ATE262926T1 - Asorbierbare mikropartikel - Google Patents

Asorbierbare mikropartikel

Info

Publication number
ATE262926T1
ATE262926T1 AT99903216T AT99903216T ATE262926T1 AT E262926 T1 ATE262926 T1 AT E262926T1 AT 99903216 T AT99903216 T AT 99903216T AT 99903216 T AT99903216 T AT 99903216T AT E262926 T1 ATE262926 T1 AT E262926T1
Authority
AT
Austria
Prior art keywords
asorbable
microparticles
asorbable microparticles
Prior art date
Application number
AT99903216T
Other languages
English (en)
Inventor
Shalaby Wahba Shalaby
Original Assignee
Poly Med Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poly Med Inc filed Critical Poly Med Inc
Application granted granted Critical
Publication of ATE262926T1 publication Critical patent/ATE262926T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6927Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585Ion exchange resins, e.g. polystyrene sulfonic acid resin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT99903216T 1998-01-29 1999-01-20 Asorbierbare mikropartikel ATE262926T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1539498A 1998-01-29 1998-01-29
PCT/US1999/001180 WO1999038536A1 (en) 1998-01-29 1999-01-20 Absorbable microparticles

Publications (1)

Publication Number Publication Date
ATE262926T1 true ATE262926T1 (de) 2004-04-15

Family

ID=21771154

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99903216T ATE262926T1 (de) 1998-01-29 1999-01-20 Asorbierbare mikropartikel

Country Status (19)

Country Link
US (1) US20060210641A1 (de)
EP (1) EP1053020B1 (de)
JP (2) JP3842042B2 (de)
CN (1) CN1289256A (de)
AR (1) AR014510A1 (de)
AT (1) ATE262926T1 (de)
AU (1) AU2329199A (de)
CA (1) CA2318152A1 (de)
DE (1) DE69916031T2 (de)
DK (1) DK1053020T3 (de)
ES (1) ES2217738T3 (de)
HU (1) HUP0101250A3 (de)
IL (2) IL137388A (de)
NO (1) NO20003810L (de)
PL (1) PL193111B1 (de)
PT (1) PT1053020E (de)
RU (1) RU2237471C2 (de)
TW (1) TWI255721B (de)
WO (1) WO1999038536A1 (de)

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US6756480B2 (en) 2000-04-27 2004-06-29 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
WO2002040537A2 (en) * 2000-11-16 2002-05-23 Novo Nordisk A/S Analogues and derivatives of gastrin releasing peptide (grp)
FR2825273B1 (fr) * 2001-05-29 2006-11-24 Oreal Composition pour le traitement des signes cutanes du vieillissement
EP2210900A3 (de) 2003-12-16 2010-08-11 Ipsen Pharma GlLP-1-Analoga
JP2007517912A (ja) * 2004-01-13 2007-07-05 バソジェニックス ファーマシューティカルズ, インコーポレイテッド 心脈管および腎臓の適応症のための制御放出cgrp送達組成物
US20090023643A1 (en) * 2004-01-13 2009-01-22 Vasogenix Pharmaceuticals, Inc. Methods For Treating Acute Myocardial Infarction By Administering Calcitonin Gene Related Peptide And Compositions Containing The Same
EP2118123B1 (de) 2007-01-31 2015-10-14 Dana-Farber Cancer Institute, Inc. Stabilisierte p53-peptide und deren verwendungen
EP2508531B1 (de) 2007-03-28 2016-10-19 President and Fellows of Harvard College Geheftete Polypeptide
US20100256056A1 (en) 2007-09-07 2010-10-07 Zheng Xin Dong Analogues of exendin-4 and exendin-3
MX2011000147A (es) 2008-07-04 2011-05-24 Traslational Cancer Drugs Pharma S L Metodos para el tratamiento y diagnostico del cancer.
WO2010016940A2 (en) 2008-08-07 2010-02-11 Ipsen Pharma S.A.S. Analogues of glucose-dependent insulinotropic polypeptide
AU2009280012B2 (en) 2008-08-07 2012-12-06 Ipsen Pharma S.A.S. Truncated analogues of glucose-dependent insulinotropic polypeptide
US8999940B2 (en) 2008-08-07 2015-04-07 Ipsen Pharma S.A.S. Analogues of glucose-dependent insulinotropic polypeptide (GIP) modified at N-terminal
ES2493618T3 (es) 2009-02-12 2014-09-12 Proyecto De Biomedicina Cima, S.L. Uso de la cardiotrofina-1 para el tratamiento de enfermedades metabólicas
CA2768621C (en) 2009-07-22 2016-04-05 Ipsen Pharma S.A.S. Analogues of insulin-like growth factor-1 (igf-1) having amino acid substitution at position 59
US9850296B2 (en) 2010-08-10 2017-12-26 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
EP2603520A4 (de) * 2010-08-10 2014-02-19 Ecole Polytech Erythrozytenbindende therapeutika
US9517257B2 (en) 2010-08-10 2016-12-13 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
MX355543B (es) 2010-08-13 2018-04-20 Aileron Therapeutics Inc Star Macrociclos peptidomiméticos.
EA018472B1 (ru) * 2010-09-15 2013-08-30 Открытое Акционерное Общество "Протек" Частицы, содержащие эритропоэтин, для лечения и профилактики неврологических и гематологических заболеваний и нарушений
CA2833676C (en) * 2011-06-14 2019-04-23 Ipsen Pharma S.A.S. A sustained-release composition containing peptides as active ingredient
MX358886B (es) 2011-10-18 2018-08-31 Aileron Therapeutics Inc Macrociclos peptidomimeticos.
EP3574897B1 (de) 2011-11-18 2022-01-05 Regeneron Pharmaceuticals, Inc. Retardformulierung umfassend polymerproteinmikropartikel zur verwendung im glaskörper des auges zur behandlung vaskulärer augenleiden
CN104144695A (zh) 2012-02-15 2014-11-12 爱勒让治疗公司 三唑交联的和硫醚交联的拟肽大环化合物
CN107216380A (zh) 2012-02-15 2017-09-29 爱勒让治疗公司 拟肽大环化合物
JP6526563B2 (ja) 2012-11-01 2019-06-05 エイルロン セラピューティクス,インコーポレイテッド 二置換アミノ酸ならびにその調製および使用の方法
US10946079B2 (en) 2014-02-21 2021-03-16 Ecole Polytechnique Federale De Lausanne Glycotargeting therapeutics
KR20160135214A (ko) 2014-02-21 2016-11-25 에꼴 뽈리떼끄닉 뻬데랄 드 로잔느 (으뻬에프엘) 글리코타겟팅 치료제
US10046056B2 (en) 2014-02-21 2018-08-14 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
US10953101B2 (en) 2014-02-21 2021-03-23 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
AU2015320549A1 (en) 2014-09-24 2017-04-13 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
KR20170129879A (ko) 2015-03-20 2017-11-27 에일러론 테라퓨틱스 인코포레이티드 펩티드모방 거대고리 및 이의 용도
EP3370694A1 (de) 2015-11-06 2018-09-12 Fraunhofer Gesellschaft zur Förderung der angewandten Forschung e.V. Zusammensetzung mit einem biokompatiblen und biologisch abbaubaren polymer, nanoträger und arzneimittel sowie verfahren zur herstellung und verwendung davon
EP3638296A1 (de) 2017-06-16 2020-04-22 The University Of Chicago Zusammensetzungen und verfahren zur herbeiführung einer immuntoleranz
KR20210010879A (ko) 2018-05-09 2021-01-28 더 유니버서티 오브 시카고 면역 관용 관여 조성물 및 방법
CN113281317B (zh) * 2021-05-14 2022-04-29 北京指真生物科技有限公司 一种含有花菁类化合物的编码微球及其制备方法和应用

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EP0230654B1 (de) * 1985-12-28 1992-03-18 Sumitomo Pharmaceuticals Company, Limited Arzneimittel mit verzögerter stossweiser Freisetzung
US4938763B1 (en) * 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
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CA2099376A1 (en) * 1991-01-03 1992-07-04 Henry E. Auer Stabilization of proteins by cationic biopolymers
JPH06511237A (ja) * 1991-07-24 1994-12-15 コ、トーマス サイ イーング 治療用組成物およびその製造方法
US5366756A (en) * 1992-06-15 1994-11-22 United States Surgical Corporation Method for treating bioabsorbable implant material
US5672659A (en) * 1993-01-06 1997-09-30 Kinerton Limited Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
JP2944419B2 (ja) * 1993-05-10 1999-09-06 ノバルティス アクチエンゲゼルシャフト 持続性遊離組成物中の薬理学的活性成分の安定
EP0712421A1 (de) * 1993-07-23 1996-05-22 Massachusetts Institute Of Technology Nanopartikel und mikropartikel aus nichtlinearen hydrophilen-hydrophoben multiblockcopolymeren
US5612052A (en) * 1995-04-13 1997-03-18 Poly-Med, Inc. Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof
US5795922A (en) * 1995-06-06 1998-08-18 Clemson University Bone cement composistion containing microencapsulated radiopacifier and method of making same
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Also Published As

Publication number Publication date
NO20003810L (no) 2000-09-13
EP1053020A1 (de) 2000-11-22
WO1999038536A1 (en) 1999-08-05
AR014510A1 (es) 2001-02-28
US20060210641A1 (en) 2006-09-21
JP3842042B2 (ja) 2006-11-08
DE69916031D1 (de) 2004-05-06
HUP0101250A3 (en) 2006-06-28
IL137388A0 (en) 2001-07-24
DE69916031T2 (de) 2005-02-17
HUP0101250A2 (hu) 2001-08-28
CA2318152A1 (en) 1999-08-05
TWI255721B (en) 2006-06-01
AU2329199A (en) 1999-08-16
EP1053020B1 (de) 2004-03-31
NO20003810D0 (no) 2000-07-25
JP2005047928A (ja) 2005-02-24
ES2217738T3 (es) 2004-11-01
PT1053020E (pt) 2004-06-30
PL342662A1 (en) 2001-07-02
PL193111B1 (pl) 2007-01-31
RU2237471C2 (ru) 2004-10-10
IL137388A (en) 2005-05-17
CN1289256A (zh) 2001-03-28
JP2002501908A (ja) 2002-01-22
DK1053020T3 (da) 2004-07-26

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