ATE264718T1 - Microchip-matrix-vorrichtung zur vervielfältigung und charakterisierung von nukleinsäuren - Google Patents
Microchip-matrix-vorrichtung zur vervielfältigung und charakterisierung von nukleinsäurenInfo
- Publication number
- ATE264718T1 ATE264718T1 AT00952983T AT00952983T ATE264718T1 AT E264718 T1 ATE264718 T1 AT E264718T1 AT 00952983 T AT00952983 T AT 00952983T AT 00952983 T AT00952983 T AT 00952983T AT E264718 T1 ATE264718 T1 AT E264718T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acids
- chip
- chamber
- chamber support
- chamber body
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
- B01F33/3031—Micromixers using electro-hydrodynamic [EHD] or electro-kinetic [EKI] phenomena to mix or move the fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Rigid containers without fluid transport within
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/142—Preventing evaporation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
- B01L2400/0418—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electro-osmotic flow [EOF]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Dispersion Chemistry (AREA)
- Fluid Mechanics (AREA)
- Physics & Mathematics (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19932423 | 1999-07-02 | ||
| PCT/EP2000/006103 WO2001002094A1 (de) | 1999-07-02 | 2000-06-30 | Microchip-matrix-vorrichtung zur vervielfältigung und charakterisierung von nukleinsäuren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE264718T1 true ATE264718T1 (de) | 2004-05-15 |
Family
ID=7914426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00952983T ATE264718T1 (de) | 1999-07-02 | 2000-06-30 | Microchip-matrix-vorrichtung zur vervielfältigung und charakterisierung von nukleinsäuren |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7888074B2 (de) |
| EP (1) | EP1192007B1 (de) |
| AT (1) | ATE264718T1 (de) |
| AU (1) | AU768113B2 (de) |
| CA (1) | CA2379125C (de) |
| DE (1) | DE50006164D1 (de) |
| ES (1) | ES2219374T3 (de) |
| HK (1) | HK1046381A1 (de) |
| IL (2) | IL147227A0 (de) |
| WO (1) | WO2001002094A1 (de) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6677131B2 (en) * | 2001-05-14 | 2004-01-13 | Corning Incorporated | Well frame including connectors for biological fluids |
| DE10132785A1 (de) * | 2001-07-06 | 2003-01-16 | Clondiag Chip Tech Gmbh | Verfahren zum Nachweis von in einer Polymerase-Kettenreaktion amplifizierten Nukleinsäuremolekülen |
| US6893822B2 (en) | 2001-07-19 | 2005-05-17 | Nanogen Recognomics Gmbh | Enzymatic modification of a nucleic acid-synthetic binding unit conjugate |
| EP1281439A1 (de) * | 2001-07-30 | 2003-02-05 | F. Hoffmann-La Roche Ag | Vorrichtung zur Aufnahme eines chipförmigen Trägers und Verfahren zum Zusammenbau mehrerer solcher Vorrichtungen |
| DE10149684B4 (de) * | 2001-10-09 | 2005-02-17 | Clondiag Chip Technologies Gmbh | Vorrichtung zur Halterung eines Substanzbibliothekenträgers |
| DE10152690A1 (de) * | 2001-10-19 | 2003-05-08 | Genescan Europ Ag | Durchflussreaktionskammer für Sensorchips |
| US6756223B2 (en) * | 2001-12-18 | 2004-06-29 | Motorola, Inc. | Electro-chemical analysis device with integrated thermal sensor and method for monitoring a sample using the device |
| DE10201463B4 (de) | 2002-01-16 | 2005-07-21 | Clondiag Chip Technologies Gmbh | Reaktionsgefäß zur Durchführung von Array-Verfahren |
| CN1217003C (zh) * | 2003-02-20 | 2005-08-31 | 北京博奥生物芯片有限责任公司 | 一种微阵列反应装置及其应用 |
| DE10315074A1 (de) * | 2003-04-02 | 2004-10-14 | Clondiag Chip Technologies Gmbh | Vorrichtung zur Vervielfältigung und zum Nachweis von Nukleinsäuren |
| DE10316723A1 (de) * | 2003-04-09 | 2004-11-18 | Siemens Ag | Probenplatte zum Einbau in eine Gehäusestruktur |
| JP4656057B2 (ja) * | 2003-04-10 | 2011-03-23 | 株式会社ニコン | 液浸リソグラフィ装置用電気浸透素子 |
| DE10318219A1 (de) * | 2003-04-22 | 2004-11-11 | Febit Ag | Handhabungs- und Schutzgehäuse für einen Biochip, insbesondere für einen mikrofluidischen Reaktionsträger |
| DE10323197B4 (de) * | 2003-05-22 | 2008-10-02 | Clondiag Chip Technologies Gmbh | Vorrichtung zur Halterung und Detektion von Substanzbibliotheken |
| CN1289904C (zh) | 2003-08-01 | 2006-12-13 | 博奥生物有限公司 | 一种微阵列反应装置及其应用 |
| DE10336849A1 (de) | 2003-08-11 | 2005-03-10 | Thinxxs Gmbh | Flusszelle |
| DE10338837A1 (de) * | 2003-08-21 | 2004-11-11 | Infineon Technologies Ag | Verfahren zum Herstellen einer Vorrichtung zur Vervielfältigung und Charakterisierung von Nukleinsäuren sowie Trägerwafer für Biochips |
| DE10352888A1 (de) * | 2003-11-10 | 2005-05-04 | Infineon Technologies Ag | DNA-Chip-Array-Prozessor mit anisotrop elektrisch leitender elastischer Kontaktierung |
| EP1541991A1 (de) * | 2003-12-12 | 2005-06-15 | STMicroelectronics S.r.l. | Integrierter chemischer Reaktor aus Halbleitermaterial zur Echtzeit-Überwachung von biologischen Reaktionen |
| DE10359160A1 (de) * | 2003-12-16 | 2005-07-21 | Roche Diagnostics Gmbh | Testelement zur Untersuchung von Probenmaterial |
| DE102004003860A1 (de) | 2004-01-26 | 2005-08-18 | Clondiag Chip Technologies Gmbh | Verfahren zur Geno- und Pathotypisierung von Pseudomonas aeruginosa |
| DE102005052713A1 (de) | 2005-11-04 | 2007-05-16 | Clondiag Chip Tech Gmbh | Vorrichtung und Verfahren zum Nachweis von molekularen Wechselwirkungen |
| DE102004022263A1 (de) | 2004-05-06 | 2005-12-15 | Clondiag Chip Technologies Gmbh | Vorrichtung und Verfahren zum Nachweis von molekularen Wechselwirkungen |
| DE102005052752A1 (de) | 2005-11-04 | 2007-05-10 | Clondiag Chip Technologies Gmbh | Vorrichtung und Verfahren zum Nachweis von molekularen Wechselwirkungen |
| US8053214B2 (en) * | 2004-09-09 | 2011-11-08 | Microfluidic Systems, Inc. | Apparatus and method of extracting and optically analyzing an analyte from a fluid-based sample |
| DE102004056735A1 (de) | 2004-11-09 | 2006-07-20 | Clondiag Chip Technologies Gmbh | Vorrichtung für die Durchführung und Analyse von Mikroarray-Experimenten |
| JP4810093B2 (ja) * | 2004-12-28 | 2011-11-09 | オリンパス株式会社 | 培養観察装置および標本トレー保温装置および蓋 |
| USD545320S1 (en) * | 2005-09-23 | 2007-06-26 | Romero Dennis F | Copying-prevention software chip for embedding in compact disc |
| US7705739B2 (en) * | 2006-08-24 | 2010-04-27 | Microfluidic Systems, Inc. | Integrated airborne substance collection and detection system |
| US7858366B2 (en) * | 2006-08-24 | 2010-12-28 | Microfluidic Systems, Inc | Integrated airborne substance collection and detection system |
| EP2548647B1 (de) | 2006-10-20 | 2018-08-15 | CLONDIAG GmbH | Testvorrichtungen und-Verfahren zum Nachweis von Analyten |
| WO2008055915A2 (en) | 2006-11-06 | 2008-05-15 | Clondiag Gmbh | Device and process for assays using binding members |
