ATE274911T1 - Mikrogranulate von ursodeoxycholsäure - Google Patents

Mikrogranulate von ursodeoxycholsäure

Info

Publication number
ATE274911T1
ATE274911T1 AT02027185T AT02027185T ATE274911T1 AT E274911 T1 ATE274911 T1 AT E274911T1 AT 02027185 T AT02027185 T AT 02027185T AT 02027185 T AT02027185 T AT 02027185T AT E274911 T1 ATE274911 T1 AT E274911T1
Authority
AT
Austria
Prior art keywords
ursodeoxycholic acid
microgranulates
acid
ursodeoxycholic
microgranules
Prior art date
Application number
AT02027185T
Other languages
English (en)
Inventor
Loredana Cecchetelli
Rella Mario Di
Donatella Tedeschi
Original Assignee
Istituto Biochimico Italiano
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Biochimico Italiano filed Critical Istituto Biochimico Italiano
Application granted granted Critical
Publication of ATE274911T1 publication Critical patent/ATE274911T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT02027185T 2001-12-06 2002-12-05 Mikrogranulate von ursodeoxycholsäure ATE274911T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2001MI002572A ITMI20012572A1 (it) 2001-12-06 2001-12-06 Microgranuli di acido ursodesossicolico

Publications (1)

Publication Number Publication Date
ATE274911T1 true ATE274911T1 (de) 2004-09-15

Family

ID=11448667

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02027185T ATE274911T1 (de) 2001-12-06 2002-12-05 Mikrogranulate von ursodeoxycholsäure

Country Status (5)

Country Link
EP (1) EP1317925B1 (de)
AT (1) ATE274911T1 (de)
DE (1) DE60201117T2 (de)
ES (1) ES2227377T3 (de)
IT (1) ITMI20012572A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007518670A (ja) * 2003-12-15 2007-07-12 カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ 苦味のある薬物、及びｐＨ感受性ポリマーを含む風味マスクされた医薬組成物
EP1694303A1 (de) * 2003-12-15 2006-08-30 Council Of Scientific And Industrial Research Geschmacksmaskierte pharmazeutische zusammensetzung mit einem ph-sensitiven polymer
EP1890705B1 (de) 2005-05-12 2015-11-11 Medizinische Universität Graz Verwendung von 24-nor-UDCA zur Behandlung cholestatischer Lebererkrankungen
DE102008004893A1 (de) * 2008-01-17 2009-07-23 Add Technologies Ltd. Trägerpellets, Verfahren zu deren Herstellung und deren Verwendung
EP2468762A1 (de) 2010-11-30 2012-06-27 Dr. Falk Pharma Gmbh Optimierte Synthese von reinen, nichtpolymorphen, kristallinen Gallensäuren mit definierter Partikelgröße
CN109908088A (zh) * 2019-04-08 2019-06-21 合肥医工医药股份有限公司 一种采用脂质网状包合技术掩盖苦味的熊去氧胆酸制剂
CN110478304B (zh) * 2019-08-20 2022-07-05 广州市金熊大健康科技有限公司 一种含有熊胆微胶囊的牙膏

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1245890B (it) * 1991-04-12 1994-10-25 Alfa Wassermann Spa Formulazioni farmaceutiche per uso orale gastroresistenti contenenti acidi biliari.
IT1257793B (it) * 1992-05-18 1996-02-13 Composizione farmaceutica a base di acidi biliari in microgranuli a rilascio controllato
IT1255968B (it) * 1992-11-27 1995-11-17 Composizioni farmaceutiche contenenti acido ursodesossicolico
DE19906290A1 (de) * 1999-02-15 2000-08-17 Falk Pharma Gmbh Arzneimittel zur Behandlung bzw. Prävention von Darmkrebs

Also Published As

Publication number Publication date
DE60201117D1 (de) 2004-10-07
EP1317925B1 (de) 2004-09-01
ES2227377T3 (es) 2005-04-01
DE60201117T2 (de) 2005-09-01
ITMI20012572A1 (it) 2003-06-06
EP1317925A1 (de) 2003-06-11

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties