ATE266663T1 - Acrylamid-derivate und verfahren zu deren herstellung - Google Patents

Acrylamid-derivate und verfahren zu deren herstellung

Info

Publication number: ATE266663T1
Authority: AT; Austria
Prior art keywords: acrylamide derivatives; general formula; production; derivatives represented; eüindole
Prior art date: 1994-11-29

Application number

AT95937194T

Other languages

English (en)

Inventor

Yasumichi Fukuda

Shigeki Seto

Yasuo Oomori

Hiroyuki Ebisu

Shiro Terashima

Original Assignee

Kyorin Seiyaku Kk

Sagami Chem Res

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-11-29

Filing date

1995-11-28

Publication date

2004-05-15

1995-11-28 Application filed by Kyorin Seiyaku Kk, Sagami Chem Res filed Critical Kyorin Seiyaku Kk

2004-05-15 Application granted granted Critical

2004-05-15 Publication of ATE266663T1 publication Critical patent/ATE266663T1/de

Links

HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical class NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 title 1
206010028980 Neoplasm Diseases 0.000 abstract 2
150000003926 acrylamides Chemical class 0.000 abstract 2
201000011510 cancer Diseases 0.000 abstract 1
231100001231 less toxic Toxicity 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Indole Compounds (AREA)
Fertilizers (AREA)

AT95937194T 1994-11-29 1995-11-28 Acrylamid-derivate und verfahren zu deren herstellung ATE266663T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP29527494		1994-11-29
PCT/JP1995/002413 WO1996016965A1 (en)	1994-11-29	1995-11-28	Acrylamide derivatives and process for producing the same

Publications (1)

Publication Number	Publication Date
ATE266663T1 true ATE266663T1 (de)	2004-05-15

Family

ID=17818480

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95937194T ATE266663T1 (de)	1994-11-29	1995-11-28	Acrylamid-derivate und verfahren zu deren herstellung

Country Status (12)

Country	Link
US (1)	US5786486A (de)
EP (1)	EP0799827B1 (de)
KR (1)	KR100395083B1 (de)
CN (1)	CN1051552C (de)
AT (1)	ATE266663T1 (de)
AU (1)	AU693283B2 (de)
CA (1)	CA2205872A1 (de)
DE (1)	DE69533043T2 (de)
FI (1)	FI972074A0 (de)
HU (1)	HUT77654A (de)
MX (1)	MX9703917A (de)
WO (1)	WO1996016965A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ID24959A (id)	1998-01-28	2000-08-31	Shionogi & Co	Senyawa-senyawa trisiklik yang baru
US6989452B2 (en) *	2001-05-31	2006-01-24	Medarex, Inc.	Disulfide prodrugs and linkers and stabilizers useful therefor
US7691962B2 (en) *	2004-05-19	2010-04-06	Medarex, Inc.	Chemical linkers and conjugates thereof
JP4806680B2 (ja) *	2004-05-19	2011-11-02	メダレックスインコーポレイテッド	自己犠牲リンカー及び薬剤複合体
JP2008529556A (ja) *	2005-02-18	2008-08-07	メダレックス，インク．	前立腺特異的膜抗原（ｐｓｍａ）に対するヒトモノクローナル抗体
US7714016B2 (en) *	2005-04-08	2010-05-11	Medarex, Inc.	Cytotoxic compounds and conjugates with cleavable substrates
RS52100B (sr)	2005-10-26	2012-06-30	Medarex, Inc.	Postupci i jedinjenja za pripremu analoga cc-1065
WO2007059404A2 (en)	2005-11-10	2007-05-24	Medarex, Inc.	Duocarmycin derivatives as novel cytotoxic compounds and conjugates
TWI412367B (zh)	2006-12-28	2013-10-21	梅達雷克斯有限責任公司	化學鏈接劑與可裂解基質以及其之綴合物
AR065404A1 (es)	2007-02-21	2009-06-03	Medarex Inc	Conjugados farmaco-ligando, los que se unen a citotoxinas potentes, composicion farmaceutica que los contienen y su uso para retardar o detener el crecimiento de un tumor en un mamifero
CA2891280C (en)	2012-11-24	2018-03-20	Hangzhou Dac Biotech Co., Ltd.	Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
US10464955B2 (en)	2014-02-28	2019-11-05	Hangzhou Dac Biotech Co., Ltd.	Charged linkers and their uses for conjugation
NZ739830A (en)	2015-07-12	2021-12-24	Hangzhou Dac Biotech Co Ltd	Bridge linkers for conjugation of cell-binding molecules
US9839687B2 (en)	2015-07-15	2017-12-12	Suzhou M-Conj Biotech Co., Ltd.	Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
KR20220150408A (ko)	2016-11-14	2022-11-10	항저우 디에이씨 바이오테크 씨오, 엘티디	결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
EP4426727A2 (de)	2021-11-03	2024-09-11	Hangzhou Dac Biotech Co., Ltd.	Spezifische konjugation eines antikörpers
CN118725371B (zh) *	2024-07-12	2025-10-03	华南农业大学	一种基于肉桂醛衍生物的高效抗菌水凝胶包装膜及其制备方法和在冷鲜肉保鲜中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1238907A (en) *	1984-02-21	1988-07-05	Robert C. Kelly	1,2,8,8a-tetrahydrocyclopropa¬c\|pyrrolo(3,2-e)- indol-4(5h)-ones and related compounds
DE3750612T2 (de) *	1986-12-19	1995-03-02	Upjohn Co	Cc-1065 analoge.
US5258383A (en) *	1991-06-28	1993-11-02	Kyowa Hakko Kogyo Co., Ltd.	DC-89 derivatives
JP2502005B2 (ja)	1992-04-27	1996-05-29	オンキヨー株式会社	バイオフィ―ドバックシステム
JP3514490B2 (ja) *	1992-08-21	2004-03-31	杏林製薬株式会社	トリフルオロメチルピロロインドールカルボン酸エステル誘導体及びその製造方法

1995
- 1995-11-28 CN CN95197472A patent/CN1051552C/zh not_active Expired - Fee Related
- 1995-11-28 KR KR1019970703468A patent/KR100395083B1/ko not_active Expired - Fee Related
- 1995-11-28 WO PCT/JP1995/002413 patent/WO1996016965A1/ja not_active Ceased
- 1995-11-28 DE DE69533043T patent/DE69533043T2/de not_active Expired - Fee Related
- 1995-11-28 US US08/849,160 patent/US5786486A/en not_active Expired - Fee Related
- 1995-11-28 AU AU39370/95A patent/AU693283B2/en not_active Ceased
- 1995-11-28 CA CA002205872A patent/CA2205872A1/en not_active Abandoned
- 1995-11-28 EP EP95937194A patent/EP0799827B1/de not_active Expired - Lifetime
- 1995-11-28 AT AT95937194T patent/ATE266663T1/de not_active IP Right Cessation
- 1995-11-28 MX MX9703917A patent/MX9703917A/es not_active IP Right Cessation
- 1995-11-28 HU HU9800067A patent/HUT77654A/hu not_active Application Discontinuation
1997
- 1997-05-14 FI FI972074A patent/FI972074A0/fi not_active Application Discontinuation

Also Published As

Publication number	Publication date
KR100395083B1 (ko)	2004-02-05
DE69533043T2 (de)	2005-04-07
AU3937095A (en)	1996-06-19
CA2205872A1 (en)	1996-06-06
CN1174553A (zh)	1998-02-25
MX9703917A (es)	1998-05-31
FI972074A0 (fi)	1997-05-14
DE69533043D1 (de)	2004-06-17
HUT77654A (hu)	1998-07-28
WO1996016965A1 (en)	1996-06-06
EP0799827A4 (de)	1998-01-28
EP0799827A1 (de)	1997-10-08
AU693283B2 (en)	1998-06-25
CN1051552C (zh)	2000-04-19
US5786486A (en)	1998-07-28
EP0799827B1 (de)	2004-05-12

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Legal Events

Date	Code	Title	Description
2004-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties