ATE275573T1 - Neue nukleosid-analoge die polyzyklische aromatische gruppen als substituenten haben, verfahren zu ihrer herstellung und ihre anwendungen - Google Patents

Neue nukleosid-analoge die polyzyklische aromatische gruppen als substituenten haben, verfahren zu ihrer herstellung und ihre anwendungen

Info

Publication number: ATE275573T1
Authority: AT; Austria
Prior art keywords: nucleic acids; polycyclic aromatic; nucleosides; substituents; applications
Prior art date: 1996-05-15

Application number

AT97925598T

Other languages

English (en)

Inventor

Eric T Kool

Original Assignee

Univ Rochester

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-15

Filing date

1997-05-15

Publication date

2004-09-15

1997-05-15 Application filed by Univ Rochester filed Critical Univ Rochester

2004-09-15 Application granted granted Critical

2004-09-15 Publication of ATE275573T1 publication Critical patent/ATE275573T1/de

Links

238000000034 method Methods 0.000 title abstract 2
229940127073 nucleoside analogue Drugs 0.000 title 1
150000007523 nucleic acids Chemical class 0.000 abstract 3
102000039446 nucleic acids Human genes 0.000 abstract 3
108020004707 nucleic acids Proteins 0.000 abstract 3
239000002777 nucleoside Substances 0.000 abstract 3
125000003835 nucleoside group Chemical group 0.000 abstract 3
MWPLVEDNUUSJAV-UHFFFAOYSA-N anthracene Chemical compound C1=CC=CC2=CC3=CC=CC=C3C=C21 MWPLVEDNUUSJAV-UHFFFAOYSA-N 0.000 abstract 2
238000005859 coupling reaction Methods 0.000 abstract 2
YNPNZTXNASCQKK-UHFFFAOYSA-N phenanthrene Chemical compound C1=CC=C2C3=CC=CC=C3C=CC2=C1 YNPNZTXNASCQKK-UHFFFAOYSA-N 0.000 abstract 2
BBEAQIROQSPTKN-UHFFFAOYSA-N pyrene Chemical compound C1=CC=C2C=CC3=CC=CC4=CC=C1C2=C43 BBEAQIROQSPTKN-UHFFFAOYSA-N 0.000 abstract 2
ASJSAQIRZKANQN-CRCLSJGQSA-N 2-deoxy-D-ribose Chemical compound OC[C@@H](O)[C@@H](O)CC=O ASJSAQIRZKANQN-CRCLSJGQSA-N 0.000 abstract 1
PJANXHGTPQOBST-VAWYXSNFSA-N Stilbene Natural products C=1C=CC=CC=1/C=C/C1=CC=CC=C1 PJANXHGTPQOBST-VAWYXSNFSA-N 0.000 abstract 1
XBDYBAVJXHJMNQ-UHFFFAOYSA-N Tetrahydroanthracene Natural products C1=CC=C2C=C(CCCC3)C3=CC2=C1 XBDYBAVJXHJMNQ-UHFFFAOYSA-N 0.000 abstract 1
150000001491 aromatic compounds Chemical class 0.000 abstract 1
238000006664 bond formation reaction Methods 0.000 abstract 1
230000008878 coupling Effects 0.000 abstract 1
238000010168 coupling process Methods 0.000 abstract 1
238000011067 equilibration Methods 0.000 abstract 1
GVEPBJHOBDJJJI-UHFFFAOYSA-N fluoranthrene Natural products C1=CC(C2=CC=CC=C22)=C3C2=CC=CC3=C1 GVEPBJHOBDJJJI-UHFFFAOYSA-N 0.000 abstract 1
239000012528 membrane Substances 0.000 abstract 1
SLIUAWYAILUBJU-UHFFFAOYSA-N pentacene Chemical compound C1=CC=CC2=CC3=CC4=CC5=CC=CC=C5C=C4C=C3C=C21 SLIUAWYAILUBJU-UHFFFAOYSA-N 0.000 abstract 1
125000005575 polycyclic aromatic hydrocarbon group Chemical group 0.000 abstract 1
239000000523 sample Substances 0.000 abstract 1
PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical compound C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 abstract 1
235000021286 stilbenes Nutrition 0.000 abstract 1
IFLREYGFSNHWGE-UHFFFAOYSA-N tetracene Chemical compound C1=CC=CC2=CC3=CC4=CC=CC=C4C=C3C=C21 IFLREYGFSNHWGE-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/04—Carbocyclic radicals
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Biotechnology (AREA)
Saccharide Compounds (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Furan Compounds (AREA)

AT97925598T 1996-05-15 1997-05-15 Neue nukleosid-analoge die polyzyklische aromatische gruppen als substituenten haben, verfahren zu ihrer herstellung und ihre anwendungen ATE275573T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1777296P	1996-05-15	1996-05-15
PCT/US1997/008307 WO1997043298A1 (en)	1996-05-15	1997-05-15	Novel nucleoside analogs with polycyclic aromatic groups attached, methods of synthesis and uses therefor

Publications (1)

Publication Number	Publication Date
ATE275573T1 true ATE275573T1 (de)	2004-09-15

Family

ID=21784456

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97925598T ATE275573T1 (de)	1996-05-15	1997-05-15	Neue nukleosid-analoge die polyzyklische aromatische gruppen als substituenten haben, verfahren zu ihrer herstellung und ihre anwendungen

Country Status (6)

Country	Link
EP (1)	EP0927188B1 (de)
JP (1)	JP2000511160A (de)
AT (1)	ATE275573T1 (de)
CA (1)	CA2253654C (de)
DE (1)	DE69730609D1 (de)
WO (1)	WO1997043298A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7135312B2 (en)	1993-04-15	2006-11-14	University Of Rochester	Circular DNA vectors for synthesis of RNA and DNA
US7033753B1 (en)	1999-01-15	2006-04-25	University Of Rochester	Compositions and methods for nonenzymatic ligation of oligonucleotides and detection of genetic polymorphisms
US6479650B1 (en)	1999-12-14	2002-11-12	Research Corporation Technologies, Inc.	Fluorescent nucleoside analogs and combinatorial fluorophore arrays comprising same
AU2001278145B2 (en)	2000-08-04	2006-09-14	Sensors For Medicine And Science, Inc.	Detection of analytes in aqueous environments
WO2003052134A2 (en) *	2001-12-18	2003-06-26	Human Genetic Signatures Pty Ltd	Oligonucleotides comprising intercalator pseudonucleotide(s) for detection of nucleic acids and mutants hereof
JP2004175708A (ja) *	2002-11-26	2004-06-24	Geneticlab Co Ltd	二環性ナフチリジンヌクレオシド
US7655809B2 (en)	2004-05-18	2010-02-02	University Of Ottawa	Compounds comprising a linear series of five fused carbon rings, and preparation thereof
US7935836B2 (en)	2004-05-18	2011-05-03	Alexander Graham Fallis	Compounds comprising a linear series of five fused carbon rings, and preparation thereof
EP3484908A4 (de)	2016-07-15	2020-04-08	AM Chemicals Llc	Nicht-nukleosidische feste träger und phosphoramiditbausteine für die oligonukleotidsynthese
EP4130001A1 (de) *	2021-08-03	2023-02-08	Studiengesellschaft Kohle mbH	Verfahren zur direkten katalytischen glycosylierung von arenen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0669928A1 (de) *	1993-08-18	1995-09-06	Chromagen, Inc.	Anwendung von fluoreszierenden n-nukleosiden und fluoreszierenden strukturanalogen von n-nukleosiden

1997
- 1997-05-15 WO PCT/US1997/008307 patent/WO1997043298A1/en not_active Ceased
- 1997-05-15 DE DE69730609T patent/DE69730609D1/de not_active Expired - Lifetime
- 1997-05-15 CA CA002253654A patent/CA2253654C/en not_active Expired - Fee Related
- 1997-05-15 EP EP97925598A patent/EP0927188B1/de not_active Expired - Lifetime
- 1997-05-15 JP JP09541138A patent/JP2000511160A/ja not_active Ceased
- 1997-05-15 AT AT97925598T patent/ATE275573T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2253654C (en)	2003-01-28
DE69730609D1 (de)	2004-10-14
WO1997043298A1 (en)	1997-11-20
CA2253654A1 (en)	1997-11-20
JP2000511160A (ja)	2000-08-29
EP0927188A1 (de)	1999-07-07
EP0927188B1 (de)	2004-09-08

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Legal Events

Date	Code	Title	Description
2005-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties