ATE273296T1 - 3-pyridyloxymethyl heterocyclische ether verbindungen für die kontrolle chemischer synaptischer übertragung - Google Patents
3-pyridyloxymethyl heterocyclische ether verbindungen für die kontrolle chemischer synaptischer übertragungInfo
- Publication number
- ATE273296T1 ATE273296T1 AT97927830T AT97927830T ATE273296T1 AT E273296 T1 ATE273296 T1 AT E273296T1 AT 97927830 T AT97927830 T AT 97927830T AT 97927830 T AT97927830 T AT 97927830T AT E273296 T1 ATE273296 T1 AT E273296T1
- Authority
- AT
- Austria
- Prior art keywords
- ether compounds
- synaptic transmission
- heterocyclic ether
- controlling chemical
- chemical synaptic
- Prior art date
Links
- -1 3-PYRIDYLOXYMETHYL Chemical class 0.000 title abstract 2
- 230000005062 synaptic transmission Effects 0.000 title abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical class CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
- 108091006146 Channels Proteins 0.000 abstract 1
- 230000001713 cholinergic effect Effects 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/660,044 US5629325A (en) | 1996-06-06 | 1996-06-06 | 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling chemical synaptic transmission |
| US08/844,540 US6127386A (en) | 1996-06-06 | 1997-04-18 | 3-Pyridyloxymethyl heterocyclic ether compounds useful in controlling chemical synaptic transmission |
| PCT/US1997/009167 WO1997046554A1 (en) | 1996-06-06 | 1997-06-04 | 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling chemical synaptic transmission |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE273296T1 true ATE273296T1 (de) | 2004-08-15 |
Family
ID=24647894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97927830T ATE273296T1 (de) | 1996-06-06 | 1997-06-04 | 3-pyridyloxymethyl heterocyclische ether verbindungen für die kontrolle chemischer synaptischer übertragung |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US5629325A (de) |
| EP (1) | EP0934308B1 (de) |
| JP (2) | JP4486712B2 (de) |
| AT (1) | ATE273296T1 (de) |
| CA (1) | CA2256022C (de) |
| DE (1) | DE69730229T2 (de) |
| DK (1) | DK0934308T3 (de) |
| ES (1) | ES2229364T3 (de) |
| PT (1) | PT934308E (de) |
| WO (1) | WO1997046554A1 (de) |
Families Citing this family (78)
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| US5629325A (en) * | 1996-06-06 | 1997-05-13 | Abbott Laboratories | 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling chemical synaptic transmission |
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| DE69717148T2 (de) * | 1996-12-10 | 2003-10-02 | Abbott Laboratories, Abbott Park | 3-pyridylenantiomere und ihre verwendung als analgetika |
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| MXPA00009619A (es) | 1998-04-02 | 2006-03-09 | Targacept Inc | Composiciones farmaceuticas y metodos de uso. |
| US6723838B1 (en) | 1998-04-22 | 2004-04-20 | Johns Hopkins University | Signal transducing synaptic molecules and uses thereof |
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| AU2016211330A1 (en) | 2015-01-28 | 2017-08-03 | Chrono Therapeutics Inc. | Drug delivery methods and systems |
| PT3317270T (pt) | 2015-07-02 | 2020-08-24 | Centrexion Therapeutics Corp | (4-((3r,4r)-3-metoxitetrahidro-pirano-4-ilamino)piperidina-1-il)(5-metil-6-(((2r,6s)-6-(p-tolil)tetrahidro-2h-pirano-2-il)metilamino)pirimidina-4-il)citrato de metanona |
| CA3049529A1 (en) | 2017-01-06 | 2018-07-12 | Chrono Therapeutics Inc. | Transdermal drug delivery devices and methods |
| US11596779B2 (en) | 2018-05-29 | 2023-03-07 | Morningside Venture Investments Limited | Drug delivery methods and systems |
| US12397141B2 (en) | 2018-11-16 | 2025-08-26 | Morningside Venture Investments Limited | Thermally regulated transdermal drug delivery system |
| AR131541A1 (es) | 2023-01-07 | 2025-04-09 | Syngenta Crop Protection Ag | Compuestos de carboxamida novedosos |
| WO2025109114A1 (en) | 2023-11-24 | 2025-05-30 | Syngenta Crop Protection Ag | Novel carboxamide compounds |
| WO2025149637A1 (en) | 2024-01-12 | 2025-07-17 | Syngenta Crop Protection Ag | Novel carboxamide compounds |
| PY2501648A (es) | 2024-01-12 | 2025-10-31 | Syngenta Crop Protection Ag | Nuevos compuestos de carboxamida |
| WO2026008750A1 (en) | 2024-07-05 | 2026-01-08 | Syngenta Crop Protection Ag | Novel carboxamide compounds |
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| FI95572C (fi) * | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
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| US5629325A (en) * | 1996-06-06 | 1997-05-13 | Abbott Laboratories | 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling chemical synaptic transmission |
-
1996
- 1996-06-06 US US08/660,044 patent/US5629325A/en not_active Expired - Lifetime
-
1997
- 1997-04-18 US US08/844,540 patent/US6127386A/en not_active Expired - Lifetime
- 1997-06-04 JP JP50068698A patent/JP4486712B2/ja not_active Expired - Fee Related
- 1997-06-04 DK DK97927830T patent/DK0934308T3/da active
- 1997-06-04 DE DE69730229T patent/DE69730229T2/de not_active Expired - Lifetime
- 1997-06-04 ES ES97927830T patent/ES2229364T3/es not_active Expired - Lifetime
- 1997-06-04 AT AT97927830T patent/ATE273296T1/de not_active IP Right Cessation
- 1997-06-04 WO PCT/US1997/009167 patent/WO1997046554A1/en not_active Ceased
- 1997-06-04 CA CA002256022A patent/CA2256022C/en not_active Expired - Fee Related
- 1997-06-04 PT PT97927830T patent/PT934308E/pt unknown
- 1997-06-04 EP EP97927830A patent/EP0934308B1/de not_active Expired - Lifetime
-
2009
- 2009-06-23 JP JP2009148236A patent/JP2009256360A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE69730229T2 (de) | 2005-07-28 |
| JP2002515038A (ja) | 2002-05-21 |
| ES2229364T3 (es) | 2005-04-16 |
| WO1997046554A1 (en) | 1997-12-11 |
| EP0934308B1 (de) | 2004-08-11 |
| JP4486712B2 (ja) | 2010-06-23 |
| CA2256022C (en) | 2008-07-29 |
| CA2256022A1 (en) | 1997-12-11 |
| DK0934308T3 (da) | 2004-12-06 |
| EP0934308A1 (de) | 1999-08-11 |
| PT934308E (pt) | 2004-11-30 |
| JP2009256360A (ja) | 2009-11-05 |
| US6127386A (en) | 2000-10-03 |
| US5629325A (en) | 1997-05-13 |
| DE69730229D1 (de) | 2004-09-16 |
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