ATE253635T1 - Rekombinante spinnerseide analoge - Google Patents

Rekombinante spinnerseide analoge

Info

Publication number
ATE253635T1
ATE253635T1 AT94920732T AT94920732T ATE253635T1 AT E253635 T1 ATE253635 T1 AT E253635T1 AT 94920732 T AT94920732 T AT 94920732T AT 94920732 T AT94920732 T AT 94920732T AT E253635 T1 ATE253635 T1 AT E253635T1
Authority
AT
Austria
Prior art keywords
spinner
analogue
silk
recombinant
coli
Prior art date
Application number
AT94920732T
Other languages
English (en)
Inventor
Stephen R Fahnestock
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Application granted granted Critical
Publication of ATE253635T1 publication Critical patent/ATE253635T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
    • F02B75/00—Other engines
    • F02B75/02—Engines characterised by their cycles, e.g. six-stroke
    • F02B2075/022—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
    • F02B2075/027—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Insects & Arthropods (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Materials For Medical Uses (AREA)
AT94920732T 1993-06-15 1994-06-15 Rekombinante spinnerseide analoge ATE253635T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7760093A 1993-06-15 1993-06-15
PCT/US1994/006689 WO1994029450A2 (en) 1993-06-15 1994-06-15 Novel, recombinantly produced spider silk analogs

Publications (1)

Publication Number Publication Date
ATE253635T1 true ATE253635T1 (de) 2003-11-15

Family

ID=22139030

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94920732T ATE253635T1 (de) 1993-06-15 1994-06-15 Rekombinante spinnerseide analoge

Country Status (7)

Country Link
US (1) US6268169B1 (de)
EP (2) EP0707645B1 (de)
JP (1) JPH08511426A (de)
AT (1) ATE253635T1 (de)
CA (1) CA2164692C (de)
DE (1) DE69433299T2 (de)
WO (1) WO1994029450A2 (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4303418B2 (ja) * 1997-10-24 2009-07-29 ライフ テクノロジーズ コーポレーション 組換え部位を有する核酸を使用する組換えクローニング
FR2774588B1 (fr) * 1998-02-11 2000-05-05 Oreal Composition cosmetique ou dermatologique contenant au moins une proteine de soie d'arachnides naturelle, recombinante ou un analogue
US20010053931A1 (en) * 1999-11-24 2001-12-20 Salvatore J. Abbruzzese Thin-layered, endovascular silk-covered stent device and method of manufacture thereof
US6608242B1 (en) * 2000-05-25 2003-08-19 E. I. Du Pont De Nemours And Company Production of silk-like proteins in plants
CA2411600A1 (en) * 2000-06-09 2001-12-13 Ipk Institut Fur Pflanzenzengenetik Und Kulturplanzenforschung Synthetic spider silk proteins and the expression thereof in transgenic plants
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
FR2817260A1 (fr) * 2000-11-29 2002-05-31 Centre Nat Rech Scient Peptides ayant des proprietes anti-inflammatoires, leurs utilisations et les compositions les contenant
CN1216072C (zh) * 2001-07-13 2005-08-24 一泰医药研究（深圳）有限公司 序列号5的生物活性肽
ATE414099T1 (de) 2001-07-13 2008-11-15 Cms Peptides Patent Holding Co Biologisch aktive peptide
US7057023B2 (en) * 2002-01-11 2006-06-06 Nexia Biotechnologies Inc. Methods and apparatus for spinning spider silk protein
WO2003069033A1 (en) 2002-02-14 2003-08-21 The University Of British Columbia α-HELICAL PROTEIN BASED MATERIALS AND METHODS FOR MAKING SAME
US20060019348A1 (en) * 2002-05-23 2006-01-26 Tetsuo Asakura Method of mass producing silk protein and gene recombinant silk-like protein with added functionality
US20040117874A1 (en) * 2002-10-15 2004-06-17 Jianjun Yang Methods for accumulating translocated proteins
US20040132978A1 (en) * 2002-11-12 2004-07-08 Fahnestock Stephen R. Method for purifying and recovering silk proteins in soluble form and uses thereof
JP2004206910A (ja) * 2002-12-24 2004-07-22 Sumitomo Wiring Syst Ltd ヒューズコネクタ
US20040225077A1 (en) 2002-12-30 2004-11-11 Angiotech International Ag Drug delivery from rapid gelling polymer composition
CA2511484A1 (en) * 2002-12-30 2004-07-22 Angiotech International Ag Silk-containing stent graft
US7060260B2 (en) * 2003-02-20 2006-06-13 E.I. Du Pont De Nemours And Company Water-soluble silk proteins in compositions for skin care, hair care or hair coloring
GB0319174D0 (en) * 2003-08-15 2003-09-17 Spinox Ltd Apparatus and method for the selective assembly of protein
AU2004289362A1 (en) * 2003-11-10 2005-05-26 Angiotech International Ag Intravascular devices and fibrosis-inducing agents
US8304189B2 (en) 2003-12-01 2012-11-06 Life Technologies Corporation Nucleic acid molecules containing recombination sites and methods of using the same
CN1910196A (zh) * 2004-01-13 2007-02-07 东丽株式会社 含有蜘蛛丝蛋白质的丝线以及产生该丝线的蚕
US20050161058A1 (en) 2004-01-26 2005-07-28 Israel Yerushalmy Spider silk dental floss
TWI353252B (en) 2004-04-28 2011-12-01 Cms Peptides Patent Holding Company Ltd Biologically active peptide vapeehptllteaplnpk der
US20050261479A1 (en) * 2004-04-29 2005-11-24 Christian Hoffmann Method for purifying and recovering silk proteins using magnetic affinity separation
US20060027247A1 (en) * 2004-08-06 2006-02-09 Thomas Studney Transgenic spider silk floss
WO2006076711A2 (en) 2005-01-14 2006-07-20 Trustees Of Tufts College Fibrous protein fusions and use thereof in the formation of advanced organic/inorganic composite materials
NZ591827A (en) 2005-07-26 2012-10-26 Cms Peptides Patent Holding Company Ltd Biologically active peptides comprising PTTKTYFPHF and their uses in the manufacture of a medicament for modulating immune reaction in a radiotherapy-induced immuno-compromised subject
PT1757276E (pt) 2005-08-01 2008-01-02 Univ Muenchen Tech Método para produzir nano- e microcápsulas de proteína de seda de aranha
RU2421463C2 (ru) * 2005-08-29 2011-06-20 АЭмЗильк ГмбХ Способ модификации белка шелка пауков, модифицированный белок шелка пауков, кодирующая его последовательность нуклеиновой кислоты, вектор и клетка-хозяин для его экспрессии
CA2624667C (en) 2005-10-05 2018-01-09 Commonwealth Scientific And Industrial Research Organisation Silk proteins containing coiled coil region
AU2006333611B2 (en) 2005-12-30 2012-04-26 Spiber Technologies Ab Spider silk proteins and methods for producing spider silk proteins
DE102007002222A1 (de) 2007-01-10 2008-07-17 Gustav Pirazzi & Comp. Kg Verwendung von künstlich hergestellter Spinnenseide
CA2675592A1 (en) * 2007-01-18 2008-07-24 Danisco Us, Inc., Genencor Division Modified endoglucanase ii and methods of use
BRPI0701826B1 (pt) 2007-03-16 2021-02-17 Embrapa - Empresa Brasileira De Pesquisa Agropecuária proteínas da teia de aranha nephilengys cruentata, avicularia juruensis e parawixia bistriata isoladas da biodiversidade brasileira
DE102007019622B4 (de) 2007-04-24 2010-07-01 Birgit Riesinger Expandierbarer Wundverband
WO2008155304A1 (de) * 2007-06-20 2008-12-24 Basf Se Synthetische repetitive proteine, deren herstellung und verwendung
WO2009097540A1 (en) 2008-02-01 2009-08-06 Entogenetics, Inc. Methods, compositions, and systems for production of recombinant spider silk polypeptides
CN102812036B (zh) 2009-08-26 2016-08-03 联邦科学工业研究组织 用于生产丝纺丝液的方法
JP5691052B2 (ja) * 2010-09-10 2015-04-01 岡本株式会社 組換え生物及び組換え生物により作られるタンパク質
EP2844360B1 (de) * 2012-05-02 2018-12-19 Spiber Technologies AB Spinnenseidenfusionsproteinstrukturen ohne repetitives fragment zur bindung an ein organisches target
WO2014062134A1 (en) 2012-10-17 2014-04-24 Nanyang Technological University Compounds and methods for the production of suckerin and uses thereof
US20150293076A1 (en) * 2012-10-22 2015-10-15 Bolt Threads, Inc. Cellular Reprogramming for Product Optimization
WO2015042164A2 (en) 2013-09-17 2015-03-26 Refactored Materials, Inc. Methods and compositions for synthesizing improved silk fibers
WO2017115005A1 (en) 2015-12-29 2017-07-06 Teknologian Tutkimuskeskus Vtt Oy Production of fusion proteins in trichoderma
KR20190046993A (ko) 2016-09-14 2019-05-07 볼트 쓰레즈, 인크. 긴 균일한 재조합 단백질 섬유
WO2019060921A1 (en) 2017-09-25 2019-03-28 Bolt Threads, Inc. METHODS OF GENERATING HIGHLY CRYSTALLINE RECOMBINANT SPIDER SILK PROTEIN FIBERS
US11667682B2 (en) 2018-12-13 2023-06-06 Washington University Split intein mediated protein polymerization for microbial production of materials
US20240287443A1 (en) * 2021-06-24 2024-08-29 Reliance Industries Limited Recombinant algae and production of spider silk protein from the recombinant algae
WO2023076924A1 (en) 2021-10-26 2023-05-04 Rensselaer Polytechnic Institute Systems and methods for increased production of recombinant biopolymers via genome engineering and downregulation of basal expression

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0230702A1 (de) 1986-01-22 1987-08-05 PA Consulting Services Limited Herstellung von Seide
JPS6236183A (ja) 1985-06-20 1987-02-17 ザ・サルク・インステイチユ−ト・バイオテクノロジ−／インダストリアル・アソシエイツ・インコ−ポレ−テツド サツカロミセス・セレビシエからのポリペプチドの発現および分泌
JPH01501755A (ja) * 1986-11-04 1989-06-22 シントロ　コーポレイション 合成ｄｎａの構成および大ポリペプチドの合成におけるその使用
US5243038A (en) * 1986-11-04 1993-09-07 Protein Polymer Technologies, Inc. Construction of synthetic DNA and its use in large polypeptide synthesis
AU7691191A (en) * 1990-04-19 1991-11-11 United States Of America, As Represented By The Secretary Of The Army, The Recombinant spider silk proteins through genetic engineering
US5245012A (en) * 1990-04-19 1993-09-14 The United States Of America As Represented By The Secretary Of The Army Method to achieve solubilization of spider silk proteins
EP0452925B1 (de) * 1990-04-20 2000-02-09 The University Of Wyoming Für Spinnenseideprotein kodierende DNS, DNS enthaltender Vektor, transformierte Zelle und Produkte davon
US5171505A (en) 1990-11-28 1992-12-15 E. I. Du Pont De Nemours And Company Process for spinning polypeptide fibers

Also Published As

Publication number Publication date
US6268169B1 (en) 2001-07-31
EP1413585A2 (de) 2004-04-28
DE69433299T2 (de) 2004-09-09
WO1994029450A2 (en) 1994-12-22
CA2164692C (en) 2003-02-04
CA2164692A1 (en) 1994-12-22
JPH08511426A (ja) 1996-12-03
WO1994029450A3 (en) 1995-02-09
EP0707645A1 (de) 1996-04-24
DE69433299D1 (de) 2003-12-11
EP0707645B1 (de) 2003-11-05
EP1413585A3 (de) 2004-08-04

Similar Documents

Publication Publication Date Title
DE69433299D1 (de) Rekombinante spinnerseide analoge
DE69942035D1 (de) Menschliches parathyroidhormon, modifikationen, herstellung und verwendung
EP0212474A3 (de) Morphogenetische Knochenpeptide
DK0792287T3 (da) Peptidanaloger af humant basisk myelinprotein
DK0409472T3 (da) Knoglemorfogenetisk protein
DE69839812D1 (de) Analoge des menschlichen interferon-alpha mit niedriger toxizität
MY123740A (en) Il-13 receptor polypeptide
ATE430801T1 (de) Von wd-40 abstammende peptide und ihre verwendung
DK0643767T3 (da) Osteogene peptider
ATE273997T1 (de) Zyklische hexapeptid somatostatin analoga
GB9606040D0 (en) Active peptide
DE68917837D1 (de) Peptid-Verbindungen.
ATE237634T1 (de) Analogen des keratinozytenwachstumfaktors
ATE182900T1 (de) Mutierte form von dem beta-amyloidprecursor proteine gen
ATE161884T1 (de) Rekombinantes-21-kd-kakaoprotein und präkursor
ATE124955T1 (de) Substrat-peptide.
KR880701073A (ko) 제조합 dna 기법에 의해 생성된 민악티빈
DE59109235D1 (de) Peptide des HIV-gag Proteins, ihre Herstellung und Verwendung
ATE251640T1 (de) Neues chondrozytprotein
DE69623803D1 (de) Verwendung von KASEINFRAGMENTEn als WACHSTUMERFÖRDERer
EP1295943A4 (de) Polypeptide mit aktivität der stimulierung von neutrophilen
WO1999060117A3 (fr) Polypeptide prax-1

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties