895A patent/MX9300895A/es not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0626967A1 (de) | 1994-12-07 |
| NZ249200A (en) | 1996-06-25 |
| EP0626967B1 (de) | 2003-10-08 |
| CA2130481A1 (en) | 1993-09-02 |
| GB9203596D0 (en) | 1992-04-08 |
| KR100245205B1 (ko) | 2000-03-02 |
| DE69333240T2 (de) | 2004-08-05 |
| WO1993017026A1 (en) | 1993-09-02 |
| KR950700306A (ko) | 1995-01-16 |
| ZA931133B (en) | 1994-06-03 |
| MX9300895A (es) | 1994-08-31 |
| AU675420B2 (en) | 1997-02-06 |
| DE69333240D1 (de) | 2003-11-13 |
| JPH07504183A (ja) | 1995-05-11 |
| AU3509593A (en) | 1993-09-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE59108707D1 (de) | Verfahren zur Herstellung von Oxetanonen | |
| ATE229960T1 (de) | Verfahren zur herstellung von 13-ether-derivaten von milbemycinen und zwischenprodukte | |
| EA199800490A1 (ru) | Полиамид, способ его получения и композиции, его содержащие | |
| DE59409435D1 (de) | Verfahren zur Herstellung von 3-Arylbenzofuranonen | |
| ATE174903T1 (de) | Neues verfahren zur herstellung von 7- (substituierten)-9-((substistuierter | |
| ATE121091T1 (de) | Phospholipase a2-inhibitor, mikroorganismen, die diesen inhibitor erzeugen und mehrere verfahren zu seiner herstellung. | |
| DE69001732D1 (de) | Verfahren zur enantioselektiven herstellung von phenylisoserin-derivaten. | |
| DE69411243D1 (de) | Verfahren zur herstellung eines lignan-derivats | |
| ATE184053T1 (de) | Verfahren zur herstellung von indolopyrrolocarbazolderivaten | |
| DE69106003D1 (de) | Verfahren und zwischenprodukte zur herstellung von azabicyclo[2.2.2]octan-3-iminen. | |
| ATE478055T1 (de) | Verfahren zur herstellung von monofunktionalisiertem 1,4,7,10- tetraazacyclododecan | |
| ATE251626T1 (de) | Verfahren zur herstellung von enantiomerreinen fluorierten epoxychromanen | |
| ATE156134T1 (de) | Verfahren zur herstellung von alkylpolyglukosiden | |
| DE69616719D1 (de) | Verfahren zur herstellung von taxol und seiner derivate | |
| ATE55382T1 (de) | Verfahren zur herstellung von optisch aktiven hydrochinonderivaten sowie von d-alphatocopherol. | |
| DE69211936D1 (de) | Verfahren zur Herstellung von niedrigem Alkyl-2-oxo-L-Gulonat | |
| DE59908429D1 (de) | Verfahren zur herstellung von (1r,4s)-2-azabicyclo 2.2.1 hept-5-en-3-on-derivaten | |
| ATE194980T1 (de) | Verfahren zur herstellung von alkylimidazolidinon(meth)acrylates | |
| DE59501585D1 (de) | Verfahren zur Herstellung von Zwischenprodukten für die Synthese von Glucose-6-Phosphatase-Inhibitoren sowie neue Zwischenprodukte | |
| DE69103528D1 (de) | Verfahren zur Herstellung von 7-Alpha-Alkoxycephemderivaten. | |
| ATE188694T1 (de) | Verfahren zur herstellung von benzopyranderivaten | |
| ATE122671T1 (de) | Verfahren zur herstellung von 1,3-dioxan-4,6- dionderivaten. | |
| ATE287877T1 (de) | Verfahren zur herstellung von 5-alkoxy-oxazolen sowie von pyridoxinen | |
| ATE120740T1 (de) | Verfahren und zwischenprodukte zur herstellung von optisch aktiven chromanderivaten. | |
| ATE127774T1 (de) | Verfahren zur herstellung von bicyclo(3.2.0)hept- 2-en-7-onen. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |