ATE275571T1 - 2-n-substituierte- oder unsubstituierte 2-amino-5-methylpiperidin-3,4-diole und verfahren zu ihrer herstellung - Google Patents
2-n-substituierte- oder unsubstituierte 2-amino-5-methylpiperidin-3,4-diole und verfahren zu ihrer herstellungInfo
- Publication number
- ATE275571T1 ATE275571T1 AT00902059T AT00902059T ATE275571T1 AT E275571 T1 ATE275571 T1 AT E275571T1 AT 00902059 T AT00902059 T AT 00902059T AT 00902059 T AT00902059 T AT 00902059T AT E275571 T1 ATE275571 T1 AT E275571T1
- Authority
- AT
- Austria
- Prior art keywords
- methylpiperidine
- amino
- substituted
- diols
- unsubstituted
- Prior art date
Links
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- MUZQQSPLJRMNHT-KVTDHHQDSA-N (2r,3s,4r,5r)-2-amino-5-methylpiperidine-3,4-diol Chemical compound C[C@@H]1CN[C@@H](N)[C@H](O)[C@@H]1O MUZQQSPLJRMNHT-KVTDHHQDSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000612 phthaloyl group Chemical group C(C=1C(C(=O)*)=CC=CC1)(=O)* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2517599 | 1999-02-02 | ||
| PCT/JP2000/000572 WO2000046200A1 (en) | 1999-02-02 | 2000-02-02 | 2-n-substituted or unsubstituted-2-amino-5-methylpiperidine-3,4-diols and processes for the preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE275571T1 true ATE275571T1 (de) | 2004-09-15 |
Family
ID=12158683
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00902059T ATE275571T1 (de) | 1999-02-02 | 2000-02-02 | 2-n-substituierte- oder unsubstituierte 2-amino-5-methylpiperidin-3,4-diole und verfahren zu ihrer herstellung |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6610709B1 (de) |
| EP (1) | EP1156038B1 (de) |
| JP (1) | JP4598956B2 (de) |
| KR (1) | KR100692957B1 (de) |
| AT (1) | ATE275571T1 (de) |
| AU (1) | AU2324900A (de) |
| CA (1) | CA2362082C (de) |
| DE (1) | DE60013559T2 (de) |
| ES (1) | ES2228452T3 (de) |
| WO (1) | WO2000046200A1 (de) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5231185A (en) * | 1985-11-19 | 1993-07-27 | Cornell Research Foundation, Inc. | Monosaccharide analog-based glycosidase inhibitors |
| US5100797A (en) * | 1989-06-27 | 1992-03-31 | Monsanto Company | Fucosidase inhibitors |
| US5013842A (en) * | 1990-01-22 | 1991-05-07 | Monsanto Company | Synthesis of chiral pyrrolidine and piperidine glycosidase inhibitors |
| US5128347A (en) * | 1990-10-18 | 1992-07-07 | Monsanto Company | Glycosidase inhibiting 1,4-dideoxy-4-fluoronojirimycin |
| US5342951A (en) * | 1992-04-01 | 1994-08-30 | G.D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
| JPH09157254A (ja) * | 1995-12-01 | 1997-06-17 | Microbial Chem Res Found | ３−ヒドロキシメチル−３−デカルボキシシアスタチンｂ誘導体およびそれらの製造方法 |
-
2000
- 2000-02-02 EP EP00902059A patent/EP1156038B1/de not_active Expired - Lifetime
- 2000-02-02 ES ES00902059T patent/ES2228452T3/es not_active Expired - Lifetime
- 2000-02-02 KR KR1020017009746A patent/KR100692957B1/ko not_active Expired - Fee Related
- 2000-02-02 CA CA002362082A patent/CA2362082C/en not_active Expired - Fee Related
- 2000-02-02 AT AT00902059T patent/ATE275571T1/de not_active IP Right Cessation
- 2000-02-02 JP JP2000597271A patent/JP4598956B2/ja not_active Expired - Fee Related
- 2000-02-02 US US09/890,462 patent/US6610709B1/en not_active Expired - Fee Related
- 2000-02-02 AU AU23249/00A patent/AU2324900A/en not_active Abandoned
- 2000-02-02 DE DE60013559T patent/DE60013559T2/de not_active Expired - Lifetime
- 2000-02-02 WO PCT/JP2000/000572 patent/WO2000046200A1/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1156038B1 (de) | 2004-09-08 |
| CA2362082A1 (en) | 2000-08-10 |
| CA2362082C (en) | 2009-06-16 |
| DE60013559D1 (de) | 2004-10-14 |
| WO2000046200A1 (en) | 2000-08-10 |
| JP4598956B2 (ja) | 2010-12-15 |
| EP1156038A4 (de) | 2002-06-12 |
| EP1156038A1 (de) | 2001-11-21 |
| US6610709B1 (en) | 2003-08-26 |
| KR100692957B1 (ko) | 2007-03-12 |
| KR20010093319A (ko) | 2001-10-27 |
| ES2228452T3 (es) | 2005-04-16 |
| DE60013559T2 (de) | 2005-10-06 |
| AU2324900A (en) | 2000-08-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |