ATE272399T1 - Zusammensetzungen aus aminosäuren zur behandlung von herzinsuffizienz - Google Patents
Zusammensetzungen aus aminosäuren zur behandlung von herzinsuffizienzInfo
- Publication number
- ATE272399T1 ATE272399T1 AT01940935T AT01940935T ATE272399T1 AT E272399 T1 ATE272399 T1 AT E272399T1 AT 01940935 T AT01940935 T AT 01940935T AT 01940935 T AT01940935 T AT 01940935T AT E272399 T1 ATE272399 T1 AT E272399T1
- Authority
- AT
- Austria
- Prior art keywords
- amino acids
- amino acid
- active ingredients
- treatment
- heart failure
- Prior art date
Links
- 150000001413 amino acids Chemical class 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 206010019280 Heart failures Diseases 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 3
- 229940024606 amino acid Drugs 0.000 abstract 3
- 206010011732 Cyst Diseases 0.000 abstract 2
- 208000031513 cyst Diseases 0.000 abstract 2
- 235000020776 essential amino acid Nutrition 0.000 abstract 2
- 239000003797 essential amino acid Substances 0.000 abstract 2
- OCUSNPIJIZCRSZ-ZTZWCFDHSA-N (2s)-2-amino-3-methylbutanoic acid;(2s)-2-amino-4-methylpentanoic acid;(2s,3s)-2-amino-3-methylpentanoic acid Chemical compound CC(C)[C@H](N)C(O)=O.CC[C@H](C)[C@H](N)C(O)=O.CC(C)C[C@H](N)C(O)=O OCUSNPIJIZCRSZ-ZTZWCFDHSA-N 0.000 abstract 1
- LEVWYRKDKASIDU-QWWZWVQMSA-N D-cystine Chemical compound OC(=O)[C@H](N)CSSC[C@@H](N)C(O)=O LEVWYRKDKASIDU-QWWZWVQMSA-N 0.000 abstract 1
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 abstract 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 abstract 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N THREONINE Chemical compound CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 abstract 1
- 150000005693 branched-chain amino acids Chemical class 0.000 abstract 1
- 229960003067 cystine Drugs 0.000 abstract 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 abstract 1
- 229930182817 methionine Natural products 0.000 abstract 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 abstract 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2000TO000674A IT1320782B1 (it) | 2000-07-04 | 2000-07-04 | Composizioni a base di aminoacidi, atte al trattamentodell'insufficienza cardiaca. |
| PCT/IB2001/001181 WO2002002103A2 (en) | 2000-07-04 | 2001-06-28 | Compositions based on aminoacids, suitable for the treatment of heart failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE272399T1 true ATE272399T1 (de) | 2004-08-15 |
Family
ID=11457893
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01940935T ATE272399T1 (de) | 2000-07-04 | 2001-06-28 | Zusammensetzungen aus aminosäuren zur behandlung von herzinsuffizienz |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7902250B2 (de) |
| EP (1) | EP1296675B1 (de) |
| JP (1) | JP2004501968A (de) |
| KR (1) | KR100817348B1 (de) |
| AT (1) | ATE272399T1 (de) |
| AU (1) | AU2001274421A1 (de) |
| CA (1) | CA2411937C (de) |
| DE (1) | DE60104695T2 (de) |
| DK (1) | DK1296675T3 (de) |
| ES (1) | ES2225555T3 (de) |
| IT (1) | IT1320782B1 (de) |
| PT (1) | PT1296675E (de) |
| TR (1) | TR200402654T4 (de) |
| WO (1) | WO2002002103A2 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITTO20010580A1 (it) * | 2001-06-15 | 2002-12-15 | Professional Dietetics Srl | Composizioni a base di aminoacidi per il miglioramento della funzioneventricolare miocardica in pazienti affetti da diabete. |
| FI109970B (fi) * | 2002-02-20 | 2002-11-15 | Remedal Oy | Valmiste ja menetelmä painon pudottamiseksi |
| JP2008056566A (ja) * | 2004-12-28 | 2008-03-13 | Toudai Tlo Ltd | 低酸素応答促進剤 |
| ITTO20080443A1 (it) | 2008-06-06 | 2009-12-07 | Professional Dietetics Srl | Composizioni comprendenti amminoacidi, con attivita' pro-angiogenica |
| KR101458670B1 (ko) * | 2012-03-30 | 2014-11-06 | 주식회사 서울제약 | 분지쇄아미노산을 함유하는 약제학적 조성물 및 그 제조방법 |
| JP5477413B2 (ja) * | 2012-04-24 | 2014-04-23 | 味の素株式会社 | 分岐鎖アミノ酸の心不全適応 |
| US9730916B2 (en) * | 2014-02-27 | 2017-08-15 | Chang Gung Memorial Hospital, Keelung | Nutritional composition and method for improving heart failure |
| JOP20190146A1 (ar) | 2016-12-19 | 2019-06-18 | Axcella Health Inc | تركيبات حمض أميني وطرق لمعالجة أمراض الكبد |
| EP3668499A1 (de) | 2017-08-14 | 2020-06-24 | Axcella Health Inc. | Aminosäurezusammensetzungen zur behandlung von lebererkrankungen |
| WO2019246225A1 (en) | 2018-06-20 | 2019-12-26 | Axcella Health Inc. | Compositions and methods for the treatment of fat infiltration in muscle |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4059694A (en) * | 1976-05-05 | 1977-11-22 | The University Of Hawaii | Cardiotonic agent |
| JPS6087221A (ja) * | 1983-10-19 | 1985-05-16 | Eisai Co Ltd | 心疾患治療・予防剤 |
| US5032608A (en) * | 1986-09-10 | 1991-07-16 | Dudrick Stanley J | Method and substrate composition for treating atherosclerosis |
| US5036052A (en) * | 1988-06-22 | 1991-07-30 | Morishita Pharmaceutical Co., Ltd. | Amino acid nutrient compositions |
| AU655780B2 (en) * | 1990-10-30 | 1995-01-12 | Clintec Nutrition Company | A method and composition for the protection of a metabolic recovery of ischemic cardiac tissue |
| US5198465A (en) * | 1991-06-19 | 1993-03-30 | Dioguardi Francesco S | Compositions based on amino acids for preventing and treating precursor deficiencies in the synthesis of collagen |
| ATE174794T1 (de) * | 1991-09-27 | 1999-01-15 | Univ Texas | Parenteral anzuwendende aminosäuren enthaltende zubereitungen zur bekämpfung von hypotension und verwandten pathologien |
| US5276018A (en) * | 1992-07-17 | 1994-01-04 | Brigham And Women's Hospital | Composition comprising amino acids and methods for decreasing muscle breakdown |
| IT1289754B1 (it) | 1996-12-16 | 1998-10-16 | Professional Dietetics Srl | Composizioni a base di aminoacidi |
| US6329342B1 (en) * | 1997-08-19 | 2001-12-11 | Eli Lilly And Company | Treatment of congestive heart failure with growth hormone secretagogues |
| IT1304191B1 (it) * | 1998-12-18 | 2001-03-08 | Solartium Establishment | Composizione farmaceutica a base di prolina, glicina e lisina utilenella terapia odontoiatrica sia sotto forma iniettabile che in |
-
2000
- 2000-07-04 IT IT2000TO000674A patent/IT1320782B1/it active
-
2001
- 2001-06-28 TR TR2004/02654T patent/TR200402654T4/xx unknown
- 2001-06-28 WO PCT/IB2001/001181 patent/WO2002002103A2/en not_active Ceased
- 2001-06-28 AT AT01940935T patent/ATE272399T1/de active
- 2001-06-28 US US10/332,236 patent/US7902250B2/en not_active Expired - Fee Related
- 2001-06-28 DE DE60104695T patent/DE60104695T2/de not_active Expired - Lifetime
- 2001-06-28 JP JP2002506725A patent/JP2004501968A/ja active Pending
- 2001-06-28 EP EP01940935A patent/EP1296675B1/de not_active Expired - Lifetime
- 2001-06-28 DK DK01940935T patent/DK1296675T3/da active
- 2001-06-28 CA CA2411937A patent/CA2411937C/en not_active Expired - Fee Related
- 2001-06-28 PT PT01940935T patent/PT1296675E/pt unknown
- 2001-06-28 AU AU2001274421A patent/AU2001274421A1/en not_active Abandoned
- 2001-06-28 ES ES01940935T patent/ES2225555T3/es not_active Expired - Lifetime
- 2001-06-28 KR KR1020027017508A patent/KR100817348B1/ko not_active Expired - Fee Related
-
2011
- 2011-01-26 US US13/014,294 patent/US8536216B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002002103A3 (en) | 2002-05-02 |
| KR100817348B1 (ko) | 2008-03-26 |
| WO2002002103A2 (en) | 2002-01-10 |
| JP2004501968A (ja) | 2004-01-22 |
| US20040102504A1 (en) | 2004-05-27 |
| ES2225555T3 (es) | 2005-03-16 |
| ITTO20000674A0 (it) | 2000-07-04 |
| CA2411937C (en) | 2010-06-01 |
| US20110124697A1 (en) | 2011-05-26 |
| KR20030013452A (ko) | 2003-02-14 |
| AU2001274421A1 (en) | 2002-01-14 |
| US7902250B2 (en) | 2011-03-08 |
| DK1296675T3 (da) | 2004-12-06 |
| EP1296675A2 (de) | 2003-04-02 |
| IT1320782B1 (it) | 2003-12-10 |
| CA2411937A1 (en) | 2002-01-10 |
| US8536216B2 (en) | 2013-09-17 |
| DE60104695T2 (de) | 2005-08-18 |
| DE60104695D1 (de) | 2004-09-09 |
| EP1296675B1 (de) | 2004-08-04 |
| PT1296675E (pt) | 2004-11-30 |
| ITTO20000674A1 (it) | 2002-01-04 |
| TR200402654T4 (tr) | 2004-11-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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