DK0980253T3 - Somatostatin og somatostatinagonister til behandling af insulininsensitivitet og syndrom X - Google Patents
Somatostatin og somatostatinagonister til behandling af insulininsensitivitet og syndrom XInfo
- Publication number
- DK0980253T3 DK0980253T3 DK98928308T DK98928308T DK0980253T3 DK 0980253 T3 DK0980253 T3 DK 0980253T3 DK 98928308 T DK98928308 T DK 98928308T DK 98928308 T DK98928308 T DK 98928308T DK 0980253 T3 DK0980253 T3 DK 0980253T3
- Authority
- DK
- Denmark
- Prior art keywords
- somatostatin
- syndrome
- treatment
- insulin sensitivity
- agonists
- Prior art date
Links
- 102000005157 Somatostatin Human genes 0.000 title abstract 6
- 108010056088 Somatostatin Proteins 0.000 title abstract 6
- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 title abstract 6
- 229960000553 somatostatin Drugs 0.000 title abstract 6
- 239000000556 agonist Substances 0.000 title abstract 3
- 206010022489 Insulin Resistance Diseases 0.000 title abstract 2
- 208000011580 syndromic disease Diseases 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85494397A | 1997-05-13 | 1997-05-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0980253T3 true DK0980253T3 (da) | 2004-07-05 |
Family
ID=25319948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98928308T DK0980253T3 (da) | 1997-05-13 | 1998-05-13 | Somatostatin og somatostatinagonister til behandling af insulininsensitivitet og syndrom X |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7256174B2 (da) |
| EP (1) | EP0980253B1 (da) |
| AT (1) | ATE262921T1 (da) |
| AU (1) | AU8019898A (da) |
| CA (1) | CA2289499C (da) |
| DE (1) | DE69822810T2 (da) |
| DK (1) | DK0980253T3 (da) |
| ES (1) | ES2216290T3 (da) |
| PT (1) | PT980253E (da) |
| WO (1) | WO1998051332A1 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2199355A1 (en) | 1997-03-06 | 1998-09-06 | Bob Bishop | Multiple beam laser welding apparatus |
| HUP0202648A3 (en) * | 1998-06-12 | 2003-02-28 | Sod Conseils Rech Applic | Imidazolyl derivatives, pharmaceutical compositions containing them and their use |
| US6150333A (en) * | 1998-07-30 | 2000-11-21 | Biomeasure, Inc. | Methods of using a somatostatin analogue |
| IL140837A0 (en) * | 1998-07-30 | 2002-02-10 | Sod Conseils Rech Applic | Method of using lanreotide, a somatostatin analogue |
| EP1291022A1 (en) * | 1998-07-30 | 2003-03-12 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Methods of using lanreotide, a somatostatin analogue |
| US6903074B1 (en) | 1999-06-04 | 2005-06-07 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Neuromedin b and somatostatin receptor agonists |
| CN1367793A (zh) * | 1999-06-04 | 2002-09-04 | 研究及应用科学协会股份有限公司 | 神经调节肽b和生长抑素受体拮抗剂 |
| US6864234B1 (en) | 1999-06-25 | 2005-03-08 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Somatostatin agonists |
| CN1367792A (zh) * | 1999-06-25 | 2002-09-04 | 研究及应用科学协会股份有限公司 | 促生长素抑制素激动剂 |
| AU2004294269A1 (en) * | 2003-11-25 | 2005-06-16 | Novartis Ag | Biomarkers for the efficacy of somatostatin analogue treatment |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4291022A (en) | 1975-03-11 | 1981-09-22 | Sandoz Ltd. | Organic compounds |
| US4133782A (en) | 1976-06-07 | 1979-01-09 | The Salk Institute For Biological Studies | Somatostatin analogs with dissociated biological activities |
| US4190575A (en) | 1977-12-27 | 1980-02-26 | American Home Products Corporation | Polypeptides related to somatostatin |
| DE2860734D1 (en) | 1977-06-08 | 1981-09-03 | Merck & Co Inc | Somatostatin analogs, process for their preparation and pharmaceutical compositions containing them |
| US4211693A (en) | 1977-09-20 | 1980-07-08 | The Salk Institute For Biological Studies | Peptides with para-substituted phenylalanine |
| LU78191A1 (de) | 1977-09-28 | 1979-05-25 | Ciba Geigy Ag | Verfahren zur herstellung von neuen cyclopeptiden |
| CA1107273A (en) | 1978-05-19 | 1981-08-18 | Chester A. Meyers | Somatostatin analogs having a substituted tryptophyl residue in position eight |
| JPS5819669B2 (ja) | 1978-10-28 | 1983-04-19 | 白井松新薬株式会社 | 新規生理活性ペプチド化合物及びその製造法 |
| US4215039A (en) | 1979-02-15 | 1980-07-29 | American Home Products Corporation | Somatostatin analogues |
| US4190648A (en) | 1979-03-13 | 1980-02-26 | Merck & Co., Inc. | Peptides having somatostatin activity |
| US4316890A (en) | 1979-03-16 | 1982-02-23 | Ciba-Geigy Corporation | Peptides and processes for the manufacture thereof |
| US4209426A (en) | 1979-05-29 | 1980-06-24 | American Home Products Corporation | Polypeptides related to somatostatin |
| US4328214A (en) | 1979-07-04 | 1982-05-04 | Ciba-Geigy Corporation | Cyclopeptides and pharmaceutical preparations thereof and also processes for their manufacture |
| US4235886A (en) | 1979-10-31 | 1980-11-25 | Merck & Co., Inc. | Cyclic hexapeptide somatostatin analogs |
| US4310518A (en) | 1979-10-31 | 1982-01-12 | Merck & Co., Inc. | Cyclic hexapeptide somatostatin analogs |
| CY1327A (en) | 1979-11-27 | 1986-06-27 | Sandoz Ag | Novel polypeptides,processes for their production,pharmaceutical compositions comprising said polypeptides and their use |
| US4369179A (en) | 1979-12-14 | 1983-01-18 | Ciba-Geigy Corporation | Acylpeptides |
| DD155985A5 (de) | 1979-12-21 | 1982-07-21 | Ciba Geigy Ag | Verfahren zur herstellung cyclischr octapeptide |
| US4282143A (en) | 1980-06-13 | 1981-08-04 | American Home Products Corporation | Octapeptides lowering growth hormone |
| DK81082A (da) | 1981-03-06 | 1982-09-07 | Sandoz Ag | Fremgangsmaade til fremstilling af polypeptider |
| US4360516A (en) | 1981-04-13 | 1982-11-23 | Merck & Co., Inc. | Modified D-retro cyclic hexapeptide somatostatin analogs |
| DE3264693D1 (en) | 1981-12-24 | 1985-08-14 | Ciba Geigy Ag | Cyclic octapeptides and pharmaceutical compositions thereof, and processes for their production and use |
| US4476415A (en) * | 1982-08-20 | 1984-10-09 | Johnson Service Company | Feedback transducer |
| US4486415A (en) | 1983-08-15 | 1984-12-04 | Merck & Co., Inc. | Cyclic hexapeptide somatostatin analogs |
| US4485101A (en) | 1983-10-11 | 1984-11-27 | Administrators Of The Tulane Educational Fund | Peptides |
| US4522813A (en) | 1983-10-27 | 1985-06-11 | Merck & Co., Inc. | Cyclic hexapeptide somatostatin analogs |
| US4684620A (en) | 1984-09-04 | 1987-08-04 | Gibson-Stephens Neuropharmaceuticals, Inc. | Cyclic polypeptides having mu-receptor specificity |
| HUT42101A (en) | 1985-01-07 | 1987-06-29 | Sandoz Ag | Process for preparing stomatostatine derivatives and pharmaceutical compositions containing such compounds |
| US4725577A (en) | 1985-04-25 | 1988-02-16 | Administrators Of The Tulane Educational Fund | Biologically active lysine containing octapeptides |
| US4650787A (en) | 1985-04-25 | 1987-03-17 | Schally Andrew Victor | Biologically active octapeptides |
| US4585755A (en) | 1985-04-29 | 1986-04-29 | Merck & Co., Inc. | Cyclic and bridged cyclic somatostatin analogs useful as local anti-inflammatory agents |
| US4904642A (en) | 1985-09-12 | 1990-02-27 | The Administrators Of The Tulane Educational Fund | Therapeutic somatostatin analogs |
| US4853371A (en) | 1986-06-17 | 1989-08-01 | The Administrators Of The Tulane Educational Fund | Therapeutic somatostatin analogs |
| US4871717A (en) | 1987-01-07 | 1989-10-03 | Administrators Of The Tulane Educational Fund | Peptides |
| NO893088L (no) * | 1988-08-18 | 1990-02-19 | Syntex Inc | Fremgangsmaate for fremstilling av terapeutisk virksomme somatostatinlignende cykliske peptidforbindelser. |
| WO1991009056A1 (en) | 1989-12-08 | 1991-06-27 | The Administrators Of The Tulane Educational Fund | Octapeptide analogs of somatostatin having threonine at the sixth position |
| US5583104A (en) | 1993-12-06 | 1996-12-10 | Mayo Foundation For Medical Research And Education | Treatment of proliferation of bile duct epithelium |
| US5763200A (en) | 1995-05-12 | 1998-06-09 | Biomeasure, Incorporated | Inhibition of amylin release |
| US5708135A (en) * | 1995-09-29 | 1998-01-13 | Biomeasure Incorporated | Cyclic peptide analogs of somatostatin |
| US5686418A (en) | 1996-04-08 | 1997-11-11 | Biomeasure Incorporated | Prolonging survival of transplanted pancreatic cells |
| AU4133997A (en) * | 1996-09-12 | 1998-04-02 | Yarom Cohen | Pharmaceutical composition for the treatment of syndrome x of reaven |
-
1998
- 1998-05-13 PT PT98928308T patent/PT980253E/pt unknown
- 1998-05-13 WO PCT/EP1998/003000 patent/WO1998051332A1/en not_active Ceased
- 1998-05-13 ES ES98928308T patent/ES2216290T3/es not_active Expired - Lifetime
- 1998-05-13 AU AU80198/98A patent/AU8019898A/en not_active Abandoned
- 1998-05-13 AT AT98928308T patent/ATE262921T1/de not_active IP Right Cessation
- 1998-05-13 EP EP98928308A patent/EP0980253B1/en not_active Expired - Lifetime
- 1998-05-13 DE DE69822810T patent/DE69822810T2/de not_active Expired - Lifetime
- 1998-05-13 CA CA2289499A patent/CA2289499C/en not_active Expired - Fee Related
- 1998-05-13 DK DK98928308T patent/DK0980253T3/da active
-
2003
- 2003-02-18 US US10/369,143 patent/US7256174B2/en not_active Expired - Fee Related
-
2007
- 2007-08-02 US US11/833,035 patent/US20080020974A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2289499C (en) | 2010-02-23 |
| AU8019898A (en) | 1998-12-08 |
| US7256174B2 (en) | 2007-08-14 |
| US20040072734A1 (en) | 2004-04-15 |
| WO1998051332A1 (en) | 1998-11-19 |
| EP0980253A1 (en) | 2000-02-23 |
| US20080020974A1 (en) | 2008-01-24 |
| PT980253E (pt) | 2004-08-31 |
| HK1026843A1 (en) | 2000-12-29 |
| ATE262921T1 (de) | 2004-04-15 |
| ES2216290T3 (es) | 2004-10-16 |
| EP0980253B1 (en) | 2004-03-31 |
| DE69822810D1 (de) | 2004-05-06 |
| DE69822810T2 (de) | 2005-02-03 |
| CA2289499A1 (en) | 1998-11-19 |
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