ATE26703T1 - (alpha-(alkylaminomethyl)-benzylthio>-essigsaeur - derivate, verfahren zur herstellung und verwendung in therapie. - Google Patents

(alpha-(alkylaminomethyl)-benzylthio>-essigsaeur - derivate, verfahren zur herstellung und verwendung in therapie.

Info

Publication number: ATE26703T1
Authority: AT; Austria
Prior art keywords: formula; benzylthio; alkyl; alkylaminomethyl; alpha
Prior art date: 1984-03-23

Application number

AT85400431T

Other languages

English (en)

Inventor

Louis Lafon

Original Assignee

Lafon Labor

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-03-23

Filing date

1985-03-06

Publication date

1987-05-15

1985-03-06 Application filed by Lafon Labor filed Critical Lafon Labor

1987-05-15 Application granted granted Critical

1987-05-15 Publication of ATE26703T1 publication Critical patent/ATE26703T1/de

Links

238000000034 method Methods 0.000 title abstract 3
238000004519 manufacturing process Methods 0.000 title 1
238000002560 therapeutic procedure Methods 0.000 title 1
-1 amine derivative of (benzylthio)acetic acid Chemical class 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
230000003287 optical effect Effects 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical compound C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 abstract 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
239000002184 metal Substances 0.000 abstract 1
238000007254 oxidation reaction Methods 0.000 abstract 1
239000012429 reaction media Substances 0.000 abstract 1
238000010992 reflux Methods 0.000 abstract 1
229940071127 thioglycolate Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/265—Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Emergency Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT85400431T 1984-03-23 1985-03-06 (alpha-(alkylaminomethyl)-benzylthio>-essigsaeur - derivate, verfahren zur herstellung und verwendung in therapie. ATE26703T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8404543A FR2561646B1 (fr)	1984-03-23	1984-03-23	Derives d'acide (a-(alkylaminomethyl)-benzyl)-thioacetique, procede de preparation et utilisation en therapeutique
EP85400431A EP0158545B1 (de)	1984-03-23	1985-03-06	[Alpha-(Alkylaminomethyl)-Benzylthio]-essigsäure-Derivate, Verfahren zur Herstellung und Verwendung in Therapie

Publications (1)

Publication Number	Publication Date
ATE26703T1 true ATE26703T1 (de)	1987-05-15

Family

ID=9302390

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT85400431T ATE26703T1 (de)	1984-03-23	1985-03-06	(alpha-(alkylaminomethyl)-benzylthio>-essigsaeur - derivate, verfahren zur herstellung und verwendung in therapie.

Country Status (4)

Country	Link
EP (1)	EP0158545B1 (de)
AT (1)	ATE26703T1 (de)
DE (1)	DE3560141D1 (de)
FR (1)	FR2561646B1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2648814B1 (fr) *	1989-06-26	1991-10-18	Lafon Labor	L'alpha (tert-butyl-aminomethyl-3,4-dichlorobenzyl)thioacetamide, son procede de preparation et son application en therapeutique
FR2734264B1 (fr) *	1995-05-19	1997-08-01	Lafon Labor	Utilisation de derives d'alpha-aminomethyl-3,4-dichlorobenzyl-thioacetamide pour la fabrication d'un medicament inhibant la recapture de la dopamine et nouveaux composes pour cette utilisation
EE04295B1 (et) *	1997-02-27	2004-06-15	American Cyanamid Company	N-hüdroksü-2-(alküül-, arüül- või heteroarüülsulfanüül-, -sulfinüül- või-sulfonüül-)-3-asendatud-alküülamiidid, -arüülamiidid või -heteroarüülamiididkui maatriksmetalloproteinaasi inhibiitorid
US6172057B1 (en)	1997-02-27	2001-01-09	American Cyanamid Company	N-Hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1520812A (en) *	1975-10-02	1978-08-09	Lafon Labor	Benzhydrylsulphinyl derivatives
GB1584462A (en) *	1977-03-31	1981-02-11	Lafon Labor	N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them

1984
- 1984-03-23 FR FR8404543A patent/FR2561646B1/fr not_active Expired
1985
- 1985-03-06 DE DE8585400431T patent/DE3560141D1/de not_active Expired
- 1985-03-06 EP EP85400431A patent/EP0158545B1/de not_active Expired
- 1985-03-06 AT AT85400431T patent/ATE26703T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
FR2561646B1 (fr)	1987-10-09
EP0158545B1 (de)	1987-04-22
FR2561646A1 (fr)	1985-09-27
EP0158545A1 (de)	1985-10-16
DE3560141D1 (en)	1987-05-27

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Legal Events

Date	Code	Title	Description
1987-08-15	UEP	Publication of translation of european patent specification
2004-12-15	REN	Ceased due to non-payment of the annual fee