ATE262921T1 - Somatostatin und somatostatin agoniste zur behandlung der insulinsunempfindlichkeit und syndrome x - Google Patents

Somatostatin und somatostatin agoniste zur behandlung der insulinsunempfindlichkeit und syndrome x

Info

Publication number
ATE262921T1
ATE262921T1 AT98928308T AT98928308T ATE262921T1 AT E262921 T1 ATE262921 T1 AT E262921T1 AT 98928308 T AT98928308 T AT 98928308T AT 98928308 T AT98928308 T AT 98928308T AT E262921 T1 ATE262921 T1 AT E262921T1
Authority
AT
Austria
Prior art keywords
somatostatin
agonits
syndromes
treatment
insulin sensitivity
Prior art date
Application number
AT98928308T
Other languages
English (en)
Inventor
Michael Anthony Cawthorne
Yong-Ling Liu
Matthew V Sennitt
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Application granted granted Critical
Publication of ATE262921T1 publication Critical patent/ATE262921T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT98928308T 1997-05-13 1998-05-13 Somatostatin und somatostatin agoniste zur behandlung der insulinsunempfindlichkeit und syndrome x ATE262921T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85494397A 1997-05-13 1997-05-13
PCT/EP1998/003000 WO1998051332A1 (en) 1997-05-13 1998-05-13 Somatostatin and somatostatin agonists for treating insulin insensitivity and syndrome x

Publications (1)

Publication Number Publication Date
ATE262921T1 true ATE262921T1 (de) 2004-04-15

Family

ID=25319948

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98928308T ATE262921T1 (de) 1997-05-13 1998-05-13 Somatostatin und somatostatin agoniste zur behandlung der insulinsunempfindlichkeit und syndrome x

Country Status (10)

Country Link
US (2) US7256174B2 (de)
EP (1) EP0980253B1 (de)
AT (1) ATE262921T1 (de)
AU (1) AU8019898A (de)
CA (1) CA2289499C (de)
DE (1) DE69822810T2 (de)
DK (1) DK0980253T3 (de)
ES (1) ES2216290T3 (de)
PT (1) PT980253E (de)
WO (1) WO1998051332A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2199355A1 (en) 1997-03-06 1998-09-06 Bob Bishop Multiple beam laser welding apparatus
HUP0202648A3 (en) * 1998-06-12 2003-02-28 Sod Conseils Rech Applic Imidazolyl derivatives, pharmaceutical compositions containing them and their use
US6150333A (en) * 1998-07-30 2000-11-21 Biomeasure, Inc. Methods of using a somatostatin analogue
IL140837A0 (en) * 1998-07-30 2002-02-10 Sod Conseils Rech Applic Method of using lanreotide, a somatostatin analogue
EP1291022A1 (de) * 1998-07-30 2003-03-12 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Anwendungsverfahren für lanreotid, ein somatostatin analogon
US6903074B1 (en) 1999-06-04 2005-06-07 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Neuromedin b and somatostatin receptor agonists
CN1367793A (zh) * 1999-06-04 2002-09-04 研究及应用科学协会股份有限公司 神经调节肽b和生长抑素受体拮抗剂
US6864234B1 (en) 1999-06-25 2005-03-08 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Somatostatin agonists
CN1367792A (zh) * 1999-06-25 2002-09-04 研究及应用科学协会股份有限公司 促生长素抑制素激动剂
AU2004294269A1 (en) * 2003-11-25 2005-06-16 Novartis Ag Biomarkers for the efficacy of somatostatin analogue treatment

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4291022A (en) 1975-03-11 1981-09-22 Sandoz Ltd. Organic compounds
US4133782A (en) 1976-06-07 1979-01-09 The Salk Institute For Biological Studies Somatostatin analogs with dissociated biological activities
US4190575A (en) 1977-12-27 1980-02-26 American Home Products Corporation Polypeptides related to somatostatin
DE2860734D1 (en) 1977-06-08 1981-09-03 Merck & Co Inc Somatostatin analogs, process for their preparation and pharmaceutical compositions containing them
US4211693A (en) 1977-09-20 1980-07-08 The Salk Institute For Biological Studies Peptides with para-substituted phenylalanine
LU78191A1 (de) 1977-09-28 1979-05-25 Ciba Geigy Ag Verfahren zur herstellung von neuen cyclopeptiden
CA1107273A (en) 1978-05-19 1981-08-18 Chester A. Meyers Somatostatin analogs having a substituted tryptophyl residue in position eight
JPS5819669B2 (ja) 1978-10-28 1983-04-19 白井松新薬株式会社 新規生理活性ペプチド化合物及びその製造法
US4215039A (en) 1979-02-15 1980-07-29 American Home Products Corporation Somatostatin analogues
US4190648A (en) 1979-03-13 1980-02-26 Merck & Co., Inc. Peptides having somatostatin activity
US4316890A (en) 1979-03-16 1982-02-23 Ciba-Geigy Corporation Peptides and processes for the manufacture thereof
US4209426A (en) 1979-05-29 1980-06-24 American Home Products Corporation Polypeptides related to somatostatin
US4328214A (en) 1979-07-04 1982-05-04 Ciba-Geigy Corporation Cyclopeptides and pharmaceutical preparations thereof and also processes for their manufacture
US4235886A (en) 1979-10-31 1980-11-25 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
US4310518A (en) 1979-10-31 1982-01-12 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
CY1327A (en) 1979-11-27 1986-06-27 Sandoz Ag Novel polypeptides,processes for their production,pharmaceutical compositions comprising said polypeptides and their use
US4369179A (en) 1979-12-14 1983-01-18 Ciba-Geigy Corporation Acylpeptides
DD155985A5 (de) 1979-12-21 1982-07-21 Ciba Geigy Ag Verfahren zur herstellung cyclischr octapeptide
US4282143A (en) 1980-06-13 1981-08-04 American Home Products Corporation Octapeptides lowering growth hormone
DK81082A (da) 1981-03-06 1982-09-07 Sandoz Ag Fremgangsmaade til fremstilling af polypeptider
US4360516A (en) 1981-04-13 1982-11-23 Merck & Co., Inc. Modified D-retro cyclic hexapeptide somatostatin analogs
DE3264693D1 (en) 1981-12-24 1985-08-14 Ciba Geigy Ag Cyclic octapeptides and pharmaceutical compositions thereof, and processes for their production and use
US4476415A (en) * 1982-08-20 1984-10-09 Johnson Service Company Feedback transducer
US4486415A (en) 1983-08-15 1984-12-04 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
US4485101A (en) 1983-10-11 1984-11-27 Administrators Of The Tulane Educational Fund Peptides
US4522813A (en) 1983-10-27 1985-06-11 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
US4684620A (en) 1984-09-04 1987-08-04 Gibson-Stephens Neuropharmaceuticals, Inc. Cyclic polypeptides having mu-receptor specificity
HUT42101A (en) 1985-01-07 1987-06-29 Sandoz Ag Process for preparing stomatostatine derivatives and pharmaceutical compositions containing such compounds
US4725577A (en) 1985-04-25 1988-02-16 Administrators Of The Tulane Educational Fund Biologically active lysine containing octapeptides
US4650787A (en) 1985-04-25 1987-03-17 Schally Andrew Victor Biologically active octapeptides
US4585755A (en) 1985-04-29 1986-04-29 Merck & Co., Inc. Cyclic and bridged cyclic somatostatin analogs useful as local anti-inflammatory agents
US4904642A (en) 1985-09-12 1990-02-27 The Administrators Of The Tulane Educational Fund Therapeutic somatostatin analogs
US4853371A (en) 1986-06-17 1989-08-01 The Administrators Of The Tulane Educational Fund Therapeutic somatostatin analogs
US4871717A (en) 1987-01-07 1989-10-03 Administrators Of The Tulane Educational Fund Peptides
NO893088L (no) * 1988-08-18 1990-02-19 Syntex Inc Fremgangsmaate for fremstilling av terapeutisk virksomme somatostatinlignende cykliske peptidforbindelser.
WO1991009056A1 (en) 1989-12-08 1991-06-27 The Administrators Of The Tulane Educational Fund Octapeptide analogs of somatostatin having threonine at the sixth position
US5583104A (en) 1993-12-06 1996-12-10 Mayo Foundation For Medical Research And Education Treatment of proliferation of bile duct epithelium
US5763200A (en) 1995-05-12 1998-06-09 Biomeasure, Incorporated Inhibition of amylin release
US5708135A (en) * 1995-09-29 1998-01-13 Biomeasure Incorporated Cyclic peptide analogs of somatostatin
US5686418A (en) 1996-04-08 1997-11-11 Biomeasure Incorporated Prolonging survival of transplanted pancreatic cells
AU4133997A (en) * 1996-09-12 1998-04-02 Yarom Cohen Pharmaceutical composition for the treatment of syndrome x of reaven

Also Published As

Publication number Publication date
CA2289499C (en) 2010-02-23
AU8019898A (en) 1998-12-08
US7256174B2 (en) 2007-08-14
US20040072734A1 (en) 2004-04-15
WO1998051332A1 (en) 1998-11-19
DK0980253T3 (da) 2004-07-05
EP0980253A1 (de) 2000-02-23
US20080020974A1 (en) 2008-01-24
PT980253E (pt) 2004-08-31
HK1026843A1 (en) 2000-12-29
ES2216290T3 (es) 2004-10-16
EP0980253B1 (de) 2004-03-31
DE69822810D1 (de) 2004-05-06
DE69822810T2 (de) 2005-02-03
CA2289499A1 (en) 1998-11-19

Similar Documents

Publication Publication Date Title
DE69132688D1 (de) Methode zur behandlung und vorbeugung von typ-1 diabetis durch orale verabreichung von insulin
DE4497905T1 (de) Pharmazeutische Zusammensetzung zur Prävention und Behandlung des Motion-Sickness-Syndroms
DE69230046D1 (de) 2-Bromomelatonin zur Behandlung von Schlafstörungen
UA26213C2 (uk) Засіб для профілактики та лікуваhhя остеопорозу та фармацевтичhа композиція hа їх осhові
FI954941A7 (fi) Glukagonintapaisia insuliinitrooppisia peptidianalogeja, koostumuksia ja käyttömenetelmiä
HUP0301101A3 (en) Novel heterocyclic compounds process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
DE69027865D1 (de) ZUSAMMENSETZUNGEN enthaltend omega Conotoxin Peptide Derivate und deren Verwendung ZUR BEHANDLUNG VON ISCHÄMIE-ARTIGEN NEURONALEN SCHÄDIGUNGEN
DE69631157D1 (de) Pharmazeutische Zubereitung zur Verwendung in der Behandlung von Diabetes
ATE253892T1 (de) Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen
ITRM910922A1 (it) Composizione farmaceutica anticefalalgica per somministrazione endonasale, procedimento per prepararla e suo impiego terapeutico
ATE295176T1 (de) Verfahren zur unterstützung der differentialdiagnostik und behandlung von autistischen syndromen
EP1117357A4 (de) Verfahren und vorrichtung für verbesserte verabreichung von pharmazeutischen aktiven stoffen
ATE387912T1 (de) Transepikutane darreichungsform zur behandlung des restless leg syndroms
EE9800234A (et) Ravimeetod ja farmatseutiline kompositsioon
FI972669L (fi) Peptidin p277 analogeja ja niitä sisältäviä farmaseuttisia koostumuksia diabeteksen hoitamiseksi ja diagnosoimiseksi
DE69822810D1 (de) Somatostatin und somatostatin agoniste zur behandlung der insulinsunempfindlichkeit und syndrome x
DK0969843T3 (da) Antitussive formuleringer indeholdende theobromin
SE9603725D0 (sv) New teatment
ATE302025T1 (de) Vorrichtungen zur behandlung und diagnose des restless leg syndroms
DE4495520T1 (de) Verfahren und pharmazeutische Zusammensetzung zum zielgerichten Anwenden von Wirkstoffen
DE69620691D1 (de) Therapeutisches Mittel zur Behandlung der Hypercholesterinämie
NO20021625L (no) Synergistiske kombinasjoner av en NK1 reseptor antagonist og en GABA strukturell analog
ATE230609T1 (de) Verfahren zur behandlung von entzündungen und zusammensetzungen dafür
DE69925578D1 (de) Pharmazeutische zusammenstellung zur vorbeugung und behandlung von mit zellkrankheiten des augenhintergrundes zusammenhängenden krankheiten
WO2002064160A3 (en) Pharmaceutical compositions which inhibit vascular proliferation and method of use thereof

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0980253

Country of ref document: EP

REN Ceased due to non-payment of the annual fee