ATE257326T1 - Verbesserte lager- und haltbarkeit von blutprodukten - Google Patents

Verbesserte lager- und haltbarkeit von blutprodukten

Info

Publication number
ATE257326T1
ATE257326T1 AT98917604T AT98917604T ATE257326T1 AT E257326 T1 ATE257326 T1 AT E257326T1 AT 98917604 T AT98917604 T AT 98917604T AT 98917604 T AT98917604 T AT 98917604T AT E257326 T1 ATE257326 T1 AT E257326T1
Authority
AT
Austria
Prior art keywords
blood products
shelf life
improved storage
blood cells
red blood
Prior art date
Application number
AT98917604T
Other languages
English (en)
Inventor
Secondo Dottori
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of ATE257326T1 publication Critical patent/ATE257326T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • A61L2/10—Ultraviolet [UV] radiation
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • A61L2/081—Gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials
    • A61L2103/09—Blood or products thereof

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • External Artificial Organs (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Packages (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
AT98917604T 1997-04-16 1998-04-15 Verbesserte lager- und haltbarkeit von blutprodukten ATE257326T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/840,765 US6482585B2 (en) 1997-04-16 1997-04-16 Storage and maintenance of blood products including red blood cells and platelets
PCT/IT1998/000086 WO1998046073A1 (en) 1997-04-16 1998-04-15 Improved storage and maintenance of blood products

Publications (1)

Publication Number Publication Date
ATE257326T1 true ATE257326T1 (de) 2004-01-15

Family

ID=25283169

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98917604T ATE257326T1 (de) 1997-04-16 1998-04-15 Verbesserte lager- und haltbarkeit von blutprodukten

Country Status (20)

Country Link
US (2) US6482585B2 (de)
EP (1) EP0975214B1 (de)
JP (1) JP4467649B2 (de)
KR (1) KR100508408B1 (de)
CN (2) CN1252687A (de)
AT (1) ATE257326T1 (de)
AU (1) AU739842B2 (de)
BR (1) BR9808911B1 (de)
CA (1) CA2286721A1 (de)
CZ (1) CZ298671B6 (de)
DE (1) DE69821002T2 (de)
DK (1) DK0975214T3 (de)
ES (1) ES2212288T3 (de)
HU (1) HUP0001936A3 (de)
IL (1) IL132271A (de)
NZ (1) NZ500534A (de)
PL (1) PL192684B1 (de)
PT (1) PT975214E (de)
SK (1) SK284688B6 (de)
WO (1) WO1998046073A1 (de)

Families Citing this family (42)

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US6403124B1 (en) * 1997-04-16 2002-06-11 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Storage and maintenance of blood products including red blood cells and platelets
US6482585B2 (en) * 1997-04-16 2002-11-19 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Storage and maintenance of blood products including red blood cells and platelets
MXPA02003635A (es) * 1999-10-11 2002-10-23 Sigma Tau Ind Farmaceuti Uso de l-carnitina y sus derivados de alcanoilo como agentes osmoticos en soluciones para uso medico.
US8828226B2 (en) 2003-03-01 2014-09-09 The Trustees Of Boston University System for assessing the efficacy of stored red blood cells using microvascular networks
RU2245145C1 (ru) * 2003-10-01 2005-01-27 Российский государственный медицинский университет Средство нормализации агрегационных свойств тромбоцитов и эритроцитов и морфоденситометрических характеристик эритроцитов
US20070077237A1 (en) * 2003-10-09 2007-04-05 Udi Damari Method for freezing, thawing and transplantation of viable cartilage
WO2005072523A2 (en) * 2004-02-02 2005-08-11 I.M.T. Interface Multigrad Technology Ltd. Biological material and methods and solutions for preservation thereof
EP1711214A1 (de) * 2004-02-02 2006-10-18 Interface Multigrad Technology (IMT) Ltd. Vorrichtung zum gerichteten kühlen von biomasse
US7892726B2 (en) * 2004-06-07 2011-02-22 Core Dynamics Limited Method for sterilizing lyophilized eukaryotic anuclear cells with gamma irradiation
EP1778007A1 (de) * 2004-08-12 2007-05-02 I.M.T. Interface Multigrad Technology Ltd. Verfahren und gerät zum einfrieren bzw. auftauen von biologischem material
EP1850661A2 (de) * 2005-02-22 2007-11-07 Interface Multigrad Technology (IMT) Ltd. Konservierter lebensfähiger knorpel, verfahren zu seiner konservierung, sowie hierfür verwendete(s) system und geräte
FR2884717B1 (fr) * 2005-04-25 2009-07-03 Erytech Pharma Soc Par Actions Erythrocytes renfermant de l'arginine deiminase
EP1909565A2 (de) * 2005-08-03 2008-04-16 Interface Multigrad Technology (IMT) Ltd. Somatische zellen für die zelltherapie
US7462485B2 (en) * 2005-10-07 2008-12-09 Glaser Lawrence F Modified erythrocytes and uses thereof
US8835104B2 (en) 2007-12-20 2014-09-16 Fenwal, Inc. Medium and methods for the storage of platelets
US20090202978A1 (en) * 2008-02-13 2009-08-13 Ginadi Shaham Method and apparatus for freezing of a biological material
US8871434B2 (en) * 2008-03-21 2014-10-28 Fenwal, Inc. Red blood cell storage medium for extended storage
US8968992B2 (en) * 2008-03-21 2015-03-03 Fenwal, Inc. Red blood cell storage medium for extended storage
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US9199016B2 (en) 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
BR112012008683B8 (pt) 2009-10-12 2022-11-08 Hemanext Inc dispositivo de armazenagem de sangue para armazenar sangue depletado de oxigênio e dióxido de carbono, dispositivo de depleção de oxigênio e dióxido de carbono, método para remover oxigênio e dióxido de carbono de hemácias, sistema de armazenagem de sangue, dispositivo de armazenagem de sangue, método para remover oxigênio de hemácias e método para aumentar os níveis de adenosina trifosfato (atp) nas hemácias
US12089589B2 (en) 2009-10-12 2024-09-17 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
CN102905522A (zh) 2009-10-12 2013-01-30 新健康科学股份有限公司 用于从红细胞中除去氧的氧消耗装置和方法
US11864553B2 (en) 2009-10-23 2024-01-09 Fenwal, Inc. Methods and systems for providing red blood cell products with reduced plasma
WO2012027582A1 (en) 2010-08-25 2012-03-01 New Health Sciences Method for enhancing red blood cell quality and survival during storage
EP4218412A1 (de) 2010-11-05 2023-08-02 Hemanext Inc. Bestrahlung von roten blutkörperchen und anaerobe lagerung
CA2826969C (en) 2010-11-29 2019-02-19 New York Blood Center, Inc. Method of blood pooling and storage
US9067004B2 (en) 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
WO2012139017A1 (en) 2011-04-07 2012-10-11 Fenwal, Inc. Automated methods and systems for providing platelet concentrates with reduced residual plasma volumes and storage media for such platelet concentrates
JP2014518283A (ja) * 2011-07-05 2014-07-28 ニュー・ヘルス・サイエンシーズ・インコーポレイテッド 赤血球の長期保存システムおよび使用方法
AU2012294269B2 (en) 2011-08-10 2016-11-24 Hemanext Inc. Integrated leukocyte, oxygen and/or CO2 depletion, and plasma separation filter device
CA2902061C (en) 2013-02-28 2023-08-08 New Health Sciences, Inc. Gas depletion and gas addition devices for blood treatment
KR20250033333A (ko) 2015-03-10 2025-03-07 헤마넥스트 인코포레이티드 산소 감소 1회용 키트, 장치 및 이의 사용 방법
BR122022005103B1 (pt) 2015-04-23 2023-03-14 Hemanext Inc Dispositivo de armazenamento de sangue para armazenar sangue depletado de oxigênio e método para armazenar sangue depletado de oxigênio
PT3297641T (pt) 2015-05-18 2025-10-09 Hemanext Inc Métodos de armazenamento de sangue total e respetivas composições
CN109195632A (zh) 2016-05-27 2019-01-11 新健康科学股份有限公司 厌氧血液储存和病原体失活方法
DE102017218847A1 (de) 2017-10-23 2019-04-25 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur Verbesserung der Stabilität von Blut und Blutprodukten
WO2021108806A1 (en) * 2019-11-29 2021-06-03 Rutgers, The State University Of New Jersey Compositions, kits and methods for storage of blood products and methods of use thereof
EP4065690A1 (de) 2019-11-29 2022-10-05 Rutgers, the State University of New Jersey Verfahren zum isolieren von nabelblutplasmaprodukten, gewebe- und zellexosomen und zusammensetzungen und verfahren zur verwendung davon
CN116115753A (zh) * 2021-11-15 2023-05-16 上海循曜生物科技有限公司 一种新的改善血小板质量的方法
CN114600872A (zh) * 2022-04-13 2022-06-10 西安北光医学生物技术有限公司 一种细胞、组织或器官的抗损伤保存的方法及保存系统
AU2024244509A1 (en) * 2023-03-31 2025-10-02 Hemerus Medical, Llc Formulations and methods for collecting and storing blood and blood products

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US5376524A (en) 1991-04-01 1994-12-27 Thomas Jefferson University Platelet storage medium containing acetate and phosphate
IT1261695B (it) * 1993-06-02 1996-05-29 Sigma Tau Ind Farmaceuti Impiego di l-carnitina e alcanoil l-carnitine nella conservazione del sangue per trasfusioni e soluzioni stabilizzatrici che le contengono.
US5362442A (en) * 1993-07-22 1994-11-08 2920913 Canada Inc. Method for sterilizing products with gamma radiation
AU6267496A (en) * 1995-06-07 1996-12-30 Steritech, Inc. Methods of inactivating leukocytes and inhibiting cytokine p roduction in blood products
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IT1277953B1 (it) * 1995-12-21 1997-11-12 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o una alcanoil l- carnitina e un acido poliinsaturo della serie 3-omega utile per
US6482585B2 (en) * 1997-04-16 2002-11-19 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Storage and maintenance of blood products including red blood cells and platelets
US6010890A (en) * 1997-04-29 2000-01-04 New York Blood Center, Inc. Method for viral inactivation and compositions for use in same

Also Published As

Publication number Publication date
BR9808911A (pt) 2000-08-01
EP0975214A1 (de) 2000-02-02
CA2286721A1 (en) 1998-10-22
EP0975214B1 (de) 2004-01-07
PT975214E (pt) 2004-05-31
DE69821002T2 (de) 2004-07-08
CZ368199A3 (cs) 2000-04-12
IL132271A0 (en) 2001-03-19
JP4467649B2 (ja) 2010-05-26
US6482585B2 (en) 2002-11-19
JP2001523225A (ja) 2001-11-20
AU739842B2 (en) 2001-10-18
KR100508408B1 (ko) 2005-08-17
HUP0001936A3 (en) 2001-03-28
HK1025477A1 (en) 2000-11-17
PL336294A1 (en) 2000-06-19
SK284688B6 (sk) 2005-09-08
PL192684B1 (pl) 2006-11-30
DE69821002D1 (de) 2004-02-12
ES2212288T3 (es) 2004-07-16
DK0975214T3 (da) 2004-05-10
US20030022228A1 (en) 2003-01-30
AU7078198A (en) 1998-11-11
CN1698430A (zh) 2005-11-23
US20010049089A1 (en) 2001-12-06
SK142799A3 (en) 2000-05-16
NZ500534A (en) 2001-05-25
BR9808911B1 (pt) 2010-09-21
CZ298671B6 (cs) 2007-12-19
WO1998046073A1 (en) 1998-10-22
CN1252687A (zh) 2000-05-10
IL132271A (en) 2005-12-18
US6960428B2 (en) 2005-11-01
KR20010006464A (ko) 2001-01-26
HUP0001936A2 (hu) 2000-10-28

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