ATE265856T1 - Augenlösung mit tetracyclin für behandlung von trockenen augen - Google Patents

Augenlösung mit tetracyclin für behandlung von trockenen augen

Info

Publication number: ATE265856T1
Authority: AT; Austria
Prior art keywords: eye; tetracycline; solution; electrolytes; treatment
Prior art date: 1998-08-06

Application number

AT99937618T

Other languages

English (en)

Inventor

Jeffrey P Gilbard

Original Assignee

Advanced Vision Res

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-06

Filing date

1999-07-29

Publication date

2004-05-15

1999-07-29 Application filed by Advanced Vision Res filed Critical Advanced Vision Res

2004-05-15 Application granted granted Critical

2004-05-15 Publication of ATE265856T1 publication Critical patent/ATE265856T1/de

Links

208000003556 Dry Eye Syndromes Diseases 0.000 title abstract 2
206010013774 Dry eye Diseases 0.000 title abstract 2
239000004098 Tetracycline Substances 0.000 title abstract 2
229960002180 tetracycline Drugs 0.000 title abstract 2
229930101283 tetracycline Natural products 0.000 title abstract 2
235000019364 tetracycline Nutrition 0.000 title abstract 2
150000003522 tetracyclines Chemical class 0.000 title 1
239000003792 electrolyte Substances 0.000 abstract 2
BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 abstract 1
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
229920002527 Glycogen Polymers 0.000 abstract 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
206010061218 Inflammation Diseases 0.000 abstract 1
FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
229910019142 PO4 Inorganic materials 0.000 abstract 1
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
239000007864 aqueous solution Substances 0.000 abstract 1
239000011575 calcium Substances 0.000 abstract 1
229910052791 calcium Inorganic materials 0.000 abstract 1
229940096919 glycogen Drugs 0.000 abstract 1
210000002175 goblet cell Anatomy 0.000 abstract 1
230000004054 inflammatory process Effects 0.000 abstract 1
239000011777 magnesium Substances 0.000 abstract 1
229910052749 magnesium Inorganic materials 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
210000003097 mucus Anatomy 0.000 abstract 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
239000010452 phosphate Substances 0.000 abstract 1
239000011591 potassium Substances 0.000 abstract 1
229910052700 potassium Inorganic materials 0.000 abstract 1
239000011734 sodium Substances 0.000 abstract 1
229910052708 sodium Inorganic materials 0.000 abstract 1
-1 tetracycline compound Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Ophthalmology & Optometry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Inorganic Chemistry (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT99937618T 1998-08-06 1999-07-29 Augenlösung mit tetracyclin für behandlung von trockenen augen ATE265856T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/130,638 US6432934B1 (en)	1998-08-06	1998-08-06	Methods and compositions for topical treatment of eye surface inflammation and related dry eye disease
PCT/US1999/017185 WO2000007601A1 (en)	1998-08-06	1999-07-29	Ophtalmic solution with tetracycline for topical treatment of dry eye disease

Publications (1)

Publication Number	Publication Date
ATE265856T1 true ATE265856T1 (de)	2004-05-15

Family

ID=22445630

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99937618T ATE265856T1 (de)	1998-08-06	1999-07-29	Augenlösung mit tetracyclin für behandlung von trockenen augen

Country Status (9)

Country	Link
US (1)	US6432934B1 (de)
EP (1)	EP1105139B1 (de)
JP (1)	JP2003523925A (de)
AT (1)	ATE265856T1 (de)
AU (1)	AU777744B2 (de)
CA (1)	CA2339792C (de)
DE (1)	DE69917040T2 (de)
ES (1)	ES2224686T3 (de)
WO (1)	WO2000007601A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6455583B1 (en) *	1998-05-08	2002-09-24	The University Of Miami	Method for treating meibomian gland disease
EP1829546A1 (de) *	1999-09-14	2007-09-05	Mucosal Therapeutics LLC	Formulierungen zur Behandlung oder Vorbeugung von Mucositis
EP1212050B1 (de) *	1999-09-14	2006-12-06	Mucosal Therapeutics LLC	Zusammensetzungen, welche tetracycline enthalten, zur behandlung oder verhinderung von mukositis
US6946118B1 (en)	1999-09-14	2005-09-20	Orapharma, Inc.	Formulations for treating or preventing mucositis
US7211267B2 (en)	2001-04-05	2007-05-01	Collagenex Pharmaceuticals, Inc.	Methods of treating acne
AU2002303250B2 (en) *	2001-04-05	2006-05-25	Collagenex Pharmaceuticals, Inc.	Methods of treating acne
US20030211043A1 (en) *	2001-09-28	2003-11-13	Korb Donald R.	Eye treatment
US8192749B2 (en)	2003-04-16	2012-06-05	Galderma Laboratories Inc.	Methods of simultaneously treating ocular rosacea and acne rosacea
EP1494681A4 (de)	2002-04-16	2008-08-06	Collagenex Pharm Inc	Verfahren zum gleichzeitigen behandeln von okularer rosacea und akne rosacea
US7875270B2 (en)	2002-09-17	2011-01-25	Abbott Medical Optics Inc.	Treatment solution and method for preventing posterior capsular opacification by selectively inducing detachment and/or death of lens epithelial cells
US7985405B2 (en) *	2002-09-17	2011-07-26	Jin Jun Zhang	Treatment solution and method for preventing posterior capsular opacification by selectively inducing detachment and/or death of lens epithelial cells
US8410102B2 (en)	2003-05-27	2013-04-02	Galderma Laboratories Inc.	Methods and compositions for treating or preventing erythema
US7439241B2 (en) *	2003-05-27	2008-10-21	Galderma Laboratories, Inc.	Compounds, formulations, and methods for treating or preventing rosacea
US6984628B2 (en) *	2003-07-15	2006-01-10	Allergan, Inc.	Ophthalmic compositions comprising trefoil factor family peptides
US8748402B2 (en)	2004-06-07	2014-06-10	Bausch & Lomb Pharma Holdings Corp.	Ophthalmic formulations and uses thereof
US8372814B2 (en)	2004-06-07	2013-02-12	Ista Pharmaceuticals, Inc.	Ophthalmic formulations and uses thereof
US20070207116A1 (en) *	2006-03-01	2007-09-06	Brown David C	Antioxidant compositions for the eye
WO2008085913A1 (en) *	2007-01-04	2008-07-17	Rib-X Pharmaceuticals, Inc.	Methods for treating, preventing, or reducing the risk of opthalmic, otic, and nasal infections
US20080188446A1 (en) *	2007-02-02	2008-08-07	Warner Chilcott Company Inc.	Tetracycline compositions for topical administration
WO2008097850A1 (en) *	2007-02-02	2008-08-14	Warner Chilcott Company, Inc.	Tretracycline compositions for topical administration
BRPI0808410A2 (pt) *	2007-02-28	2015-06-23	Aciex Therapeutics Inc	Métodos e composições para normalizar secreções da glândula meibomiana
EP2187900B1 (de) *	2007-08-16	2016-11-09	The Schepens Eye Research Institute, Inc.	Therapeutische zusammensetzungen zur behandlung von entzündungen von okular- und adnexgeweben
EP2329849B1 (de)	2009-11-18	2015-04-29	Galderma Research & Development	Kombination aus einem Alpha-2-Adrenozeptor-Agonisten und einem nichtsteroidalen entzündungshemmenden Mittel zur Behandlung oder Prävention einer Entzündungskrankheit der Haut
US8394800B2 (en) *	2009-11-19	2013-03-12	Galderma Laboratories, L.P.	Method for treating psoriasis
WO2011106697A1 (en) *	2010-02-25	2011-09-01	Schepens Eye Research Institute	Therapeutic compositions for the treatment of dry eye disease
CN106038476B (zh)	2010-03-26	2020-04-17	盖尔德马研究及发展公司	安全和有效治疗红斑的改进的方法和组合物
US8916562B2 (en)	2010-03-26	2014-12-23	Galderma Research & Development Snc	Methods and compositions for safe and effective treatment of telangiectasia
KR101799304B1 (ko)	2010-05-12	2017-11-20	렘펙스 파머수티클스 인코퍼레이티드	테트라사이클린 조성물
US8053427B1 (en)	2010-10-21	2011-11-08	Galderma R&D SNC	Brimonidine gel composition
EP2629757A2 (de)	2010-10-21	2013-08-28	Galderma S.A.	Brimonidin-gelzusammensetzungen und verwendungsverfahren
US20120190653A1 (en) *	2011-01-20	2012-07-26	Dow Pharmaceutical Sciences, Inc.	Therapeutic eye drop comprising doxycycline and a stabilizer
WO2013191167A1 (ja) *	2012-06-19	2013-12-27	参天製薬株式会社	ヘアレス動物の眼瞼状態の変化方法
PT106679B (pt) *	2012-11-27	2015-03-25	Hovione Farmaciencia Sa	Formulações tópicas de tetraciclinas, sua preparação e usos
PT108978B (pt) *	2015-11-24	2020-03-09	Hovione Farm S A	Sais de tetraciclinas
GB201705255D0 (en) *	2017-03-31	2017-05-17	Univ I Tromsø - Norges Arktiske Univ	Bioactive cyclic compounds
US12305185B2 (en)	2018-01-23	2025-05-20	Mount Spec Investments Pty Ltd	Expression vector and method

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1263606A (en) *	1985-05-29	1989-12-05	Jeffrey P. Gilbard	Non-toxic opthalmic preparations
IE74244B1 (en) *	1985-10-01	1997-07-16	Bimeda Res Dev Ltd	A process for preparing an antibiotic composition
JPS62240629A (ja)	1986-04-02	1987-10-21	Kao Corp	眼科用薬剤組成物
FR2660193B1 (fr) *	1990-04-03	1994-11-04	Philippe Maincent	Produit opthalmique comportant des nanocapsules, son procede de preparation et utilisation des nanocapsules.
US5789395A (en) *	1996-08-30	1998-08-04	The Research Foundation Of State University Of New York	Method of using tetracycline compounds for inhibition of endogenous nitric oxide production
US6455583B1 (en)	1998-05-08	2002-09-24	The University Of Miami	Method for treating meibomian gland disease

