ATE277939T1 - Uebergangsmetallkomplexe der vii-nebengruppe mit multidentaten aminopolycarboxylat-liganden und ein kit zu deren herstellung - Google Patents

Uebergangsmetallkomplexe der vii-nebengruppe mit multidentaten aminopolycarboxylat-liganden und ein kit zu deren herstellung

Info

Publication number
ATE277939T1
ATE277939T1 AT00952136T AT00952136T ATE277939T1 AT E277939 T1 ATE277939 T1 AT E277939T1 AT 00952136 T AT00952136 T AT 00952136T AT 00952136 T AT00952136 T AT 00952136T AT E277939 T1 ATE277939 T1 AT E277939T1
Authority
AT
Austria
Prior art keywords
compound
formula
ligands
ligand
aminopolycarboxylate
Prior art date
Application number
AT00952136T
Other languages
English (en)
Inventor
Mary M Dyszlewski
Roger Alberto
Joseph E Bugaj
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Application granted granted Critical
Publication of ATE277939T1 publication Critical patent/ATE277939T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT00952136T 1999-06-29 2000-06-28 Uebergangsmetallkomplexe der vii-nebengruppe mit multidentaten aminopolycarboxylat-liganden und ein kit zu deren herstellung ATE277939T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14098999P 1999-06-29 1999-06-29
PCT/US2000/017813 WO2001000637A1 (en) 1999-06-29 2000-06-28 Group (vii) transition-metal complexes with multidentate aminopolycarboxylate ligands and a kit for producing them

Publications (1)

Publication Number Publication Date
ATE277939T1 true ATE277939T1 (de) 2004-10-15

Family

ID=22493669

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00952136T ATE277939T1 (de) 1999-06-29 2000-06-28 Uebergangsmetallkomplexe der vii-nebengruppe mit multidentaten aminopolycarboxylat-liganden und ein kit zu deren herstellung

Country Status (10)

Country Link
EP (1) EP1192166B1 (de)
JP (1) JP2003503415A (de)
AT (1) ATE277939T1 (de)
AU (1) AU6488900A (de)
CA (1) CA2377018A1 (de)
CZ (1) CZ20014603A3 (de)
DE (1) DE60014375T2 (de)
ES (1) ES2223559T3 (de)
HU (1) HUP0301779A3 (de)
WO (1) WO2001000637A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6359119B1 (en) * 2000-05-24 2002-03-19 Mallinckrodt Inc. Formulation of Tc and Re carbonyl complexes using stannous ion as the reductant for pertechnetate and perrhenate
ATE424222T1 (de) * 2002-09-03 2009-03-15 Univ Zuerich Herstellung von m(co)3-komplexen durch festphasentechniken durch metal-unterstützte trennung vom festen träger
US7682601B2 (en) 2003-04-15 2010-03-23 Mallinckrodt Inc. Bifunctional tridentate pyrazolyl containing ligands for re and tc tricarbonyl complexes
EP1644050B1 (de) 2003-04-15 2010-06-09 Mallinckrodt Inc. Bifunktionale tridentate pyrazolyl-enthaltende liganden für re-, tc- und mn- tricarbonyl-komplexe
EP1618380B1 (de) * 2003-04-29 2009-12-30 Universität Zürich AN EINEM BIOMOLEKÜL GEBUNDENEN N epsilon- UND/ODER N alpha DERIVATISIERTEM UND ORGANISCH-GESCHÜTZTEM L-HISTIDIN ZUR HOCH-EFFIZIENTER MARKIERUNG MIT (M(H2O)3(CO)3)+ MITTELS FAC KOORDINIERUNG
US8986650B2 (en) 2005-10-07 2015-03-24 Guerbet Complex folate-NOTA-Ga68
CA2625196C (fr) 2005-10-07 2016-04-05 Guerbet Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium
GB0623482D0 (en) 2006-11-24 2007-01-03 Mallinckrodt Inc Technetium-99m (l) tricarbonyl complexes with tridentate chelators for myocardium imaging

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2150916T3 (es) * 1991-08-29 2000-12-16 Mallinckrodt Medical Inc Utilizacion del acido gentisico o del alcohol gentisilico para estabilizar peptidos y proteinas radiomarcados.
EP0879606A1 (de) * 1997-04-25 1998-11-25 Paul Scherrer Institut Verfahren zur Herstellung von facial Metall Tricarbonyl Verbindungen und ihre Anwendung zur Markierung von Biosubstraten
DE19860289C2 (de) * 1998-12-21 2003-11-13 Schering Ag Neue Chelatoren sowie deren Tricarbonyl-Komplexe mit Technetium und Rhenium

Also Published As

Publication number Publication date
JP2003503415A (ja) 2003-01-28
AU6488900A (en) 2001-01-31
DE60014375T2 (de) 2005-12-01
EP1192166B1 (de) 2004-09-29
HUP0301779A3 (en) 2008-01-28
CA2377018A1 (en) 2001-01-04
EP1192166A1 (de) 2002-04-03
DE60014375D1 (de) 2004-11-04
HUP0301779A2 (hu) 2003-08-28
CZ20014603A3 (cs) 2002-11-13
ES2223559T3 (es) 2005-03-01
WO2001000637A1 (en) 2001-01-04

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