ATE336509T1 - Verwendung von taci als antitumormittel - Google Patents
Verwendung von taci als antitumormittelInfo
- Publication number
- ATE336509T1 ATE336509T1 AT01927474T AT01927474T ATE336509T1 AT E336509 T1 ATE336509 T1 AT E336509T1 AT 01927474 T AT01927474 T AT 01927474T AT 01927474 T AT01927474 T AT 01927474T AT E336509 T1 ATE336509 T1 AT E336509T1
- Authority
- AT
- Austria
- Prior art keywords
- taci
- mammal
- antitumor agent
- reagent
- administering
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 3
- 239000003153 chemical reaction reagent Substances 0.000 abstract 3
- 101000795167 Homo sapiens Tumor necrosis factor receptor superfamily member 13B Proteins 0.000 abstract 2
- 102100029675 Tumor necrosis factor receptor superfamily member 13B Human genes 0.000 abstract 2
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 230000004083 survival effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19994600P | 2000-04-27 | 2000-04-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE336509T1 true ATE336509T1 (de) | 2006-09-15 |
Family
ID=22739664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01927474T ATE336509T1 (de) | 2000-04-27 | 2001-04-27 | Verwendung von taci als antitumormittel |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1297013B1 (de) |
| JP (1) | JP2004513876A (de) |
| AT (1) | ATE336509T1 (de) |
| AU (2) | AU2001253920B2 (de) |
| CA (1) | CA2404945C (de) |
| CY (1) | CY1105788T1 (de) |
| DE (1) | DE60122337T2 (de) |
| DK (1) | DK1297013T3 (de) |
| ES (1) | ES2271004T3 (de) |
| NZ (1) | NZ521629A (de) |
| PT (1) | PT1297013E (de) |
| SI (1) | SI1297013T1 (de) |
| WO (1) | WO2001081417A2 (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7217788B2 (en) | 1996-03-14 | 2007-05-15 | Human Genome Sciences, Inc. | Human tumor necrosis factor delta polypeptides |
| US6541224B2 (en) | 1996-03-14 | 2003-04-01 | Human Genome Sciences, Inc. | Tumor necrosis factor delta polypeptides |
| US8212004B2 (en) | 1999-03-02 | 2012-07-03 | Human Genome Sciences, Inc. | Neutrokine-alpha fusion proteins |
| US6812327B1 (en) | 1996-10-25 | 2004-11-02 | Human Genome Sciences, Inc. | Neutrokine-alpha polypeptides |
| US7833529B1 (en) | 1999-01-07 | 2010-11-16 | Zymogenetics, Inc. | Methods for inhibiting B lymphocyte proliferation with soluble ztnf4 receptor |
| US7879328B2 (en) | 2000-06-16 | 2011-02-01 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to B lymphocyte stimulator |
| PT2281843T (pt) | 2000-06-16 | 2017-01-02 | Human Genome Sciences Inc | Anticorpos que se ligam imunoespecificamente a blys |
| AU2001288301A1 (en) | 2000-08-18 | 2002-03-04 | Human Genome Sciences, Inc. | Binding polypeptides and methods based thereon |
| AU8506601A (en) | 2000-08-18 | 2002-03-04 | Dyax Corp | Binding polypeptides for b lymphocyte stimulator protein (blys) |
| AU2002215753A1 (en) * | 2000-12-07 | 2002-06-18 | The University Of British Columbia | Caml-binding peptides |
| EP1401870A4 (de) | 2001-05-24 | 2006-04-19 | Human Genome Sciences | Antikörper gegen tumor necrosis factor delta (april) |
| BRPI0209933B8 (pt) | 2001-05-24 | 2021-05-25 | Zymogenetics Inc | proteína de fusão, e, molécula de ácido nucleico |
| JP2007526220A (ja) | 2003-06-05 | 2007-09-13 | ジェネンテック・インコーポレーテッド | B細胞疾患の併用療法 |
| US20070249530A1 (en) | 2004-01-29 | 2007-10-25 | Genentech, Inc. | Bcma Polypeptides and Uses Thereof |
| EP1922080A2 (de) * | 2005-08-09 | 2008-05-21 | ZymoGenetics, Inc. | Verfahren zur behandlung von b-zell-malignomen mittels taci-ig-fusionsmolekül |
| WO2007019573A2 (en) * | 2005-08-09 | 2007-02-15 | Zymogenetics, Inc. | Methods for the treatment and prevention of abnormal cell proliferation using taci-fusion molecules |
| US9168286B2 (en) | 2005-10-13 | 2015-10-27 | Human Genome Sciences, Inc. | Methods and compositions for use in treatment of patients with autoantibody positive disease |
| WO2007142667A2 (en) | 2005-10-13 | 2007-12-13 | Human Genome Sciences, Inc. | Treatment of patients with autoantibody positive disease |
| ES2618543T3 (es) | 2005-11-23 | 2017-06-21 | Genentech, Inc. | Métodos y composiciones relacionados con ensayos de linfocitos B |
| WO2007123765A2 (en) | 2006-03-31 | 2007-11-01 | Human Genome Sciences Inc. | Neutrokine-alpha and neutrokine-alpha splice variant |
| BRPI0711823A2 (pt) * | 2006-05-15 | 2012-01-17 | Ares Trading Sa | métodos para tratamento de doenças auto-imunes com uma molécula de fusão taci-ig |
| CN101323643B (zh) * | 2007-06-15 | 2010-12-01 | 烟台荣昌生物工程有限公司 | 优化的TACI-Fc融合蛋白 |
| HUE030134T2 (en) | 2007-10-16 | 2017-04-28 | Zymogenetics Inc | Combination of transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) and anti-CD20 agents for the treatment of autoimmune diseases |
| WO2011109280A1 (en) | 2010-03-05 | 2011-09-09 | Lerner Research Institute | Methods and compositions to treat immune-mediated disorders |
| GB201317929D0 (en) * | 2013-10-10 | 2013-11-27 | Ucl Business Plc | Chimeric antigen receptor |
| JP7385556B2 (ja) * | 2017-09-01 | 2023-11-22 | デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド | Bcma抗原に特異的な免疫原性ペプチドおよびその使用 |
| JP7749319B2 (ja) | 2017-10-10 | 2025-10-06 | アルパイン イミューン サイエンシズ インコーポレイテッド | Ctla-4変異型免疫調節タンパク質およびそれらの使用 |
| EP4146684A2 (de) | 2020-05-08 | 2023-03-15 | Alpine Immune Sciences, Inc. | April- und baff-hemmende immunmodulatorische proteine mit und ohne t-zell-hemmendes protein und verfahren zur verwendung davon |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5969102A (en) * | 1997-03-03 | 1999-10-19 | St. Jude Children's Research Hospital | Lymphocyte surface receptor that binds CAML, nucleic acids encoding the same and methods of use thereof |
| SI1642972T1 (sl) * | 1999-01-07 | 2010-05-31 | Zymogenetics Inc | Terapevtske uporabe BR X topnih receptorjev |
| WO2000058362A1 (en) * | 1999-03-26 | 2000-10-05 | Human Genome Sciences, Inc. | Neutrokine-alpha binding proteins and methods based thereon |
-
2001
- 2001-04-27 DK DK01927474T patent/DK1297013T3/da active
- 2001-04-27 ES ES01927474T patent/ES2271004T3/es not_active Expired - Lifetime
- 2001-04-27 AT AT01927474T patent/ATE336509T1/de active
- 2001-04-27 JP JP2001578504A patent/JP2004513876A/ja not_active Withdrawn
- 2001-04-27 SI SI200130650T patent/SI1297013T1/sl unknown
- 2001-04-27 PT PT01927474T patent/PT1297013E/pt unknown
- 2001-04-27 AU AU2001253920A patent/AU2001253920B2/en not_active Ceased
- 2001-04-27 AU AU5392001A patent/AU5392001A/xx active Pending
- 2001-04-27 NZ NZ521629A patent/NZ521629A/en not_active IP Right Cessation
- 2001-04-27 CA CA2404945A patent/CA2404945C/en not_active Expired - Lifetime
- 2001-04-27 EP EP01927474A patent/EP1297013B1/de not_active Expired - Lifetime
- 2001-04-27 DE DE60122337T patent/DE60122337T2/de not_active Expired - Lifetime
- 2001-04-27 WO PCT/US2001/040626 patent/WO2001081417A2/en not_active Ceased
-
2006
- 2006-11-15 CY CY20061101667T patent/CY1105788T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2271004T3 (es) | 2007-04-16 |
| AU2001253920B2 (en) | 2006-03-16 |
| JP2004513876A (ja) | 2004-05-13 |
| DE60122337D1 (de) | 2006-09-28 |
| CY1105788T1 (el) | 2011-02-02 |
| DE60122337T2 (de) | 2007-08-16 |
| AU5392001A (en) | 2001-11-07 |
| SI1297013T1 (sl) | 2007-06-30 |
| CA2404945A1 (en) | 2001-11-01 |
| DK1297013T3 (da) | 2006-12-27 |
| NZ521629A (en) | 2004-05-28 |
| PT1297013E (pt) | 2006-12-29 |
| WO2001081417A3 (en) | 2002-06-20 |
| WO2001081417A2 (en) | 2001-11-01 |
| EP1297013B1 (de) | 2006-08-16 |
| EP1297013A2 (de) | 2003-04-02 |
| CA2404945C (en) | 2010-02-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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