ATE275566T1 - Verfahren zur herstellung von 1,8- - Google Patents
Verfahren zur herstellung von 1,8-Info
- Publication number
- ATE275566T1 ATE275566T1 AT00931478T AT00931478T ATE275566T1 AT E275566 T1 ATE275566 T1 AT E275566T1 AT 00931478 T AT00931478 T AT 00931478T AT 00931478 T AT00931478 T AT 00931478T AT E275566 T1 ATE275566 T1 AT E275566T1
- Authority
- AT
- Austria
- Prior art keywords
- formula
- solvent
- producing
- alkyltryptophol
- tetrahydropyrano
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000002904 solvent Substances 0.000 abstract 2
- -1 1,8-disubstituted -1,3,4,9-tetrahydropyrano (3,4-b)-indole-1-acetic acid Chemical class 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000007789 gas Substances 0.000 abstract 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN865DE1999 | 1999-06-11 | ||
| US09/412,455 US6331638B1 (en) | 1999-10-04 | 1999-10-04 | Process for the preparation of 1,8-disubstituted-1,3,4,9-tetrahydropyrano (3,4-B)-indole-1-acetic acid esters |
| PCT/IB2000/000760 WO2000077006A1 (en) | 1999-06-11 | 2000-06-07 | Process for the preparation of 1,8-disubstituted-1,3,4,9-tetrahydropyrano (3,4-b)-indole-1-acetic acid esters in a hydroxylic solvent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE275566T1 true ATE275566T1 (de) | 2004-09-15 |
Family
ID=26324679
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00931478T ATE275566T1 (de) | 1999-06-11 | 2000-06-07 | Verfahren zur herstellung von 1,8- |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1198465B1 (de) |
| CN (1) | CN1355804A (de) |
| AT (1) | ATE275566T1 (de) |
| AU (1) | AU4942700A (de) |
| BR (1) | BR0011490A (de) |
| CA (1) | CA2375860A1 (de) |
| DE (1) | DE60013604T2 (de) |
| WO (1) | WO2000077006A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100497342C (zh) * | 2005-08-23 | 2009-06-10 | 杭州科本化工有限公司 | 1,8-二取代-1,3,4,9-四氢吡喃并（3,4-b)-吲哚-1-乙酸酯的制备方法 |
| WO2014003693A1 (en) * | 2012-06-25 | 2014-01-03 | Kucukguzel S Guniz | Etodolac derivatives as hcv ns5b polymerase inhibitors |
| CN111303172B (zh) * | 2020-03-18 | 2021-04-02 | 浙江外国语学院 | 一种制备依托度酸甲酯的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3939178A (en) * | 1971-06-01 | 1976-02-17 | American Home Products Corporation | Certain pyrano [3,4-b]indoles and thiopyrano[3,4-b]indoles |
| US4012417A (en) * | 1972-05-16 | 1977-03-15 | American Home Products Corporation | Process for preparing pyrano[3,4-b]indole or thio pyrano[3,4-b]indole derivatives |
| US4309348A (en) * | 1979-05-14 | 1982-01-05 | American Home Products Corporation | Tricyclic indole derivatives |
| US4585877A (en) * | 1985-05-06 | 1986-04-29 | American Home Products Corporation | Process for preparing 1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)-indole-1-acetic acid, etodolac |
-
2000
- 2000-06-07 CN CN00808769A patent/CN1355804A/zh active Pending
- 2000-06-07 EP EP00931478A patent/EP1198465B1/de not_active Expired - Lifetime
- 2000-06-07 BR BR0011490-1A patent/BR0011490A/pt not_active Application Discontinuation
- 2000-06-07 CA CA002375860A patent/CA2375860A1/en not_active Abandoned
- 2000-06-07 DE DE60013604T patent/DE60013604T2/de not_active Expired - Fee Related
- 2000-06-07 AU AU49427/00A patent/AU4942700A/en not_active Abandoned
- 2000-06-07 AT AT00931478T patent/ATE275566T1/de not_active IP Right Cessation
- 2000-06-07 WO PCT/IB2000/000760 patent/WO2000077006A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000077006A1 (en) | 2000-12-21 |
| DE60013604T2 (de) | 2005-09-22 |
| CA2375860A1 (en) | 2000-12-21 |
| EP1198465B1 (de) | 2004-09-08 |
| EP1198465A1 (de) | 2002-04-24 |
| CN1355804A (zh) | 2002-06-26 |
| DE60013604D1 (de) | 2004-10-14 |
| BR0011490A (pt) | 2002-04-23 |
| AU4942700A (en) | 2001-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |