ATE277921T1 - Selektiv auf den cb2-rezeptor wirkende cannabinoide - Google Patents

Selektiv auf den cb2-rezeptor wirkende cannabinoide

Info

Publication number: ATE277921T1
Authority: AT; Austria
Prior art keywords: receptor; cannabinoids; cannabinoid; novel; ring
Prior art date: 1998-05-04

Application number

AT99921676T

Other languages

English (en)

Inventor

Alexandros Makriyannis

Atmaram Khanolkar

Dai Lu

Original Assignee

Univ Connecticut

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-05-04

Filing date

1999-05-04

Publication date

2004-10-15

1999-05-04 Application filed by Univ Connecticut filed Critical Univ Connecticut

2004-10-15 Application granted granted Critical

2004-10-15 Publication of ATE277921T1 publication Critical patent/ATE277921T1/de

Links

229930003827 cannabinoid Natural products 0.000 title abstract 6
239000003557 cannabinoid Substances 0.000 title abstract 6
229940065144 cannabinoids Drugs 0.000 title abstract 3
102000009135 CB2 Cannabinoid Receptor Human genes 0.000 abstract 1
108010073376 CB2 Cannabinoid Receptor Proteins 0.000 abstract 1
125000002837 carbocyclic group Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
210000000987 immune system Anatomy 0.000 abstract 1
230000001506 immunosuppresive effect Effects 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT99921676T 1998-05-04 1999-05-04 Selektiv auf den cb2-rezeptor wirkende cannabinoide ATE277921T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US8412998P	1998-05-04	1998-05-04
PCT/US1999/009806 WO1999057107A2 (en)	1998-05-04	1999-05-04	Cannabinoids selective for the cb2 receptor

Publications (1)

Publication Number	Publication Date
ATE277921T1 true ATE277921T1 (de)	2004-10-15

Family

ID=22183058

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99921676T ATE277921T1 (de)	1998-05-04	1999-05-04	Selektiv auf den cb2-rezeptor wirkende cannabinoide

Country Status (7)

Country	Link
US (1)	US6166066A (de)
EP (1)	EP1076653B1 (de)
AT (1)	ATE277921T1 (de)
CA (1)	CA2340444A1 (de)
DE (1)	DE69920683T2 (de)
ES (1)	ES2224658T3 (de)
WO (1)	WO1999057107A2 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE247097T1 (de) *	1998-05-04	2003-08-15	Univ Connecticut	Analgetische und immunomodulierende cannabinoiden
ATE277921T1 (de) *	1998-05-04	2004-10-15	Univ Connecticut	Selektiv auf den cb2-rezeptor wirkende cannabinoide
US7897598B2 (en)	1998-06-09	2011-03-01	Alexandros Makriyannis	Inhibitors of the anandamide transporter
US7589220B2 (en) *	1998-06-09	2009-09-15	University Of Connecticut	Inhibitors of the anandamide transporter
US7276613B1 (en)	1998-11-24	2007-10-02	University Of Connecticut	Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7161016B1 (en)	1998-11-24	2007-01-09	University Of Connecticut	Cannabimimetic lipid amides as useful medications
US20070179135A1 (en) *	2006-01-05	2007-08-02	Travis Craig R	Cannabinoid derivatives
US8084467B2 (en) *	1999-10-18	2011-12-27	University Of Connecticut	Pyrazole derivatives as cannabinoid receptor antagonists
US6900236B1 (en)	1999-10-18	2005-05-31	University Of Connecticut	Cannabimimetic indole derivatives
US7393842B2 (en) *	2001-08-31	2008-07-01	University Of Connecticut	Pyrazole analogs acting on cannabinoid receptors
US6943266B1 (en)	1999-10-18	2005-09-13	University Of Connecticut	Bicyclic cannabinoid agonists for the cannabinoid receptor
US7119108B1 (en) *	1999-10-18	2006-10-10	University Of Connecticut	Pyrazole derivatives as cannabinoid receptor antagonists
DE60033834T2 (de)	1999-10-18	2007-11-15	The University Of Connecticut, Farmington	Für periphäre cannabinoid-rezeptoren selektive liganden
US7741365B2 (en) *	1999-10-18	2010-06-22	University Of Connecticut	Peripheral cannabinoid receptor (CB2) selective ligands
US7235584B2 (en) *	2000-06-22	2007-06-26	Pharmos Corporation	Non-psychotropic cannabinoids
JP2004501145A (ja)	2000-06-22	2004-01-15	ファーモス　コーポレイション	向精神作用をもたない新規なカンナビノイド
CA2435409A1 (en) *	2001-01-26	2002-08-01	University Of Connecticut	Novel cannabimimetic ligands
CA2436133A1 (en)	2001-01-29	2002-08-08	University Of Connecticut	Receptor selective cannabimimetic aminoalkylindoles
EP1414775B1 (de) *	2001-07-13	2012-12-19	The University of Connecticut	Bicyclisches cannabinoid
US7666867B2 (en) *	2001-10-26	2010-02-23	University Of Connecticut	Heteroindanes: a new class of potent cannabimimetic ligands
US20040259936A1 (en) *	2001-12-07	2004-12-23	Nagarkatti Leonard C	Treatment of neoplasia
CA2478338A1 (en)	2002-03-08	2003-09-18	Signal Pharmaceuticals, Inc.	Combination therapy for treating, preventing or managing proliferative disorders and cancers
WO2004103410A1 (en) *	2002-06-06	2004-12-02	Yissum Research Development Company Of The Hebrew University Of Jerusalem	Methods compositions and articles of manufacture for modulating bone growth
WO2004017922A2 (en)	2002-08-23	2004-03-04	University Of Connecticut	Keto cannabinoids with therapeutic indications
IL160420A0 (en) *	2004-02-16	2004-07-25	Yissum Res Dev Co	Treating or preventing diabetes with cannabidiol
WO2005123053A2 (en) *	2004-06-22	2005-12-29	Pharmos Limited	Use of cb2 receptors agonists for the treatment of huntington’s disease
US7781650B2 (en) *	2007-04-30	2010-08-24	Monsanto Technology Llc	Plants and seeds of corn variety CV202909
US9575319B2 (en)	2014-03-10	2017-02-21	Ion Virtual Technology Corporation	Method and system for reducing motion blur when experiencing virtual or augmented reality environments
US10239808B1 (en)	2016-12-07	2019-03-26	Canopy Holdings, LLC	Cannabis extracts
DK3509638T3 (da)	2017-06-20	2022-04-11	Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd	Præparater med cannabidiolsyreestere og anvendelser deraf
CA3089994A1 (en)	2018-01-31	2019-08-08	Canopy Holdings, LLC	Hemp powder
CA3119729A1 (en)	2018-10-10	2020-04-16	Treehouse Biotech, Inc.	Synthesis of cannabigerol
EP3937925A1 (de)	2019-03-12	2022-01-19	EPM (IP), Inc.	Cannabidiolsäureesterzusammensetzungen und verwendungen davon

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3915996A (en) *	1972-10-16	1975-10-28	Abbott Lab	Process for making benzopyrans
US3886184A (en) *	1973-08-03	1975-05-27	Lilly Co Eli	Aminodibenzo(b,d)pyrans
US4833073A (en) *	1987-01-27	1989-05-23	Hoffmann-La Roche Inc.	Immunoassay for tetrahydrocannabinol metabolites
US5440052A (en) *	1993-08-06	1995-08-08	University Of Connecticut	Compositions useful as a cannabinoid receptor probe
FR2735774B1 (fr) *	1995-06-21	1997-09-12	Sanofi Sa	Utilisation de composes agonistes du recepteur cb2 humain pour la preparation de medicaments immunomodulateurs, nouveaux composes agonistes du recepteur cb2 et les compositions pharmaceutiques les contenant
US5688825A (en) *	1996-05-31	1997-11-18	University Of Connecticut	Anandamide amidase inhibitors as analgesic agents
ATE277921T1 (de) *	1998-05-04	2004-10-15	Univ Connecticut	Selektiv auf den cb2-rezeptor wirkende cannabinoide
ATE247097T1 (de) *	1998-05-04	2003-08-15	Univ Connecticut	Analgetische und immunomodulierende cannabinoiden

1999
- 1999-05-04 AT AT99921676T patent/ATE277921T1/de not_active IP Right Cessation
- 1999-05-04 WO PCT/US1999/009806 patent/WO1999057107A2/en not_active Ceased
- 1999-05-04 CA CA002340444A patent/CA2340444A1/en not_active Abandoned
- 1999-05-04 EP EP99921676A patent/EP1076653B1/de not_active Expired - Lifetime
- 1999-05-04 ES ES99921676T patent/ES2224658T3/es not_active Expired - Lifetime
- 1999-05-04 DE DE69920683T patent/DE69920683T2/de not_active Expired - Fee Related
- 1999-05-04 US US09/304,718 patent/US6166066A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
WO1999057107A2 (en)	1999-11-11
ES2224658T3 (es)	2005-03-01
US6166066A (en)	2000-12-26
WO1999057107A3 (en)	2000-02-03
EP1076653B1 (de)	2004-09-29
DE69920683T2 (de)	2005-04-07
CA2340444A1 (en)	1999-11-11
DE69920683D1 (de)	2004-11-04
EP1076653A2 (de)	2001-02-21

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Legal Events

Date	Code	Title	Description
2005-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties