ATE261454T1 - Verfahren zur herstellung von vernetzter hyaluronsäure - Google Patents

Verfahren zur herstellung von vernetzter hyaluronsäure

Info

Publication number: ATE261454T1
Authority: AT; Austria
Prior art keywords: hyaluronic acid; linked hyaluronic; producing cross; dvs; salt
Prior art date: 1998-02-27

Application number

AT98200620T

Other languages

English (en)

Inventor

Der Tuin Everhardus Van

Arie Cornelis Besemer

Original Assignee

Stichting Hippomedics

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-02-27

Filing date

1998-02-27

Publication date

2004-03-15

1998-02-27 Application filed by Stichting Hippomedics filed Critical Stichting Hippomedics

2004-03-15 Application granted granted Critical

2004-03-15 Publication of ATE261454T1 publication Critical patent/ATE261454T1/de

Links

KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title abstract 6
229920002674 hyaluronan Polymers 0.000 title abstract 6
229960003160 hyaluronic acid Drugs 0.000 title abstract 6
238000004519 manufacturing process Methods 0.000 title 1
AFOSIXZFDONLBT-UHFFFAOYSA-N divinyl sulfone Chemical compound C=CS(=O)(=O)C=C AFOSIXZFDONLBT-UHFFFAOYSA-N 0.000 abstract 3
239000007864 aqueous solution Substances 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/042—Polysaccharides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Polymers & Plastics (AREA)
Surgery (AREA)
Biochemistry (AREA)
Materials Engineering (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
Heart & Thoracic Surgery (AREA)
Engineering & Computer Science (AREA)
Vascular Medicine (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT98200620T 1998-02-27 1998-02-27 Verfahren zur herstellung von vernetzter hyaluronsäure ATE261454T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP98200620A EP0939086B1 (de)	1998-02-27	1998-02-27	Verfahren zur Herstellung von vernetzter Hyaluronsäure

Publications (1)

Publication Number	Publication Date
ATE261454T1 true ATE261454T1 (de)	2004-03-15

Family

ID=8233426

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98200620T ATE261454T1 (de)	1998-02-27	1998-02-27	Verfahren zur herstellung von vernetzter hyaluronsäure

Country Status (6)

Country	Link
EP (1)	EP0939086B1 (de)
AT (1)	ATE261454T1 (de)
DE (1)	DE69822285T2 (de)
DK (1)	DK0939086T3 (de)
ES (1)	ES2217496T3 (de)
PT (1)	PT939086E (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6521223B1 (en) *	2000-02-14	2003-02-18	Genzyme Corporation	Single phase gels for the prevention of adhesions
WO2002022139A1 (en) *	2000-09-14	2002-03-21	Robert Theiler	Intraarticular agent for the treatment of osteoarthritis
US20060246137A1 (en) *	2003-07-30	2006-11-02	Laurence Hermitte	Complex matrix for biomedical use
ES2706848T3 (es)	2004-07-06	2019-04-01	Zymogenetics Inc	Composición farmacéutica que comprende FGF18 y antagonista de IL-1 y método de uso
CN104689460B (zh) *	2004-12-30	2018-03-13	建新公司	用于关节内粘弹性补充的方案
US20070202084A1 (en)	2005-12-14	2007-08-30	Anika Therapeutics, Inc.	Bioabsorbable implant of hyaluronic acid derivative for treatment of osteochondral and chondral defects
EP2386306A1 (de)	2006-12-06	2011-11-16	Seikagaku Corporation	Pharmazeutischer Wirkstoff mit lang anhaltendem Effekt bei der Behandlung von arthritischen Störungen
PT2236523T (pt) *	2009-03-30	2018-03-21	Scivision Biotech Inc	Método para produzir ácido hialurónico reticulado
US9371402B2 (en)	2009-04-09	2016-06-21	Scivision Biotech Inc.	Method for producing cross-linked hyaluronic acid
AU2010276574B2 (en) *	2009-07-30	2015-08-20	Carbylan Therapeutics, Inc.	Modified hyaluronic acid polymer compositions and related methods
JO3008B1 (ar)	2009-08-13	2016-09-05	Seikagaku Kogyo Co Ltd	تركيب صيدلي لتخفيف الألم
CN101829365B (zh) *	2010-04-13	2013-04-17	杭州市第一人民医院	一种巩膜外加压生物复合材料及制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1238043A (en) *	1983-12-15	1988-06-14	Endre A. Balazs	Water insoluble preparations of hyaluronic acid and processes therefor
US4582865A (en) *	1984-12-06	1986-04-15	Biomatrix, Inc.	Cross-linked gels of hyaluronic acid and products containing such gels

1998
- 1998-02-27 PT PT98200620T patent/PT939086E/pt unknown
- 1998-02-27 ES ES98200620T patent/ES2217496T3/es not_active Expired - Lifetime
- 1998-02-27 EP EP98200620A patent/EP0939086B1/de not_active Expired - Lifetime
- 1998-02-27 AT AT98200620T patent/ATE261454T1/de active
- 1998-02-27 DK DK98200620T patent/DK0939086T3/da active
- 1998-02-27 DE DE69822285T patent/DE69822285T2/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE69822285D1 (de)	2004-04-15
ES2217496T3 (es)	2004-11-01
EP0939086B1 (de)	2004-03-10
DE69822285T2 (de)	2005-01-27
PT939086E (pt)	2004-07-30
EP0939086A1 (de)	1999-09-01
DK0939086T3 (da)	2004-04-13

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2004-11-15

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