ATE272117T1 - Rekombinante zellen der monozyten-makrophagen zelllinie zur gen-therapie - Google Patents

Rekombinante zellen der monozyten-makrophagen zelllinie zur gen-therapie

Info

Publication number
ATE272117T1
ATE272117T1 AT94925523T AT94925523T ATE272117T1 AT E272117 T1 ATE272117 T1 AT E272117T1 AT 94925523 T AT94925523 T AT 94925523T AT 94925523 T AT94925523 T AT 94925523T AT E272117 T1 ATE272117 T1 AT E272117T1
Authority
AT
Austria
Prior art keywords
monocyte
cell line
gene therapy
recombinant cells
macrophage cell
Prior art date
Application number
AT94925523T
Other languages
English (en)
Inventor
Hedi Haddada
Manuel Lopez
Michel Perricaudet
Original Assignee
Aventis Pharma Sa
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa, Inst Nat Sante Rech Med filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of ATE272117T1 publication Critical patent/ATE272117T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT94925523T 1993-08-25 1994-08-22 Rekombinante zellen der monozyten-makrophagen zelllinie zur gen-therapie ATE272117T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9310222A FR2709309B1 (fr) 1993-08-25 1993-08-25 Compositions cellulaires, préparation et utilisations thérapeutiques.
PCT/FR1994/001019 WO1995006120A1 (fr) 1993-08-25 1994-08-22 Cellules recombinantes de la lignee monocyte-macrophage pour la therapie genique

Publications (1)

Publication Number Publication Date
ATE272117T1 true ATE272117T1 (de) 2004-08-15

Family

ID=9450378

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94925523T ATE272117T1 (de) 1993-08-25 1994-08-22 Rekombinante zellen der monozyten-makrophagen zelllinie zur gen-therapie

Country Status (14)

Country Link
US (1) US6210963B1 (de)
EP (1) EP0719332B1 (de)
JP (1) JP3731035B2 (de)
KR (1) KR100392984B1 (de)
AT (1) ATE272117T1 (de)
AU (1) AU698043B2 (de)
CA (1) CA2170159A1 (de)
DE (1) DE69433921T2 (de)
FI (1) FI960855A7 (de)
FR (1) FR2709309B1 (de)
IL (1) IL110754A (de)
NO (1) NO319990B1 (de)
WO (1) WO1995006120A1 (de)
ZA (1) ZA946264B (de)

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FR2746109B1 (fr) 1996-03-12 1998-04-17 Rhone Poulenc Rorer Sa Milieu pour la conservation de materiel biologique
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AU2001261737A1 (en) * 2000-05-18 2001-11-26 Genetix Pharmaceuticals, Inc. Methods and compositions for promoting angiogenesis using monocytes
US6579522B1 (en) 2000-06-27 2003-06-17 Genvec, Inc. Replication deficient adenoviral TNF vector
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EP2241330A1 (de) 2003-02-14 2010-10-20 The Curators Of The University Of Missouri Empfängnisverhütende Verfahren und Zusammensetzungen betreffend proteasomale Störung
US20080038234A1 (en) * 2004-03-23 2008-02-14 Shuji Hayashi Bone Marrow-Related Cells Associated With Tissue Maintenance And/Or Repair
US7838503B2 (en) * 2005-06-15 2010-11-23 Children's Medical Center Corporation Methods for extending the replicative lifespan of cells
CN101548008B (zh) 2006-10-04 2013-04-17 詹森药业有限公司 失活的人工抗原提呈细胞的制备及其在细胞疗法中的用途
PL2106440T3 (pl) * 2007-01-12 2016-02-29 Univ Illinois Komórki niepochodzące od małp do hodowli wirusa zespołu rozrodczo-oddechowego świń (PRRS)
JP5546107B2 (ja) * 2008-04-17 2014-07-09 国立大学法人宇都宮大学 RNAウイルスBmMLV陰性カイコ培養細胞株
EP2248903A1 (de) * 2009-04-29 2010-11-10 Universitat Autònoma De Barcelona Verfahren und Reagenzien zum effizienten und gezielten Gentransfer in Monozyten und Makrophagen
WO2011119920A2 (en) 2010-03-25 2011-09-29 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
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AU2012216792A1 (en) 2011-09-12 2013-03-28 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing HIV-1 proteins by broadly neutralizing antibodies
EP2586461A1 (de) 2011-10-27 2013-05-01 Christopher L. Parks Von einem eingehüllten Virus abgeleitete Virenpartikel
EP2679596B1 (de) 2012-06-27 2017-04-12 International Aids Vaccine Initiative HIV-1 Env-proteinvariante
EP3461491B1 (de) 2013-04-18 2024-11-13 TILT Biotherapeutics Oy Verbesserte adoptive zelltherapie
US12421502B2 (en) 2013-04-18 2025-09-23 Tilt Biotherapeutics Oy Enhanced adoptive cell therapy
US20150065381A1 (en) 2013-09-05 2015-03-05 International Aids Vaccine Initiative Methods of identifying novel hiv-1 immunogens
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US20170151281A1 (en) 2015-02-19 2017-06-01 Batu Biologics, Inc. Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer
US10174292B2 (en) 2015-03-20 2019-01-08 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
EP3072901A1 (de) 2015-03-23 2016-09-28 International Aids Vaccine Initiative Lösliche hiv-1-hüllglykoproteintrimere
IL260987B2 (en) 2016-02-04 2024-09-01 Zhenglun Zhu Treatment and diagnosis of inflammatory disorders
WO2018183447A1 (en) * 2017-03-28 2018-10-04 Zhenglun Zhu Methods of treating neoplastic diseases
EP3876977A1 (de) 2018-11-06 2021-09-15 The Regents Of The University Of California Chimäre antigen-rezeptoren für phagocytose
US11026973B2 (en) 2019-04-30 2021-06-08 Myeloid Therapeutics, Inc. Engineered phagocytic receptor compositions and methods of use thereof
WO2021046243A2 (en) 2019-09-03 2021-03-11 Myeloid Therapeutics, Inc. Methods and compositions for genomic integration
US10980836B1 (en) 2019-12-11 2021-04-20 Myeloid Therapeutics, Inc. Therapeutic cell compositions and methods of manufacturing and use thereof
EP4240367A4 (de) 2020-11-04 2024-10-16 Myeloid Therapeutics, Inc. Manipulierte chimäre fusionsproteinzusammensetzungen und verfahren zur verwendung davon
KR20240013094A (ko) 2021-03-17 2024-01-30 마이얼로이드 테라퓨틱스, 인크. 조작된 키메라 융합 단백질 조성물 및 그의 사용 방법
JP2024512808A (ja) 2021-04-05 2024-03-19 ヤンセン バイオテツク,インコーポレーテツド Calr及びjak2t細胞受容体
WO2022241029A1 (en) 2021-05-11 2022-11-17 Myeloid Therapeutics, Inc. Methods and compositions for genomic integration
CN114657143B (zh) * 2022-03-11 2022-10-25 西安电子科技大学 一种肿瘤微环境调控型car-单核/巨噬细胞及其制备方法和应用

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US5399493A (en) * 1989-06-15 1995-03-21 The Regents Of The University Of Michigan Methods and compositions for the optimization of human hematopoietic progenitor cell cultures
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US5436151A (en) * 1992-04-03 1995-07-25 Regents Of The University Of Minnesota Method for culturing human hematopoietic stem cells in vitro
DE4219626A1 (de) * 1992-06-16 1993-12-23 Wehling Peter Priv Doz Dr Med Methode zur Einschleusung therapeutisch relevanter Gene in Körperzellen
AU692152B2 (en) * 1993-03-17 1998-06-04 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Immunogenic chimeras comprising nucleic acid sequences encoding endoplasmic reticulum signal sequence peptides and at least one other peptide, and their uses in vaccines and disease treatments
US5543328A (en) * 1993-08-13 1996-08-06 Genetic Therapy, Inc. Adenoviruses having modified fiber proteins
AU5297496A (en) * 1995-02-17 1996-09-04 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Methods of preparation and use of recombinant adenoviral vectors

Also Published As

Publication number Publication date
NO960743L (no) 1996-03-25
AU7539894A (en) 1995-03-21
IL110754A0 (en) 1994-11-11
EP0719332A1 (de) 1996-07-03
AU698043B2 (en) 1998-10-22
WO1995006120A1 (fr) 1995-03-02
FR2709309A1 (fr) 1995-03-03
US6210963B1 (en) 2001-04-03
CA2170159A1 (fr) 1995-03-02
DE69433921D1 (de) 2004-09-02
FI960855A0 (fi) 1996-02-23
EP0719332B1 (de) 2004-07-28
JPH09501837A (ja) 1997-02-25
FI960855L (fi) 1996-04-23
NO960743D0 (no) 1996-02-23
ZA946264B (en) 1995-03-20
DE69433921T2 (de) 2006-10-05
IL110754A (en) 2001-04-30
FI960855A7 (fi) 1996-04-23
JP3731035B2 (ja) 2006-01-05
FR2709309B1 (fr) 1995-11-10
NO319990B1 (no) 2005-10-10
KR100392984B1 (ko) 2004-10-20

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