ATE264523T1 - Verfahren zur herstellung einer bio-informatik- datenbank - Google Patents

Verfahren zur herstellung einer bio-informatik- datenbank

Info

Publication number
ATE264523T1
ATE264523T1 AT98936012T AT98936012T ATE264523T1 AT E264523 T1 ATE264523 T1 AT E264523T1 AT 98936012 T AT98936012 T AT 98936012T AT 98936012 T AT98936012 T AT 98936012T AT E264523 T1 ATE264523 T1 AT E264523T1
Authority
AT
Austria
Prior art keywords
chips
database
bio
creating
model
Prior art date
Application number
AT98936012T
Other languages
English (en)
Inventor
David J Balaban
Arun Aggarwal
Original Assignee
Affymetrix Inc A Delaware Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affymetrix Inc A Delaware Corp filed Critical Affymetrix Inc A Delaware Corp
Application granted granted Critical
Publication of ATE264523T1 publication Critical patent/ATE264523T1/de

Links

Classifications

    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04M—TELEPHONIC COMMUNICATION
    • H04M1/00—Substation equipment, e.g. for use by subscribers
    • H04M1/006—Call diverting means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/30—Microarray design
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04M—TELEPHONIC COMMUNICATION
    • H04M1/00—Substation equipment, e.g. for use by subscribers
    • H04M1/72—Mobile telephones; Cordless telephones, i.e. devices for establishing wireless links to base stations without route selection
    • H04M1/724—User interfaces specially adapted for cordless or mobile telephones
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04M—TELEPHONIC COMMUNICATION
    • H04M2207/00—Type of exchange or network, i.e. telephonic medium, in which the telephonic communication takes place
    • H04M2207/20—Type of exchange or network, i.e. telephonic medium, in which the telephonic communication takes place hybrid systems
    • H04M2207/206—Type of exchange or network, i.e. telephonic medium, in which the telephonic communication takes place hybrid systems composed of PSTN and wireless network
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04M—TELEPHONIC COMMUNICATION
    • H04M3/00—Automatic or semi-automatic exchanges
    • H04M3/42—Systems providing special services or facilities to subscribers
    • H04M3/46—Arrangements for calling a number of substations in a predetermined sequence until an answer is obtained
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04M—TELEPHONIC COMMUNICATION
    • H04M3/00—Automatic or semi-automatic exchanges
    • H04M3/42—Systems providing special services or facilities to subscribers
    • H04M3/54—Arrangements for diverting calls for one subscriber to another predetermined subscriber
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/92—Computer assisted medical diagnostics
    • Y10S128/922—Computer assisted medical diagnostics including image analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S707/00—Data processing: database and file management or data structures
    • Y10S707/912—Applications of a database
    • Y10S707/923—Intellectual property
    • Y10S707/924—Patent procedure
    • Y10S707/925—Drafting an application
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S707/00—Data processing: database and file management or data structures
    • Y10S707/953—Organization of data
    • Y10S707/955—Object-oriented
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S707/00—Data processing: database and file management or data structures
    • Y10S707/99931—Database or file accessing
    • Y10S707/99933—Query processing, i.e. searching
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S707/00—Data processing: database and file management or data structures
    • Y10S707/99931—Database or file accessing
    • Y10S707/99933—Query processing, i.e. searching
    • Y10S707/99934—Query formulation, input preparation, or translation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S707/00—Data processing: database and file management or data structures
    • Y10S707/99941—Database schema or data structure
    • Y10S707/99944—Object-oriented database structure
    • Y10S707/99945—Object-oriented database structure processing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Molecular Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medical Informatics (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Signal Processing (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Bioethics (AREA)
  • Databases & Information Systems (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
AT98936012T 1997-07-25 1998-07-24 Verfahren zur herstellung einer bio-informatik- datenbank ATE264523T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US5384297P 1997-07-25 1997-07-25
US6943697P 1997-12-11 1997-12-11
US6919897P 1997-12-11 1997-12-11
PCT/US1998/015469 WO1999005591A2 (en) 1997-07-25 1998-07-24 Method and apparatus for providing a bioinformatics database

Publications (1)

Publication Number Publication Date
ATE264523T1 true ATE264523T1 (de) 2004-04-15

Family

ID=27368502

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98936012T ATE264523T1 (de) 1997-07-25 1998-07-24 Verfahren zur herstellung einer bio-informatik- datenbank

Country Status (6)

Country Link
US (10) US6484183B1 (de)
EP (4) EP1002264B1 (de)
JP (6) JP2001515234A (de)
AT (1) ATE264523T1 (de)
DE (1) DE69823206T2 (de)
WO (4) WO1999005591A2 (de)

Families Citing this family (339)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1223831A (en) 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
US5830655A (en) 1995-05-22 1998-11-03 Sri International Oligonucleotide sizing using cleavable primers
US5989835A (en) 1997-02-27 1999-11-23 Cellomics, Inc. System for cell-based screening
CA2270132A1 (en) 1996-11-06 1998-05-14 Sequenom, Inc. Dna diagnostics based on mass spectrometry
CA2274587A1 (en) 1996-12-10 1998-06-18 Genetrace Systems Inc. Releasable nonvolatile mass-label molecules
US7068830B2 (en) * 1997-07-25 2006-06-27 Affymetrix, Inc. Method and system for providing a probe array chip design database
US6484183B1 (en) * 1997-07-25 2002-11-19 Affymetrix, Inc. Method and system for providing a polymorphism database
US6826296B2 (en) * 1997-07-25 2004-11-30 Affymetrix, Inc. Method and system for providing a probe array chip design database
US6420108B2 (en) * 1998-02-09 2002-07-16 Affymetrix, Inc. Computer-aided display for comparative gene expression
US6990221B2 (en) * 1998-02-07 2006-01-24 Biodiscovery, Inc. Automated DNA array image segmentation and analysis
US6349144B1 (en) * 1998-02-07 2002-02-19 Biodiscovery, Inc. Automated DNA array segmentation and analysis
WO1999049403A1 (en) * 1998-03-26 1999-09-30 Incyte Pharmaceuticals, Inc. System and methods for analyzing biomolecular sequences
US6324479B1 (en) 1998-05-08 2001-11-27 Rosetta Impharmatics, Inc. Methods of determining protein activity levels using gene expression profiles
US6606622B1 (en) * 1998-07-13 2003-08-12 James M. Sorace Software method for the conversion, storage and querying of the data of cellular biological assays on the basis of experimental design
US20040199544A1 (en) * 2000-11-02 2004-10-07 Affymetrix, Inc. Method and apparatus for providing an expression data mining database
US6185561B1 (en) * 1998-09-17 2001-02-06 Affymetrix, Inc. Method and apparatus for providing and expression data mining database
IL142765A0 (en) 1998-11-13 2002-03-10 Cellomics Inc Methods and system for efficient collection and storage of experimental data
US6453241B1 (en) * 1998-12-23 2002-09-17 Rosetta Inpharmatics, Inc. Method and system for analyzing biological response signal data
US20040111219A1 (en) * 1999-02-22 2004-06-10 Sandeep Gulati Active interferometric signal analysis in software
US6136541A (en) 1999-02-22 2000-10-24 Vialogy Corporation Method and apparatus for analyzing hybridized biochip patterns using resonance interactions employing quantum expressor functions
US6142681A (en) 1999-02-22 2000-11-07 Vialogy Corporation Method and apparatus for interpreting hybridized bioelectronic DNA microarray patterns using self-scaling convergent reverberant dynamics
US6245511B1 (en) * 1999-02-22 2001-06-12 Vialogy Corp Method and apparatus for exponentially convergent therapy effectiveness monitoring using DNA microarray based viral load measurements
US6507788B1 (en) * 1999-02-25 2003-01-14 Société de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.) Rational selection of putative peptides from identified nucleotide, or peptide sequences, of unknown function
US6215894B1 (en) * 1999-02-26 2001-04-10 General Scanning, Incorporated Automatic imaging and analysis of microarray biochips
JP2000258368A (ja) * 1999-03-12 2000-09-22 Jeol Ltd サウンドモニタ機能を備えたｘ線マイクロアナライザ
DE60026190T2 (de) * 1999-03-30 2006-08-31 Fuji Photo Film Co., Ltd., Minami-Ashigara Verfahren und Vorrichtung zur selektiven Anzeige von Ergebnissen und übereinstimmenden Bildern
US6446072B1 (en) * 1999-04-13 2002-09-03 Michael D. Schulze Method of obtaining an electronically-stored financial document
US20030228565A1 (en) * 2000-04-26 2003-12-11 Cytokinetics, Inc. Method and apparatus for predictive cellular bioinformatics
US6743576B1 (en) 1999-05-14 2004-06-01 Cytokinetics, Inc. Database system for predictive cellular bioinformatics
US6876760B1 (en) 2000-12-04 2005-04-05 Cytokinetics, Inc. Classifying cells based on information contained in cell images
US6651008B1 (en) 1999-05-14 2003-11-18 Cytokinetics, Inc. Database system including computer code for predictive cellular bioinformatics
US7151847B2 (en) 2001-02-20 2006-12-19 Cytokinetics, Inc. Image analysis of the golgi complex
US6334099B1 (en) 1999-05-25 2001-12-25 Digital Gene Technologies, Inc. Methods for normalization of experimental data
JP3469504B2 (ja) * 1999-06-01 2003-11-25 日立ソフトウエアエンジニアリング株式会社 マイクロアレイチップ及びそのインデックス方法
WO2000077257A1 (en) * 1999-06-11 2000-12-21 Clingenix, Inc. Gene specific arrays and the use thereof
US6716579B1 (en) 1999-06-11 2004-04-06 Narayan Baidya Gene specific arrays, preparation and use
US7058517B1 (en) 1999-06-25 2006-06-06 Genaissance Pharmaceuticals, Inc. Methods for obtaining and using haplotype data
US6931396B1 (en) 1999-06-29 2005-08-16 Gene Logic Inc. Biological data processing
US6631211B1 (en) * 1999-07-08 2003-10-07 Perkinelmer Las, Inc. Interactive system for analyzing scatter plots
US6713309B1 (en) 1999-07-30 2004-03-30 Large Scale Proteomics Corporation Microarrays and their manufacture
US7179638B2 (en) 1999-07-30 2007-02-20 Large Scale Biology Corporation Microarrays and their manufacture by slicing
WO2001013105A1 (en) * 1999-07-30 2001-02-22 Agy Therapeutics, Inc. Techniques for facilitating identification of candidate genes
US7062076B1 (en) 1999-08-27 2006-06-13 Iris Biotechnologies, Inc. Artificial intelligence system for genetic analysis
EP2899660A1 (de) * 1999-08-27 2015-07-29 Iris Biotechnologies Inc. System mit künstlicher Intelligenz zur genetischen Analyse
CA2382436C (en) 1999-08-30 2011-05-17 Illumina, Inc. Methods for improving signal detection from an array
US7099502B2 (en) * 1999-10-12 2006-08-29 Biodiscovery, Inc. System and method for automatically processing microarrays
US7332275B2 (en) 1999-10-13 2008-02-19 Sequenom, Inc. Methods for detecting methylated nucleotides
AU776811C (en) 1999-10-13 2005-07-28 Agena Bioscience, Inc. Methods for generating databases and databases for identifying polymorphic genetic markers
WO2001031333A1 (en) * 1999-10-26 2001-05-03 Genometrix Genomics Incorporated Process for requesting biological experiments and for the delivery of experimental information
ATE391789T1 (de) 1999-12-10 2008-04-15 Invitrogen Corp Verwendung einer vielzahl von rekombinationsstellen mit einzigartiger spezifität beim rekombinatorischen klonen
CA2396495A1 (en) 2000-01-25 2001-08-02 Cellomics, Inc. Method and system for automated inference creation of physico-chemical interaction knowledge from databases of co-occurrence data
US20030097222A1 (en) * 2000-01-25 2003-05-22 Craford David M. Method, system, and computer software for providing a genomic web portal
EP1252513A4 (de) * 2000-01-25 2007-07-18 Affymetrix Inc Verfahren, system und software, um ein genomisches netzportal bereitzustellen
US20050214825A1 (en) * 2000-02-07 2005-09-29 John Stuelpnagel Multiplex sample analysis on universal arrays
US7582420B2 (en) * 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
US7955794B2 (en) * 2000-09-21 2011-06-07 Illumina, Inc. Multiplex nucleic acid reactions
US8076063B2 (en) 2000-02-07 2011-12-13 Illumina, Inc. Multiplexed methylation detection methods
US6770441B2 (en) * 2000-02-10 2004-08-03 Illumina, Inc. Array compositions and methods of making same
WO2001073119A2 (en) 2000-03-29 2001-10-04 Cambia Methods for genotyping by hybridization analysis
DE10015816A1 (de) * 2000-03-30 2001-10-18 Infineon Technologies Ag Biosensorchip
WO2001074405A1 (en) * 2000-03-31 2001-10-11 Gene Logic, Inc. Gene expression profiles in esophageal tissue
EP1312026A2 (de) * 2000-04-18 2003-05-21 Combimatrix Corporation Automatisiertes system und verfahren zur entwurf und analyse von angepassten biologischen arrays
US20030009295A1 (en) * 2001-03-14 2003-01-09 Victor Markowitz System and method for retrieving and using gene expression data from multiple sources
US20030171876A1 (en) * 2002-03-05 2003-09-11 Victor Markowitz System and method for managing gene expression data
US7020561B1 (en) 2000-05-23 2006-03-28 Gene Logic, Inc. Methods and systems for efficient comparison, identification, processing, and importing of gene expression data
US7577683B2 (en) * 2000-06-08 2009-08-18 Ingenuity Systems, Inc. Methods for the construction and maintenance of a knowledge representation system
US6741986B2 (en) * 2000-12-08 2004-05-25 Ingenuity Systems, Inc. Method and system for performing information extraction and quality control for a knowledgebase
US6772160B2 (en) * 2000-06-08 2004-08-03 Ingenuity Systems, Inc. Techniques for facilitating information acquisition and storage
US6931326B1 (en) 2000-06-26 2005-08-16 Genaissance Pharmaceuticals, Inc. Methods for obtaining and using haplotype data
US20020152196A1 (en) * 2000-07-07 2002-10-17 Westbrook Carol A. cDNA database and biochip for analysis of hematopoietic tissue
JP3517644B2 (ja) * 2000-07-13 2004-04-12 孝 五條堀 生命体の発現現象表示方法およびシステム並びにプログラム
US20020059326A1 (en) * 2000-07-25 2002-05-16 Derek Bernhart System, method, and computer program product for management of biological experiment information
NL1016034C2 (nl) 2000-08-03 2002-02-08 Tno Werkwijze en systeem voor het identificeren en kwantificeren van chemische componenten van een te onderzoeken mengsel van materialen.
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
EP2390819A1 (de) 2000-08-22 2011-11-30 Affymetrix, Inc. System, Verfahren und Computersoftwareprodukt zur Steuerung eines biologischen Microarray-Scanners
US7062092B2 (en) 2000-08-22 2006-06-13 Affymetrix, Inc. System, method, and computer software product for gain adjustment in biological microarray scanner
AU2001290545A1 (en) * 2000-08-22 2002-03-04 Varro Technologies, Inc. Method and system for sharing biological information
GB0021286D0 (en) * 2000-08-30 2000-10-18 Gemini Genomics Ab Identification of drug metabolic capacity
US6539102B1 (en) * 2000-09-01 2003-03-25 Large Scale Proteomics Reference database
US6813615B1 (en) 2000-09-06 2004-11-02 Cellomics, Inc. Method and system for interpreting and validating experimental data with automated reasoning
WO2002023308A2 (en) * 2000-09-12 2002-03-21 Viaken Systems, Inc. Techniques for providing and obtaining research and development information technology on remote computing resources
WO2002034944A1 (en) * 2000-10-23 2002-05-02 Dia Chip Limited High precision and intellectual biochip arrayer having function of respotting
US7117095B2 (en) * 2000-11-21 2006-10-03 Affymetrix, Inc. Methods for selecting nucleic acid probes
US8255791B2 (en) 2000-11-29 2012-08-28 Dov Koren Collaborative, flexible, interactive real-time displays
US7218764B2 (en) 2000-12-04 2007-05-15 Cytokinetics, Inc. Ploidy classification method
US6706867B1 (en) * 2000-12-19 2004-03-16 The United States Of America As Represented By The Department Of Health And Human Services DNA array sequence selection
US20020143768A1 (en) * 2000-12-21 2002-10-03 Berno Anthony Berno Probe array data storage and retrieval
WO2002059560A2 (en) * 2001-01-23 2002-08-01 Gene Logic, Inc. A method and system for predicting the biological activity, including toxicology and toxicity, of substances
US20020183936A1 (en) * 2001-01-24 2002-12-05 Affymetrix, Inc. Method, system, and computer software for providing a genomic web portal
WO2002059271A2 (en) * 2001-01-25 2002-08-01 Gene Logic, Inc. Gene expression profiles in breast tissue
US6949638B2 (en) * 2001-01-29 2005-09-27 Affymetrix, Inc. Photolithographic method and system for efficient mask usage in manufacturing DNA arrays
US20030017455A1 (en) * 2001-01-29 2003-01-23 Webb Peter G. Chemical array fabrication with identity map
US7315784B2 (en) * 2001-02-15 2008-01-01 Siemens Aktiengesellschaft Network for evaluating data obtained in a biochip measurement device
US6956961B2 (en) 2001-02-20 2005-10-18 Cytokinetics, Inc. Extracting shape information contained in cell images
US7016787B2 (en) 2001-02-20 2006-03-21 Cytokinetics, Inc. Characterizing biological stimuli by response curves
JP3867046B2 (ja) * 2001-02-23 2007-01-10 株式会社日立製作所 分析システム
US7110885B2 (en) 2001-03-08 2006-09-19 Dnaprint Genomics, Inc. Efficient methods and apparatus for high-throughput processing of gene sequence data
US6804679B2 (en) * 2001-03-12 2004-10-12 Affymetrix, Inc. System, method, and user interfaces for managing genomic data
US20020168651A1 (en) * 2001-03-12 2002-11-14 Affymetrix, Inc. Method and computer software product for determining orientation of sequence clusters
JP2002269114A (ja) * 2001-03-14 2002-09-20 Kousaku Ookubo 知識データベース及び知識データベースの構築方法
US20040033502A1 (en) * 2001-03-28 2004-02-19 Amanda Williams Gene expression profiles in esophageal tissue
JP2002297617A (ja) * 2001-03-29 2002-10-11 Hitachi Software Eng Co Ltd 生体高分子とプローブの相関関係表示方法
US7251568B2 (en) 2001-04-18 2007-07-31 Wyeth Methods and compositions for regulating bone and cartilage formation
WO2002085285A2 (en) * 2001-04-18 2002-10-31 Wyeth Methods and reagents for regulating bone and cartilage formation
US7155453B2 (en) * 2002-05-22 2006-12-26 Agilent Technologies, Inc. Biotechnology information naming system
US20070015146A1 (en) * 2001-05-22 2007-01-18 Gene Logic, Inc. Molecular nephrotoxicology modeling
CA2447357A1 (en) * 2001-05-22 2002-11-28 Gene Logic, Inc. Molecular toxicology modeling
US20030009294A1 (en) * 2001-06-07 2003-01-09 Jill Cheng Integrated system for gene expression analysis
AU2002316267A1 (en) * 2001-06-14 2003-01-02 Rigel Pharmaceuticals, Inc. Multidimensional biodata integration and relationship inference
WO2003001335A2 (en) * 2001-06-22 2003-01-03 Gene Logic, Inc. Platform for management and mining of genomic data
KR100794698B1 (ko) * 2001-06-28 2008-01-14 (주)바이오니아 생화학 물질 미세 배열 칩의 품질 검사 방법
WO2003005628A2 (en) * 2001-07-06 2003-01-16 Lipomics Technologies, Inc. Generating, viewing, interpreting, and utilizing a quantitative database of metabolites
US7447594B2 (en) * 2001-07-10 2008-11-04 Ocimum Biosolutions, Inc. Molecular cardiotoxicology modeling
WO2003068908A2 (en) * 2001-07-10 2003-08-21 Gene Logic, Inc. Cardiotoxin molecular toxicology modeling
JPWO2003027673A1 (ja) * 2001-07-31 2005-01-13 オリンパス株式会社 遺伝子検査装置およびそれを用いた標的核酸検出方法
US7251642B1 (en) 2001-08-06 2007-07-31 Gene Logic Inc. Analysis engine and work space manager for use with gene expression data
JP3977038B2 (ja) * 2001-08-27 2007-09-19 株式会社半導体エネルギー研究所 レーザ照射装置およびレーザ照射方法
US20030096248A1 (en) * 2001-09-04 2003-05-22 Vitivity, Inc. Diagnosis and treatment of vascular disease
EP1438420B1 (de) * 2001-09-24 2009-09-16 Lipomics Technologies, Inc. Verfahren zur verwendung von quantitativen lipidmetabolondaten
JP2003099624A (ja) * 2001-09-25 2003-04-04 Toyo Kohan Co Ltd Ｄｎａ提供システム
US20030087289A1 (en) * 2001-10-12 2003-05-08 Harry Zuzan Image analysis of high-density synthetic DNA microarrays
US6993173B2 (en) * 2001-10-12 2006-01-31 Duke University Methods for estimating probe cell locations in high-density synthetic DNA microarrays
US20060141493A1 (en) * 2001-11-09 2006-06-29 Duke University Office Of Science And Technology Atherosclerotic phenotype determinative genes and methods for using the same
EP1471405A4 (de) * 2001-11-12 2010-01-13 Gerite Associates Ltd Verfahren und einrichtung zum schutz von informationen vor unautorisierter benutzung
KR100474840B1 (ko) * 2001-11-15 2005-03-08 삼성전자주식회사 디렉토리를 이용한 유전자 분석용 마이크로어레이 탐침설계 방법 및 시스템
WO2003053586A1 (en) * 2001-12-19 2003-07-03 Affymetrix, Inc. Array plates and method for constructing array plates
US7225183B2 (en) * 2002-01-28 2007-05-29 Ipxl, Inc. Ontology-based information management system and method
US20030177143A1 (en) * 2002-01-28 2003-09-18 Steve Gardner Modular bioinformatics platform
US9418204B2 (en) * 2002-01-28 2016-08-16 Samsung Electronics Co., Ltd Bioinformatics system architecture with data and process integration
CA2474754C (en) 2002-02-04 2022-03-22 Ingenuity Systems, Inc. Systems for evaluating genomics data
US8793073B2 (en) 2002-02-04 2014-07-29 Ingenuity Systems, Inc. Drug discovery methods
US20030162183A1 (en) * 2002-02-27 2003-08-28 Robert Kincaid Array design system and method
US8722331B2 (en) * 2002-03-28 2014-05-13 University Of Toledo Method for selecting a treatment for non-small cell lung cancer using gene expression profiles
WO2003091391A2 (en) * 2002-04-23 2003-11-06 Duke University Atherosclerotic phenotype determinative genes and methods for using the same
EP1502098B1 (de) * 2002-05-03 2008-09-17 ViaLogy, LLC Verfahren zur charakterisierung der ausgangssignale eines microarrays
CA2484676A1 (en) 2002-05-03 2003-11-13 Sequenom, Inc. Kinase anchor protein muteins, peptides thereof, and related methods
US20030220844A1 (en) * 2002-05-24 2003-11-27 Marnellos Georgios E. Method and system for purchasing genetic data
US6763308B2 (en) 2002-05-28 2004-07-13 Sas Institute Inc. Statistical outlier detection for gene expression microarray data
US20030229848A1 (en) * 2002-06-05 2003-12-11 Udo Arend Table filtering in a computer user interface
US7504215B2 (en) 2002-07-12 2009-03-17 Affymetrix, Inc. Nucleic acid labeling methods
US20050216459A1 (en) * 2002-08-08 2005-09-29 Aditya Vailaya Methods and systems, for ontological integration of disparate biological data
US20050112689A1 (en) * 2003-04-04 2005-05-26 Robert Kincaid Systems and methods for statistically analyzing apparent CGH data anomalies and plotting same
US7941542B2 (en) * 2002-09-06 2011-05-10 Oracle International Corporation Methods and apparatus for maintaining application execution over an intermittent network connection
US7512496B2 (en) * 2002-09-25 2009-03-31 Soheil Shams Apparatus, method, and computer program product for determining confidence measures and combined confidence measures for assessing the quality of microarrays
CA2500936C (en) 2002-09-30 2012-10-30 Nimblegen Systems, Inc. Parallel loading of arrays
WO2004031351A2 (en) * 2002-10-01 2004-04-15 Nimblegen Systems, Inc. Microarrays having multiple oligonucleotides in single array features
US20040259105A1 (en) * 2002-10-03 2004-12-23 Jian-Bing Fan Multiplex nucleic acid analysis using archived or fixed samples
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
CA2505514A1 (en) * 2002-11-06 2004-05-27 Mount Sinai School Of Medicine Treatment of amyotrophic lateral sclerosis with nimesulide
EP2112229A3 (de) 2002-11-25 2009-12-02 Sequenom, Inc. Verfahren zum Identifizieren des Brustkrebsrisikos und zugehörige Behandlungen
WO2004050840A2 (en) * 2002-11-27 2004-06-17 The Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Integration of gene expression data and non-gene data
JP2004191160A (ja) * 2002-12-11 2004-07-08 Yokogawa Electric Corp バイオチップの測定方法および測定装置
KR100506089B1 (ko) * 2003-02-05 2005-08-05 삼성전자주식회사 이형 유전정보를 이용한 프로브 어레이 설계 시스템 및 방법
US7825929B2 (en) * 2003-04-04 2010-11-02 Agilent Technologies, Inc. Systems, tools and methods for focus and context viewing of large collections of graphs
US7750908B2 (en) * 2003-04-04 2010-07-06 Agilent Technologies, Inc. Focus plus context viewing and manipulation of large collections of graphs
WO2004090100A2 (en) * 2003-04-04 2004-10-21 Agilent Technologies, Inc. Visualizing expression data on chromosomal graphic schemes
CA2523875A1 (en) * 2003-04-28 2004-11-11 Public Health Agency Of Canada Sars virus nucleotide and amino acid sequences and uses thereof
US20040249791A1 (en) * 2003-06-03 2004-12-09 Waters Michael D. Method and system for developing and querying a sequence driven contextual knowledge base
EP2316973A1 (de) 2003-06-10 2011-05-04 The Trustees Of Boston University Nachweismethoden für Lungenerkrankungen
WO2005003301A2 (en) * 2003-06-17 2005-01-13 Signal Pharmaceuticals, Inc. Methods, compositions, and kits for predicting the effect of compounds on hot flash symptoms
US7235353B2 (en) 2003-07-18 2007-06-26 Cytokinetics, Inc. Predicting hepatotoxicity using cell based assays
US20050014217A1 (en) 2003-07-18 2005-01-20 Cytokinetics, Inc. Predicting hepatotoxicity using cell based assays
GB2423988A (en) 2003-07-18 2006-09-13 Cytokinetics Inc Characterizing biological stimuli by response curves
US7353116B2 (en) * 2003-07-31 2008-04-01 Agilent Technologies, Inc. Chemical array with test dependent signal reading or processing
US20050026154A1 (en) * 2003-07-31 2005-02-03 Laurakay Bruhn Masking chemical arrays
US20050026306A1 (en) * 2003-07-31 2005-02-03 Robert Kincaid Method and system for generating virtual-microarrays
US7475087B1 (en) 2003-08-29 2009-01-06 The United States Of America As Represented By The Secretary Of Agriculture Computer display tool for visualizing relationships between and among data
US20050049796A1 (en) * 2003-09-03 2005-03-03 Webb Peter G. Methods for encoding non-biological information on microarrays
US20050048506A1 (en) * 2003-09-03 2005-03-03 Fredrick Joseph P. Methods for encoding non-biological information on microarrays
WO2005024068A2 (en) 2003-09-05 2005-03-17 Sequenom, Inc. Allele-specific sequence variation analysis
DE602004027538D1 (de) 2003-12-01 2010-07-15 Life Technologies Corp Rekombinationsstellen enthaltende nukleinsäuremoleküle und verfahren zur verwendung davon
US20050191682A1 (en) 2004-02-17 2005-09-01 Affymetrix, Inc. Methods for fragmenting DNA
US7660709B2 (en) * 2004-03-18 2010-02-09 Van Andel Research Institute Bioinformatics research and analysis system and methods associated therewith
US7608394B2 (en) 2004-03-26 2009-10-27 Sequenom, Inc. Methods and compositions for phenotype identification based on nucleic acid methylation
EP1727911B1 (de) 2004-03-26 2013-01-23 Sequenom, Inc. Basenspezifische spaltung methylierungsspezifischer amplifikationsprodukte in kombination mit massenanalyse
KR100632973B1 (ko) * 2004-04-29 2006-10-12 주식회사 메딘텔 순환 짝짓기 시스템 및 순환 짝짓기 방법
US20060003335A1 (en) * 2004-06-30 2006-01-05 Crispino John D Methods for diagnosing acute megakaryoblastic leukemia
US7323318B2 (en) 2004-07-15 2008-01-29 Cytokinetics, Inc. Assay for distinguishing live and dead cells
US20080199480A1 (en) * 2004-07-22 2008-08-21 Sequenom, Inc. Methods for Identifying Risk of Type II Diabetes and Treatments Thereof
CN101031655A (zh) 2004-07-26 2007-09-05 陶氏环球技术公司 通过株工程改进蛋白表达的方法
EP1792263A2 (de) * 2004-09-02 2007-06-06 Vialogy Corporation Erkennung von interessensereignissen unter verwendung von quantenresonanzinterferometrie
EP1647600A3 (de) 2004-09-17 2006-06-28 Affymetrix, Inc. (A US Entity) Verfahren zur Kennzeichnung von biologischen Proben durch Hinzufügung von Nukleinsäre "bar-code" Markierungen
US20060073511A1 (en) 2004-10-05 2006-04-06 Affymetrix, Inc. Methods for amplifying and analyzing nucleic acids
US20060083609A1 (en) * 2004-10-14 2006-04-20 Augspurger Murray D Fluid cooled marine turbine housing
CA2524964A1 (en) 2004-10-29 2006-04-29 Affymetrix, Inc. Automated method of manufacturing polymer arrays
US7682782B2 (en) 2004-10-29 2010-03-23 Affymetrix, Inc. System, method, and product for multiple wavelength detection using single source excitation
US20090068650A1 (en) * 2005-02-11 2009-03-12 Southern Illinois University Metabolic Primers for the Detection of (Per) Chlorate-Reducing Bacteria and Methods of Use Thereof
US20060211004A1 (en) 2005-02-15 2006-09-21 Ilsley Diane D Methods and compositions for determining non-specific cytotoxicity of a transfection agent
US20090203547A1 (en) * 2005-02-18 2009-08-13 Albert Banes Gene and Cognate Protein Profiles and Methods to Determine Connective Tissue Markers in Normal and Pathologic Conditions
EP1856298B1 (de) 2005-02-18 2017-09-27 Monogram BioSciences, Inc. Verfahren und zusammensetzungen zur bestimmung der suszeptibilität für anti-hiv-mittel und des hiv-replikationsvermögens
US8178291B2 (en) 2005-02-18 2012-05-15 Monogram Biosciences, Inc. Methods and compositions for determining hypersusceptibility of HIV-1 to non-nucleoside reverse transcriptase inhibitors
US20070118295A1 (en) * 2005-03-02 2007-05-24 Al-Murrani Samer Waleed Khedhe Methods and Systems for Designing Animal Food Compositions
US20060286569A1 (en) * 2005-03-10 2006-12-21 Bar-Or Yuval A Method, apparatus, and system for authentication using labels containing nucleotide sequences
EP2604703B1 (de) 2005-03-14 2017-02-01 The Board of Trustees of the Leland Stanford Junior University Verfahren zur Bewertung der Haltbarkeit eines Pfropfs im Körper eines Empfängers fester Organtransplantate
JP2008537120A (ja) 2005-04-14 2008-09-11 ザ トラスティーズ オブ ボストン ユニバーシティ 分類予測を使用した肺障害についての診断
US20070026426A1 (en) * 2005-04-26 2007-02-01 Applera Corporation System for genetic surveillance and analysis
EP2458019A3 (de) 2005-05-27 2012-07-25 Monogram BioSciences, Inc. Verfahren und Zusammensetzungen zum Bestimmen der HIV-1-Beständigkeit gegenüber Proteasehemmern
WO2006133267A2 (en) 2005-06-06 2006-12-14 Monogram Biosciences, Inc. Methods and compositions for determining altered susceptibility of hiv-1 to anti-hiv drugs
WO2006133266A2 (en) * 2005-06-06 2006-12-14 Monogram Biosciences, Inc. Methods for determining resistance or susceptibility to hiv entry inhibitors
US8159959B2 (en) * 2005-11-07 2012-04-17 Vudu, Inc. Graphic user interface for playing video data
US7634363B2 (en) 2005-12-07 2009-12-15 Affymetrix, Inc. Methods for high throughput genotyping
