ATE251674T1 - Verfahren, reagenz und salz zum nachweis und amplifikation von nukleinsäuresequenzen - Google Patents

Verfahren, reagenz und salz zum nachweis und amplifikation von nukleinsäuresequenzen

Info

Publication number
ATE251674T1
ATE251674T1 AT93918645T AT93918645T ATE251674T1 AT E251674 T1 ATE251674 T1 AT E251674T1 AT 93918645 T AT93918645 T AT 93918645T AT 93918645 T AT93918645 T AT 93918645T AT E251674 T1 ATE251674 T1 AT E251674T1
Authority
AT
Austria
Prior art keywords
detection
nucleic acid
amplification
reagent
salt
Prior art date
Application number
AT93918645T
Other languages
English (en)
Inventor
Craig W Adams
David W Daniels
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26748925&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE251674(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Application granted granted Critical
Publication of ATE251674T1 publication Critical patent/ATE251674T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6862—Ligase chain reaction [LCR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Detergent Compositions (AREA)
AT93918645T 1992-08-04 1993-08-04 Verfahren, reagenz und salz zum nachweis und amplifikation von nukleinsäuresequenzen ATE251674T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92505992A 1992-08-04 1992-08-04
US08/068,393 US6180338B1 (en) 1992-08-04 1993-05-27 Method, reagent and kit for the detection and amplification of nucleic acid sequences
PCT/US1993/007342 WO1994003630A2 (en) 1992-08-04 1993-08-04 Method, reagent and kit for the detection and amplification of nucleic acid sequences

Publications (1)

Publication Number Publication Date
ATE251674T1 true ATE251674T1 (de) 2003-10-15

Family

ID=26748925

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93918645T ATE251674T1 (de) 1992-08-04 1993-08-04 Verfahren, reagenz und salz zum nachweis und amplifikation von nukleinsäuresequenzen

Country Status (11)

Country Link
US (1) US6180338B1 (de)
EP (1) EP0658212B1 (de)
JP (1) JPH07509371A (de)
AT (1) ATE251674T1 (de)
AU (1) AU676197B2 (de)
CA (1) CA2141537A1 (de)
DE (1) DE69333242T2 (de)
FI (1) FI950487L (de)
PL (1) PL307341A1 (de)
RU (1) RU95106503A (de)
WO (1) WO1994003630A2 (de)

Families Citing this family (39)

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JPH08508636A (ja) * 1993-01-27 1996-09-17 オンコール インコーポレーテッド 核酸配列の増幅
US6096880A (en) * 1993-04-15 2000-08-01 University Of Rochester Circular DNA vectors for synthesis of RNA and DNA
US7135312B2 (en) 1993-04-15 2006-11-14 University Of Rochester Circular DNA vectors for synthesis of RNA and DNA
US6077668A (en) * 1993-04-15 2000-06-20 University Of Rochester Highly sensitive multimeric nucleic acid probes
WO1995021270A2 (en) * 1994-02-04 1995-08-10 Beckman Instruments, Inc. Method, reagent and kit for the detection and amplification of nucleic acid sequences
DE69427876T2 (de) * 1994-05-23 2002-04-11 Biotronics Corp., Lowell Methode zur detektion einer gezielten nukleinsäure
US5750341A (en) * 1995-04-17 1998-05-12 Lynx Therapeutics, Inc. DNA sequencing by parallel oligonucleotide extensions
EP0832280A2 (de) * 1995-06-07 1998-04-01 Abbott Laboratories Maskierungsmethode von proben zur reduktion des hintergrundes in der amplifikationsreaktion
ATE324464T1 (de) * 1995-12-05 2006-05-15 Jorn Erland Koch Eine in kaskaden verlaufende vervielfältigungsreaktion von nukleinsäuren
US6852487B1 (en) * 1996-02-09 2005-02-08 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
US20020150921A1 (en) * 1996-02-09 2002-10-17 Francis Barany Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
GB9609213D0 (en) * 1996-05-02 1996-07-03 Tepnel Medical Ltd Amplification of nucleic acids
EP1736554B1 (de) 1996-05-29 2013-10-09 Cornell Research Foundation, Inc. Bestimmung von Unterschieden in der Nukleinsäuresequenz mittels einer Kombination von Ligasebestimmung und Polymerasekettenreaktion
GB9626074D0 (en) * 1996-12-16 1997-02-05 Cytocell Ltd Nucleic acids amplification assay
FR2779154B1 (fr) * 1998-05-27 2002-07-12 Bio Merieux Procede d'amplification d'au moins une sequence nucleotidique particuliere et amorces de mise en oeuvre
FR2786789B1 (fr) * 1998-12-08 2001-12-28 Proteus Methode de detection in vitro d'une sequence d'acide nucleique cible dans un echantillon d'acide nucleique
US6911307B1 (en) 1998-12-08 2005-06-28 Proteus S.A. Method of detection in vitro of a target substance in a sample comprising the labelling of said substance with a reporter gene and with the sequences necessary for the expression of said reporter gene in vitro
US6506594B1 (en) * 1999-03-19 2003-01-14 Cornell Res Foundation Inc Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
US6368834B1 (en) * 1999-04-06 2002-04-09 Genome Technologies, Llc PCR genome walking with synthetic primer
JP2001249996A (ja) * 1999-12-28 2001-09-14 Sony Corp ホームドクターシステム、血液収納用カプセルおよび注射装置
US20040146918A1 (en) * 2000-02-18 2004-07-29 Weiner Michael L. Hybrid nucleic acid assembly
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
US6942972B2 (en) 2001-10-24 2005-09-13 Beckman Coulter, Inc. Efficient synthesis of protein-oligonucleotide conjugates
BRPI0408967B8 (pt) 2003-03-31 2021-07-27 Hoffmann La Roche kit e métodos para detecção de um ácido nucléico de vários membros do sorogrupo do vírus da encefalite japonesa em uma amostra biológica sob condições de hibridização rigorosas
US7449292B2 (en) 2003-09-12 2008-11-11 University Of Cincinnati Methods for predicting relative efficacy of a beta blocker therapy based on a B1-adrenergic receptor polymorphism
EP1802775B1 (de) 2004-09-14 2010-05-26 The Regents of the University of Colorado Auf genetischem targeting basierendes verfahren zur behandlung mit bucindolol
WO2006081426A2 (en) * 2005-01-28 2006-08-03 Applera Corporation Compositions and methods for terminating a sequencing reaction at a specific location in a target dna template
EP1871896B1 (de) 2005-04-12 2015-06-03 Olink AB Zirkulare Sonden und deren Verwendung zur Identifizierung von Biomolekülen
EP1871897B1 (de) 2005-04-12 2010-09-29 Olink AB Verfahren zur herstellung von oligonukleotiden
US7501254B2 (en) * 2006-07-20 2009-03-10 Ghc Technologies, Inc. Methods and compositions for amplification and capture of nucleic acid sequences
GB2466442A (en) * 2008-12-18 2010-06-23 Dublin Inst Of Technology A system to analyze a sample on a slide using Raman spectroscopy on an identified area of interest
EP2705162B1 (de) 2011-05-04 2018-07-11 Biocept, Inc. Verfahren zur erkennung von nukleinsäuresequenzvarianten
US20150011396A1 (en) 2012-07-09 2015-01-08 Benjamin G. Schroeder Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing
US9822408B2 (en) 2013-03-15 2017-11-21 Nugen Technologies, Inc. Sequential sequencing
CA2929596C (en) 2013-11-13 2022-07-05 Nugen Technologies, Inc. Compositions and methods for identification of a duplicate sequencing read
US12492430B2 (en) 2017-04-11 2025-12-09 Tecan Genomics, Inc. Library quantitation and qualification
US11099202B2 (en) 2017-10-20 2021-08-24 Tecan Genomics, Inc. Reagent delivery system
EP3851542A1 (de) 2020-01-20 2021-07-21 Tecan Genomics, Inc. Verarmung von reichlich uninformativen sequenzen
US12059674B2 (en) 2020-02-03 2024-08-13 Tecan Genomics, Inc. Reagent storage system

