ATE268322T1 - Inhibitoren der tryptase - Google Patents

Inhibitoren der tryptase

Info

Publication number
ATE268322T1
ATE268322T1 AT00990777T AT00990777T ATE268322T1 AT E268322 T1 ATE268322 T1 AT E268322T1 AT 00990777 T AT00990777 T AT 00990777T AT 00990777 T AT00990777 T AT 00990777T AT E268322 T1 ATE268322 T1 AT E268322T1
Authority
AT
Austria
Prior art keywords
inhibitors
tryptase
meanings
compounds
indicated
Prior art date
Application number
AT00990777T
Other languages
English (en)
Inventor
Thomas Baer
Josef Stadlwieser
Wolf-Ruediger Ulrich
Andreas Dominik
Daniela Bundschuh
Karl Zech
Christian Sommerhoff
Thomas Martin
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of ATE268322T1 publication Critical patent/ATE268322T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT00990777T 1999-12-20 2000-12-16 Inhibitoren der tryptase ATE268322T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99125382 1999-12-20
PCT/EP2000/012840 WO2001046128A2 (en) 1999-12-20 2000-12-16 Tryptase inhibitors

Publications (1)

Publication Number Publication Date
ATE268322T1 true ATE268322T1 (de) 2004-06-15

Family

ID=8239660

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00990777T ATE268322T1 (de) 1999-12-20 2000-12-16 Inhibitoren der tryptase

Country Status (13)

Country Link
US (1) US6815557B2 (de)
EP (1) EP1244614B1 (de)
JP (1) JP2003518087A (de)
AT (1) ATE268322T1 (de)
AU (1) AU783371B2 (de)
CA (1) CA2392127A1 (de)
DE (1) DE60011300T2 (de)
DK (1) DK1244614T3 (de)
ES (1) ES2222270T3 (de)
PT (1) PT1244614E (de)
SI (1) SI1244614T1 (de)
TR (1) TR200402164T4 (de)
WO (1) WO2001046128A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2225758T3 (es) 2001-01-31 2005-03-16 Altana Pharma Ag Derivdos de diazocina y su uso como agentes inhibidores de la triptasa.
JP2004518735A (ja) 2001-02-21 2004-06-24 アルタナ　ファルマ　アクチエンゲゼルシャフト トリプターゼインヒビター
EP1368317B1 (de) 2001-02-21 2006-12-27 Altana Pharma AG Tryptaseinhibitoren
AU2002254941B2 (en) * 2001-03-15 2007-05-17 Altana Pharma Ag Tryptase-inhibitors
WO2002074732A2 (en) * 2001-03-15 2002-09-26 Altana Pharma Ag Tryptase-inhibitors
CA2450659A1 (en) 2001-06-19 2002-12-27 Altana Pharma Ag Tryptase inhibitors
GB0507577D0 (en) * 2005-04-14 2005-05-18 Novartis Ag Organic compounds

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3999946A (en) * 1976-02-23 1976-12-28 Allied Chemical Corporation Time-temperature history indicators
US4228126A (en) * 1977-11-25 1980-10-14 Allied Chemical Corporation Diacetylene time-temperature indicators
AU2764495A (en) * 1994-06-01 1995-12-21 Arris Pharmaceutical Corporation Compositions and methods for treating mast-cell mediated conditions
PL183552B1 (pl) 1994-09-23 2002-06-28 Axys Pharmaceuticals Nowe związki cykliczne i środek farmaceutyczny
EE9900036A (et) 1996-07-30 1999-08-16 Arris Pharmaceutical Corporation Uued ühendid ja kompositsioonid trüptaasi aktiivsusega seotud haiguste raviks
WO1999012918A1 (en) 1997-09-05 1999-03-18 Yoshitomi Pharmaceutical Industries, Ltd. Tryptase inhibitor
AU1208999A (en) 1997-11-10 1999-05-31 Array Biopharma, Inc. Compounds which inhibit tryptase activity
US6221914B1 (en) 1997-11-10 2001-04-24 Array Biopharma Inc. Sulfonamide bridging compounds that inhibit tryptase activity
EP1060171A2 (de) * 1998-02-06 2000-12-20 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Tryptase-inhibitoren
US6489327B1 (en) 1998-02-06 2002-12-03 Max-Planck-Gesellschaft Zur Fordrungder Wisenschaften, E.V. Tryptase inhibitors
EP1115731A2 (de) 1998-09-04 2001-07-18 Byk Gulden Lomberg Chemische Fabrik GmbH Neue pyranosen
KR20020016942A (ko) 1999-08-10 2002-03-06 빅 굴덴 롬베르크 케미쉐 파브릭 게엠베하 디아조신-디온 유도체 및 이것의 트립타제 억제제로서 용도
AU778965B2 (en) 1999-09-14 2004-12-23 Altana Pharma Ag Tryptase inhibitors

Also Published As

Publication number Publication date
JP2003518087A (ja) 2003-06-03
DE60011300D1 (de) 2004-07-08
CA2392127A1 (en) 2001-06-28
TR200402164T4 (tr) 2004-10-21
US20030073720A1 (en) 2003-04-17
US6815557B2 (en) 2004-11-09
SI1244614T1 (en) 2004-10-31
EP1244614B1 (de) 2004-06-02
AU3013101A (en) 2001-07-03
AU783371B2 (en) 2005-10-20
ES2222270T3 (es) 2005-02-01
DE60011300T2 (de) 2005-08-04
WO2001046128A3 (en) 2001-11-22
DK1244614T3 (da) 2004-09-27
EP1244614A2 (de) 2002-10-02
PT1244614E (pt) 2004-10-29
WO2001046128A2 (en) 2001-06-28

Similar Documents

Publication Publication Date Title
ES2186874T3 (es) Analogos de m-amidinofenilo como inhibidores del factor xa.
DE60310576D1 (en) 2-hydroxy-6-phenylphenanthridine als pde-4-hemmer
PL372926A1 (en) Piperidine-pyridazones and phthalazones as pde4 inhibitors
DK1070056T3 (da) Phthalazinon-PDE III/IV-inhibitorer
PT1140944E (pt) Derivados de epotilona e sua utilizacao como agentes antitumorais
TR200201128T2 (tr) PDE4 inhibitörleri olarak tetrahidrotiyopiranfitalazinon türevleri.
SE9903290D0 (sv) Novel compounds
DK1377574T3 (da) 6-phenylbenzonaphtyridiner
DK1244643T3 (da) Tryptaseinhibitorer
DK1204659T3 (da) Serotonerge benzofuraner
DE60316128D1 (de) N-sulfonylurea-apoptosis-förderer
BRPI0415285A (pt) derivados de aminoalcanol
ATE268322T1 (de) Inhibitoren der tryptase
ATE348803T1 (de) Tryptase-inhibitoren
ATE364037T1 (de) Tryptasehemmer
ATE491709T1 (de) Pyrrolidinohydrochinazoline
ATE328883T1 (de) Imidazopyridin-8-one
DK1358182T3 (da) Diazocin-derivater og anvendelsen deraf som tryptase-inhibitorer
ATE349427T1 (de) Tryptaseinhibitoren
AU758194C (en) Novel benzimidazoles and benzoxazoles
SG145571A1 (en) Intermediates useful in the synthesis of hiv-protease inhibitors and methods for preparing the same

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1244614

Country of ref document: EP

REN Ceased due to non-payment of the annual fee