ATE256191T1 - Ein pilz, in dem das area-gen verändert ist, und ein area-gen aus aspergillus oryzae - Google Patents

Ein pilz, in dem das area-gen verändert ist, und ein area-gen aus aspergillus oryzae

Info

Publication number
ATE256191T1
ATE256191T1 AT95922443T AT95922443T ATE256191T1 AT E256191 T1 ATE256191 T1 AT E256191T1 AT 95922443 T AT95922443 T AT 95922443T AT 95922443 T AT95922443 T AT 95922443T AT E256191 T1 ATE256191 T1 AT E256191T1
Authority
AT
Austria
Prior art keywords
area gene
pct
aspergillus oryzae
modified
mushroom
Prior art date
Application number
AT95922443T
Other languages
English (en)
Inventor
Tove Christensen
Michael J Hynes
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of ATE256191T1 publication Critical patent/ATE256191T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C12N9/6481—Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/62—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from Aspergillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6427—Chymotrypsins (3.4.21.1; 3.4.21.2); Trypsin (3.4.21.4)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
AT95922443T 1994-06-17 1995-06-19 Ein pilz, in dem das area-gen verändert ist, und ein area-gen aus aspergillus oryzae ATE256191T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK71794 1994-06-17
PCT/DK1995/000254 WO1995035385A1 (en) 1994-06-17 1995-06-19 A FUNGUS WHEREIN THE areA GENE HAS BEEN MODIFIED AND AN areA GENE FROM ASPERGILLUS ORYZAE

Publications (1)

Publication Number Publication Date
ATE256191T1 true ATE256191T1 (de) 2003-12-15

Family

ID=8096735

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95922443T ATE256191T1 (de) 1994-06-17 1995-06-19 Ein pilz, in dem das area-gen verändert ist, und ein area-gen aus aspergillus oryzae

Country Status (10)

Country Link
US (1) US6025185A (de)
EP (1) EP0770139B1 (de)
JP (1) JPH10501414A (de)
CN (1) CN1253574C (de)
AT (1) ATE256191T1 (de)
AU (1) AU2733895A (de)
DE (1) DE69532283T2 (de)
DK (1) DK0770139T3 (de)
FI (1) FI965031L (de)
WO (1) WO1995035385A1 (de)

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WO1997022705A1 (en) * 1995-12-15 1997-06-26 Novo Nordisk A/S A FUNGUNS WHEREIN THE areA, pepC AND/OR pepE GENES HAVE BEEN INACTIVATED
CN100432099C (zh) 1996-07-05 2008-11-12 诺沃奇梅兹有限公司 转录因子
US5811381A (en) * 1996-10-10 1998-09-22 Mark A. Emalfarb Cellulase compositions and methods of use
US7883872B2 (en) * 1996-10-10 2011-02-08 Dyadic International (Usa), Inc. Construction of highly efficient cellulase compositions for enzymatic hydrolysis of cellulose
DE69729085T2 (de) * 1997-07-05 2005-04-21 Nestle Sa Gesteigerte Expression proteolytischer Enzyme in ...
CN1329667B (zh) * 1998-10-05 2014-05-28 诺维信公司 在制备多肽的方法中有效的真菌转录激活因子
US6806062B1 (en) 1998-10-05 2004-10-19 Novozymes A/S Fungal transcriptional activator useful in methods for producing polypeptides
KR100618495B1 (ko) * 1998-10-06 2006-08-31 마크 아론 에말파브 섬유상의 진균성 숙주 영역에서의 형질전환 시스템:크리소스포륨속에서
JP5043254B2 (ja) 1998-10-26 2012-10-10 ノボザイムス アクティーゼルスカブ 糸状面細胞内の問題のｄｎａライブラリーの作製及びスクリーニング
DE60142226D1 (de) * 2000-03-14 2010-07-08 Novozymes As Pilz transkriptionsaktivator zur verwendung in verfahren zur herstellung von polypeptiden
WO2008073914A2 (en) 2006-12-10 2008-06-19 Dyadic International Inc. Expression and high-throughput screening of complex expressed dna libraries in filamentous fungi
US9862956B2 (en) 2006-12-10 2018-01-09 Danisco Us Inc. Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi
CA2736661A1 (en) * 2007-09-07 2009-03-12 Dyadic International, Inc. Novel fungal enzymes
CN102482652B (zh) 2009-06-02 2014-12-17 诺维信股份有限公司 具有纤维二糖水解酶活性的多肽和编码该多肽的多核苷酸
CA2767169A1 (en) 2009-07-07 2011-01-13 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
CN102648276A (zh) 2009-09-29 2012-08-22 诺维信股份有限公司 具有木聚糖酶活性的多肽和编码该多肽的多核苷酸
EP2483295B1 (de) 2009-09-29 2015-11-25 Novozymes Inc. Polypeptide mit cellulolytisch verstärkender wirkung und diese kodierende polynukleotide
BR112012007375A2 (pt) 2009-09-30 2016-11-22 Novozymes As polipeptídeo isolado, polinucleotídeo isolado, métodos para produzir um polipeptídeo, para produzir um mutante de uma célula precursora, para inibir a expressão de um polipeptídeo, para produzir uma proteína, para degradar ou converter um material celulósico, para produzir um produto de fermentação e para fermentar um material celulósico, planta transgênica, parte de planta ou célula de planta transformada, molécula de rna inibitória de filamento duplo, e, composição detergente
BR112012008291A8 (pt) 2009-11-06 2019-05-21 Novozymes Inc composição de enzima, célula hospedeira recombinante, e, métodos de produzir uma composição de enzima, para degradar ou converter um material celulósico, para produzir um produto de fermentação e de fermentar um material celulósico
WO2012059053A1 (en) 2010-11-04 2012-05-10 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
BR112013009026A2 (pt) 2010-11-12 2016-07-12 Novozymes Inc polipeptídeo isolado, célula hospedeira recombinante, métodos para produzir um polipeptídeo, um mutante de uma célula precursora, uma proteína, e um produto de fermentação, para inibir a expressão de um polipeptídeo, para degradar ou converter um material celulósico, e método para fermentar um material celulósico, planta transgênica, parte de planta ou célula de planta, molécula de rna inibidora de filamento duplo, polinucleotídeo isolado, e, formulação de caldo integral ou composição de cultura de célula
EP2678352B1 (de) 2011-02-23 2017-12-06 Novozymes, Inc. Polypeptide mit verstärkter zelluloseabbauender wirkung und dafür kodierende polynukleotide
EP2689011B1 (de) 2011-03-25 2017-10-25 Novozymes A/S Verfahren zum abbau oder zur umwandlung von zellulose
WO2012149344A1 (en) 2011-04-29 2012-11-01 Novozymes, Inc. Methods for enhancing the degradation or conversion of cellulosic material
WO2013064075A1 (en) 2011-10-31 2013-05-10 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EP3342860A1 (de) 2011-11-22 2018-07-04 Novozymes, Inc. Polypeptide mit beta-xylosidase-aktivität und dafür codierende polynukleotide
BR112014012417A2 (pt) 2011-12-01 2017-06-06 Novozymes Inc polipeptídeo e polinucleotídeo isolados, célula hospedeira recombinante, métodos para a produção de um polipeptídeo, de um mutante de uma célula de origem, e de uma proteína, e para a inibição da expressão de um polipeptídeo, planta transgênica, parte da planta ou célula de planta, molécula de rna, processos para degradar ou converter um material celulósico ou contendo xilano, para produzir um produto de fermentação, e de fermentação de um material celulósico ou contendo xilano, e, formulação de caldo integral ou composição de cultura de células
EP3272862A1 (de) 2011-12-16 2018-01-24 Novozymes, Inc. Polypeptide mit laccaseaktivität und dafür kodierende polynukleotide
BR112014014697A2 (pt) 2011-12-19 2020-10-27 Novozymes, Inc. polipeptídeo isolado, composição, polinucleotídeo isolado, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, métodos para produzir um polipeptídeo e uma proteína, para gerar oxigênio molecular, e para remover peróxido de hidrogênio do tecido, processos para degradar ou converter um material celulósico, e para produzir um produto de fermentação, e, formulação de caldo integral ou composição de cultura de células
EP2800809B1 (de) 2012-01-05 2018-03-07 Glykos Finland Oy Filamentöse pilzzellen mit proteasemangel und verwendungsverfahren dafür
US9695454B2 (en) 2012-05-23 2017-07-04 Glykos Finland Oy Production of fucosylated glycoproteins
EP2938628A4 (de) 2012-12-24 2016-10-19 Novozymes As Polypeptide mit endoglucanaseaktivität und polynukleotide zur codierung davon
KR20160035587A (ko) 2013-07-10 2016-03-31 노파르티스 아게 복수개의 프로테아제 결핍 사상형 진균 세포들 및 그의 이용방법
WO2015025055A1 (en) 2013-08-23 2015-02-26 Novozymes A/S Regulated pepc expression
CN108064266A (zh) 2014-07-21 2018-05-22 格利科斯芬兰公司 在丝状真菌中具有哺乳动物样n-聚糖的糖蛋白的制备

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Also Published As

Publication number Publication date
AU2733895A (en) 1996-01-15
EP0770139B1 (de) 2003-12-10
FI965031A0 (fi) 1996-12-16
DK0770139T3 (da) 2004-04-13
FI965031A7 (fi) 1996-12-16
FI965031L (fi) 1996-12-16
CN1253574C (zh) 2006-04-26
JPH10501414A (ja) 1998-02-10
EP0770139A1 (de) 1997-05-02
WO1995035385A1 (en) 1995-12-28
DE69532283D1 (de) 2004-01-22
DE69532283T2 (de) 2004-09-23
CN1150824A (zh) 1997-05-28
US6025185A (en) 2000-02-15

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