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883750A (en) 1984-12-13 1989-11-28 Applied Biosystems, Inc. Detection of specific sequences in nucleic acids
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
CA1338457C (en) 1986-08-22 1996-07-16 Henry A. Erlich Purified thermostable enzyme
IL86164A0 (en) 1987-04-28 1988-11-15 Tamir Biotechnology Ltd Improved dna probes
US5093245A (en) 1988-01-26 1992-03-03 Applied Biosystems Labeling by simultaneous ligation and restriction
IE61148B1 (en) 1988-03-10 1994-10-05 Ici Plc Method of detecting nucleotide sequences
US4988617A (en) 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
WO1989009835A1 (en) 1988-04-08 1989-10-19 The Salk Institute For Biological Studies Ligase-based amplification method
EP0379559B1 (de) 1988-06-24 1996-10-23 Amgen Inc. Verfahren und mittel zum nachweis von nukleinsäuresequenzen
JP2955759B2 (ja) * 1988-07-20 1999-10-04 セゲブ・ダイアグノスティックス・インコーポレイテッド 核酸配列を増幅及び検出する方法
US5185243A (en) 1988-08-25 1993-02-09 Syntex (U.S.A.) Inc. Method for detection of specific nucleic acid sequences
GB2225112A (en) 1988-11-22 1990-05-23 Ici Plc Hybridisation probes
AU627809B2 (en) 1988-12-16 1992-09-03 Abbott Laboratories Isolating thermostable enzymes from engineered mesophiles
US4994370A (en) 1989-01-03 1991-02-19 The United States Of America As Represented By The Department Of Health And Human Services DNA amplification technique
US5427930A (en) * 1990-01-26 1995-06-27 Abbott Laboratories Amplification of target nucleic acids using gap filling ligase chain reaction
DE69118930T2 (de) 1990-01-26 1997-01-09 Abbott Lab Verbessertes Verfahren zur Amplifikation von Nuklein säurezielsequenz, einsetzbar für die Polymerase und Ligasekettenreaktion
CA2039517C (en) 1990-04-03 2006-11-07 David Segev Dna probe signal amplification
HU218095B (hu) 1990-05-01 2000-05-28 Amgen Inc. Eljárás átvitt szennyeződések csökkentésére, amplifikációs eljárásokban
DE69133629D1 (de) 1990-05-03 2010-04-15 Cornell Res Foundation Inc nssystem zur Bestimmung von genetischen Krankheiten
CA2049879A1 (en) 1990-08-30 1992-03-01 Keith C. Backman Controlled initial target-dependent production of templates for ligase chain reaction
CA2052413C (en) 1990-09-28 2004-07-13 Jeffrey L. Joseph Nucleotides sequences useful as type-specific probes, pcr primers and lcr probes for the amplifications and detection of human papilloma virus, and related kits and methods
WO1995021270A2 (en) * 1994-02-04 1995-08-10 Beckman Instruments, Inc. Method, reagent and kit for the detection and amplification of nucleic acid sequences

Also Published As

Publication number Publication date
PL307341A1 (en) 1995-05-15
FI950487A7 (fi) 1995-03-10
US6180338B1 (en) 2001-01-30
DE69333242T2 (de) 2004-08-26
EP0658212A1 (de) 1995-06-21
RU95106503A (ru) 1997-05-10
JPH07509371A (ja) 1995-10-19
WO1994003630A2 (en) 1994-02-17
FI950487A0 (fi) 1995-02-03
AU676197B2 (en) 1997-03-06
CA2141537A1 (en) 1994-02-17
WO1994003630A3 (en) 1994-03-31
AU4802793A (en) 1994-03-03
DE69333242D1 (de) 2003-11-13
FI950487L (fi) 1995-03-10
EP0658212B1 (de) 2003-10-08

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