1998
- 1998-08-06 US US09/130,638 patent/US6432934B1/en not_active Expired - Fee Related
1999
- 1999-07-29 CA CA002339792A patent/CA2339792C/en not_active Expired - Fee Related
- 1999-07-29 JP JP2000563286A patent/JP2003523925A/ja active Pending
- 1999-07-29 ES ES99937618T patent/ES2224686T3/es not_active Expired - Lifetime
- 1999-07-29 AT AT99937618T patent/ATE265856T1/de active
- 1999-07-29 WO PCT/US1999/017185 patent/WO2000007601A1/en not_active Ceased
- 1999-07-29 AU AU52412/99A patent/AU777744B2/en not_active Ceased
- 1999-07-29 DE DE69917040T patent/DE69917040T2/de not_active Expired - Lifetime
- 1999-07-29 EP EP99937618A patent/EP1105139B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
WO2000007601A1 (en)	2000-02-17
EP1105139A1 (de)	2001-06-13
DE69917040T2 (de)	2005-04-28
JP2003523925A (ja)	2003-08-12
EP1105139B1 (de)	2004-05-06
DE69917040D1 (de)	2004-06-09
AU777744B2 (en)	2004-10-28
AU5241299A (en)	2000-02-28
ES2224686T3 (es)	2005-03-01
US6432934B1 (en)	2002-08-13
CA2339792A1 (en)	2000-02-17
CA2339792C (en)	2009-03-31

Legal Events

Date

Code

Title

Description

2005-07-15

UEP

Publication of translation of european patent specification

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Publication	Publication Date	Title
ATE265856T1 (de)	2004-05-15	Augenlösung mit tetracyclin für behandlung von trockenen augen
CA2154533A1 (en)	1996-01-26	Opthalmic preparation for use as artificial tear
ATE68700T1 (de)	1991-11-15	Nichttoxische ophthalmische zubereitungen und verfahren zu ihrer herstellung.
YU46899A (sh)	2000-10-30	Kontrolisano oslobadjanje farmaceutika u prednjoj komori oka
ATE205723T1 (de)	2001-10-15	Applikation von sod in liposomen
AR035509A1 (es)	2004-06-02	Solucion de lagrimas artificiales mejorada que contiene una combinacion de tres emolientes y el uso de dicha solucion para la fabricacion de un medicamento
NZ505742A (en)	2002-11-26	Compositions containing aminobiguanides with antimicrobial activity used to treat contact lenses
ATE202557T1 (de)	2001-07-15	15-fluoro-prostaglandine als augendrucksenkende mittel
EP0381617A3 (de)	1992-03-04	Desinfektions- und Reinigungsmittel für Kontaktlinsen
KR900002789A (ko)	1990-03-23	안과용 용액을 보존하는 방법 및 이를 위한 조성물
KR100354606B1 (ko)	2002-09-30	다목적 콘택트 렌즈 관리 용액 조성물
ATE272389T1 (de)	2004-08-15	Verwendung einer lacrophyl zubereitung in augentropfen, die therapeutisch wirksame komponenten enthalten
WO2001047576A3 (en)	2002-02-28	Compositions for replacement fluid and associated systems and methods usable in the performance of frequent hemofiltration
DE60205913D1 (de)	2005-10-06	Ophthalmische zubereitung mit n-acetylcystein zur behandlung trockener augen
RU93010275A (ru)	1995-09-10	Глазные капли "кератоник"
DK0875248T3 (da)	2003-06-10	Anvendelse af hyaluronsyre og korresponderende salte til fremstilling af en vandig opløsning, der er velegnet som intra-artikulær skyllevæske
CA2585266A1 (en)	2006-05-04	Ophthalmic compositions and methods of using the same
DE60000736D1 (de)	2002-12-12	Miotische wirkstoffe und hypertonische wirkstoffe enthaltende ophthalmische zusammensetzungen
WO1991017469A1 (en)	1991-11-14	Kit for contact lenses
DE69127619D1 (de)	1997-10-16	Ketanserin enthaltende Augentropfen zur Behandlung von intraokularem Druck
JPS5780311A (en)	1982-05-19	Foaming lubricant for massage
DE69914066T2 (de)	2004-10-21	Augenspüllösung
RU2000113137A (ru)	2002-05-20	Способ регулируемого биоокислительного некролиза и детоксикации при тяжелых ожогах и бактериальных язвах роговицы
JP2000281563A (ja)	2000-10-10	眼科用液剤
RU2000128330A (ru)	2002-09-20	Способ повышения зрительных функций после хирургического лечения отслойки сетчатки