EP1969506A1 (de) * 2005-12-13 2008-09-17 Erasmus University Medical Center Rotterdam Genetische hirntumor-markierer
US7646450B2 (en) * 2005-12-29 2010-01-12 Lg Display Co., Ltd. Light emitting diode array, method of manufacturing the same, backlight assembly having the same, and LCD having the same
US20070198729A1 (en) * 2006-02-07 2007-08-23 Yechuri Sitaramarao S SQL network gadget
JP2009529329A (ja) 2006-03-09 2009-08-20 トラスティーズ オブ ボストン ユニバーシティ 鼻腔上皮細胞の遺伝子発現プロファイルを用いた、肺疾患のための診断および予後診断の方法
WO2007139402A2 (en) * 2006-05-30 2007-12-06 Synergenz Bioscience Limited Methods and compositions for assessment of pulmonary function and disorders
EP3260556B1 (de) 2006-05-31 2019-07-31 Sequenom, Inc. Verfahren zur nukleinsäureextraktion aus einer probe
US8153369B2 (en) 2006-06-05 2012-04-10 Cancer Care Ontario Assessment of risk for colorectal cancer
US20080033985A1 (en) * 2006-06-09 2008-02-07 Gulfstream Bioinformatics Corporation Biomedical Information Modeling
US7700756B2 (en) * 2006-07-27 2010-04-20 Southern Illinois University Metabolic primers for the detection of perchlorate-reducing bacteria and methods of use thereof
CA2658991A1 (en) * 2006-07-28 2008-01-31 Ingenuity Systems, Inc. Genomics based targeted advertising
CA2660286A1 (en) 2006-08-09 2008-02-21 Homestead Clinical Corporation Organ-specific proteins and methods of their use
WO2008048120A2 (en) * 2006-10-17 2008-04-24 Synergenz Bioscience Limited Methods and compositions for assessment of pulmonary function and disorders
US9845494B2 (en) 2006-10-18 2017-12-19 Affymetrix, Inc. Enzymatic methods for genotyping on arrays
EP2092074A4 (de) 2006-11-02 2010-06-09 Univ Yale Beurteilung der befruchtungsfähigkeit von eizellen
NZ551157A (en) * 2006-11-08 2008-06-30 Rebecca Lee Roberts Method of identifying individuals at risk of thiopurine drug resistance and intolerance - GMPS
US8293684B2 (en) * 2006-11-29 2012-10-23 Exiqon Locked nucleic acid reagents for labelling nucleic acids
US7902345B2 (en) 2006-12-05 2011-03-08 Sequenom, Inc. Detection and quantification of biomolecules using mass spectrometry
AU2007334740A1 (en) * 2006-12-19 2008-06-26 Synergenz Bioscience Limited Methods and compositions for the assessment of cardiovascular function and disorders
US7838234B2 (en) 2007-01-30 2010-11-23 Pharmacyclics, Inc. Methods for determining cancer resistance to histone deacetylase inhibitors
EP2118298B1 (de) 2007-02-08 2013-01-09 Sequenom, Inc. Tests auf nukleinsäurebasis für rhd-typisierung
US9581595B2 (en) 2007-02-26 2017-02-28 Laboratory Corporation Of America Holdings Compositions and methods for determining whether a subject would benefit from co-receptor inhibitor therapy
AU2008222563A1 (en) 2007-03-05 2008-09-12 Cancer Care Ontario Assessment of risk for colorectal cancer
EP2140031A4 (de) 2007-03-26 2011-04-20 Sequenom Inc Restriktionsendonukleaseverstärkte polymorphe sequenzerfassung
US9394571B2 (en) 2007-04-27 2016-07-19 Pfenex Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US9580719B2 (en) * 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US8200440B2 (en) * 2007-05-18 2012-06-12 Affymetrix, Inc. System, method, and computer software product for genotype determination using probe array data
WO2009032781A2 (en) 2007-08-29 2009-03-12 Sequenom, Inc. Methods and compositions for universal size-specific polymerase chain reaction
US8765368B2 (en) * 2007-09-17 2014-07-01 The University Of Toledo Cancer risk biomarker
US20110045481A1 (en) 2008-01-25 2011-02-24 Patrick Gladding Methods and compositions for the assessment of drug response
US9012370B2 (en) * 2008-03-11 2015-04-21 National Cancer Center Method for measuring chromosome, gene or specific nucleotide sequence copy numbers using SNP array
WO2009114543A2 (en) 2008-03-11 2009-09-17 Sequenom, Inc. Nucleic acid-based tests for prenatal gender determination
WO2009120808A2 (en) 2008-03-26 2009-10-01 Sequenom, Inc. Restriction endonuclease enhanced polymorphic sequence detection
WO2009149297A1 (en) * 2008-06-04 2009-12-10 The Arizona Board Regents, On Behalf Of The University Of Arizona Diffuse large b-cell lymphoma markers and uses therefor
US20110201519A1 (en) 2008-08-18 2011-08-18 Sarwal Minnie M Methods and Compositions for Determining a Graft Tolerant Phenotype in a Subject
US8962247B2 (en) * 2008-09-16 2015-02-24 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
US8476013B2 (en) 2008-09-16 2013-07-02 Sequenom, Inc. Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
US20110212083A1 (en) 2008-11-06 2011-09-01 University Of Miami Office Of Technology Transfer Role of soluble upar in the pathogenesis of proteinuric kidney disease
US8039794B2 (en) 2008-12-16 2011-10-18 Quest Diagnostics Investments Incorporated Mass spectrometry assay for thiopurine-S-methyl transferase activity and products generated thereby
KR101025848B1 (ko) * 2008-12-30 2011-03-30 삼성전자주식회사 개인 유전체 통합 관리 방법 및 장치
ES2595410T3 (es) 2009-01-07 2016-12-29 Myriad Genetics, Inc. Biomarcadores de cáncer
KR20110138340A (ko) * 2009-01-20 2011-12-27 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 약물 타겟을 진단, 예후 예측 및 동정하기 위한 단일 세포 유전자 발현
IL313131A (en) 2009-02-11 2024-07-01 Caris Mpi Inc Molecular characterization of tumors
US8832581B2 (en) * 2009-03-05 2014-09-09 Ming Zhang Gene expression browser for web-based search and visualization of characteristics of gene expression
CN102428191A (zh) * 2009-03-18 2012-04-25 塞昆纳姆股份有限公司 热稳定性内切核酸酶在产生报道分子中的应用
US8771948B2 (en) 2009-04-03 2014-07-08 Sequenom, Inc. Nucleic acid preparation compositions and methods
CA2779223A1 (en) 2009-10-27 2011-05-12 Caris Mpi, Inc. Molecular profiling for personalized medicine
US20110201008A1 (en) * 2009-12-01 2011-08-18 University Of Miami Assays, methods and kits for measuring response to therapy and predicting clinical outcome in patients with b-cell lymphoma
US9290813B2 (en) 2009-12-02 2016-03-22 The Board Of Trustees Of The Leland Stanford Junior University Biomarkers for determining an allograft tolerant phenotype
US8501122B2 (en) 2009-12-08 2013-08-06 Affymetrix, Inc. Manufacturing and processing polymer arrays
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
DK2516680T3 (en) 2009-12-22 2016-05-02 Sequenom Inc Method and kits to identify aneuploidy
US9798855B2 (en) 2010-01-07 2017-10-24 Affymetrix, Inc. Differential filtering of genetic data
WO2011091435A2 (en) 2010-01-25 2011-07-28 Mount Sinai School Of Medicine Methods of treating liver disease
CA2794255C (en) 2010-03-25 2020-01-14 The Board Of Trustees Of The Leland Stanford Junior University Protein and gene biomarkers for rejection of organ transplants
CA2797093C (en) 2010-04-26 2019-10-29 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-trna synthetase
CA2797362C (en) 2010-04-27 2020-12-08 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl trna synthetases
WO2011139853A2 (en) 2010-04-28 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl trna synthetases
US8986680B2 (en) 2010-04-29 2015-03-24 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Asparaginyl tRNA synthetases
EP2563383B1 (de) 2010-04-29 2017-03-01 Atyr Pharma, Inc. Innovative entdeckung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen im zusammenhang mit proteinfragmenten von valyl-trna-synthetasen
CA2797977C (en) 2010-05-03 2019-08-20 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-trna synthetases
WO2011139986A2 (en) 2010-05-03 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of arginyl-trna synthetases
CN103140233B (zh) 2010-05-03 2017-04-05 Atyr 医药公司 与甲硫氨酰‑tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现
EP2566499B1 (de) 2010-05-04 2017-01-25 aTyr Pharma, Inc. Innovative entdeckung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen im zusammenhang mit proteinfragmenten aus einem p38-multi-trna-synthetase-komplex
CA2799197C (en) 2010-05-14 2019-10-29 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-trna synthetases
AU2011258106B2 (en) 2010-05-27 2017-02-23 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-tRNA synthetases
CN103118694B (zh) 2010-06-01 2016-08-03 Atyr医药公司 与赖氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现
EP3812469A1 (de) 2010-07-07 2021-04-28 Myriad Genetics, Inc. Gensignaturen für krebsprognosen
JP6116479B2 (ja) 2010-07-12 2017-04-19 エータイアー ファーマ， インコーポレイテッド グリシルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
JP5964304B2 (ja) 2010-08-25 2016-08-03 エータイアー ファーマ， インコーポレイテッド チロシルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
US20120075325A1 (en) * 2010-09-09 2012-03-29 Abbott Laboratories Systems and methods for displaying molecular probes and chromosomes
EP2975399B1 (de) 2010-09-15 2022-05-11 Almac Diagnostic Services Limited Molekularer diagnosetest auf krebs
WO2012149339A2 (en) 2011-04-29 2012-11-01 Sequenom, Inc. Quantification of a minority nucleic acid species
EP2807271B1 (de) 2012-01-24 2018-08-22 CD Diagnostics, Inc. System zum nachweis einer infektion in der synovialflüssigkeit
EP2814514B1 (de) 2012-02-16 2017-09-13 Atyr Pharma, Inc. Histidyl-trna-synthetasen zur behandlung von autoimmun- und entzündungserkrankungen
WO2013130512A2 (en) 2012-02-27 2013-09-06 The University Of North Carolina At Chapel Hill Methods and uses for molecular tags
EP3321378B1 (de) 2012-02-27 2021-11-10 Becton, Dickinson and Company Zusammensetzungen für molekularen zählung
EP4155401A1 (de) 2012-03-02 2023-03-29 Sequenom, Inc. Verfahren und prozesse zur nichtinvasiven beurteilung genetischer variationen
US10504613B2 (en) 2012-12-20 2019-12-10 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
US9920361B2 (en) 2012-05-21 2018-03-20 Sequenom, Inc. Methods and compositions for analyzing nucleic acid
WO2013184905A1 (en) 2012-06-06 2013-12-12 Myriad Genetics, Inc. Hereditary cancer genes
US20140093873A1 (en) 2012-07-13 2014-04-03 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
US8766754B2 (en) 2012-07-18 2014-07-01 The Regents Of The University Of California Concave nanomagnets with widely tunable anisotropy
ES2938766T3 (es) 2012-11-16 2023-04-14 Myriad Genetics Inc Firmas génicas para el pronóstico de cáncer
CN104937111B (zh) 2012-11-27 2018-05-11 智利天主教教皇大学 用于诊断甲状腺肿瘤的组合物和方法
US9896728B2 (en) 2013-01-29 2018-02-20 Arcticrx Ltd. Method for determining a therapeutic approach for the treatment of age-related macular degeneration (AMD)
EP3597774A1 (de) 2013-03-13 2020-01-22 Sequenom, Inc. Primer zur analyse der dna-methylierung
US10535420B2 (en) 2013-03-15 2020-01-14 Affymetrix, Inc. Systems and methods for probe design to detect the presence of simple and complex indels
US11021752B2 (en) 2013-03-15 2021-06-01 Myriad Genetics, Inc. Genes and gene signatures for diagnosis and treatment of melanoma
KR101520615B1 (ko) 2013-03-20 2015-05-18 서울대학교산학협력단 간암 진단용 바이오 마커
US10390724B2 (en) 2013-06-26 2019-08-27 The Penn State Research Foundation Three-dimensional bio-medical probe sensing and contacting structures with addressibility and tunability
MX2016001854A (es) 2013-08-12 2016-09-06 Genentech Inc Composiciones y metodo para tratar condiciones asociadas con el complemento.
KR101527283B1 (ko) 2013-08-13 2015-06-10 서울대학교산학협력단 당단백질의 탈당화 검출을 통한 암 마커 스크리닝 방법 및 간세포암 마커
TW202239429A (zh) 2014-02-08 2022-10-16 美商建南德克公司 治療阿茲海默症之方法
WO2015138774A1 (en) 2014-03-13 2015-09-17 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
CN106460071B (zh) 2014-04-22 2021-09-10 一龙公司 增强和/或预测dna扩增的组合物和方法
CA2947624A1 (en) 2014-05-13 2015-11-19 Myriad Genetics, Inc. Gene signatures for cancer prognosis
EP3164508B1 (de) 2014-07-02 2023-06-07 Myriad myPath, LLC Gene und gensignaturen zur diagnose und behandlung von melanomen
WO2016061252A1 (en) 2014-10-14 2016-04-21 The University Of North Carolina At Chapel Hill Methods and compositions for prognostic and/or diagnostic subtyping of pancreatic cancer
BR112017008082A2 (pt) 2014-10-20 2017-12-26 Envirologix Inc composições e métodos para detectar um vírus de rna
US11610644B2 (en) 2014-10-24 2023-03-21 Koninklijke Philips N.V. Superior bioinformatics process for identifying at risk subject populations
CA2965217A1 (en) 2014-10-24 2016-04-28 Koninklijke Philips N.V. Medical prognosis and prediction of treatment response using multiple cellular signaling pathway activities
CN107077536B (zh) 2014-10-24 2021-09-28 皇家飞利浦有限公司 使用靶基因表达的数学建模评价TGF-β细胞信号传导途径的活性
CA2975328A1 (en) 2015-01-30 2016-08-04 Envirologix Inc. Substrates for a nicking and extension reaction
US10953370B2 (en) 2015-02-05 2021-03-23 The Penn State Research Foundation Nano-pore arrays for bio-medical, environmental, and industrial sorting, filtering, monitoring, or dispensing
WO2016166800A1 (ja) * 2015-04-13 2016-10-20 国立研究開発法人産業技術総合研究所 実験データ記録装置、コンピュータプログラム、実験データ、実験データ記録方法、実験データ表示装置及び実験データ表示方法
GB201512869D0 (en) 2015-07-21 2015-09-02 Almac Diagnostics Ltd Gene signature for minute therapies
EP3331572A4 (de) 2015-08-04 2019-05-01 CD Diagnostics, Inc. Verfahren zur erkennung von unerwünschter lokaler gewebereaktionsnekrose
KR102618536B1 (ko) * 2015-08-12 2023-12-27 삼성전자주식회사 환자의 개인화된 치료를 위한 돌연변이 우선순위화 방법 및 장치
US10720227B2 (en) * 2015-08-12 2020-07-21 Samsung Electronics Co., Ltd. Method and device for mutation prioritization for personalized therapy
CA2995520A1 (en) 2015-08-14 2017-02-23 Hendrik Jan VAN OOIJEN Assessment of nfkb cellular signaling pathway activity using mathematical modelling of target gene expression
CN108138226B (zh) 2015-10-18 2022-02-11 阿费梅特里克斯公司 单核苷酸多态性和插入缺失的多等位基因基因分型
WO2017087819A1 (en) 2015-11-19 2017-05-26 Myriad Genetics, Inc. Signatures for predicting cancer immune therapy response
US9836444B2 (en) * 2015-12-10 2017-12-05 International Business Machines Corporation Spread cell value visualization
CA3010240A1 (en) 2016-01-06 2017-07-13 Alexander Gutin Genes and gene signatures for diagnosis and treatment of melanoma
US20190128895A1 (en) 2016-04-20 2019-05-02 Ldx Prognostics Limited Co. Methods and compositions for prognosing preterm birth
WO2017193062A1 (en) 2016-05-06 2017-11-09 Myriad Genetics, Inc. Gene signatures for renal cancer prognosis
WO2017197573A1 (en) 2016-05-17 2017-11-23 Ldx Prognostics Limited Co. Methods and compositions for providing preeclampsia assessment
CN106066948B (zh) * 2016-06-07 2018-09-28 北京大学 一种基因表达量的展现方法及装置
WO2018063444A1 (en) * 2016-09-27 2018-04-05 Bae Systems Information And Electronic Systems Integration Inc. Techniques for implementing a portable spectrum analyzer
US12300357B2 (en) * 2016-12-14 2025-05-13 FlowJo, LLC Applied computer technology for management, synthesis, visualization, and exploration of parameters in large multi-parameter data sets
KR102116178B1 (ko) 2017-05-10 2020-05-27 서울대학교산학협력단 간암 고위험군의 간암 발병 모니터링 또는 진단용 바이오마커 및 그 용도
WO2018217933A1 (en) 2017-05-25 2018-11-29 FlowJo, LLC Visualization, comparative analysis, and automated difference detection for large multi-parameter data sets
US12637716B1 (en) 2017-06-02 2026-05-26 Myriad Genetics, Inc. Detecting cancer risk
US12577622B2 (en) 2017-06-02 2026-03-17 Myriad Genetics, Inc. Detecting cancer risk
WO2019005763A1 (en) 2017-06-26 2019-01-03 Phase Genomics Inc. METHOD FOR REGROUPING DNA SEQUENCES
EP3461916A1 (de) 2017-10-02 2019-04-03 Koninklijke Philips N.V. Beurteilung der zellulären jak-stat3-signalisierungspfadaktivität mittels mathematischer modellierung der zielgenexpression
EP3461915A1 (de) 2017-10-02 2019-04-03 Koninklijke Philips N.V. Beurteilung der aktivität von zellulären jak-stat1/2-signalisierungspfaden mittels mathematischer modellierung der zielgenexpression
EP3502279A1 (de) 2017-12-20 2019-06-26 Koninklijke Philips N.V. Beurteilung der aktivität von zellulären mapk-ap 1-signalisierungspfaden mittels mathematischer modellierung der zielgenexpression
US20190211098A1 (en) 2017-12-22 2019-07-11 Genentech, Inc. Use of pilra binding agents for treatment of a disease
GB2574582A (en) * 2018-05-28 2019-12-18 Rainer Gabriel Schweiger Martin Method for simulating a technical device
EP4600742A3 (de) 2018-05-29 2026-03-11 Centrillion Technologies, Inc. Erhöhung der effizienz photochemischer reaktionen auf substraten
US20210269862A1 (en) 2018-06-18 2021-09-02 Igenomix, S.L. Methods for assessing endometrial transformation
EP3864165A4 (de) 2018-10-09 2022-08-03 Genecentric Therapeutics, Inc. Nachweis von ursprungskrebszellen
KR20210111254A (ko) 2018-11-30 2021-09-10 캐리스 엠피아이, 아이엔씨. 차세대 분자 프로파일링
EP3931318A4 (de) 2019-04-01 2022-12-07 The University of North Carolina at Chapel Hill Reinheitsunabhängige subtypisierung von tumoren (purin), plattform und probentyp unabhängiger einzelprobenklassifikator zur behandlung von pankreaskrebs
CN114051537A (zh) 2019-04-17 2022-02-15 艾基诺米公司 用于早期诊断子宫平滑肌瘤和平滑肌肉瘤的改进方法
IL293489A (en) 2019-12-02 2022-08-01 Caris Mpi Inc predictor of pan-cancer platinum response
WO2023178295A1 (en) 2022-03-18 2023-09-21 Ludwig Institute For Cancer Research Ltd Methods and systems for analyzing chromatins

Family Cites Families (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
NO870613L (no) 1986-03-05 1987-09-07 Molecular Diagnostics Inc Deteksjon av mikroorganismer i en prŸve inneholdende nukleinsyre.
US4740611A (en) * 1986-10-30 1988-04-26 The Standard Oil Company N,N'-disubstituted ureas
US4705864A (en) * 1986-11-10 1987-11-10 The Standard Oil Company Aryl oxime derivatives of hydantoins
AU1042488A (en) 1986-12-20 1988-07-15 Kukita, Takeshi Bilirubin antigen, monoclonal antibody therefor, process for their preparation, and their use
US5525464A (en) 1987-04-01 1996-06-11 Hyseq, Inc. Method of sequencing by hybridization of oligonucleotide probes
US5202231A (en) 1987-04-01 1993-04-13 Drmanac Radoje T Method of sequencing of genomes by hybridization of oligonucleotide probes
US5700637A (en) 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
JP2897959B2 (ja) 1988-05-20 1999-05-31 エフ．ホフマン―ラ ロシュ アクチェンゲゼルシャフト 固定化された配列特異的プローブ
US5206137A (en) * 1988-09-08 1993-04-27 Lifecodes Corporation Compositions and methods useful for genetic analysis
US6203977B1 (en) * 1988-11-15 2001-03-20 Yale University Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization
EP0392546A3 (de) 1989-04-14 1991-09-11 Ro Institut Za Molekularnu Genetiku I Geneticko Inzenjerstvo Verfahren zur Bestimmung von vollständigen oder partiellen Bestandteilen von sehr kurzen Sequenzen in Proben von Partikeln mikroskopischer Grösse mittels Hybridisierung mit Oligonukleotid-Sonden
US6040138A (en) * 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
US5925525A (en) * 1989-06-07 1999-07-20 Affymetrix, Inc. Method of identifying nucleotide differences
US5800992A (en) * 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5871928A (en) * 1989-06-07 1999-02-16 Fodor; Stephen P. A. Methods for nucleic acid analysis
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
DE69132905T2 (de) 1990-12-06 2002-08-01 Affymetrix, Inc. (N.D.Ges.D.Staates Delaware) Detektion von Nukleinsäuresequenzen
DK0562025T3 (da) 1990-12-06 2001-06-18 Affymetrix Inc Forbindelser og deres anvendelse i en binær syntesestrategi
GR1000797B (el) 1991-06-10 1993-01-25 Emmanouil E Petromanolakis Αποσβεστηρας ενεργειας κυματισμου κατα την προωση ενος πλοιου.
JP3698369B2 (ja) * 1991-08-13 2005-09-21 ウィスコンシン ミルク マーケティング ボード αラクトアルブミンを符号化するＤＮＡ配列及び使用方法
US5846717A (en) * 1996-01-24 1998-12-08 Third Wave Technologies, Inc. Detection of nucleic acid sequences by invader-directed cleavage
CA2134552A1 (en) 1992-04-27 1993-11-11 George D. Sorenson Detection of gene sequences in biological fluids
US6251920B1 (en) * 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6395494B1 (en) * 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
US5524070A (en) * 1992-10-07 1996-06-04 The Research Foundation Of State University Of New York Local adaptive contrast enhancement
WO1995011995A1 (en) 1993-10-26 1995-05-04 Affymax Technologies N.V. Arrays of nucleic acid probes on biological chips
US5632282A (en) * 1993-07-20 1997-05-27 Hay; S. Hutson Ocular disease detection apparatus
WO1995011755A1 (en) 1993-10-28 1995-05-04 Houston Advanced Research Center Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions
US6096503A (en) * 1993-11-12 2000-08-01 The Scripps Research Institute Method for simultaneous identification of differentially expresses mRNAs and measurement of relative concentrations
US6339767B1 (en) * 1997-06-02 2002-01-15 Aurigin Systems, Inc. Using hyperbolic trees to visualize data generated by patent-centric and group-oriented data processing
EP0667586A3 (de) * 1994-02-14 1996-08-28 Digital Equipment Corp System zur Erzeugung von Datenbanken.
US5560005A (en) * 1994-02-25 1996-09-24 Actamed Corp. Methods and systems for object-based relational distributed databases
US5571639A (en) 1994-05-24 1996-11-05 Affymax Technologies N.V. Computer-aided engineering system for design of sequence arrays and lithographic masks
US5570291A (en) * 1994-08-24 1996-10-29 Wallace Computer Services, Inc. Custom product estimating and order processing system
US6600996B2 (en) 1994-10-21 2003-07-29 Affymetrix, Inc. Computer-aided techniques for analyzing biological sequences
US5795716A (en) * 1994-10-21 1998-08-18 Chee; Mark S. Computer-aided visualization and analysis system for sequence evaluation
WO1997027317A1 (en) 1996-01-23 1997-07-31 Affymetrix, Inc. Nucleic acid analysis techniques
CA2210731A1 (en) 1995-01-27 1996-08-01 Incyte Pharmaceuticals, Inc. Computer system storing and analyzing microbiological data
US5961923A (en) * 1995-04-25 1999-10-05 Irori Matrices with memories and uses thereof
EP0747418B1 (de) * 1995-06-06 2002-07-03 Ube Industries, Ltd. Aromatische Polyimid und Gastrennung
US5707806A (en) 1995-06-07 1998-01-13 Genzyme Corporation Direct sequence identification of mutations by cleavage- and ligation-associated mutation-specific sequencing
US5777888A (en) 1995-08-09 1998-07-07 Regents Of The University Of California Systems for generating and analyzing stimulus-response output signal matrices
US5871697A (en) 1995-10-24 1999-02-16 Curagen Corporation Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
GB9522615D0 (en) 1995-11-03 1996-01-03 Pharmacia Spa 4-Phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibiting activity
US5778200A (en) 1995-11-21 1998-07-07 Advanced Micro Devices, Inc. Bus arbiter including aging factor counters to dynamically vary arbitration priority
WO1997029212A1 (en) 1996-02-08 1997-08-14 Affymetrix, Inc. Chip-based speciation and phenotypic characterization of microorganisms
US6108635A (en) * 1996-05-22 2000-08-22 Interleukin Genetics, Inc. Integrated disease information system
US5989835A (en) * 1997-02-27 1999-11-23 Cellomics, Inc. System for cell-based screening
AU722989B2 (en) * 1996-11-04 2000-08-17 3-Dimensional Pharmaceuticals, Inc. System, method, and computer program product for the visualization and interactive processing and analysis of chemical data
US5968784A (en) * 1997-01-15 1999-10-19 Chugai Pharmaceutical Co., Ltd. Method for analyzing quantitative expression of genes
US6205447B1 (en) * 1997-06-30 2001-03-20 International Business Machines Corporation Relational database management of multi-dimensional data
US6484183B1 (en) 1997-07-25 2002-11-19 Affymetrix, Inc. Method and system for providing a polymorphism database
US6032151A (en) * 1997-11-17 2000-02-29 Sun Microsystems, Inc. Database system employing polymorphic entry and entry matching
US6025194A (en) * 1997-11-19 2000-02-15 Geron Corporation Nucleic acid sequence of senescence asssociated gene
US5991766A (en) * 1997-12-02 1999-11-23 Electronic Data Systems Corporation Method and system for managing redundant objects in a distributed object system
US20030036855A1 (en) * 1998-03-16 2003-02-20 Praelux Incorporated, A Corporation Of New Jersey Method and apparatus for screening chemical compounds
US6324533B1 (en) * 1998-05-29 2001-11-27 International Business Machines Corporation Integrated database and data-mining system
AU2342900A (en) * 1998-09-23 2000-05-01 Cleveland Clinic Foundation, The Novel interferon stimulated and repressed genes
US6140054A (en) * 1998-09-30 2000-10-31 University Of Utah Research Foundation Multiplex genotyping using fluorescent hybridization probes
US6251601B1 (en) * 1999-02-02 2001-06-26 Vysis, Inc. Simultaneous measurement of gene expression and genomic abnormalities using nucleic acid microarrays
US6284465B1 (en) * 1999-04-15 2001-09-04 Agilent Technologies, Inc. Apparatus, systems and method for locating nucleic acids bound to surfaces
US6338071B1 (en) * 1999-08-18 2002-01-08 Affymetrix, Inc. Method and system for providing a contract management system using an action-item table
US6754666B1 (en) * 1999-08-19 2004-06-22 A2I, Inc. Efficient storage and access in a database management system
AU6909300A (en) * 1999-08-20 2001-03-19 Merck & Co., Inc. Substituted ureas as cell adhesion inhibitors
US7072896B2 (en) * 2000-02-16 2006-07-04 Verizon Laboratories Inc. System and method for automatic loading of an XML document defined by a document-type definition into a relational database including the generation of a relational schema therefor
US6569615B1 (en) * 2000-04-10 2003-05-27 The United States Of America As Represented By The Department Of Veteran's Affairs Composition and methods for tissue preservation
US20020062258A1 (en) * 2000-05-18 2002-05-23 Bailey Steven C. Computer-implemented procurement of items using parametric searching
US7731904B2 (en) * 2000-09-19 2010-06-08 Canon Kabushiki Kaisha Method for making probe support and apparatus used for the method
US6872533B2 (en) * 2001-07-27 2005-03-29 The Regents Of The University Of California STK15 (STK6) gene polymorphism and methods of determining cancer risk
US20030126139A1 (en) * 2001-12-28 2003-07-03 Lee Timothy A. System and method for loading commercial web sites

Also Published As

Publication number Publication date
EP1009861A4 (de) 2002-10-16
US20030125882A1 (en) 2003-07-03
DE69823206T2 (de) 2004-08-19
US20020012456A1 (en) 2002-01-31
WO1999005323A1 (en) 1999-02-04
JP2005353057A (ja) 2005-12-22
US6567540B2 (en) 2003-05-20
JP2005100389A (ja) 2005-04-14
WO1999005324A1 (en) 1999-02-04
EP0998697A4 (de) 2002-07-24
WO1999005574A1 (en) 1999-02-04
JP2001511529A (ja) 2001-08-14
EP1009861A1 (de) 2000-06-21
US6229911B1 (en) 2001-05-08
EP0998697A1 (de) 2000-05-10
JP2001515234A (ja) 2001-09-18
JP2001511546A (ja) 2001-08-14
US6532462B2 (en) 2003-03-11
WO1999005591A2 (en) 1999-02-04
US20050164270A1 (en) 2005-07-28
US6882742B2 (en) 2005-04-19
DE69823206D1 (de) 2004-05-19
EP1002264A2 (de) 2000-05-24
EP1007737A1 (de) 2000-06-14
US20050157915A1 (en) 2005-07-21
EP1002264B1 (de) 2004-04-14
US6484183B1 (en) 2002-11-19
JP3776728B2 (ja) 2006-05-17
US20020062319A1 (en) 2002-05-23
US7215804B2 (en) 2007-05-08
US20030074363A1 (en) 2003-04-17
EP1002264A4 (de) 2002-07-03
US6308170B1 (en) 2001-10-23
WO1999005591A3 (en) 1999-05-20
JP2001511550A (ja) 2001-08-14
US6188783B1 (en) 2001-02-13
EP1007737A4 (de) 2002-07-03

Similar Documents

Publication Publication Date Title
DE69823206D1 (de) Verfahren zur herstellung einer bio-informatik-datenbank
ATE98773T1 (de) Verfahren zur optischen analyse.
DE3689856D1 (de) Analyseverfahren und vorrichtung für biologische specimen.
BR0214367A (pt) métodos implementados em computador para a análise de dados de imagem, para criar um relatório pertencendo à análise de diagnóstico de dados de imagem, e para análise de uma imagem, sistema para a análise de dados de imagem, e, sistema de computador para análise de uma imagem
ATE496288T1 (de) Gleichzeitige mehrfachanalyse klinischer proben
IT1270130B (it) Strumento diagnostico automatizzato in particolare per l'analisi di campioni in pacchi di prova per un analita
DE3875456D1 (de) Verfahren zur analyse haematopoietischer zellen in einer probe.
ES556820A0 (es) Un conjunto de bandeja de especimenes para uso en un sistema automatizado de analisis, para analizar dichos especimenes
DE59108006D1 (de) Vorrichtung zur Vorbereitung von Proben insbesondere für Analysezwecke
DE3768533D1 (de) Verfahren zur massenanalyse einer probe.
DE58909018D1 (de) Testträger für die Analyse einer Probenflüssigkeit, Verfahren zur Durchführung einer solchen Analyse und Herstellungsverfahren.
DE3769002D1 (de) Verfahren und vorrichtung zur ummantelung eines optischen vorform-stabes.
ATE318930T1 (de) Nukleinsäuresonden zur detektion von candida- spezies
FI874129L (fi) Analyysiväline biologiselle nesteelle
DE69000071D1 (de) Vorrichtung zur dynamischen torsionspruefung einer probe.
Cleaver DNA repair processes and their impairment in some human diseases
EP0382261A3 (de) DNS-Sonden gegen VNTR-Orte
DE3763624D1 (de) Verfahren und vorrichtung zur chromatographischen analyse, insbesondere von erdoelfluessigkeiten.
EP1396800A3 (de) Verfahren und Vorrichtung zur Herstellung einer Bio-Informatik-Datenbank
SE9601812D0 (sv) Improvements in, or Relating to, Speech-To-Speech Conversion
DE59010149D1 (de) Vorrichtung zur Vorbereitung von Gasproben für die Analyse
WO1988004454A3 (en) Information retrieval system and method
DE69011917D1 (de) Vorrichtung für die automatische Gültigkeitsanalyse von medizinischen Prüfdaten.
DE68925457D1 (de) Diagnoseverfahren für infektionskrankheiten sowie verfahren zum nachweis und identifizierung von mikroorganismen
Rasmussen Molecular taxonomy and typology

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties