ATE270298T1 - Reaktionssystem und verfahren zur verstärkung der lumineszenz von makrocyclischen lanthanid(iii)- komplexen - Google Patents

Reaktionssystem und verfahren zur verstärkung der lumineszenz von makrocyclischen lanthanid(iii)- komplexen

Info

Publication number: ATE270298T1
Authority: AT; Austria
Prior art keywords: luminescence; enhancing; lanthanide element; energy transfer; lanthanide
Prior art date: 1999-01-19

Application number

AT00905653T

Other languages

English (en)

Inventor

Robert C Leif

Lidia M Vallarino

Original Assignee

Robert C Leif

Lidia M Vallarino

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-19

Filing date

2000-01-18

Publication date

2004-07-15

2000-01-18 Application filed by Robert C Leif, Lidia M Vallarino filed Critical Robert C Leif

2004-07-15 Application granted granted Critical

2004-07-15 Publication of ATE270298T1 publication Critical patent/ATE270298T1/de

Links

229910052747 lanthanoid Inorganic materials 0.000 title abstract 6
150000002602 lanthanoids Chemical class 0.000 title abstract 6
238000004020 luminiscence type Methods 0.000 title abstract 5
230000002708 enhancing effect Effects 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
-1 macrocycle compound Chemical class 0.000 abstract 4
239000000203 mixture Substances 0.000 abstract 3
229910052693 Europium Inorganic materials 0.000 abstract 2
229910052772 Samarium Inorganic materials 0.000 abstract 2
229910052771 Terbium Inorganic materials 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
238000001514 detection method Methods 0.000 abstract 2
OGPBJKLSAFTDLK-UHFFFAOYSA-N europium atom Chemical compound [Eu] OGPBJKLSAFTDLK-UHFFFAOYSA-N 0.000 abstract 2
KZUNJOHGWZRPMI-UHFFFAOYSA-N samarium atom Chemical compound [Sm] KZUNJOHGWZRPMI-UHFFFAOYSA-N 0.000 abstract 2
238000000295 emission spectrum Methods 0.000 abstract 1
RJOJUSXNYCILHH-UHFFFAOYSA-N gadolinium(3+) Chemical compound [Gd+3] RJOJUSXNYCILHH-UHFFFAOYSA-N 0.000 abstract 1
150000002678 macrocyclic compounds Chemical class 0.000 abstract 1
239000000693 micelle Substances 0.000 abstract 1
239000004094 surface-active agent Substances 0.000 abstract 1
229910052727 yttrium Inorganic materials 0.000 abstract 1
VWQVUPCCIRVNHF-UHFFFAOYSA-N yttrium atom Chemical compound [Y] VWQVUPCCIRVNHF-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
- G01N2474/20—Immunohistochemistry assay
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Food Science & Technology (AREA)
General Health & Medical Sciences (AREA)
Cell Biology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
Microbiology (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Biotechnology (AREA)
Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Investigating Or Analysing Biological Materials (AREA)
Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Luminescent Compositions (AREA)

AT00905653T 1999-01-19 2000-01-18 Reaktionssystem und verfahren zur verstärkung der lumineszenz von makrocyclischen lanthanid(iii)- komplexen ATE270298T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US11631699P	1999-01-19	1999-01-19
PCT/US2000/001211 WO2000042048A1 (en)	1999-01-19	2000-01-18	A reagent system and method for increasing the luminescence of lanthanide(iii) macrocyclic complexes

Publications (1)

Publication Number	Publication Date
ATE270298T1 true ATE270298T1 (de)	2004-07-15

Family

ID=22366470

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00905653T ATE270298T1 (de)	1999-01-19	2000-01-18	Reaktionssystem und verfahren zur verstärkung der lumineszenz von makrocyclischen lanthanid(iii)- komplexen

Country Status (6)

Country	Link
US (2)	US6340744B1 (de)
EP (1)	EP1150985B1 (de)
AT (1)	ATE270298T1 (de)
CA (1)	CA2360054A1 (de)
DE (1)	DE60011877D1 (de)
WO (1)	WO2000042048A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7569342B2 (en)	1997-12-10	2009-08-04	Sierra Molecular Corp.	Removal of molecular assay interferences
US6340744B1 (en) *	1999-01-19	2002-01-22	Robert C. Leif	Reagent system and method for increasing the luminescence of lanthanide(III) macrocyclic complexes
GB0008618D0 (en) *	2000-04-08	2000-05-31	Univ Strathclyde	Analyte detection & apparatus therefor
US20060034954A1 (en) *	2001-02-02	2006-02-16	Bland Jeffrey S	Medical composition for balancing bodily processes
WO2003003063A2 (en) *	2001-06-28	2003-01-09	Ia, Inc.	Fiber-optic sensor array
EP1684808B1 (de) *	2003-11-07	2013-01-09	Newport Instruments	Reagenzsystem und verfahren zur modifizierung der lumineszenz von lanthanid(iii) makrozyklischen komplexen
US7955859B2 (en) *	2005-08-31	2011-06-07	Japan Science And Technology Agency	Fluorescent labeling compound
US8187573B2 (en) *	2005-10-21	2012-05-29	Immunochemistry Technologies, Llc	In vivo detection of apoptosis
GB0613823D0 (en) *	2006-07-12	2006-08-23	Univ Durham	Assay
KR100993389B1 (ko) *	2006-10-11	2010-11-09	주식회사 엘지화학	나노입자가 표면에 부착된 유기-무기 혼성 재료 및 그제조방법
WO2008058004A2 (en)	2006-11-02	2008-05-15	Winnik Mitchell A	Particles containing detectable elemental code
RU2369466C1 (ru) *	2008-02-26	2009-10-10	Государственное образовательное учреждение высшего профессионального образования "Курский государственный университет"	Способ получения наночастиц металлов или гибридов наночастиц металлов
SG177613A1 (en)	2009-07-10	2012-03-29	Linzy O Scott Iii	Methods and compositions for treating thyroid-related medical conditions with reduced folates
AU2011230619C1 (en)	2010-03-25	2016-06-23	Oregon Health & Science University	CMV glycoproteins and recombinant vectors
HUE037408T2 (hu)	2011-06-10	2018-08-28	Univ Oregon Health & Science	CMV glikoproteinek és rekombináns vektorok
CA2789539A1 (en)	2011-09-12	2013-03-12	International Aids Vaccine Initiative	Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
US9402894B2 (en)	2011-10-27	2016-08-02	International Aids Vaccine Initiative	Viral particles derived from an enveloped virus
ES2631608T3 (es)	2012-06-27	2017-09-01	International Aids Vaccine Initiative	Variante de la glicoproteína Env del VIH-1
DE102013205346A1 (de) *	2013-03-26	2014-10-02	Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.	Lanthanoidkomplexbasierte spektroskopische Hämoglobinbestimmung in einem flüssigen biologischen Medium
KR101423589B1 (ko)	2013-03-27	2014-07-28	주식회사 메디센서	란탄족 착물을 포함하는 무독성 형광 입자
EP2848937A1 (de)	2013-09-05	2015-03-18	International Aids Vaccine Initiative	Verfahren zur Identifizierung neuartiger HIV-1-Immunogene
US10058604B2 (en)	2013-10-07	2018-08-28	International Aids Vaccine Initiative	Soluble HIV-1 envelope glycoprotein trimers
FI125976B (en) *	2014-10-27	2016-05-13	Aqsens Oy	Method for determination of phosphonates
EP3069730A3 (de)	2015-03-20	2017-03-15	International Aids Vaccine Initiative	Lösliche hiv-1-hüllglykoproteintrimere
US9931394B2 (en)	2015-03-23	2018-04-03	International Aids Vaccine Initiative	Soluble HIV-1 envelope glycoprotein trimers
CA3010895A1 (en)	2016-01-21	2017-07-27	SeLux Diagnostics, Inc.	Methods for rapid antimicrobial susceptibility testing
US9834808B2 (en)	2016-01-21	2017-12-05	SeLux Diagnostics, Inc.	Methods for rapid antibiotic susceptibility testing
US11614445B2 (en)	2016-06-09	2023-03-28	Radiometer Turku Oy	Background blockers for binding assays
WO2018119439A1 (en)	2016-12-23	2018-06-28	SeLux Diagnostics, Inc.	Methods for improved rapid antimicrobial susceptibility testing
WO2018144633A1 (en) *	2017-01-31	2018-08-09	Theranos Ip Company, Llc	Methods and devices for improved signal detection from biological samples
CN113607953B (zh) *	2021-08-02	2025-01-28	中国科学院江西稀土研究院	一种稀土配合物荧光微球及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5004565A (en) *	1986-07-17	1991-04-02	The Board Of Governors Of Wayne State University	Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes
CA1340527C (en) *	1988-05-31	1999-05-04	Lidia Vallarino	Macrocyclic complexes of yttrium, the lanthanides and the actinides having peripheral coupling functionalities
FI88654C (fi) *	1991-03-15	1993-06-10	Datacity Center Oy	Fluorescenshoejningsmetod
US5696240A (en)	1991-03-15	1997-12-09	Vallarino; Lidia M.	Macrocyclic complexes of yttrium, the lanthanides and the actinides having peripheral coupling functionalities
WO1993011433A1 (en) *	1991-12-05	1993-06-10	Wallac Oy	Luminescent lanthanide chelates
US6340744B1 (en) *	1999-01-19	2002-01-22	Robert C. Leif	Reagent system and method for increasing the luminescence of lanthanide(III) macrocyclic complexes

2000
- 2000-01-18 US US09/484,670 patent/US6340744B1/en not_active Expired - Fee Related
- 2000-01-18 DE DE60011877T patent/DE60011877D1/de not_active Expired - Lifetime
- 2000-01-18 WO PCT/US2000/001211 patent/WO2000042048A1/en not_active Ceased
- 2000-01-18 EP EP00905653A patent/EP1150985B1/de not_active Expired - Lifetime
- 2000-01-18 AT AT00905653T patent/ATE270298T1/de not_active IP Right Cessation
- 2000-01-18 CA CA002360054A patent/CA2360054A1/en not_active Abandoned
2001
- 2001-12-06 US US10/010,597 patent/US6750005B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP1150985A1 (de)	2001-11-07
EP1150985A4 (de)	2002-03-20
US20020132992A1 (en)	2002-09-19
EP1150985B1 (de)	2004-06-30
CA2360054A1 (en)	2000-07-20
US6750005B2 (en)	2004-06-15
DE60011877D1 (de)	2004-08-05
WO2000042048A1 (en)	2000-07-20
US6340744B1 (en)	2002-01-22

Legal Events

Date	Code	Title	Description
2004-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE270298T1 (de)	2004-07-15	Reaktionssystem und verfahren zur verstärkung der lumineszenz von makrocyclischen lanthanid(iii)- komplexen
ATE210170T1 (de)	2001-12-15	Tintenstrahltinte
ATE272049T1 (de)	2004-08-15	Salicylamid-lanthanid komplexe zur verwendung als lumineszenzmarker
EP1138743A4 (de)	2005-01-19	Fluoreszierende oder phosphoreszierende zusammensetzung
KR960019042A (ko)	1996-06-17	축광성 형광체
EP1323808A3 (de)	2004-03-17	Organische elektrolumineszente Vorrichtung
BR0316886A (pt)	2005-10-25	Composição, processo para a preparação de uma composição, produto para contraste, usos de uma composição e uso de partìculas magnéticas
BG104951A (en)	2001-05-31	Method for marking liquids with at least two marker substances and method for detecting them
DE69200445D1 (de)	1994-10-27	Verfahren zur lumineszenzmessung in einer lumineszenzbestimmung.
BR9904790A (pt)	2000-03-08	Documento valioso.
ES2132962T3 (es)	1999-08-16	Metodo y sistema para determinar la autenticidad de un portador de datos, asi como soporte de datos a utilizar en el sistema.
ATE239912T1 (de)	2003-05-15	Verfahren und vorrichtung zur referenzierung von fluoreszenzintensitätssignalen
MXPA02011299A (es)	2003-06-06	Metodo aparato y sistema de seguridad, para la autentificaci°n de un marcado.
DE3587793D1 (de)	1994-05-11	Lumineszierende metallchelatmarker und mittel zu deren nachweis.
CA2069145A1 (en)	1992-11-23	Assay method utilizing induced luminescence
ATE277143T1 (de)	2004-10-15	Elektrolumineszenzmaterialen
CA2434091A1 (en)	2003-02-13	Radiation detector comprising a hybrid perovskite scintillator
GB9927292D0 (en)	2000-01-12	Security system
EP0354847A3 (de)	1991-08-28	Mehrfache Fluoreszenzmarkierung mit Europiumchelatoren
TR200200593T2 (tr)	2002-07-22	Lakton içeren, yüksek molekül ağırlıklı bileşiklerin seperasyonuna yönelik metod.
ATE156592T1 (de)	1997-08-15	Verfahren zum nachweis von substanzen
WO2000006989A3 (en)	2000-03-23	Apparatus and methods for identifying quenching effects in luminescence assays
EP0525181A4 (en)	1993-03-10	Novel lanthanide chelate-conjugated oligonucleotides
ATE459635T1 (de)	2010-03-15	Fluoreszierende cobalamine und deren verwendung
KR960004218A (ko)	1996-02-23	도핑 처리된 이트륨, 루테튬 또는 가돌리늄의 탄탈산염의 저전압 발광 용도