ATE262892T1 - Verwendung einer zusammensetzung enthaltend capsaicin oder resiniferatoxin zur behandlung des reizdarmsyndroms - Google Patents

Verwendung einer zusammensetzung enthaltend capsaicin oder resiniferatoxin zur behandlung des reizdarmsyndroms

Info

Publication number: ATE262892T1
Authority: AT; Austria
Prior art keywords: irgitable; resiniferatoxin; treatment; composition containing; bowel syndrome
Prior art date: 1997-06-10

Application number

AT98925862T

Other languages

English (en)

Inventor

Fiona Kate Gardiner

Original Assignee

Reckitt Benckiser Healthcare

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-10

Filing date

1998-06-08

Publication date

2004-04-15

1998-06-08 Application filed by Reckitt Benckiser Healthcare filed Critical Reckitt Benckiser Healthcare

2004-04-15 Application granted granted Critical

2004-04-15 Publication of ATE262892T1 publication Critical patent/ATE262892T1/de

Links

YKPUWZUDDOIDPM-SOFGYWHQSA-N capsaicin Chemical compound COC1=CC(CNC(=O)CCCC\C=C\C(C)C)=CC=C1O YKPUWZUDDOIDPM-SOFGYWHQSA-N 0.000 title 2
IKYCZSUNGFRBJS-UHFFFAOYSA-N Euphorbia factor RL9 = U(1) = Resiniferatoxin Natural products COC1=CC(O)=CC(CC(=O)OCC=2CC3(O)C(=O)C(C)=CC3C34C(C)CC5(OC(O4)(CC=4C=CC=CC=4)OC5C3C=2)C(C)=C)=C1 IKYCZSUNGFRBJS-UHFFFAOYSA-N 0.000 title 1
229960002504 capsaicin Drugs 0.000 title 1
235000017663 capsaicin Nutrition 0.000 title 1
DSDNAKHZNJAGHN-UHFFFAOYSA-N resinferatoxin Natural products C1=C(O)C(OC)=CC(CC(=O)OCC=2CC3(O)C(=O)C(C)=CC3C34C(C)CC5(OC(O4)(CC=4C=CC=CC=4)OC5C3C=2)C(C)=C)=C1 DSDNAKHZNJAGHN-UHFFFAOYSA-N 0.000 title 1
DSDNAKHZNJAGHN-MXTYGGKSSA-N resiniferatoxin Chemical compound C1=C(O)C(OC)=CC(CC(=O)OCC=2C[C@]3(O)C(=O)C(C)=C[C@H]3[C@@]34[C@H](C)C[C@@]5(O[C@@](O4)(CC=4C=CC=CC=4)O[C@@H]5[C@@H]3C=2)C(C)=C)=C1 DSDNAKHZNJAGHN-MXTYGGKSSA-N 0.000 title 1
229940073454 resiniferatoxin Drugs 0.000 title 1
208000011580 syndromic disease Diseases 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT98925862T 1997-06-10 1998-06-08 Verwendung einer zusammensetzung enthaltend capsaicin oder resiniferatoxin zur behandlung des reizdarmsyndroms ATE262892T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9711962.2A GB9711962D0 (en)	1997-06-10	1997-06-10	Therapeutically active compositions
PCT/GB1998/001673 WO1998056356A1 (en)	1997-06-10	1998-06-08	Therapeutically active compositions

Publications (1)

Publication Number	Publication Date
ATE262892T1 true ATE262892T1 (de)	2004-04-15

Family

ID=10813845

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98925862T ATE262892T1 (de)	1997-06-10	1998-06-08	Verwendung einer zusammensetzung enthaltend capsaicin oder resiniferatoxin zur behandlung des reizdarmsyndroms

Country Status (17)

Country	Link
US (1)	US6201014B1 (de)
EP (1)	EP0988028B1 (de)
JP (1)	JP2002513418A (de)
KR (1)	KR20010013618A (de)
CN (1)	CN1198594C (de)
AR (1)	AR012960A1 (de)
AT (1)	ATE262892T1 (de)
AU (1)	AU737606B2 (de)
BR (1)	BR9809994A (de)
CA (1)	CA2291796C (de)
DE (1)	DE69822822T2 (de)
GB (3)	GB9711962D0 (de)
HU (1)	HUP0004245A2 (de)
ID (1)	ID22878A (de)
PL (1)	PL337337A1 (de)
WO (1)	WO1998056356A1 (de)
ZA (1)	ZA984920B (de)

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US6802841B2 (en) *	1998-06-04	2004-10-12	Curon Medical, Inc.	Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction
GB9812426D0 (en) *	1998-06-10	1998-08-05	Reckitt & Colmann Prod Ltd	Improvements in or relating to organic compositions
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AU3582101A (en) *	2000-03-01	2001-09-12	Euro-Celtique S.A.	The treatment of functional gastrointestinal disorders
US6759064B2 (en)	2001-02-22	2004-07-06	Purdue Research Foundation	Compositions based on vanilloid-catechin synergies for prevention and treatment of cancer
US7192612B2 (en) *	2001-02-22	2007-03-20	Purdue Research Foundation	Compositions and methods based on synergies between capsicum extracts and tea catechins for prevention and treatment of cancer
US6428822B1 (en)	2001-04-03	2002-08-06	Chengzhi Life Science Company, Ltd.	Extracts of mixed arctium lappa L., carrot and whole radish for treating hypertension, constipation and detoxification
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US7198804B2 (en) *	2002-04-12	2007-04-03	Helixir Co., Ltd.	Crude drug composition for preventing and treating gastrointestinal dyskinetic diseases
MXPA05006670A (es)	2002-12-18	2005-10-19	Algorx Pharmaceuticals Inc	Administracion de capsaicinoides.
US20040161481A1 (en) *	2002-12-18	2004-08-19	Algorx	Administration of capsaicinoids
US20050085652A1 (en) *	2003-04-08	2005-04-21	Algorx Pharmaceuticals, Inc.	Preparation and purification of synthetic capsaicin
US20100159000A1 (en) *	2003-11-10	2010-06-24	Lundeen Sr James E	Medicine for treating gastrointestinal disorder including fecal incontinence
AT413646B (de) *	2004-04-02	2006-04-15	Hammer Johann Dr	Verwendung von capsaicin und/oder capsaicinoiden
US20050277657A1 (en) *	2004-06-15	2005-12-15	Dusan Ninkov	Method of protection of biologically active essential oils and pharmaceutical composition for weight control and enhance fat burning in adults, adolescents and children
AU2005309586A1 (en) *	2004-11-24	2006-06-01	Algorx Pharmaceuticals, Inc.	Capsaicinoid gel formulation and uses thereof
JP5775246B2 (ja)	2004-12-28	2015-09-09	メステックスアクチェンゲゼルシャフトＭｅｓｔｅｘＡｇ	関節痛を治療する薬剤を生成するためのレシニフェラトキシン（ｒｔｘ）の使用方法および前記薬剤を適用する方法
WO2008052183A2 (en)	2006-10-27	2008-05-02	Bmb Patent Holding Corporation	Therapeutic compositions and methods of treatment with capsianoside-type compounds
AU2008292907A1 (en) *	2007-08-29	2009-03-05	Sorbent Therapeutics, Inc.	Absorbent polymeric compositions with varying counterion content and their methods of preparation and use
KR20090047637A (ko) *	2007-11-08	2009-05-13	재단법인서울대학교산학협력재단	커큐민 또는 이의 약학적으로 허용가능한 염을유효성분으로 함유하는 통증 예방 및 치료용 조성물
HUP0700755A2 (en) *	2007-11-26	2009-08-28	Pannonpharma Gyogyszergyar	Pharmaceutical compositions containing capsaicionoid and non-steroidal anti-inflammatory drug
US8697155B2 (en) *	2008-07-22	2014-04-15	Mayo Foundation For Medical Education And Research	Treatment of obesity and related disorders
US20110200669A1 (en) *	2010-02-15	2011-08-18	Winston Laboratories, Inc.	Method and compositions of civamide to treat disease of the intestines
KR101378973B1 (ko) *	2012-04-13	2014-03-28	한미약품 주식회사	구형에 가까운 형태의 다중 투여 단위 정제를 포함하는 경질 캡슐 복합 제형 및 이의 제조방법
CN103027901B (zh) *	2012-12-11	2014-11-12	广东药学院	一种载辣椒素壳聚糖微球肠溶片及其制备方法
US10092528B2 (en)	2013-03-13	2018-10-09	Altria Client Services Llc	Application of encapsulated capsaicin and analogues thereof for controlling calorie intake
US9289418B2 (en)	2013-03-15	2016-03-22	Cedars-Sinai Medical Center	Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens
JP2016516717A (ja)	2013-03-15	2016-06-09	シーダーズ−サイナイメディカルセンター	メタン細菌に起因または関連する疾患および状態を診断、選択、および処置する方法
JP2017509596A (ja)	2014-01-30	2017-04-06	オムニアクティブヘルステクノロジーズリミテッド	辛味がある油性芳香性物質の組成物およびその調製方法
KR102425303B1 (ko)	2014-08-13	2022-07-25	세다르스-신나이 메디칼 센터	항-메탄생성 조성물 및 그것의 용도
WO2016161085A1 (en) *	2015-04-01	2016-10-06	Cedars-Sinai Medical Center	Anti-methanogenic lovastatin analogs or derivatives and uses thereof
WO2021011002A1 (en) *	2019-07-18	2021-01-21	Dignify Therapeutics, Llc	Compositions and methods for inducing defecation
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1997
- 1997-06-10 GB GBGB9711962.2A patent/GB9711962D0/en active Pending
1998
- 1998-06-03 GB GBGB9811819.3A patent/GB9811819D0/en active Pending
- 1998-06-08 WO PCT/GB1998/001673 patent/WO1998056356A1/en not_active Ceased
- 1998-06-08 CN CNB988060469A patent/CN1198594C/zh not_active Expired - Fee Related
- 1998-06-08 CA CA002291796A patent/CA2291796C/en not_active Expired - Fee Related
- 1998-06-08 DE DE1998622822 patent/DE69822822T2/de not_active Expired - Fee Related
- 1998-06-08 US US09/445,514 patent/US6201014B1/en not_active Expired - Fee Related
- 1998-06-08 ID IDW991447A patent/ID22878A/id unknown
- 1998-06-08 HU HU0004245A patent/HUP0004245A2/hu unknown
- 1998-06-08 AU AU77829/98A patent/AU737606B2/en not_active Ceased
- 1998-06-08 GB GB9827192A patent/GB2332147B/en not_active Expired - Fee Related
- 1998-06-08 AT AT98925862T patent/ATE262892T1/de not_active IP Right Cessation
- 1998-06-08 KR KR19997011628A patent/KR20010013618A/ko not_active Withdrawn
- 1998-06-08 PL PL98337337A patent/PL337337A1/xx not_active IP Right Cessation
- 1998-06-08 BR BR9809994-9A patent/BR9809994A/pt not_active Application Discontinuation
- 1998-06-08 JP JP50108699A patent/JP2002513418A/ja not_active Ceased
- 1998-06-08 EP EP98925862A patent/EP0988028B1/de not_active Expired - Lifetime
- 1998-06-10 AR ARP980102742A patent/AR012960A1/es not_active Application Discontinuation
- 1998-06-18 ZA ZA984920A patent/ZA984920B/xx unknown

Also Published As

Publication number	Publication date
US6201014B1 (en)	2001-03-13
ZA984920B (en)	1999-07-01
EP0988028B1 (de)	2004-03-31
PL337337A1 (en)	2000-08-14
GB2332147B (en)	1999-10-27
ID22878A (id)	1999-12-16
BR9809994A (pt)	2000-08-01
KR20010013618A (ko)	2001-02-26
GB2332147A (en)	1999-06-16
EP0988028A1 (de)	2000-03-29
DE69822822D1 (de)	2004-05-06
AU7782998A (en)	1998-12-30
CN1198594C (zh)	2005-04-27
GB9711962D0 (en)	1997-08-06
CA2291796C (en)	2008-03-25
CN1259863A (zh)	2000-07-12
WO1998056356A1 (en)	1998-12-17
GB9827192D0 (en)	1999-02-03
AU737606B2 (en)	2001-08-23
CA2291796A1 (en)	1998-12-17
GB9811819D0 (en)	1998-07-29
HUP0004245A2 (hu)	2001-08-28
AR012960A1 (es)	2000-11-22
DE69822822T2 (de)	2005-01-13
JP2002513418A (ja)	2002-05-08

Legal Events

Date	Code	Title	Description
2004-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE262892T1 (de)	2004-04-15	Verwendung einer zusammensetzung enthaltend capsaicin oder resiniferatoxin zur behandlung des reizdarmsyndroms
DE60114580D1 (de)	2005-12-08	Verwendung von cyanochinolinen zur behandlung oder inhibierung von dickdarmpolypen
DE69806579D1 (de)	2002-08-22	Anlage zur behandlung von nahrungsmitteln
DE69716525D1 (de)	2002-11-28	Handgelenkstütze zur Behandlung des Karpaltunnelsyndroms
FI964314A7 (fi)	1996-10-25	Substituoidut sulfonamidit selektiivisinä beta3-agonisteina diabeteksen ja liikalihavuuden hoitoon
EP0709090A3 (de)	1996-08-28	Zusammensetzungen zur Behandlung von resistenten Tumoren
DE69722635D1 (de)	2003-07-10	Behandlung von materialien zur verbesserung der behandlung von viskoelastische flüssigkeiten
DE69941566D1 (de)	2009-12-03	N-acetylhomotaurinate zur verwendung in der behandlung von hyperkinesie
DE50009504D1 (de)	2005-03-17	Verwendung von retigabin zur behandlung von neuropathischen schmerzen
DE60019158D1 (de)	2005-05-04	Neue oxabispidin-verbindungen zur behandlung von herzarrhythmien
ATE291427T1 (de)	2005-04-15	Verwendung von optisch reinem (+)-norcisapride für die behandlung des reizdarmsyndroms
DE69934877D1 (de)	2007-03-08	Biochanin-angereicherter extrakt zur behandlung von estrogenabhängigen erkrankungen
DE69603089D1 (de)	1999-08-05	Zusammensetzung zur behandlung von mauerwerk
DE69807962D1 (de)	2002-10-24	Verfahren zur Reinigung von rohem 1,1,1,3,3-Pentafluorpropan
DE69943089D1 (de)	2011-02-10	Methode zur behandlung von staphylokokkeninfektionen
DE50006142D1 (de)	2004-05-27	Verfahren zur thermischen Behandlung von mehlförmigen Rohmaterialien
DE69939723D1 (de)	2008-11-20	Verwendung von Intereferon Gamma zur Behandlung von Herzhypertrophie
PT102054A (pt)	1998-04-30	Composicao para o tratamento de sementes de arroz
DE69931487D1 (de)	2006-06-29	Verwendung von apomorphin zur behandlung der vorzeitigen ejakulation
NO20010464D0 (no)	2001-01-26	Fremgangsmåter og sammensetninger for behandling av gastroösofrageal-reflukssyndrom
PT853959E (pt)	2003-03-31	Composicao para o tratamento do amianto
DE69822526D1 (de)	2004-04-29	Verfahren zur Konservierung von wassergefüllten Materialien
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