ATE256185T1 - T-zell-membranprotein (tirc7), davon abgeleitete peptide und antikörper und ihre verwendungen - Google Patents

T-zell-membranprotein (tirc7), davon abgeleitete peptide und antikörper und ihre verwendungen

Info

Publication number
ATE256185T1
ATE256185T1 AT98945293T AT98945293T ATE256185T1 AT E256185 T1 ATE256185 T1 AT E256185T1 AT 98945293 T AT98945293 T AT 98945293T AT 98945293 T AT98945293 T AT 98945293T AT E256185 T1 ATE256185 T1 AT E256185T1
Authority
AT
Austria
Prior art keywords
cell
peptides
tirc7
membrane protein
cell membrane
Prior art date
Application number
AT98945293T
Other languages
English (en)
Inventor
Nalan Utku
Steven R Gullans
Edgar L Milford
Original Assignee
Brigham & Womens Hospital
Nalan Utku
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19738710A external-priority patent/DE19738710A1/de
Application filed by Brigham & Womens Hospital, Nalan Utku filed Critical Brigham & Womens Hospital
Application granted granted Critical
Publication of ATE256185T1 publication Critical patent/ATE256185T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT98945293T 1997-08-29 1998-08-28 T-zell-membranprotein (tirc7), davon abgeleitete peptide und antikörper und ihre verwendungen ATE256185T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19738710A DE19738710A1 (de) 1997-08-29 1997-08-29 Verwendung von TIRC7 zur Herstellung von Mitteln zur Inhibition der Immunantwort
DE29802653 1998-02-12
PCT/EP1998/005462 WO1999011782A1 (en) 1997-08-29 1998-08-28 T-cell membrane protein (tirc7), peptides and antibodies derived therefrom and uses thereof

Publications (1)

Publication Number Publication Date
ATE256185T1 true ATE256185T1 (de) 2003-12-15

Family

ID=26039678

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98945293T ATE256185T1 (de) 1997-08-29 1998-08-28 T-zell-membranprotein (tirc7), davon abgeleitete peptide und antikörper und ihre verwendungen

Country Status (10)

Country Link
EP (2) EP0996726B1 (de)
JP (1) JP4459435B2 (de)
AT (1) ATE256185T1 (de)
AU (1) AU751151C (de)
CA (1) CA2301499C (de)
DE (1) DE69820449T2 (de)
DK (1) DK0996726T3 (de)
ES (1) ES2213295T3 (de)
PT (1) PT996726E (de)
WO (1) WO1999011782A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL134830A0 (en) * 2000-03-01 2001-05-20 Chay 13 Medical Res Group N V Peptides and immunostimulatory and anti-bacterial pharmaceutical compositions containing them
US20030166599A1 (en) * 2000-05-03 2003-09-04 Nalan Utku Uses of tgap7 for the modulation of leucocyte activation
AU2002221775B2 (en) * 2000-10-30 2006-11-23 Genpat77 Pharmacogenetics Ag Methods for obtaining inhibitors of t-cell membrane protein (TIRC7) ligand binding and uses thereof
US7026121B1 (en) 2001-06-08 2006-04-11 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
US6905827B2 (en) 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
WO2003025000A2 (en) * 2001-09-17 2003-03-27 Nalan Utku Peptides capable of modulating immune response
US20050118178A1 (en) * 2001-11-27 2005-06-02 Nalan Utku Use of t-cell immune response cdna7 (tirc7) in angiogenic and anti-angiogenic therapy
US7794715B2 (en) 2001-12-21 2010-09-14 Cellact Pharma Gmbh Anti-TIRC7 antibodies in therapy of inflammatory diseases
WO2003054019A2 (en) * 2001-12-21 2003-07-03 Genpat77 Pharmacogenetics Ag Therapeutic monoclonal anti-tirc7 antibodies for use in immune related and other diseases
AU2003208791A1 (en) * 2002-02-04 2003-09-02 Genpat77 Pharmacogenetics Ag Compositions and methods for modulation of effects on phagocyte and lymphoid cell populations employing TIRC7
WO2003091285A1 (en) * 2002-04-26 2003-11-06 Genpat77 Pharmacogenetics Ag Bispecific molecules for use in therapy and diagnosis of immune related and other diseases
AU2003233197A1 (en) * 2002-04-29 2003-11-17 Genpat77 Pharmacogenetics Ag Novel antibody binding tcr and tirc7 and its use in therapy and diagnosis
US20110183921A1 (en) * 2005-05-17 2011-07-28 Jojomed Gmbh Peptides capable of modulating the function of tirc7
EP1891444A2 (de) * 2005-05-17 2008-02-27 GenPat77 Pharmacogenetics AG Tirc7 als marker zur vorzeitigen erkennung einer immunsystem-aktivierung
DE202011103324U1 (de) 2011-07-12 2012-01-02 Nekonal S.A.R.L. Therapeutische anti-TIRC7 Antikörper für die Verwendung in Immun und anderen Krankheiten
WO2018029266A1 (en) 2016-08-09 2018-02-15 Nekonal S.A.R.L. Tirc7 based diagnostic and therapy of cancer
CA3033620A1 (en) 2016-08-10 2018-02-15 Nekonal S.A.R.L. Tirc7 based diagnostic and therapy of solid cancer
WO2021028579A1 (en) 2019-08-14 2021-02-18 Nekonal S.A.R.L. Method for producing engineered tirc7 specific t-regulatory cells (tregs)

Also Published As

Publication number Publication date
JP2001514852A (ja) 2001-09-18
DE69820449D1 (de) 2004-01-22
AU751151C (en) 2006-09-14
CA2301499A1 (en) 1999-03-11
AU9265498A (en) 1999-03-22
PT996726E (pt) 2004-04-30
ES2213295T3 (es) 2004-08-16
DE69820449T2 (de) 2005-03-10
EP1350848A3 (de) 2004-02-04
EP1350848A2 (de) 2003-10-08
DK0996726T3 (da) 2004-04-13
EP0996726A1 (de) 2000-05-03
JP4459435B2 (ja) 2010-04-28
EP0996726B1 (de) 2003-12-10
AU751151B2 (en) 2002-08-08
WO1999011782A1 (en) 1999-03-11
CA2301499C (en) 2010-01-26

Similar Documents

Publication Publication Date Title
ATE256185T1 (de) T-zell-membranprotein (tirc7), davon abgeleitete peptide und antikörper und ihre verwendungen
DE68916932D1 (de) Antimikrobielle peptide, zusammensetzungen, die diese enthalten, und verwendungen daraus.
DE59007517D1 (de) Neue proteine mit tnf-hemmender wirkung und ihre herstellung.
BG102983A (en) Extramembrane protein 106 polypeptide of moraxella catarrhalis, its gene sequence and application
DE60030450D1 (de) Von MUC-1 abgeleitete Peptide
NO20025153D0 (no) FremgangsmÕter og sammensetninger for Õ svekke formering av HIV-1
DE3588254D1 (de) Gag-Antigen und dessen Verwendung zum Nachweis von LAV-Infektion, sowie in immunogenen Zusammensetzungen
ATE355074T1 (de) Hybrid aus interferon-alpha und immunglobulin fc- fragment verbunden durch ein nicht immunogenes peptid
DE60138558D1 (de) Peptid aus hsp70 welches nk zellaktivtät stimuliert und seine verwendung
ATE331037T1 (de) Isoliertes frpb nukleinsäuremolekül und entsprechende impfstoff
RU2214273C2 (ru) ДНК-ПОСЛЕДОВАТЕЛЬНОСТИ, КОДИРУЮЩИЕ ЧЕЛОВЕЧЕСКИЕ ПРОТЕИНЫ Tx И Ty, РОДСТВЕННЫЕ КОНВЕРГИРУЮЩЕМУ ИНТЕРЛЕЙКИН-1-β ФЕРМЕНТУ
WO1999042127A3 (en) Receptor derived peptides as modulators of receptor activity
DK1436320T3 (da) T-celle-epitoper af cyn D 1-allergenet fra bermudagræspollen
DK0972781T3 (da) Protein S-polypeptider og anvendelser deraf
ATE143974T1 (de) Peptide des hiv-gag proteins, ihre herstellung und verwendung
EP0656010B8 (de) Verwendung von Peptiden welche eine Immunantwort bewirken zur Herstellung von Medikamenten zur Induzierung der Immunsuppression.
DE69928947D1 (de) Moraxella catarrhalis basb034 polypeptide und verwendungen davon
ATE338063T1 (de) Diagnostische verwendungen des t-zell proteins tzon7, der davon abgeleiteten peptide und des antikörpers
DE60335278D1 (de) Hen peptiden zur modulierung von ncam funktionen
AR036104A1 (es) Un receptor acoplado a la proteina g, gave3
TH31634A (th) เพพไทด์ชนิดใหม่ที่เหมาะสมสำหรับใช้ในการบำบัดรักษาที่กดภูมิคุ้มกันที่มีความจำเพาะต่อแอนติเจน
CY1109617T1 (el) Ενα πεπτιδιο hsp70 που διεγειρει τη δραστηριοτητα φυσικων φονικων κυτταρων (νκ) και χρησεις αυτου
TH62973A (th) กรดนิวคลีอิค และพอลิเพพไทด์ตัวรับชนิดใหม่

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0996726

Country of ref document: EP