ATE253635T1 - Rekombinante spinnerseide analoge - Google Patents

Rekombinante spinnerseide analoge

Info

Publication number
ATE253635T1
ATE253635T1 AT94920732T AT94920732T ATE253635T1 AT E253635 T1 ATE253635 T1 AT E253635T1 AT 94920732 T AT94920732 T AT 94920732T AT 94920732 T AT94920732 T AT 94920732T AT E253635 T1 ATE253635 T1 AT E253635T1
Authority
AT
Austria
Prior art keywords
spinner
analogue
silk
recombinant
coli
Prior art date
Application number
AT94920732T
Other languages
English (en)
Inventor
Stephen R Fahnestock
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Application granted granted Critical
Publication of ATE253635T1 publication Critical patent/ATE253635T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
    • F02B75/00—Other engines
    • F02B75/02—Engines characterised by their cycles, e.g. six-stroke
    • F02B2075/022—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
    • F02B2075/027—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Insects & Arthropods (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Materials For Medical Uses (AREA)
AT94920732T 1993-06-15 1994-06-15 Rekombinante spinnerseide analoge ATE253635T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7760093A 1993-06-15 1993-06-15
PCT/US1994/006689 WO1994029450A2 (en) 1993-06-15 1994-06-15 Novel, recombinantly produced spider silk analogs

Publications (1)

Publication Number Publication Date
ATE253635T1 true ATE253635T1 (de) 2003-11-15

Family

ID=22139030

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94920732T ATE253635T1 (de) 1993-06-15 1994-06-15 Rekombinante spinnerseide analoge

Country Status (7)

Country Link
US (1) US6268169B1 (de)
EP (2) EP0707645B1 (de)
JP (1) JPH08511426A (de)
AT (1) ATE253635T1 (de)
CA (1) CA2164692C (de)
DE (1) DE69433299T2 (de)
WO (1) WO1994029450A2 (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU752704B2 (en) * 1997-10-24 2002-09-26 Invitrogen Corporation Recombinational cloning using nucleic acids having recombination sites
FR2774588B1 (fr) 1998-02-11 2000-05-05 Oreal Composition cosmetique ou dermatologique contenant au moins une proteine de soie d'arachnides naturelle, recombinante ou un analogue
US20010053931A1 (en) * 1999-11-24 2001-12-20 Salvatore J. Abbruzzese Thin-layered, endovascular silk-covered stent device and method of manufacture thereof
US6608242B1 (en) 2000-05-25 2003-08-19 E. I. Du Pont De Nemours And Company Production of silk-like proteins in plants
EP1287139B1 (de) * 2000-06-09 2010-08-25 Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung (IPK) Synthetische spinnenseidenproteine und deren expression in transgenen pflanzen
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
FR2817260A1 (fr) * 2000-11-29 2002-05-31 Centre Nat Rech Scient Peptides ayant des proprietes anti-inflammatoires, leurs utilisations et les compositions les contenant
CN100412087C (zh) * 2001-07-13 2008-08-20 泰哲医药研究（深圳）有限公司 序列号2的生物活性肽
SG185137A1 (en) 2001-07-13 2012-11-29 Cms Peptides Patent Holding Company Ltd Biologically active peptides
US7057023B2 (en) * 2002-01-11 2006-06-06 Nexia Biotechnologies Inc. Methods and apparatus for spinning spider silk protein
CA2473772A1 (en) 2002-02-14 2003-08-21 The University Of British Columbia .alpha.-helical protein based materials and methods for making same
US20060019348A1 (en) * 2002-05-23 2006-01-26 Tetsuo Asakura Method of mass producing silk protein and gene recombinant silk-like protein with added functionality
US20040117874A1 (en) * 2002-10-15 2004-06-17 Jianjun Yang Methods for accumulating translocated proteins
US20040132978A1 (en) * 2002-11-12 2004-07-08 Fahnestock Stephen R. Method for purifying and recovering silk proteins in soluble form and uses thereof
JP2004206910A (ja) * 2002-12-24 2004-07-22 Sumitomo Wiring Syst Ltd ヒューズコネクタ
ATE457716T1 (de) 2002-12-30 2010-03-15 Angiotech Int Ag Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung
US20040199241A1 (en) * 2002-12-30 2004-10-07 Angiotech International Ag Silk stent grafts
US7060260B2 (en) * 2003-02-20 2006-06-13 E.I. Du Pont De Nemours And Company Water-soluble silk proteins in compositions for skin care, hair care or hair coloring
GB0319174D0 (en) * 2003-08-15 2003-09-17 Spinox Ltd Apparatus and method for the selective assembly of protein
AU2004289362A1 (en) * 2003-11-10 2005-05-26 Angiotech International Ag Intravascular devices and fibrosis-inducing agents
ATE469984T1 (de) 2003-12-01 2010-06-15 Life Technologies Corp Rekombinationsstellen enthaltende nukleinsäuremoleküle und verfahren zur verwendung davon
EP1712561A4 (de) * 2004-01-13 2008-09-03 Toray Industries Seidenfaden mit spinnenfadenprotein und den seidenfaden herstellende seidenraupe
US20050161058A1 (en) 2004-01-26 2005-07-28 Israel Yerushalmy Spider silk dental floss
TWI353252B (en) 2004-04-28 2011-12-01 Cms Peptides Patent Holding Company Ltd Biologically active peptide vapeehptllteaplnpk der
US20050261479A1 (en) * 2004-04-29 2005-11-24 Christian Hoffmann Method for purifying and recovering silk proteins using magnetic affinity separation
US20060027247A1 (en) * 2004-08-06 2006-02-09 Thomas Studney Transgenic spider silk floss
WO2006076711A2 (en) * 2005-01-14 2006-07-20 Trustees Of Tufts College Fibrous protein fusions and use thereof in the formation of advanced organic/inorganic composite materials
CA2616525C (en) 2005-07-26 2014-06-17 Cms Peptides Patent Holding Company Limited Novel biologically active peptides and their new uses
PL1757276T3 (pl) 2005-08-01 2008-02-29 Amsilk Gmbh Sposób otrzymywania nano-i mikrokapsułek z białka pajęczego jedwabiu
CA2619917C (en) * 2005-08-29 2013-04-23 Technische Universitaet Muenchen Modified spider silk proteins
NZ567202A (en) 2005-10-05 2012-02-24 Commw Scient Ind Res Org Silk proteins from Hyhemonptera species containing heptad repeats that form coiled coil tertiary structures
AU2006333611B2 (en) 2005-12-30 2012-04-26 Spiber Technologies Ab Spider silk proteins and methods for producing spider silk proteins
DE102007002222A1 (de) 2007-01-10 2008-07-17 Gustav Pirazzi & Comp. Kg Verwendung von künstlich hergestellter Spinnenseide
EP2121911A2 (de) * 2007-01-18 2009-11-25 Danisco US, INC., Genencor Division Modifizierte endoglucanase ii und verwendungsverfahren
BRPI0701826B1 (pt) 2007-03-16 2021-02-17 Embrapa - Empresa Brasileira De Pesquisa Agropecuária proteínas da teia de aranha nephilengys cruentata, avicularia juruensis e parawixia bistriata isoladas da biodiversidade brasileira
DE102007019622B4 (de) 2007-04-24 2010-07-01 Birgit Riesinger Expandierbarer Wundverband
CN101855239B (zh) * 2007-06-20 2013-11-06 巴斯夫欧洲公司 合成的重复蛋白及其生产和用途
US9131671B2 (en) * 2008-02-01 2015-09-15 Entogenetics, Inc. Methods, compositions and systems for production of recombinant spider silk polypeptides
US8674077B2 (en) 2009-08-26 2014-03-18 Commonwealth Scientific And Industrial Research Organisation Processes for producing silk dope
JP5691052B2 (ja) 2010-09-10 2015-04-01 岡本株式会社 組換え生物及び組換え生物により作られるタンパク質
JP6412866B2 (ja) * 2012-05-02 2018-10-24 スパイバー テクノロジーズ アーベーＳｐｉｂｅｒ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ａｂ 有機ターゲットに結合するための反復断片を持たないクモ糸融合タンパク質の構造
SG10201703051WA (en) 2012-10-17 2017-06-29 Univ Nanyang Tech Compounds and methods for the production of suckerin and uses thereof
US20150293076A1 (en) * 2012-10-22 2015-10-15 Bolt Threads, Inc. Cellular Reprogramming for Product Optimization
ES2887366T3 (es) 2013-09-17 2021-12-22 Bolt Threads Inc Métodos y composiciones para sintetizar fibras de seda mejoradas
WO2017115005A1 (en) 2015-12-29 2017-07-06 Teknologian Tutkimuskeskus Vtt Oy Production of fusion proteins in trichoderma
CA3035839A1 (en) 2016-09-14 2018-03-22 Bolt Threads, Inc. Long uniform recombinant protein fibers
WO2019060921A1 (en) 2017-09-25 2019-03-28 Bolt Threads, Inc. METHODS OF GENERATING HIGHLY CRYSTALLINE RECOMBINANT SPIDER SILK PROTEIN FIBERS
US11667682B2 (en) 2018-12-13 2023-06-06 Washington University Split intein mediated protein polymerization for microbial production of materials
WO2022269557A1 (en) * 2021-06-24 2022-12-29 Reliance Industries Limited Recombinant algae and production of spider silk protein from the recombinant algae
WO2023076924A1 (en) 2021-10-26 2023-05-04 Rensselaer Polytechnic Institute Systems and methods for increased production of recombinant biopolymers via genome engineering and downregulation of basal expression

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0230702A1 (de) * 1986-01-22 1987-08-05 PA Consulting Services Limited Herstellung von Seide
AU5912586A (en) 1985-06-20 1986-12-24 Salk Institute Biotechnology/Industrial Associates, Inc., The Alpha-factor leader peptide-facilitated secretion from transformed s cerevisiae
US5243038A (en) * 1986-11-04 1993-09-07 Protein Polymer Technologies, Inc. Construction of synthetic DNA and its use in large polypeptide synthesis
AU612340B2 (en) * 1986-11-04 1991-07-11 Protein Polymers Technologies, Inc. Construction of synthetic dna and its use in large polypeptide synthesis
US5245012A (en) * 1990-04-19 1993-09-14 The United States Of America As Represented By The Secretary Of The Army Method to achieve solubilization of spider silk proteins
AU7691191A (en) * 1990-04-19 1991-11-11 United States Of America, As Represented By The Secretary Of The Army, The Recombinant spider silk proteins through genetic engineering
DE69131969T2 (de) * 1990-04-20 2000-06-15 The University Of Wyoming, Laramie Für Spinnenseideprotein kodierende DNS, DNS enthaltender Vektor, transformierte Zelle und Produkte davon
US5171505A (en) 1990-11-28 1992-12-15 E. I. Du Pont De Nemours And Company Process for spinning polypeptide fibers

Also Published As

Publication number Publication date
DE69433299T2 (de) 2004-09-09
JPH08511426A (ja) 1996-12-03
WO1994029450A3 (en) 1995-02-09
WO1994029450A2 (en) 1994-12-22
EP1413585A2 (de) 2004-04-28
CA2164692A1 (en) 1994-12-22
DE69433299D1 (de) 2003-12-11
US6268169B1 (en) 2001-07-31
CA2164692C (en) 2003-02-04
EP0707645B1 (de) 2003-11-05
EP1413585A3 (de) 2004-08-04
EP0707645A1 (de) 1996-04-24

Similar Documents

Publication Publication Date Title
ATE253635T1 (de) Rekombinante spinnerseide analoge
DE69942035D1 (de) Menschliches parathyroidhormon, modifikationen, herstellung und verwendung
EP0212474A3 (de) Morphogenetische Knochenpeptide
DK0409472T3 (da) Knoglemorfogenetisk protein
ATE266043T1 (de) Peptidanaloge des menschlichen basischen myelinproteins
ATE402957T1 (de) Analoge des menschlichen interferon-alpha mit niedriger toxizität
ATE430801T1 (de) Von wd-40 abstammende peptide und ihre verwendung
MY123740A (en) Il-13 receptor polypeptide
EP0378641A4 (en) Novel antimicrobial peptide, compositions containing same and uses thereof
DE59007517D1 (de) Neue proteine mit tnf-hemmender wirkung und ihre herstellung.
ATE273997T1 (de) Zyklische hexapeptid somatostatin analoga
GB9606040D0 (en) Active peptide
CA2006087A1 (en) Polypeptides isolated from the venom of the spider hololena curta
ATE110742T1 (de) Peptid-verbindungen.
ATE182900T1 (de) Mutierte form von dem beta-amyloidprecursor proteine gen
ATE161884T1 (de) Rekombinantes-21-kd-kakaoprotein und präkursor
ATE124955T1 (de) Substrat-peptide.
KR880701073A (ko) 제조합 dna 기법에 의해 생성된 민악티빈
DE59108261D1 (de) Peptide des HIV-gag Proteins, ihre Herstellung und Verwendung
ATE251640T1 (de) Neues chondrozytprotein
DE69623803D1 (de) Verwendung von KASEINFRAGMENTEn als WACHSTUMERFÖRDERer
ATE241698T1 (de) Hst-2 mutein, dafür kodierende dns und herstellung
EP1295943A4 (de) Polypeptide mit aktivität der stimulierung von neutrophilen
WO1999060117A3 (fr) Polypeptide prax-1

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties