ATE259659T1 - Zusammensetzung die mindestens ein stickstoffmonoxid-synthase inhibitor und mindestens ein phospholipase a2 inhibitor enthält zur herstellung eines medikamentes - Google Patents
Zusammensetzung die mindestens ein stickstoffmonoxid-synthase inhibitor und mindestens ein phospholipase a2 inhibitor enthält zur herstellung eines medikamentesInfo
- Publication number
- ATE259659T1 ATE259659T1 AT00974645T AT00974645T ATE259659T1 AT E259659 T1 ATE259659 T1 AT E259659T1 AT 00974645 T AT00974645 T AT 00974645T AT 00974645 T AT00974645 T AT 00974645T AT E259659 T1 ATE259659 T1 AT E259659T1
- Authority
- AT
- Austria
- Prior art keywords
- inhibitor
- phospholipase
- nitrogen monoxide
- medication
- producing
- Prior art date
Links
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical group O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 title abstract 4
- 108010014865 PLIalpha Proteins 0.000 title 1
- 229940123898 Phospholipase A2 inhibitor Drugs 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000003358 phospholipase A2 inhibitor Substances 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 abstract 4
- 239000000126 substance Substances 0.000 abstract 4
- 102000006447 Phospholipases A2 Human genes 0.000 abstract 3
- 108010058864 Phospholipases A2 Proteins 0.000 abstract 3
- 102000008299 Nitric Oxide Synthase Human genes 0.000 abstract 2
- 108010021487 Nitric Oxide Synthase Proteins 0.000 abstract 2
- 230000007170 pathology Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
-
- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Otolaryngology (AREA)
- Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9913859A FR2800615B1 (fr) | 1999-11-05 | 1999-11-05 | Produit comprenant au moins une substance inhibitrice des no synthases en association avec au moins une substance inhibitrice des phospholipases a2 |
| PCT/FR2000/003066 WO2001032216A2 (fr) | 1999-11-05 | 2000-11-03 | Produit comprenant au moins une substance inhibitrice des no synthases en association avec au moins une substance inhibitrice des phospholipases a2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE259659T1 true ATE259659T1 (de) | 2004-03-15 |
Family
ID=9551744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00974645T ATE259659T1 (de) | 1999-11-05 | 2000-11-03 | Zusammensetzung die mindestens ein stickstoffmonoxid-synthase inhibitor und mindestens ein phospholipase a2 inhibitor enthält zur herstellung eines medikamentes |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6872738B1 (de) |
| EP (1) | EP1233786B1 (de) |
| JP (1) | JP2003513050A (de) |
| AT (1) | ATE259659T1 (de) |
| AU (1) | AU1287001A (de) |
| CA (1) | CA2389661A1 (de) |
| CZ (1) | CZ20021549A3 (de) |
| DE (1) | DE60008415T2 (de) |
| DK (1) | DK1233786T3 (de) |
| ES (1) | ES2215746T3 (de) |
| FR (1) | FR2800615B1 (de) |
| HU (1) | HUP0203348A3 (de) |
| PL (1) | PL202997B1 (de) |
| PT (1) | PT1233786E (de) |
| RU (1) | RU2256465C2 (de) |
| WO (1) | WO2001032216A2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU228783B1 (en) | 2001-07-26 | 2013-05-28 | Greenearth Cleaning | Dry cleaning apparatus and method capable of utilizing a siloxane solvent |
| US8586516B2 (en) * | 2007-01-19 | 2013-11-19 | Afton Chemical Corporation | High TBN / low phosphorus economic STUO lubricants |
| JP2023542298A (ja) * | 2020-09-11 | 2023-10-06 | プルモシム セラピューティクス リミテッド ライアビリティ カンパニー | 肺高血圧症を治療又は予防する組成物及び方法 |
| CN113730409B (zh) * | 2021-11-01 | 2022-06-14 | 济南市中心医院 | 奎纳克林在制备治疗肺纤维化药物中的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5229403A (en) * | 1990-07-10 | 1993-07-20 | Ishihara Sangyo Kaisha Ltd. | Diaminotrifluoromethylpyridine derivatives and phospholipase A2 inhibitor containing them |
| CZ29996A3 (en) * | 1993-08-12 | 1996-09-11 | Astra Ab | Amidine derivatives with activities of nitrogen oxide sythetase |
| US6335445B1 (en) * | 1997-03-24 | 2002-01-01 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them |
-
1999
- 1999-11-05 FR FR9913859A patent/FR2800615B1/fr not_active Expired - Fee Related
-
2000
- 2000-11-03 RU RU2002114694/15A patent/RU2256465C2/ru not_active IP Right Cessation
- 2000-11-03 PL PL355285A patent/PL202997B1/pl not_active IP Right Cessation
- 2000-11-03 HU HU0203348A patent/HUP0203348A3/hu unknown
- 2000-11-03 CZ CZ20021549A patent/CZ20021549A3/cs unknown
- 2000-11-03 PT PT00974645T patent/PT1233786E/pt unknown
- 2000-11-03 DK DK00974645T patent/DK1233786T3/da active
- 2000-11-03 DE DE60008415T patent/DE60008415T2/de not_active Expired - Lifetime
- 2000-11-03 AU AU12870/01A patent/AU1287001A/en not_active Abandoned
- 2000-11-03 US US10/111,139 patent/US6872738B1/en not_active Expired - Fee Related
- 2000-11-03 CA CA002389661A patent/CA2389661A1/fr not_active Abandoned
- 2000-11-03 WO PCT/FR2000/003066 patent/WO2001032216A2/fr not_active Ceased
- 2000-11-03 AT AT00974645T patent/ATE259659T1/de not_active IP Right Cessation
- 2000-11-03 EP EP00974645A patent/EP1233786B1/de not_active Expired - Lifetime
- 2000-11-03 JP JP2001534420A patent/JP2003513050A/ja active Pending
- 2000-11-03 ES ES00974645T patent/ES2215746T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001032216A3 (fr) | 2002-03-28 |
| FR2800615A1 (fr) | 2001-05-11 |
| RU2002114694A (ru) | 2004-01-10 |
| PL202997B1 (pl) | 2009-08-31 |
| US6872738B1 (en) | 2005-03-29 |
| WO2001032216A2 (fr) | 2001-05-10 |
| PL355285A1 (en) | 2004-04-05 |
| PT1233786E (pt) | 2004-07-30 |
| FR2800615B1 (fr) | 2002-05-03 |
| HUP0203348A3 (en) | 2005-03-29 |
| CA2389661A1 (fr) | 2001-05-10 |
| EP1233786B1 (de) | 2004-02-18 |
| RU2256465C2 (ru) | 2005-07-20 |
| CZ20021549A3 (cs) | 2002-11-13 |
| HUP0203348A2 (hu) | 2003-02-28 |
| EP1233786A2 (de) | 2002-08-28 |
| ES2215746T3 (es) | 2004-10-16 |
| JP2003513050A (ja) | 2003-04-08 |
| AU1287001A (en) | 2001-05-14 |
| DK1233786T3 (da) | 2004-06-21 |
| DE60008415T2 (de) | 2004-12-16 |
| DE60008415D1 (de) | 2004-03-25 |
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