ATE278681T1 - Dibenzofluorene derivative als antitumormittel - Google Patents

Dibenzofluorene derivative als antitumormittel

Info

Publication number: ATE278681T1
Authority: AT; Austria
Prior art keywords: formula; carbon atoms; group; substituted; tumor agent
Prior art date: 1998-12-01

Application number

AT99965865T

Other languages

English (en)

Inventor

Frederick F Becker

Bimal K Banik

Original Assignee

Univ Texas

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-01

Filing date

1999-11-22

Publication date

2004-10-15

1999-11-22 Application filed by Univ Texas filed Critical Univ Texas

2004-10-15 Application granted granted Critical

2004-10-15 Publication of ATE278681T1 publication Critical patent/ATE278681T1/de

Links

XNKVIGSNRYAOQZ-UHFFFAOYSA-N dibenzofluorene Chemical class C12=CC=CC=C2C2=CC=CC=C2C2=C1CC1=CC=CC=C12 XNKVIGSNRYAOQZ-UHFFFAOYSA-N 0.000 title abstract 2
239000002246 antineoplastic agent Substances 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 4
125000003368 amide group Chemical group 0.000 abstract 2
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT99965865T 1998-12-01 1999-11-22 Dibenzofluorene derivative als antitumormittel ATE278681T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/203,650 US6184224B1 (en)	1998-12-01	1998-12-01	Antitumor dibenzofluorene derivatives
PCT/US1999/027691 WO2000032583A1 (en)	1998-12-01	1999-11-22	Antitumor dibenzofluorene derivatives

Publications (1)

Publication Number	Publication Date
ATE278681T1 true ATE278681T1 (de)	2004-10-15

Family

ID=22754784

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99965865T ATE278681T1 (de)	1998-12-01	1999-11-22	Dibenzofluorene derivative als antitumormittel

Country Status (7)

Country	Link
US (3)	US6184224B1 (de)
EP (1)	EP1135379B1 (de)
JP (1)	JP2002531445A (de)
AT (1)	ATE278681T1 (de)
CA (1)	CA2352878A1 (de)
DE (1)	DE69920953T2 (de)
WO (1)	WO2000032583A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6849348B2 (en) *	2002-12-31	2005-02-01	Eastman Kodak Company	Complex fluorene-containing compounds
US20050107430A1 (en) *	2003-10-29	2005-05-19	Banik Bimal K.	Antimicrobial and antiviral compounds
JP5030534B2 (ja) *	2006-11-01	2012-09-19	出光興産株式会社	アミノジベンゾフルオレン誘導体及びそれを用いた有機エレクトロルミネッセンス素子

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA743137A (en)		1966-09-20	Bui-Quoc-Huong	Preparation of 6-aminochrysene and the use thereof

1998
- 1998-12-01 US US09/203,650 patent/US6184224B1/en not_active Expired - Fee Related
1999
- 1999-11-22 AT AT99965865T patent/ATE278681T1/de not_active IP Right Cessation
- 1999-11-22 EP EP99965865A patent/EP1135379B1/de not_active Expired - Lifetime
- 1999-11-22 WO PCT/US1999/027691 patent/WO2000032583A1/en not_active Ceased
- 1999-11-22 CA CA002352878A patent/CA2352878A1/en not_active Abandoned
- 1999-11-22 DE DE69920953T patent/DE69920953T2/de not_active Expired - Fee Related
- 1999-11-22 JP JP2000585225A patent/JP2002531445A/ja not_active Withdrawn
2000
- 2000-08-08 US US09/634,102 patent/US6362200B1/en not_active Expired - Fee Related
2002
- 2002-01-14 US US10/047,301 patent/US6479662B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
WO2000032583A9 (en)	2000-11-30
CA2352878A1 (en)	2000-06-08
US6362200B1 (en)	2002-03-26
DE69920953T2 (de)	2006-02-23
US6479662B2 (en)	2002-11-12
DE69920953D1 (de)	2004-11-11
US20020103191A1 (en)	2002-08-01
EP1135379A1 (de)	2001-09-26
US6184224B1 (en)	2001-02-06
EP1135379B1 (de)	2004-10-06
WO2000032583A1 (en)	2000-06-08
JP2002531445A (ja)	2002-09-24

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Legal Events

Date	Code	Title	Description
2005-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties