ATE254636T1 - Biomedizinisches polyurethan, seine herstellung und verwendung - Google Patents

Biomedizinisches polyurethan, seine herstellung und verwendung

Info

Publication number
ATE254636T1
ATE254636T1 AT99939800T AT99939800T ATE254636T1 AT E254636 T1 ATE254636 T1 AT E254636T1 AT 99939800 T AT99939800 T AT 99939800T AT 99939800 T AT99939800 T AT 99939800T AT E254636 T1 ATE254636 T1 AT E254636T1
Authority
AT
Austria
Prior art keywords
production
biomedical polyurethane
biomedical
polyurethane
diol
Prior art date
Application number
AT99939800T
Other languages
English (en)
Inventor
Coenraad Jan Spaans
Groot Jacqueline Hermina De
Folkert Gerhardus Dekens
Albert Johan Pennings
Original Assignee
Polyganics Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polyganics Bv filed Critical Polyganics Bv
Application granted granted Critical
Publication of ATE254636T1 publication Critical patent/ATE254636T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72—Polyisocyanates or polyisothiocyanates
    • C08G18/80—Masked polyisocyanates
    • C08G18/8003—Masked polyisocyanates masked with compounds having at least two groups containing active hydrogen
    • C08G18/8006—Masked polyisocyanates masked with compounds having at least two groups containing active hydrogen with compounds of C08G18/32
    • C08G18/8009—Masked polyisocyanates masked with compounds having at least two groups containing active hydrogen with compounds of C08G18/32 with compounds of C08G18/3203
    • C08G18/8012—Masked polyisocyanates masked with compounds having at least two groups containing active hydrogen with compounds of C08G18/32 with compounds of C08G18/3203 with diols
    • C08G18/8016—Masked aliphatic or cycloaliphatic polyisocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/30—Low-molecular-weight compounds
    • C08G18/32—Polyhydroxy compounds; Polyamines; Hydroxyamines
    • C08G18/3203—Polyhydroxy compounds
    • C08G18/3206—Polyhydroxy compounds aliphatic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/42—Polycondensates having carboxylic or carbonic ester groups in the main chain
    • C08G18/4266—Polycondensates having carboxylic or carbonic ester groups in the main chain prepared from hydroxycarboxylic acids and/or lactones
    • C08G18/4269—Lactones
    • C08G18/4277—Caprolactone and/or substituted caprolactone
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/42—Polycondensates having carboxylic or carbonic ester groups in the main chain
    • C08G18/4266—Polycondensates having carboxylic or carbonic ester groups in the main chain prepared from hydroxycarboxylic acids and/or lactones
    • C08G18/428—Lactides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72—Polyisocyanates or polyisothiocyanates
    • C08G18/73—Polyisocyanates or polyisothiocyanates acyclic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2230/00—Compositions for preparing biodegradable polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Polyurethanes Or Polyureas (AREA)
AT99939800T 1998-06-05 1999-06-04 Biomedizinisches polyurethan, seine herstellung und verwendung ATE254636T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98201868 1998-06-05
PCT/NL1999/000352 WO1999064491A1 (en) 1998-06-05 1999-06-04 Biomedical polyurethane, its preparation and use

Publications (1)

Publication Number Publication Date
ATE254636T1 true ATE254636T1 (de) 2003-12-15

Family

ID=8233784

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99939800T ATE254636T1 (de) 1998-06-05 1999-06-04 Biomedizinisches polyurethan, seine herstellung und verwendung

Country Status (15)

Country Link
US (1) US6784273B1 (de)
EP (2) EP1093483B1 (de)
JP (1) JP4335448B2 (de)
AT (1) ATE254636T1 (de)
AU (1) AU756740B2 (de)
BR (1) BR9910968B1 (de)
CA (1) CA2334110C (de)
DE (1) DE69912956T2 (de)
ES (1) ES2212602T3 (de)
ID (1) ID28196A (de)
IL (2) IL140049A0 (de)
NO (1) NO332315B1 (de)
NZ (1) NZ508907A (de)
WO (1) WO1999064491A1 (de)
ZA (1) ZA200007439B (de)

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US7803395B2 (en) 2003-05-15 2010-09-28 Biomerix Corporation Reticulated elastomeric matrices, their manufacture and use in implantable devices
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US20060135725A1 (en) * 2004-12-21 2006-06-22 Scimed Life Systems, Inc. New balloon materials
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EP2131919A4 (de) * 2007-04-02 2010-10-20 Georgia Tech Res Inst Implantierbre vorrichtung zur kommunikation mit biologischem gewebe
US8182647B2 (en) 2007-07-23 2012-05-22 Cohera Medical, Inc. Hydrophilic biodegradable adhesives
US20090035350A1 (en) * 2007-08-03 2009-02-05 John Stankus Polymers for implantable devices exhibiting shape-memory effects
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US20090123519A1 (en) * 2007-11-12 2009-05-14 Surmodics, Inc. Swellable hydrogel matrix and methods
US20090226531A1 (en) * 2008-03-07 2009-09-10 Allergan, Inc. Methods and composition for intraocular delivery of therapeutic sirna
US9259515B2 (en) * 2008-04-10 2016-02-16 Abbott Cardiovascular Systems Inc. Implantable medical devices fabricated from polyurethanes with grafted radiopaque groups
WO2009141732A2 (en) * 2008-05-19 2009-11-26 Orteq B.V. Polyurethane foam for use in medical implants
US9050176B2 (en) 2009-04-03 2015-06-09 Biomerix Corporation At least partially resorbable reticulated elastomeric matrix elements and methods of making same
EP2413838A4 (de) * 2009-04-03 2012-09-19 Biomerix Corp Zumindest teilweise resorbierbare retikulierte elastomermatrixpartikel und herstellungsverfahren
GB2475778B (en) * 2009-05-20 2013-03-13 Arsenal Medical Inc Medical implant
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NL2002931C2 (en) 2009-05-27 2010-11-30 Polyganics Bv HEMOSTATIC FOAMS.
GB201110601D0 (en) * 2011-06-23 2011-08-03 Controlled Therapeutics Scotland Ltd Improved bioresorbable
US8956682B2 (en) 2012-04-02 2015-02-17 Surmodics, Inc. Hydrophilic polymeric coatings for medical articles with visualization moiety
US20160032239A1 (en) * 2013-03-12 2016-02-04 Northeastern University Deterministic Manufacturing Process For Creating 3D Living Tissues Based on 2D Directed Assembly And Origami Techniques
EP2842583A1 (de) 2013-08-29 2015-03-04 Ella-CS, s.r.o. Biologisch abbaubare und biologisch erodierbare Polyurethane, Verfahren zu ihrer Herstellung und Verwendung
WO2015087741A1 (ja) * 2013-12-09 2015-06-18 株式会社ダイセル ラクトン重合体の製造方法
KR20170125061A (ko) 2015-02-27 2017-11-13 폴리가닉스 아이피 비.브이. 약물 용출 발포체 및 그 제조
NL2016527B1 (en) * 2016-03-31 2017-11-02 Polyganics Ip B V Tissue-adhesive biomedical materials.
NL2016526B1 (en) 2016-03-31 2017-11-02 Polyganics Ip B V Improved biomedical polyurethanes
NL2016524B1 (en) 2016-03-31 2017-10-17 Polyganics Ip B V Tissue-adhesive material
WO2019035357A1 (ja) * 2017-08-17 2019-02-21 東レ株式会社 ポリエステルコポリマーおよびその製造方法
NL2019652B1 (en) * 2017-09-29 2019-04-08 Polyganics Ip B V Tissue-adhesive sealant device
WO2019079622A1 (en) * 2017-10-18 2019-04-25 Bvw Holding Ag DEVICE WITH ABSORPTION PROFILE INVOLVING MICROSTRUCTURES
AU2018389853B2 (en) 2017-12-20 2024-10-31 Stryker European Operations Holdings Llc Biomedical foam
EP3897397B1 (de) 2018-12-20 2023-09-13 Stryker European Operations Limited Verschlusssysteme für schädelbasis
NL2022710B1 (en) 2019-03-11 2020-09-18 Polyganics Ip B V Tissue-adhesive hydrogels
CN113677299B (zh) 2019-04-16 2025-08-29 史赛克欧洲运营有限公司 窦支架和在患者的窦内部署支架的系统和方法
NL2023358B1 (en) 2019-06-21 2021-02-01 Polyganics Ip B V Dopamine-functionalized polymers
CN112220968B (zh) * 2020-12-09 2021-03-26 中国科学院化学研究所 一种长期替代型组织工程半月板支架的光固化3d打印制备方法
IT202300012945A1 (it) * 2023-06-22 2024-12-22 G P S Tech S R L Uso di specifici polioli poliesteri come fase soft per poliuretani facilmente degradabili e poliuretani degradabili così ottenuti
FR3162221A1 (fr) * 2024-05-16 2025-11-21 Arthrocart Biotech Solide poreux biocompatible et biorésorbable pour la réalisation d’implants chirurgicaux

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Also Published As

Publication number Publication date
NO20006180L (no) 2001-01-22
NO332315B1 (no) 2012-08-27
DE69912956D1 (de) 2003-12-24
ID28196A (id) 2001-05-10
EP1093483B1 (de) 2003-11-19
BR9910968B1 (pt) 2009-05-05
AU756740B2 (en) 2003-01-23
NZ508907A (en) 2004-12-24
NO20006180D0 (no) 2000-12-05
BR9910968A (pt) 2001-02-13
EP1308473A1 (de) 2003-05-07
US6784273B1 (en) 2004-08-31
AU4293299A (en) 1999-12-30
JP4335448B2 (ja) 2009-09-30
IL140049A (en) 2008-03-20
DE69912956T2 (de) 2004-11-11
ES2212602T3 (es) 2004-07-16
JP2002517577A (ja) 2002-06-18
WO1999064491A1 (en) 1999-12-16
CA2334110C (en) 2011-09-20
ZA200007439B (en) 2001-08-08
EP1093483A1 (de) 2001-04-25
CA2334110A1 (en) 1999-12-16
IL140049A0 (en) 2002-02-10

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