ATE266663T1 - Acrylamid-derivate und verfahren zu deren herstellung - Google Patents

Acrylamid-derivate und verfahren zu deren herstellung

Info

Publication number: ATE266663T1
Authority: AT; Austria
Prior art keywords: acrylamide derivatives; general formula; production; derivatives represented; eüindole
Prior art date: 1994-11-29

Application number

AT95937194T

Other languages

English (en)

Inventor

Yasumichi Fukuda

Shigeki Seto

Yasuo Oomori

Hiroyuki Ebisu

Shiro Terashima

Original Assignee

Kyorin Seiyaku Kk

Sagami Chem Res

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-11-29

Filing date

1995-11-28

Publication date

2004-05-15

1995-11-28 Application filed by Kyorin Seiyaku Kk, Sagami Chem Res filed Critical Kyorin Seiyaku Kk

2004-05-15 Application granted granted Critical

2004-05-15 Publication of ATE266663T1 publication Critical patent/ATE266663T1/de

Links

HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical class NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 title 1
206010028980 Neoplasm Diseases 0.000 abstract 2
150000003926 acrylamides Chemical class 0.000 abstract 2
201000011510 cancer Diseases 0.000 abstract 1
231100001231 less toxic Toxicity 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Indole Compounds (AREA)
Fertilizers (AREA)

AT95937194T 1994-11-29 1995-11-28 Acrylamid-derivate und verfahren zu deren herstellung ATE266663T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP29527494		1994-11-29
PCT/JP1995/002413 WO1996016965A1 (en)	1994-11-29	1995-11-28	Acrylamide derivatives and process for producing the same

Publications (1)

Publication Number	Publication Date
ATE266663T1 true ATE266663T1 (de)	2004-05-15

Family

ID=17818480

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95937194T ATE266663T1 (de)	1994-11-29	1995-11-28	Acrylamid-derivate und verfahren zu deren herstellung

Country Status (12)

Country	Link
US (1)	US5786486A (de)
EP (1)	EP0799827B1 (de)
KR (1)	KR100395083B1 (de)
CN (1)	CN1051552C (de)
AT (1)	ATE266663T1 (de)
AU (1)	AU693283B2 (de)
CA (1)	CA2205872A1 (de)
DE (1)	DE69533043T2 (de)
FI (1)	FI972074A0 (de)
HU (1)	HUT77654A (de)
MX (1)	MX9703917A (de)
WO (1)	WO1996016965A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL341984A1 (en) *	1998-01-28	2001-05-07	Shionogi & Co	Novel tricycle compounds
KR20030033007A (ko) *	2001-05-31	2003-04-26	코울터 파머수티컬, 인코포레이티드	세포독소, 약물전구체, 링커 및 이에 유용한 안정화제
US7691962B2 (en) *	2004-05-19	2010-04-06	Medarex, Inc.	Chemical linkers and conjugates thereof
BRPI0510909A2 (pt) *	2004-05-19	2008-12-16	Medarex Inc	composto de ligaÇço fÁrmaco-ligante citotàxico, formulaÇço farmacÊutica, mÉtodo para matar uma cÉlula e mÉtodo para retardar ou interromper o crescimento de tumor
ES2386366T3 (es) *	2005-02-18	2012-08-17	Medarex, Inc.	Anticuerpo monoclonal humano contra el antígeno de membrana específico de la próstata (PSMA)
US7714016B2 (en) *	2005-04-08	2010-05-11	Medarex, Inc.	Cytotoxic compounds and conjugates with cleavable substrates
BRPI0619331A2 (pt)	2005-10-26	2011-09-27	Medarex Inc	método para fazer um composto para preparar um análogo de cbi cc-1065, método para preparar um análogo de cbi cc-1065 e composto
WO2007059404A2 (en)	2005-11-10	2007-05-24	Medarex, Inc.	Duocarmycin derivatives as novel cytotoxic compounds and conjugates
TWI412367B (zh)	2006-12-28	2013-10-21	梅達雷克斯有限責任公司	化學鏈接劑與可裂解基質以及其之綴合物
JP2010519310A (ja)	2007-02-21	2010-06-03	メダレックスインコーポレイテッド	単一のアミノ酸を有する化学リンカーおよびその複合体
US10131682B2 (en)	2012-11-24	2018-11-20	Hangzhou Dac Biotech Co., Ltd.	Hydrophilic linkers and their uses for conjugation of drugs to a cell binding molecules
JP6417421B2 (ja)	2014-02-28	2018-11-07	ハンジョウディーエーシーバイオテックシーオー．，エルティディ．ＨａｎｇｚｈｏｕＤａｃＢｉｏｔｅｃｈＣｏ．，Ｌｔｄ．	荷電連結体及び共役体のためのその使用
CA2991973C (en)	2015-07-12	2021-12-07	Suzhou M-Conj Biotech Co., Ltd.	Bridge linkers for conjugation of a cell-binding molecule
US9839687B2 (en)	2015-07-15	2017-12-12	Suzhou M-Conj Biotech Co., Ltd.	Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
KR20220147719A (ko)	2016-11-14	2022-11-03	항저우 디에이씨 바이오테크 씨오, 엘티디	결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
CN117980327A (zh)	2021-11-03	2024-05-03	杭州多禧生物科技有限公司	抗体的特异性偶联
CN118725371B (zh) *	2024-07-12	2025-10-03	华南农业大学	一种基于肉桂醛衍生物的高效抗菌水凝胶包装膜及其制备方法和在冷鲜肉保鲜中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1238907A (en) *	1984-02-21	1988-07-05	Robert C. Kelly	1,2,8,8a-tetrahydrocyclopropa¬c\|pyrrolo(3,2-e)- indol-4(5h)-ones and related compounds
AU617304B2 (en) *	1986-12-19	1991-11-28	Pharmacia & Upjohn Company	Novel cc-1065 analogs
EP0520435A3 (en) *	1991-06-28	1993-05-05	Kyowa Hakko Kogyo Co., Ltd.	Dc-89 derivatives
JP2502005B2 (ja)	1992-04-27	1996-05-29	オンキヨー株式会社	バイオフィ―ドバックシステム
JP3514490B2 (ja) *	1992-08-21	2004-03-31	杏林製薬株式会社	トリフルオロメチルピロロインドールカルボン酸エステル誘導体及びその製造方法

1995
- 1995-11-28 AT AT95937194T patent/ATE266663T1/de not_active IP Right Cessation
- 1995-11-28 MX MX9703917A patent/MX9703917A/es not_active IP Right Cessation
- 1995-11-28 CN CN95197472A patent/CN1051552C/zh not_active Expired - Fee Related
- 1995-11-28 US US08/849,160 patent/US5786486A/en not_active Expired - Fee Related
- 1995-11-28 AU AU39370/95A patent/AU693283B2/en not_active Ceased
- 1995-11-28 HU HU9800067A patent/HUT77654A/hu not_active Application Discontinuation
- 1995-11-28 WO PCT/JP1995/002413 patent/WO1996016965A1/ja not_active Ceased
- 1995-11-28 EP EP95937194A patent/EP0799827B1/de not_active Expired - Lifetime
- 1995-11-28 DE DE69533043T patent/DE69533043T2/de not_active Expired - Fee Related
- 1995-11-28 KR KR1019970703468A patent/KR100395083B1/ko not_active Expired - Fee Related
- 1995-11-28 CA CA002205872A patent/CA2205872A1/en not_active Abandoned
1997
- 1997-05-14 FI FI972074A patent/FI972074A0/fi not_active Application Discontinuation

Also Published As

Publication number	Publication date
KR100395083B1 (ko)	2004-02-05
CA2205872A1 (en)	1996-06-06
CN1051552C (zh)	2000-04-19
DE69533043T2 (de)	2005-04-07
US5786486A (en)	1998-07-28
EP0799827B1 (de)	2004-05-12
EP0799827A1 (de)	1997-10-08
MX9703917A (es)	1998-05-31
AU3937095A (en)	1996-06-19
AU693283B2 (en)	1998-06-25
DE69533043D1 (de)	2004-06-17
FI972074A0 (fi)	1997-05-14
WO1996016965A1 (en)	1996-06-06
EP0799827A4 (de)	1998-01-28
HUT77654A (hu)	1998-07-28
CN1174553A (zh)	1998-02-25

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Legal Events

Date	Code	Title	Description
2004-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties