DE69920953D1 - Dibenzofluorene derivative als antitumormittel - Google Patents

Dibenzofluorene derivative als antitumormittel

Info

Publication number
DE69920953D1
DE69920953D1 DE69920953T DE69920953T DE69920953D1 DE 69920953 D1 DE69920953 D1 DE 69920953D1 DE 69920953 T DE69920953 T DE 69920953T DE 69920953 T DE69920953 T DE 69920953T DE 69920953 D1 DE69920953 D1 DE 69920953D1
Authority
DE
Germany
Prior art keywords
formula
carbon atoms
group
substituted
antituary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69920953T
Other languages
English (en)
Other versions
DE69920953T2 (de
Inventor
F Becker
K Banik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
University of Texas at Austin
Original Assignee
University of Texas System
University of Texas at Austin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Texas System, University of Texas at Austin filed Critical University of Texas System
Application granted granted Critical
Publication of DE69920953D1 publication Critical patent/DE69920953D1/de
Publication of DE69920953T2 publication Critical patent/DE69920953T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69920953T 1998-12-01 1999-11-22 Dibenzofluorene derivative als antitumormittel Expired - Fee Related DE69920953T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/203,650 US6184224B1 (en) 1998-12-01 1998-12-01 Antitumor dibenzofluorene derivatives
US203650 1998-12-01
PCT/US1999/027691 WO2000032583A1 (en) 1998-12-01 1999-11-22 Antitumor dibenzofluorene derivatives

Publications (2)

Publication Number Publication Date
DE69920953D1 true DE69920953D1 (de) 2004-11-11
DE69920953T2 DE69920953T2 (de) 2006-02-23

Family

ID=22754784

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69920953T Expired - Fee Related DE69920953T2 (de) 1998-12-01 1999-11-22 Dibenzofluorene derivative als antitumormittel

Country Status (7)

Country Link
US (3) US6184224B1 (de)
EP (1) EP1135379B1 (de)
JP (1) JP2002531445A (de)
AT (1) ATE278681T1 (de)
CA (1) CA2352878A1 (de)
DE (1) DE69920953T2 (de)
WO (1) WO2000032583A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6849348B2 (en) * 2002-12-31 2005-02-01 Eastman Kodak Company Complex fluorene-containing compounds
US20050107430A1 (en) * 2003-10-29 2005-05-19 Banik Bimal K. Antimicrobial and antiviral compounds
JP5030534B2 (ja) * 2006-11-01 2012-09-19 出光興産株式会社 アミノジベンゾフルオレン誘導体及びそれを用いた有機エレクトロルミネッセンス素子

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA743137A (en) 1966-09-20 Bui-Quoc-Huong Preparation of 6-aminochrysene and the use thereof

Also Published As

Publication number Publication date
WO2000032583A9 (en) 2000-11-30
CA2352878A1 (en) 2000-06-08
US6362200B1 (en) 2002-03-26
DE69920953T2 (de) 2006-02-23
US6479662B2 (en) 2002-11-12
US20020103191A1 (en) 2002-08-01
ATE278681T1 (de) 2004-10-15
EP1135379A1 (de) 2001-09-26
US6184224B1 (en) 2001-02-06
EP1135379B1 (de) 2004-10-06
WO2000032583A1 (en) 2000-06-08
JP2002531445A (ja) 2002-09-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee