ATE274356T1 - Verwendung von angiostatische steroide in photodynamischer therapie - Google Patents
Verwendung von angiostatische steroide in photodynamischer therapieInfo
- Publication number
- ATE274356T1 ATE274356T1 AT98931367T AT98931367T ATE274356T1 AT E274356 T1 ATE274356 T1 AT E274356T1 AT 98931367 T AT98931367 T AT 98931367T AT 98931367 T AT98931367 T AT 98931367T AT E274356 T1 ATE274356 T1 AT E274356T1
- Authority
- AT
- Austria
- Prior art keywords
- photodynamic therapy
- angiostatic steroids
- angiostatic
- steroids
- steriod
- Prior art date
Links
- 230000000964 angiostatic effect Effects 0.000 title abstract 2
- 238000002428 photodynamic therapy Methods 0.000 title abstract 2
- 150000003431 steroids Chemical class 0.000 title 1
- 206010029113 Neovascularisation Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J11/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0027—Azides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/895,184 US5770592A (en) | 1991-11-22 | 1997-07-16 | Prevention and treatment of ocular neovascularization using angiostatic steroids |
| PCT/US1998/012711 WO1999003503A1 (en) | 1997-07-16 | 1998-06-18 | The use of angiostatic steroids in photodynamic therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE274356T1 true ATE274356T1 (de) | 2004-09-15 |
Family
ID=25404127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98931367T ATE274356T1 (de) | 1997-07-16 | 1998-06-18 | Verwendung von angiostatische steroide in photodynamischer therapie |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US5770592A (de) |
| EP (1) | EP1003553B1 (de) |
| JP (1) | JP2001510170A (de) |
| AT (1) | ATE274356T1 (de) |
| AU (1) | AU734195B2 (de) |
| BR (1) | BR9811012A (de) |
| CA (1) | CA2296558A1 (de) |
| DE (1) | DE69825906T2 (de) |
| DK (1) | DK1003553T3 (de) |
| ES (1) | ES2224412T3 (de) |
| PT (1) | PT1003553E (de) |
| WO (1) | WO1999003503A1 (de) |
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| US6454789B1 (en) | 1999-01-15 | 2002-09-24 | Light Science Corporation | Patient portable device for photodynamic therapy |
| WO2000041726A2 (en) | 1999-01-15 | 2000-07-20 | Light Sciences Corporation | Noninvasive vascular therapy |
| EP1131100B1 (de) * | 1999-01-15 | 2003-03-12 | Light Sciences Corporation | Therapeutische zusammensetzungen fur knochenstoffwechselstörungen oder knochenmetastasen enthaltend einen photosensitizer und ein bisphosphonat |
| US6602274B1 (en) | 1999-01-15 | 2003-08-05 | Light Sciences Corporation | Targeted transcutaneous cancer therapy |
| AU775149B2 (en) | 1999-10-21 | 2004-07-22 | Alcon Inc. | Sub-tenon drug delivery |
| US7943162B2 (en) * | 1999-10-21 | 2011-05-17 | Alcon, Inc. | Drug delivery device |
| TR200201047T2 (tr) | 1999-10-21 | 2002-07-22 | Alcon, Inc. | İlaç verme vasıtası. |
| US6416777B1 (en) | 1999-10-21 | 2002-07-09 | Alcon Universal Ltd. | Ophthalmic drug delivery device |
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| US9603741B2 (en) | 2000-05-19 | 2017-03-28 | Michael S. Berlin | Delivery system and method of use for the eye |
| US8679089B2 (en) | 2001-05-21 | 2014-03-25 | Michael S. Berlin | Glaucoma surgery methods and systems |
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| US10857157B2 (en) | 2015-01-26 | 2020-12-08 | BioAxone BioSciences, Inc. | Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors |
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| WO2017004205A1 (en) | 2015-06-29 | 2017-01-05 | Reveragen Biopharma, Inc. | NON-HORMONAL STEROID MODULATORS OF NF-κB FOR TREATMENT OF DISEASE |
| JP6837475B2 (ja) | 2015-08-14 | 2021-03-03 | イバンティス インコーポレイテッド | 圧力センサを備えた眼用インプラントおよび送達システム |
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Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4975537A (en) * | 1985-10-23 | 1990-12-04 | The Upjohn Company | Δ9(11) -angiostatic steroids |
| US4771042A (en) * | 1985-11-25 | 1988-09-13 | The Upjohn Company | Inhibition of angiogenesis involving the coadministration of steroids with heparin or heparin fragments |
| US4876250A (en) * | 1988-10-31 | 1989-10-24 | Alcon Laboratories, Inc. | Methods for controlling ocular hypertension with angiostatic steroids |
| US5371078A (en) | 1988-10-31 | 1994-12-06 | Alcon Laboratories, Inc. | Angiostatic steroids and methods and compositions for controlling ocular hypertension |
| CA2081205C (en) * | 1990-06-11 | 2001-02-27 | John W. Wilks | Steroids which inhibit angiogenesis |
| WO1995024930A1 (en) * | 1994-03-14 | 1995-09-21 | Massachusetts Eye & Ear Infirmary | Use of green porphyrins in ocular diagnosis and therapy |
-
1997
- 1997-07-16 US US08/895,184 patent/US5770592A/en not_active Expired - Fee Related
-
1998
- 1998-06-18 CA CA002296558A patent/CA2296558A1/en not_active Abandoned
- 1998-06-18 WO PCT/US1998/012711 patent/WO1999003503A1/en not_active Ceased
- 1998-06-18 EP EP98931367A patent/EP1003553B1/de not_active Expired - Lifetime
- 1998-06-18 DK DK98931367T patent/DK1003553T3/da active
- 1998-06-18 US US09/445,237 patent/US6297228B1/en not_active Expired - Fee Related
- 1998-06-18 PT PT98931367T patent/PT1003553E/pt unknown
- 1998-06-18 ES ES98931367T patent/ES2224412T3/es not_active Expired - Lifetime
- 1998-06-18 AT AT98931367T patent/ATE274356T1/de not_active IP Right Cessation
- 1998-06-18 JP JP2000502798A patent/JP2001510170A/ja active Pending
- 1998-06-18 DE DE69825906T patent/DE69825906T2/de not_active Expired - Fee Related
- 1998-06-18 AU AU81515/98A patent/AU734195B2/en not_active Ceased
- 1998-06-18 BR BR9811012-8A patent/BR9811012A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2224412T3 (es) | 2005-03-01 |
| US5770592A (en) | 1998-06-23 |
| PT1003553E (pt) | 2004-10-29 |
| WO1999003503A1 (en) | 1999-01-28 |
| DE69825906T2 (de) | 2005-09-01 |
| DK1003553T3 (da) | 2004-09-20 |
| HK1028952A1 (en) | 2001-03-16 |
| DE69825906D1 (de) | 2004-09-30 |
| AU734195B2 (en) | 2001-06-07 |
| BR9811012A (pt) | 2000-10-17 |
| AU8151598A (en) | 1999-02-10 |
| JP2001510170A (ja) | 2001-07-31 |
| EP1003553B1 (de) | 2004-08-25 |
| US6297228B1 (en) | 2001-10-02 |
| EP1003553A1 (de) | 2000-05-31 |
| CA2296558A1 (en) | 1999-01-28 |
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