| DE102007031526B4 (de) | 2007-07-06 | 2010-07-08 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verwendung einer Anode in einer Brennstoffzelle zur Oxidation von Ethanol und/oder zumindest eines C3 bis C10-haltigen Alkohols |
| AU2008280121B2 (en) | 2007-07-23 | 2015-02-26 | Clondiag Gmbh | Assays |
| DE102007052281A1 (de) * | 2007-11-02 | 2009-05-07 | Zenteris Gmbh | Einschritt-Multiplex-Immuntest |
| EP2391452B1 (de) * | 2009-01-30 | 2015-06-17 | Gen-Probe Incorporated | Systeme und verfahren zur erfassung eines signals und beaufschlagung des signalübertragungselements mit wärmeenergie |
| DE102009061008B4 (de) * | 2009-03-20 | 2014-09-25 | Retina Implant Ag | Verwendung einer Testvorrichtung und Verfahren zum Test von Zellen, Zellkulturen und/oder organotypischen Zellverbänden |
| US9199080B2 (en) | 2011-09-12 | 2015-12-01 | Okuvision Gmbh | Method for treating an eye |
| EP2825865B1 (de) | 2012-03-09 | 2020-07-22 | Ubiquitome Limited | Tragbare vorrichtung zur erkennung von molekülen |
| MX350425B (es) | 2012-06-28 | 2017-09-05 | Fluoresentric Inc | Dispositivo de indicador quimico. |
| DE102012108158B4 (de) | 2012-09-03 | 2016-03-17 | Johann Wolfgang Goethe-Universität | Kapillarzelle, Anordnung und Verfahren zur Aufnahme, zur Positionierung und zur Untersuchung einer mikroskopischen Probe |
| DE102012219656A1 (de) * | 2012-10-26 | 2014-04-30 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | System zur durchführung einer berührungslosen messung an einer probe und probenträger |
| EP2965063A4 (de) * | 2013-03-08 | 2016-09-14 | Otago Innovation Ltd | Reaktionsgefässhalter und moleküldetektionsvorrichtung |
| GB201403076D0 (en) | 2014-02-21 | 2014-04-09 | ALERE TECHNOLOGIES GmbH | Methods for detecting multiple nucleic acids in a sample |
| EP4109095A1 (de) * | 2014-09-09 | 2022-12-28 | Perosphere Technologies Inc. | Auf mikrofluidischem chip basierender universeller koagulationstest |
| FR3038383B1 (fr) * | 2015-07-03 | 2017-07-07 | Avalun | Appareil d’analyse d’un echantillon liquide comportant un dispositif de blocage et d’ejection |
| JP6573257B2 (ja) * | 2015-09-29 | 2019-09-11 | エア・ウォーター・バイオデザイン株式会社 | 測定装置及び測定方法 |
| US10094802B2 (en) | 2016-06-01 | 2018-10-09 | EXIAS Medical GmbH | Heating system for a measurement cell |
| US11092519B1 (en) * | 2017-02-06 | 2021-08-17 | Elemental Scientific Lasers, Llc | System and method for automated sampling and analysis |
| US20210170396A1 (en) | 2018-01-16 | 2021-06-10 | Hewlett-Packard Development Company, L.P. | Fluid testing |
| DE102019135557A1 (de) * | 2019-12-20 | 2021-06-24 | Biophotonics Diagnostics GmbH | Probenträger zur elektrischen manipulation von flüssigen proben und zur schwingungsspektroskopie an den proben |
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|---|---|---|---|---|
| US5744101A (en) * | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| KR100236506B1 (ko) * | 1990-11-29 | 2000-01-15 | 퍼킨-엘머시터스인스트루먼츠 | 폴리머라제 연쇄 반응 수행 장치 |
| US5222808A (en) * | 1992-04-10 | 1993-06-29 | Biotrack, Inc. | Capillary mixing device |
| DE69527585T2 (de) * | 1994-06-08 | 2003-04-03 | Affymetrix, Inc. | Verfahren und Vorrichtung zum Verpacken von Chips |
| US6521181B1 (en) * | 1995-06-20 | 2003-02-18 | The Regents Of The University Of Calfornia | Microfabricated electrochemiluminescence cell for chemical reaction detection |
| US5856174A (en) * | 1995-06-29 | 1999-01-05 | Affymetrix, Inc. | Integrated nucleic acid diagnostic device |
| DE69700499T2 (de) * | 1996-04-03 | 2000-03-23 | Perkin Elmer Corp | Vorrichtung und verfahren zum nachweis mehrerer analyten |
| US6054277A (en) * | 1996-05-08 | 2000-04-25 | Regents Of The University Of Minnesota | Integrated microchip genetic testing system |
| JP3077609B2 (ja) * | 1996-10-31 | 2000-08-14 | 株式会社島津製作所 | マイクロチップ電気泳動方法及び装置 |
| US5882903A (en) * | 1996-11-01 | 1999-03-16 | Sarnoff Corporation | Assay system and method for conducting assays |
| US5922604A (en) * | 1997-06-05 | 1999-07-13 | Gene Tec Corporation | Thin reaction chambers for containing and handling liquid microvolumes |
| EP1003759A2 (de) * | 1997-08-13 | 2000-05-31 | Cepheid | Mikrostrukturen für die manipulation von flüssigen proben |
| AU4546899A (en) * | 1998-06-05 | 1999-12-20 | Sarnoff Corporation | Apparatus for separating molecules |
| US6093370A (en) * | 1998-06-11 | 2000-07-25 | Hitachi, Ltd. | Polynucleotide separation method and apparatus therefor |
| EP1115424A1 (de) * | 1998-08-28 | 2001-07-18 | Febit Ferrarius Biotechnology GmbH | Verfahren und messeinrichtung zur bestimmung einer vielzahl von analyten in einer probe |
| DE19950225A1 (de) * | 1998-10-24 | 2000-05-18 | Leica Microsystems | Anordnung zur optischen Abtastung eines Objekts |
| US6284195B1 (en) * | 1999-01-25 | 2001-09-04 | Industrial Technology Research Institute | Disposable reaction module |
| US6126400A (en) * | 1999-02-01 | 2000-10-03 | General Electric Company | Thermal barrier coating wrap for turbine airfoil |
| US6878540B2 (en) * | 1999-06-25 | 2005-04-12 | Cepheid | Device for lysing cells, spores, or microorganisms |
| US6642046B1 (en) * | 1999-12-09 | 2003-11-04 | Motorola, Inc. | Method and apparatus for performing biological reactions on a substrate surface |
-
2000
- 2000-06-30 IL IL14722700A patent/IL147227A0/xx active IP Right Grant
- 2000-06-30 AU AU65599/00A patent/AU768113B2/en not_active Ceased
- 2000-06-30 CA CA002379125A patent/CA2379125C/en not_active Expired - Lifetime
- 2000-06-30 AT AT00952983T patent/ATE264718T1/de not_active IP Right Cessation
- 2000-06-30 DE DE50006164T patent/DE50006164D1/de not_active Expired - Lifetime
- 2000-06-30 EP EP00952983A patent/EP1192007B1/de not_active Expired - Lifetime
- 2000-06-30 WO PCT/EP2000/006103 patent/WO2001002094A1/de not_active Ceased
- 2000-06-30 HK HK02106805.0A patent/HK1046381A1/zh unknown
- 2000-06-30 ES ES00952983T patent/ES2219374T3/es not_active Expired - Lifetime
-
2001
- 2001-12-20 IL IL147227A patent/IL147227A/en unknown
-
2002
- 2002-01-02 US US10/038,284 patent/US7888074B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2219374T3 (es) | 2004-12-01 |
| EP1192007B1 (de) | 2004-04-21 |
| EP1192007A1 (de) | 2002-04-03 |
| WO2001002094A1 (de) | 2001-01-11 |
| US20020150933A1 (en) | 2002-10-17 |
| CA2379125A1 (en) | 2001-01-11 |
| IL147227A (en) | 2006-08-20 |
| IL147227A0 (en) | 2002-08-14 |
| CA2379125C (en) | 2009-04-07 |
| AU6559900A (en) | 2001-01-22 |
| US7888074B2 (en) | 2011-02-15 |
| HK1046381A1 (zh) | 2003-01-10 |
| WO2001002094A8 (de) | 2001-06-21 |
| AU768113B2 (en) | 2003-12-04 |
| DE50006164D1 (de) | 2004-05-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |